Page last updated: 2024-10-15

dinitrochlorobenzene and Itching

dinitrochlorobenzene has been researched along with Itching in 15 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Research Excerpts

ExcerptRelevanceReference
"Our findings suggest that pamoic acid activation of peripheral GPR35 can contribute to the improvement of pruritus and its associated diseases."8.31Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)
"Pruritic dermatitis is a disease with a considerable unmet need for treatment and appears to present with not only epidermal but also peripheral neuronal complications."5.91Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)
"Our findings suggest that pamoic acid activation of peripheral GPR35 can contribute to the improvement of pruritus and its associated diseases."4.31Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)
" Itch responses were evoked by histamine, chloroquine, and dinitrochlorobenzene-induced contact dermatitis (CD)."3.88GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way. ( Han, MK; Im, SY; Im, YN; Kim, HK; Lee, HK; Lee, YD; Park, JS; Song, HR, 2018)
"Pruritic dermatitis is a disease with a considerable unmet need for treatment and appears to present with not only epidermal but also peripheral neuronal complications."1.91Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's7 (46.67)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Oh, JS1
Seong, GS2
Kim, YD1
Choung, SY2
Jeong, NH1
Lee, S1
Choi, YA1
Song, KS1
Kim, SH2
Kim, C1
Kim, Y1
Lim, JY1
Kim, M2
Zheng, H1
Hwang, SW1
Jang, S1
Ohn, J1
Kim, JW1
Kang, SM1
Jeon, D1
Heo, CY1
Lee, YS1
Kwon, O1
Kim, KH1
Zeng, D1
Chen, C1
Zhou, W2
Ma, X1
Pu, X1
Zeng, Y1
Lv, F1
Peng, G1
Mu, Z1
Cui, L1
Liu, P1
Wang, Y1
Wu, W1
Han, X1
Im, YN1
Lee, YD1
Park, JS1
Kim, HK1
Im, SY1
Song, HR1
Lee, HK1
Han, MK1
Choi, YY1
Kim, MH1
Lee, H1
Jo, SY1
Yang, WM1
Park, SJ1
Lee, YH1
Lee, KH1
Kim, TJ1
Schüttenhelm, BN1
Duraku, LS1
Dijkstra, JF1
Walbeehm, ET1
Holstege, JC1
Muñoz, FC1
Cervantes, MM1
Cervantes-García, D1
Jiménez, M1
Ventura-Juárez, J1
Salinas, E1
Han, SC1
Kang, GJ1
Ko, YJ1
Kang, HK1
Moon, SW1
Ann, YS1
Yoo, ES1
Laidlaw, A1
Flecknell, P1
Rees, JL1
McDaniel, DH1
Blatchley, DM1
Welton, WA1

Other Studies

15 other studies available for dinitrochlorobenzene and Itching

ArticleYear
Deacetylasperulosidic Acid Ameliorates Pruritus, Immune Imbalance, and Skin Barrier Dysfunction in 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis NC/Nga Mice.
    International journal of molecular sciences, 2021, Dec-25, Volume: 23, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Chemokines; Dermatitis, Atopic; Dinitrochlorobenzene; Filaggrin P

2021
Inhibitory Effects of Euscaphic Acid in the Atopic Dermatitis Model by Reducing Skin Inflammation and Intense Pruritus.
    Inflammation, 2022, Volume: 45, Issue:4

    Topics: Animals; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Animal; Inflammation;

2022
Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis.
    British journal of pharmacology, 2023, Volume: 180, Issue:23

    Topics: Animals; Dermatitis; Dinitrochlorobenzene; Ganglia, Spinal; Pruritus; Skin

2023
Fermented
    Nutrients, 2020, Jan-18, Volume: 12, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Mode

2020
Caffeoyl-Pro-His amide relieve DNCB-Induced Atopic Dermatitis-Like phenotypes in BALB/c mice.
    Scientific reports, 2020, 05-21, Volume: 10, Issue:1

    Topics: Amides; Animals; Antioxidants; Caffeic Acids; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; E

2020
TRPA1 deficiency alleviates inflammation of atopic dermatitis by reducing macrophage infiltration.
    Life sciences, 2021, Feb-01, Volume: 266

    Topics: Acetanilides; Animals; Dermatitis, Atopic; Dinitrochlorobenzene; Inflammation; Macrophages; Mast Cel

2021
Anti-IL-33 Antibody Has a Therapeutic Effect in an Atopic Dermatitis Murine Model Induced by 2, 4-Dinitrochlorobenzene.
    Inflammation, 2018, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Animals; Anti-Allergic Agents; Antibodies; Case-Control Studies; Chemotaxis; Chil

2018
GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:8

    Topics: Animals; Cell Line; Chloroquine; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal;

2018
(R)-(+)-pulegone suppresses allergic and inflammation responses on 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice model.
    Journal of dermatological science, 2018, Volume: 91, Issue:3

    Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cyclohexane Monoterpenes; Cytokines; Dermat

2018
Effect of eriodictyol on the development of atopic dermatitis-like lesions in ICR mice.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:8

    Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Behavior, Animal; Dermatitis, Atopic; Dinit

2013
Differential Changes in the Peptidergic and the Non-Peptidergic Skin Innervation in Rat Models for Inflammation, Dry Skin Itch, and Dermatitis.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:8

    Topics: Acetone; Animals; Biopsy; Calcitonin Gene-Related Peptide; Dermatitis; Dinitrochlorobenzene; Disease

2015
Glycomacropeptide Attenuates Inflammation, Pruritus, and Th2 Response Associated with Atopic Dermatitis Induced by 2,4-Dinitrochlorobenzene in Rat.
    Journal of immunology research, 2017, Volume: 2017

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caseins; Dermatitis, Atopic; Dinitrochlorobenzene;

2017
Fermented fish oil suppresses T helper 1/2 cell response in a mouse model of atopic dermatitis via generation of CD4+CD25+Foxp3+ T cells.
    BMC immunology, 2012, Aug-09, Volume: 13

    Topics: Animals; Cell Differentiation; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models,

2012
Production of acute and chronic itch with histamine and contact sensitizers in the mouse and guinea pig.
    Experimental dermatology, 2002, Volume: 11, Issue:4

    Topics: Acute Disease; Animals; Capsaicin; Chronic Disease; Dinitrochlorobenzene; Disease Models, Animal; Fe

2002
Adverse systemic reaction to dinitrochlorobenzene.
    Archives of dermatology, 1982, Volume: 118, Issue:6

    Topics: Adult; Alopecia Areata; Dinitrochlorobenzene; Dyspepsia; Humans; Male; Nitrobenzenes; Pruritus; Urti

1982