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dinitrochlorobenzene and Graves Disease

dinitrochlorobenzene has been researched along with Graves Disease in 1 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

Research Excerpts

ExcerptRelevanceReference
"All patients developed a reaction of delayed hypersensitivity to DNCB."6.64Peripheral blood T and B lymphocytes, in vitro stimulation with phytohemagglutinin, and sensitization with 2,4-dinitrochlorobenzene in Grave's disease. ( Maciel, RM; Mendes, NF; Miki, SS; Nicolau, W, 1976)
"All patients developed a reaction of delayed hypersensitivity to DNCB."2.64Peripheral blood T and B lymphocytes, in vitro stimulation with phytohemagglutinin, and sensitization with 2,4-dinitrochlorobenzene in Grave's disease. ( Maciel, RM; Mendes, NF; Miki, SS; Nicolau, W, 1976)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maciel, RM1
Miki, SS1
Nicolau, W1
Mendes, NF1

Trials

1 trial available for dinitrochlorobenzene and Graves Disease

ArticleYear
Peripheral blood T and B lymphocytes, in vitro stimulation with phytohemagglutinin, and sensitization with 2,4-dinitrochlorobenzene in Grave's disease.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:3

    Topics: Adolescent; Adult; B-Lymphocytes; Clinical Trials as Topic; Dinitrochlorobenzene; Female; Graves Dis

1976