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dinitrochlorobenzene and Head and Neck Neoplasms

dinitrochlorobenzene has been researched along with Head and Neck Neoplasms in 31 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)

Research Excerpts

ExcerptRelevanceReference
" There was no correlation between delayed hypersensitivity skin reaction to 2--4 dinitrochlorobenzene (DNCB) and titer values."3.66Epstein-Barr virus (EBV) antibody in patients treated by radical radiotherapy for head and neck cancer. ( Foster, N; Ghossein, NA; Halili, MR; Spigland, I, 1978)
", decreased responsiveness to several dilutions of phytohemagglutinin and lack of development of delayed hypersensitivity to 2,4-dinitrochlorobenzene (70% of patients were DNCB (-))."3.66Immunologic evaluation of patients with advanced head and neck cancer receiving weekly chemoimmunotherapy. ( Calcaterra, T; Dorey, F; Fahey, JL; Parker, NH; Ward, P; Zighelboim, J, 1979)
"Delayed hypersensitivity to dinitrochlorobenzene (DNCB) was tested prior to radiation therapy in 206 patients with solid tumors."3.65Delayed hypersensitivity to DNCB and survival following radiation therapy in patients with solid malignant tumors. ( Hazra, TA; Inalsingh, A; Parks, LC; Peeples, W, 1975)
"Delayed hypersensitivity, as determined by skin reactivity to 2-4 dinitrochlorobenzene (DNCB), was tested in 112 patients prior to their undergoing curative radiotherapy."3.65Delayed hypersensitivity in patients treated by curative radiotherapy. Its relation to tumor response and short-term survival. ( Bosworth, JL; Brooks, TL; Ghossein, NA, 1975)
"Of 107 patients with cancer of the head and neck region in whom sensitization with dinitrochlorobenzene (DNCB) was attempted at the time the patient first presented, 57 became positive while 50 remained negative."1.26Prognostic value of skin testing with dinitrochlorobenzene in patients with head and neck cancer. ( Clark, RM; Kersey, PA; Osoba, D; Rosen, IB, 1980)
"There was no correlation between delayed hypersensitivity skin reaction to 2--4 dinitrochlorobenzene (DNCB) and titer values."1.26Epstein-Barr virus (EBV) antibody in patients treated by radical radiotherapy for head and neck cancer. ( Foster, N; Ghossein, NA; Halili, MR; Spigland, I, 1978)
"Patients with mucosal squamous cell carcinoma of the head and neck generally have suppressed T cell function, and this suppression tends to be more pronounced with progression of disease."1.26Immunologic evaluation and prognosis in patients with head and neck cancer. ( Hilal, EY; Middleman, P; Oettgen, HF; Pinsky, CM; Strong, EW; Wanebo, HJ, 1977)
"Forty-three patients with squamous cell carcinoma of the head and neck were evaluated immunologically at various times before and after treatment."1.26Cellular immunity in patients with epidermoid cancer of the head and neck. ( Borowiecki, B; Croft, CB; Emeson, EE; Kukwa, A; Papenhausen, PR; Silver, C, 1979)
"Patients with advanced head and neck cancer have significant reduction in their circulating lymphocyte mass which is reflected in decreased numbers of T cells, Fc receptor cells, and in derangements of T lymphocyte functions, i."1.26Immunologic evaluation of patients with advanced head and neck cancer receiving weekly chemoimmunotherapy. ( Calcaterra, T; Dorey, F; Fahey, JL; Parker, NH; Ward, P; Zighelboim, J, 1979)
"The immune reactivity of 100 head and neck cancer patients was studied by means of DNCB, candidine, blastic transformation with PHA, and lymphocyte counts."1.26Cell-mediated immune response in head and neck cancer patients. ( Feierstein, J; Glait, H; Guardo, A; Olivari, A; Pradier, R; Rojas, A, 1976)
"The immune reactivity of patients with squamous carcinoma of the head and neck region was compared with that of patients with squamous carcinoma of the female pelvic organs and patients with adenocarcinomas, melanomas, and sarcomas."1.25Unique immunobiological aspects of head and neck squamous carcinoma. ( Chretien, PB, 1975)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199031 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deregibus, P1
Battezzati, G1
Katz, AE1
Bier, J2
Nicklisch, U2
Brookes, GB1
Clifford, P1
Osoba, D1
Kersey, PA1
Clark, RM1
Rosen, IB1
Bertino, JR1
Boston, B1
Capizzi, RL1
Chretien, PB2
Stefano, S1
Kerman, R1
Abbate, J1
Halili, MR1
Spigland, I1
Foster, N1
Ghossein, NA3
Hilal, EY3
Wanebo, HJ6
Pinsky, CM4
Middleman, P1
Strong, EW4
Oettgen, HF4
Papenhausen, PR1
Kukwa, A1
Croft, CB1
Borowiecki, B1
Silver, C1
Emeson, EE1
Zighelboim, J1
Dorey, F1
Parker, NH1
Calcaterra, T1
Ward, P1
Fahey, JL1
Browder, JP1
Bitter, K1
Mike, V2
Hirshaut, Y1
Olivari, AJ1
Glait, HM1
Guardo, A2
Califano, L1
Pradier, R2
Palmer, DL1
Eilber, FR1
Gilbert, HA1
Kagan, AR1
Miles, J1
Flores, L1
Nussbaum, H1
Rao, AR1
Chan, P1
Beattie, EJ1
Olivari, A1
Feierstein, J1
Glait, H1
Rojas, A1
Bosworth, JL2
Thaler, S1
Cunningham, TJ1
Antemann, R1
Paonessa, D1
Sponzo, RW1
Steiner, D1
Jun, MY1
Oettgen, H1
Hazra, TA1
Parks, LC1
Inalsingh, A1
Peeples, W1
Brooks, TL1
Parker, R1
Alexander, S1
Shaheen, OH1
Parkes, P1
Davis, RK1
Mandel, MA1
Kiehn, C1

Reviews

3 reviews available for dinitrochlorobenzene and Head and Neck Neoplasms

ArticleYear
Immunobiologic staging of patients with carcinoma of the head and neck.
    The Laryngoscope, 1983, Volume: 93, Issue:4

    Topics: Adult; Age Factors; Aged; Antibody Formation; Dinitrochlorobenzene; Female; Head and Neck Neoplasms;

1983
Immune reactivity in head and neck squamous carcinoma and relevance to the design of immunotherapy trials.
    Seminars in oncology, 1977, Volume: 4, Issue:4

    Topics: BCG Vaccine; Carcinoma, Squamous Cell; Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Immuni

1977
Unspecific cellular immunity before therapy in patients with squamous cell carcinoma of head and neck.
    Journal of maxillofacial surgery, 1978, Volume: 6, Issue:2

    Topics: Adult; Aged; B-Lymphocytes; Carcinoma, Squamous Cell; Dinitrochlorobenzene; Female; Head and Neck Ne

1978

Trials

4 trials available for dinitrochlorobenzene and Head and Neck Neoplasms

ArticleYear
Randomized trial of levamisole in patients with squamous cancer of the head and neck: a preliminary report.
    Cancer treatment reports, 1978, Volume: 62, Issue:11

    Topics: Carcinoma, Squamous Cell; Central Nervous System; Clinical Trials as Topic; Digestive System; Dinitr

1978
Adjuvant trial of levamisole in patients with squamous cancer of the head and neck: a preliminary report.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Antigens, Bacterial; Antigens, Fungal; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dinitroch

1978
Levamisole in squamous cell carcinoma of the head and neck.
    Cancer treatment reports, 1979, Volume: 63, Issue:6

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dinitrochlorobenzene; Female; Head

1979
Delayed hypersensitivity and local control of patients treated by radiotherapy for head and neck cancer.
    American journal of surgery, 1976, Volume: 132, Issue:1

    Topics: Adult; Aged; Animals; Clinical Trials as Topic; Dinitrochlorobenzene; Female; Head and Neck Neoplasm

1976

Other Studies

24 other studies available for dinitrochlorobenzene and Head and Neck Neoplasms

ArticleYear
[2 cases of sebaceous cancer observed at the Holy Spirit Hospital in Casale Monferrato in 1980].
    Minerva medica, 1982, Feb-11, Volume: 73, Issue:5

    Topics: Adenoma; Aged; Anal Gland Neoplasms; Animals; Bleomycin; Diagnosis, Differential; Dinitrochlorobenze

1982
[Investigations of unspecific immune reactivity in patients with head and neck carcinoma (author's transl)].
    Archives of oto-rhino-laryngology, 1981, Volume: 232, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Dinitrochlorobenzene; Female; Head and

1981
Nutritional status and general immune competence in patients with head and neck cancer.
    Journal of the Royal Society of Medicine, 1981, Volume: 74, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Humans; Hyper

1981
Prognostic value of skin testing with dinitrochlorobenzene in patients with head and neck cancer.
    Canadian journal of surgery. Journal canadien de chirurgie, 1980, Volume: 23, Issue:1

    Topics: Adult; Aged; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Humans; Hypersensitivity, Delaye

1980
The role of chemotherapy in the management of cancer of the head and neck: a review.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Bleomycin; Dinitrochlorobenzene; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Head and Neck

1975
Unique immunobiological aspects of head and neck squamous carcinoma.
    Canadian journal of otolaryngology, 1975, Volume: 4, Issue:2

    Topics: Antibody Formation; Antigen-Antibody Reactions; Carcinoma, Squamous Cell; Cells, Cultured; Complemen

1975
Serial studies of immunocompetence in head and neck cancer patients undergoing radiation therapy.
    AJR. American journal of roentgenology, 1976, Volume: 126, Issue:4

    Topics: Adult; Aged; Antibody Formation; Antigens, Neoplasm; B-Lymphocytes; Carcinoma, Squamous Cell; Dinitr

1976
Epstein-Barr virus (EBV) antibody in patients treated by radical radiotherapy for head and neck cancer.
    Journal of surgical oncology, 1978, Volume: 10, Issue:5

    Topics: Antibodies, Viral; Capsid; Carcinoma, Squamous Cell; Dinitrochlorobenzene; Female; Head and Neck Neo

1978
Immunologic evaluation and prognosis in patients with head and neck cancer.
    American journal of surgery, 1977, Volume: 134, Issue:4

    Topics: Carcinoma, Squamous Cell; Concanavalin A; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Hum

1977
Cellular immunity in patients with epidermoid cancer of the head and neck.
    The Laryngoscope, 1979, Volume: 89, Issue:4

    Topics: B-Lymphocytes; Carcinoma, Squamous Cell; Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Immu

1979
Immunologic evaluation of patients with advanced head and neck cancer receiving weekly chemoimmunotherapy.
    Cancer, 1979, Volume: 44, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Humans; H

1979
Immunologic testing as a guide to cancer management.
    The Surgical clinics of North America, 1979, Volume: 59, Issue:2

    Topics: Antibody Formation; Antigen-Antibody Complex; Breast Neoplasms; Colonic Neoplasms; Complement System

1979
Alcohol consumption and cellular immunocompetence.
    The Laryngoscope, 1978, Volume: 88, Issue:1 Pt 2 Sup

    Topics: Alcohol Drinking; Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Immunity, Cellular; Immunos

1978
General immune competence in cancer patients--head and neck.
    The Laryngoscope, 1978, Volume: 88, Issue:1 Pt 2 Sup

    Topics: Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Immunity; Immunosuppression Therapy

1978
The usefulness of pretreatment DNCB in 85 patients with squamous cell carcinoma of the upper aerodigestive tract.
    Journal of surgical oncology, 1978, Volume: 10, Issue:1

    Topics: Carcinoma, Squamous Cell; Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Leukocyte Count; Ly

1978
Immunocompetence testing in patients with one of the four common operable cancers--a review.
    Clinical bulletin, 1978, Volume: 8, Issue:1

    Topics: Breast Neoplasms; Colonic Neoplasms; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Humans;

1978
Cell-mediated immune response in head and neck cancer patients.
    Journal of surgical oncology, 1976, Volume: 8, Issue:4

    Topics: Aged; Antifungal Agents; Candida albicans; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Hu

1976
Adjuvant immuno- and/or chemotherapy with neuraminidase-treated autogenous tumor vaccine and Bacillus Calmette-Guérin for head and neck cancers.
    Annals of the New York Academy of Sciences, 1976, Volume: 277, Issue:00

    Topics: Antigens, Neoplasm; BCG Vaccine; Dinitrochlorobenzene; Head and Neck Neoplasms; Humans; Immunotherap

1976
T-cell deficiency in patients with squamous cell cancer of the head and neck.
    American journal of surgery, 1975, Volume: 130, Issue:4

    Topics: Alcoholism; B-Lymphocytes; Carcinoma, Squamous Cell; Concanavalin A; Dinitrochlorobenzene; Fluoresce

1975
Delayed hypersensitivity to DNCB and survival following radiation therapy in patients with solid malignant tumors.
    Radiology, 1975, Volume: 115, Issue:2

    Topics: Adenocarcinoma; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous Cell; Dinitrochlorobenzen

1975
Delayed hypersensitivity in patients treated by curative radiotherapy. Its relation to tumor response and short-term survival.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Dinitrochlorobenzene; Female; Genital Neoplasms, Female; Head; Head and Nec

1975
On the immunology of head and neck cancer--a prognostic index. Preliminary communication.
    The Journal of laryngology and otology, 1975, Volume: 89, Issue:7

    Topics: Antibody Formation; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Humans; Lymphocyte Activa

1975
Prognostic variables in head and neck cancer. Tumor site, stage, nodal status, differentiation, and immune status.
    Otolaryngologic clinics of North America, 1985, Volume: 18, Issue:3

    Topics: Dinitrochlorobenzene; DNA, Neoplasm; Head and Neck Neoplasms; Humans; Immunity, Cellular; Immunoglob

1985
Cutaneous reactivity in patients with cancer of the head and neck region.
    Surgical forum, 1973, Volume: 24

    Topics: Age Factors; Aged; Carcinoma, Squamous Cell; Croton Oil; Dinitrochlorobenzene; Drug Hypersensitivity

1973