dinitrochlorobenzene has been researched along with Hypersensitivity in 49 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven thymectomized and ten non-thymectomized patients with myasthenia gravis, matched with respect to sex, age, duration and severity of the disease were investigated with respect to routine clinical features, electrophysiological examination, HLA-typing, auto-antibodies, lymphocyte subpopulations in peripheral blood, Concanavalin A-induced release of leucocyte migration inhibitory factor (LIF), in vitro lymphocyte activation by mitogens and antigens and response to primary immunization with dinitrochlorobenzene measured in vivo and in vitro." | 3.66 | Immunological studies in thymectomized and non-thymectomized patients with myasthenia gravis. ( Andersen, V; Bendtzen, K; Fulpius, BW; Krarup, C; Monnier, VM; Permin, H; Platz, P; Søeberg, B; Sørensen, SF; Thomsen, M, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (81.63) | 18.7374 |
| 1990's | 3 (6.12) | 18.2507 |
| 2000's | 2 (4.08) | 29.6817 |
| 2010's | 3 (6.12) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Mäki-Opas, I | 1 |
| Hämäläinen, M | 1 |
| Moilanen, LJ | 1 |
| Sood, H | 1 |
| Leppänen, T | 1 |
| Kummola, L | 1 |
| Junttila, IS | 1 |
| Lehtimäki, L | 1 |
| Moilanen, E | 1 |
| Alyoussef, A | 1 |
| Saito, K | 1 |
| Takenouchi, O | 1 |
| Nukada, Y | 1 |
| Miyazawa, M | 1 |
| Sakaguchi, H | 1 |
| Goutet, M | 1 |
| Pépin, E | 1 |
| Langonné, I | 1 |
| Huguet, N | 1 |
| Ban, M | 1 |
| Vandebriel, RJ | 1 |
| De Jong, WH | 1 |
| Hendriks, JJ | 1 |
| Van Loveren, H | 1 |
| SKOG, E | 5 |
| KUBICZ, J | 1 |
| NILZEN, A | 1 |
| WIKSTROM, K | 1 |
| POLAK, L | 3 |
| GOTZ, H | 2 |
| SCHULZ, H | 2 |
| EISEN, HN | 1 |
| TABACHNICK, M | 1 |
| FICHTELIUS, KE | 1 |
| GRIMMER, H | 1 |
| ROSENBERG, EW | 1 |
| FISCHER, RW | 1 |
| FREY, JR | 2 |
| DE WECK, AL | 1 |
| GELEICK, H | 1 |
| GROTH, O | 2 |
| KLASCHKA, F | 1 |
| KIND, PD | 1 |
| BOCOBO, FC | 1 |
| CURTIS, AC | 1 |
| BULALA, P | 1 |
| SEEBERG, G | 1 |
| HAXTHAUSEN, H | 2 |
| ANDREASEN, E | 1 |
| Bridges, BA | 1 |
| Heid, E | 1 |
| Grosshans, E | 1 |
| Laplanche, G | 1 |
| Caussade, P | 1 |
| Redzepagić, B | 1 |
| Tomasević, M | 1 |
| Zildzić, V | 1 |
| Koster, F | 1 |
| Gaffar, A | 1 |
| Jackson, TM | 1 |
| Pukhlik, BM | 1 |
| Gandzeĭchuk, TV | 1 |
| Lishchanovskaia, GI | 1 |
| Stepanchuk, NA | 1 |
| Bannikov, EA | 1 |
| Bakhtilin, VIa | 1 |
| Gerasimova, NM | 1 |
| Kardakova, TA | 1 |
| Skoog, ML | 1 |
| Huang, J | 1 |
| Wang, XP | 1 |
| Chen, BM | 1 |
| Zhou, XJ | 1 |
| Matsushita, T | 1 |
| Gaspard, I | 1 |
| Kerdine, S | 1 |
| Pallardy, M | 1 |
| Lebrec, H | 1 |
| Plitnick, LM | 1 |
| Loveless, SE | 1 |
| Ladics, GS | 1 |
| Holsapple, MP | 1 |
| Selgrade, MJ | 1 |
| Sailstad, DM | 1 |
| Smialowicz, RJ | 1 |
| Levis, WR | 1 |
| Powell, JA | 1 |
| Whalen, JJ | 1 |
| Zajaczkowski, J | 1 |
| Pituch, A | 1 |
| Kolanowska, H | 1 |
| Michalik, R | 1 |
| Bürkle, PA | 1 |
| Tönnesmann, E | 1 |
| Ahnefeld, S | 1 |
| Nobbe, F | 1 |
| Federlin, K | 1 |
| Wilson, JD | 1 |
| Benfield, JR | 1 |
| Shors, E | 1 |
| Schick, P | 1 |
| Byfield, PE | 1 |
| Okita, M | 1 |
| Sørensen, SF | 1 |
| Andersen, V | 1 |
| Bendtzen, K | 1 |
| Fulpius, BW | 1 |
| Krarup, C | 1 |
| Monnier, VM | 1 |
| Permin, H | 1 |
| Platz, P | 1 |
| Søeberg, B | 1 |
| Thomsen, M | 1 |
| Lesovoĭ, VS | 1 |
| Saiamov, SR | 1 |
| Sachar, DB | 1 |
| Taub, RN | 1 |
| Ramachandar, K | 1 |
| Meyers, S | 1 |
| Forman, SP | 1 |
| Douglas, SD | 1 |
| Janowitz, HD | 1 |
| Ivanov, VV | 1 |
| Meier, G | 1 |
| Nelius, D | 1 |
| Stobbe, H | 1 |
| Friedmann, PS | 1 |
3 reviews available for dinitrochlorobenzene and Hypersensitivity
| Article | Year |
|---|---|
Some DNA-repair-deficient human syndromes and their implications for human health.
Topics: Adolescent; Ataxia Telangiectasia; Cockayne Syndrome; Dinitrochlorobenzene; DNA Repair; Dwarfism; Fe | 1981 |
[Dinitrochlorobenzene. Therapeutic use].
Topics: Alopecia Areata; Carcinoma, Basal Cell; Dermatitis, Contact; Dinitrochlorobenzene; Humans; Hypersens | 1984 |
Graded continuity, or all or none--studies of the human immune response.
Topics: Dermatitis, Contact; Dinitrochlorobenzene; Dose-Response Relationship, Immunologic; Humans; Hypersen | 1991 |
1 trial available for dinitrochlorobenzene and Hypersensitivity
| Article | Year |
|---|---|
Recovery of cellular immune competence during treatment of protein-calorie malnutrition.
Topics: Blood Proteins; Child; Child, Preschool; Dinitrochlorobenzene; Humans; Hypersensitivity; Immunocompe | 1981 |
45 other studies available for dinitrochlorobenzene and Hypersensitivity
| Article | Year |
|---|---|
TRPA1 Mediates Contact Hypersensitivity Induced by 2,4-Dinitrochlorobenzene.
Topics: Dermatitis, Contact; Dinitrochlorobenzene; Humans; Hypersensitivity; TRPA1 Cation Channel | 2023 |
Blocking TGF-β type 1 receptor partially reversed skin tissue damage in experimentally induced atopic dermatitis in mice.
Topics: Animals; Antioxidants; Benzamides; Biomarkers; Caspase 3; Dermatitis, Atopic; Dinitrochlorobenzene; | 2018 |
An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Activating Transcription Factor 3; Allergens; Animal | 2017 |
Identification of contact and respiratory sensitizers according to IL-4 receptor α expression and IL-2 production.
Topics: Allergens; Animals; Dinitrochlorobenzene; Female; Flow Cytometry; Hypersensitivity; Immunoglobulin E | 2012 |
Impact of exposure duration by low molecular weight compounds on interferon-gamma and interleukin-4 mRNA expression and production in the draining lymph nodes of mice.
Topics: Allergens; Animals; Concanavalin A; Dinitrochlorobenzene; Enzyme-Linked Immunosorbent Assay; Female; | 2003 |
Experimental studies on hypersensitivity to 2, 4-dinitrochlorobenzene and tuberculin in animals. I. Passive transfer of hypersensitivity to 2, 4-dinitrochlorobenzene.
Topics: Animals; Dinitrochlorobenzene; Hypersensitivity; Nitrobenzenes; Tuberculin | 1955 |
[Factors influencing time of development and topography of allergy after dinitrochlorobenzene in guinea pigs].
Topics: Animals; Dinitrochlorobenzene; Fetus; Guinea Pigs; Hypersensitivity; Nitrobenzenes | 1955 |
Experimental studies on hypersensitivity to 2, 4-dinitrochlorobenzene and tuberculin in animals. III. Parabiosis experiments.
Topics: Animals; Dinitrochlorobenzene; Hypersensitivity; Nitrobenzenes; Parabiosis; Tuberculin | 1955 |
Experimental studies on hypersensitivity to 2, 4-dinitrochlorobenzene and tuberculin in animals. II. Passive transfer of tuberculin sensitivity.
Topics: Animals; Dinitrochlorobenzene; Hypersensitivity; Nitrobenzenes; Tuberculin | 1955 |
Experimental studies on hypersensitivity to 2, 4-dinitrochlorobenzene and tuberculin in animals. IV. Intracutaneous passive transfer of sensitivity to 2, 4-dinitrochlorobenzene and tuberculin.
Topics: Animals; Dinitrochlorobenzene; Hypersensitivity; Nitrobenzenes; Tuberculin; Tuberculin Test | 1955 |
Factors influencing the skin reaction in guinea pigs sensitized with 2, 4-dinitrochlorobenzene.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Cold Temperature; Cortisone; Dinitrochlorobenzene; | 1955 |
Experimental studies on hypersensitivity to 2, 4-dinitrochlorobenzene and tuberculin in animals. V. Passive transfer experiments with lysed cells.
Topics: Animals; Dinitrochlorobenzene; Hypersensitivity; Nitrobenzenes; Tuberculin; Tuberculin Test | 1956 |
[Participation of mesenchymal cells (lymphocytes and monocytes) in the pathogenesis of skin sensitization in guinea pigs with dinitrochlorobenzene].
Topics: Animals; Dinitrochlorobenzene; Guinea Pigs; Humans; Hypersensitivity; Lymphocytes; Monocytes; Nitrob | 1956 |
[Participation of mesenchymal cells (lymphocytes and monocytes) in the pathogenesis of skin sensitization in guinea pigs with dinitrochlorobenzene].
Topics: Animals; Dinitrochlorobenzene; Guinea Pigs; Humans; Hypersensitivity; Lymphocytes; Monocytes; Nitrob | 1956 |
[Participation of mesenchymal cells (lymphocytes and monocytes) in the pathogenesis of skin sensitization in guinea pigs with dinitrochlorobenzene].
Topics: Animals; Dinitrochlorobenzene; Guinea Pigs; Humans; Hypersensitivity; Lymphocytes; Monocytes; Nitrob | 1956 |
[Participation of mesenchymal cells (lymphocytes and monocytes) in the pathogenesis of skin sensitization in guinea pigs with dinitrochlorobenzene].
Topics: Animals; Dinitrochlorobenzene; Guinea Pigs; Humans; Hypersensitivity; Lymphocytes; Monocytes; Nitrob | 1956 |
[Relations of fungus infection to epidermal dinitrochlorobenzene sensitization in guinea pigs].
Topics: Animals; Dinitrochlorobenzene; Fungi; Guinea Pigs; Hypersensitivity; Immune System Diseases; Mycoses | 1956 |
[Relations of fungus infection to epidermal dinitrochlorobenzene sensitization in guinea pigs].
Topics: Animals; Dinitrochlorobenzene; Fungi; Guinea Pigs; Hypersensitivity; Immune System Diseases; Mycoses | 1956 |
[Relations of fungus infection to epidermal dinitrochlorobenzene sensitization in guinea pigs].
Topics: Animals; Dinitrochlorobenzene; Fungi; Guinea Pigs; Hypersensitivity; Immune System Diseases; Mycoses | 1956 |
[Relations of fungus infection to epidermal dinitrochlorobenzene sensitization in guinea pigs].
Topics: Animals; Dinitrochlorobenzene; Fungi; Guinea Pigs; Hypersensitivity; Immune System Diseases; Mycoses | 1956 |
[Effects of central nervous inhibition and excitation on the dinitrochlorobenzene sensitization of guinea pigs].
Topics: Animals; Central Nervous System; Dinitrochlorobenzene; Guinea Pigs; Humans; Hypersensitivity; Nervou | 1957 |
Elicitation of allergic contact dermatitis in the guinea pig; the distribution of bound dinitrobenzene groups within the skin and quantitative determination of the extent of combination of 2,4-dinitro-chlorobenzene with epidermal protein in vivo.
Topics: Animals; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Contact; Dinitrobenzenes; Dinitrochlo | 1958 |
The influence on lymphocytes of sensitization to dinitrochlorobenzene shown by transfusion of labelled lymphocytes.
Topics: Dinitrochlorobenzene; Humans; Hypersensitivity; Lymphocytes; Nitrobenzenes | 1959 |
[The histology of epicutaneous test reaction in non-epicutaneous ("extracutaneous") sensitization with 2,4-dinitrochlorobenzene].
Topics: Dinitrochlorobenzene; Histological Techniques; Hypersensitivity; Immune System Diseases; Nitrobenzen | 1961 |
DNCB ALLERGY IN THE GUINEA PIG COLON.
Topics: Animals; Colonic Diseases; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; Dinitrophenols; Gu | 1964 |
IMMUNOLOGICAL UNRESPONSIVENESS IN ALLERGIC CONTACT DEMATITIS TO DINITROCHLOROBENZENE IN GUINEA PIGS.
Topics: Animals; Antigen-Antibody Reactions; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; Guinea P | 1964 |
STUDIES ON CONTACT SKIN REACTIONS AND NORMAL SKIN OF PASSIVELY SENSITIZED GUINEA-PIGS. I. A HISTOLOGICAL STUDY OF TEST LESIONS IN RECIPIENTS AFTER PASSIVE TRANSFER OF DINITROCHLOROBENZENE (DNCB) HYPERSENSITIVITY WITH LYMPHOID CELLS.
Topics: Animals; Autoradiography; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; DNA; Guinea Pigs; H | 1963 |
[ANIMAL EXPERIMENTAL STUDIES ON CONTACT ECZEMA. I. HISTOLOGY OF THE EPICUTANEOUS 2,4-DINITROCHLOROBENZENE SKIN REACTION IN GUINEA PIGS SENSITIZED INTRAPERITONEALLY BY THE LANDSTEINER TECHNIC].
Topics: Anaphylaxis; Animals; Dermatitis, Contact; Desensitization, Immunologic; Dinitrochlorobenzene; Freun | 1964 |
CELLULAR PASSIVE TRANSFER OF CONTACT HYPERSENSITIVITY TO PARAPHENYLENEDIAMINE AND TO 2,4-DINITROCHLOROBENZENE IN GUINEA PIGS.
Topics: Aniline Compounds; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Guinea Pigs; Haptens; Hyperse | 1965 |
[Quantitative studies on epidermal sensitization with dinitrochlorobenzene in guinea pigs].
Topics: Animals; Chlorobenzenes; Dinitrochlorobenzene; Epidermis; Guinea Pigs; Humans; Hypersensitivity; Ski | 1951 |
Eczematogenous sensitization via the lymphatic glands as compared with other routes; a study with 2:4 dinitrochlorobenzene.
Topics: Dinitrochlorobenzene; Hypersensitivity; Lymph Nodes; Nitrobenzenes | 1951 |
Passive transmission of dinitrochlorobenzene allergy with white blood cells from sensitized guinea-pigs.
Topics: Dinitrochlorobenzene; Guinea Pigs; Hypersensitivity; Leukocyte Count; Leukocytes; Nitrobenzenes | 1951 |
Lymph node response to cutaneous sensitization with dinitrochlorobenzene.
Topics: Dinitrochlorobenzene; Eczema; Humans; Hypersensitivity; Lymph Nodes | 1951 |
[Importance of the correlation of the DNCB and T lymphocyte test in the evaluation of cellular immunity in various forms of glomerulonephritis].
Topics: Dinitrochlorobenzene; Glomerulonephritis; Humans; Hypersensitivity; Immunity, Cellular; Nitrobenzene | 1983 |
[Sensitivity to tuberculin and dinitrochlorobenzene].
Topics: Dinitrochlorobenzene; Female; Humans; Hypersensitivity; Male; Nitrobenzenes; Skin Tests; Tuberculin | 1982 |
[Immunological characteristics of the parallergic reactions developing in a combination of experimental mycosis and dermatitis due to dinitrochlorobenzene].
Topics: Animals; Cell Adhesion; Dermatitis, Contact; Dinitrochlorobenzene; Guinea Pigs; Hypersensitivity; Im | 1981 |
The cellular infiltrate in experimental allergic and toxic contact dermatitis. Effect of systemically administered corticosteroids.
Topics: Acanthosis Nigricans; Adrenal Cortex Hormones; Animals; Dermatitis, Contact; Dinitrochlorobenzene; E | 1981 |
Dose-response relationships for chemical sensitization from TDI and DNCB.
Topics: Administration, Inhalation; Administration, Topical; Animals; Cytoplasmic Granules; Dinitrochloroben | 1993 |
Quantitation of cytokine mRNA expression as an endpoint for prediction and diagnosis of xenobiotic-induced hypersensitivity reactions.
Topics: Animals; Cytokines; Dendritic Cells; Dinitrochlorobenzene; Drug Hypersensitivity; Gene Expression; H | 1999 |
Cytokine profiling for chemical sensitizers: application of the ribonuclease protection assay and effect of dose.
Topics: Allergens; Animals; Asthma; Cytokines; Dinitrochlorobenzene; Dose-Response Relationship, Immunologic | 2002 |
Carrier specificity vs hapten specificity in classical cell-mediated contact sensitivity to dinitrochlorobenzene.
Topics: Carrier Proteins; Dermatitis, Contact; Dinitrochlorobenzene; Epitopes; Haptens; Humans; Hypersensiti | 1975 |
Some immunological aspects of the long-term remission in acute lymphoblastic leukemia in children.
Topics: Adolescent; Adult; Child; Child, Preschool; Dinitrochlorobenzene; Humans; Hypersensitivity; Immunogl | 1975 |
[Experiences with DNCB sensitization in normal human individuals of various age groups (author's transl)].
Topics: Age Factors; Dinitrochlorobenzene; Humans; Hypersensitivity; Immunity, Cellular; Immunologic Memory; | 1976 |
Skin testing in the assessment of cell-mediated immunity.
Topics: Adolescent; Adult; Aged; Antigens; Child; Dinitrochlorobenzene; Humans; Hypersensitivity; Immunity, | 1977 |
Monitoring of immunosuppression in beagles.
Topics: Animals; Antibodies; Azathioprine; Carcinoma, Bronchogenic; Dinitrochlorobenzene; Disease Models, An | 1977 |
Immunological studies in thymectomized and non-thymectomized patients with myasthenia gravis.
Topics: Adolescent; Adult; Aged; Autoantibodies; Autoimmune Diseases; Connective Tissue Diseases; Dinitrochl | 1978 |
[Modification of the contact test with 2,4-dinitrochlorobenzene and its use in evaluating the state of cellular immunity during the vaccinal process].
Topics: Animals; Coccidioidin; Cricetinae; Dinitrochlorobenzene; Hypersensitivity; Immunity, Cellular; Mice; | 1979 |
T and B lymphocytes and cutaneous anergy in inflammatory bowel disease.
Topics: Azathioprine; B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hyper | 1976 |
[Study of the parallergizing action on the skin of various synthetic detergents].
Topics: Animals; Detergents; Dinitrochlorobenzene; Drug Hypersensitivity; Guinea Pigs; Hypersensitivity; Ski | 1975 |
[Detection of age-dependent differences of cellular immunity using the dinitrochlorbenzeme epicutaneous test].
Topics: Adult; Age Factors; Aged; Antibody Formation; Dinitrochlorobenzene; Humans; Hypersensitivity; Immuni | 1975 |
Letter: Dinitrochlorobenzene test for anergy.
Topics: Dinitrochlorobenzene; Humans; Hypersensitivity; Nitrobenzenes; Skin Tests | 1976 |