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dinitrochlorobenzene and Experimental Neoplasms

dinitrochlorobenzene has been researched along with Experimental Neoplasms in 27 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Research Excerpts

ExcerptRelevanceReference
"This set of experiments was devised to determine the effects of the commonly employed anesthetic induction agent, thiopental, on the incidence of pulmonary metastases in a murine fibrosarcoma system."7.65Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977)
"This was correlated with an impaired delayed hypersensitivity reaction to the de novo antigen."5.26Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977)
"An empirically established chemoimmunotherapy that combines the epifocal application of the contact sensitizer dinitrochlorobenzene (DNCB) to cutaneous metastases with the systemic administration of dacarbazine (DTIC) yields high response rates and results in prolonged survival."3.71Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model. ( Becker, JC; Bröcker, EB; Fischer, WH; Lutz, WK; Wack, C, 2001)
" No statistically significant difference in delayed hypersensitivity response to dinitrochlorobenzene was found between indomethacin-treated, tumor-bearing and control groups."3.67Indomethacin and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in the hamster buccal pouch. ( Gould, AR; Grant, FT; Miller, RL; Perry, DA, 1985)
" An early transient depression of two reactions in UV-irradiated mice occurred: delayed hypersensitivity to dinitrochlorobenzene measured by footpad swelling and the graft-versus-host reaction in UV-irradiated recipients measured by the use of the popliteal lymph node weight gain assay."3.65In vivo immune responses of mice during carcinogenesis by ultraviolet irradiation. ( Beard, J; Fisher, MS; Jessup, JM; Kripke, ML; Lofgreen, JS, 1977)
"This set of experiments was devised to determine the effects of the commonly employed anesthetic induction agent, thiopental, on the incidence of pulmonary metastases in a murine fibrosarcoma system."3.65Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977)
"This set of experiments was designed to evaluate the effects of thiabendazole (TBZ), a relatively nontoxic thiazole derivative, on the delayed hypersensitivity response of normal mice, tumor-bearing mice, and mice immunosuppressed by radiation and chemotherapy."3.65Thiabendazole: a potential adjuvant in cancer therapy. ( Conran, P; Goldblatt, PJ; Lovett, EJ; Lundy, J, 1976)
"Limited evidence suggests that prostatic cancer cells express antigens that are immunogenic in the host."2.36Immunobiology of carcinoma of the prostate. ( Catalona, WJ, 1980)
"Immunotherapy for prostatic cancer has not been adequately studied."2.36Immunobiology of carcinoma of the prostate. ( Catalona, WJ, 1980)
"The results suggest that gastrointestinal neoplasms may respond at least as well as other tumours."2.35Tumour immunology and the gut. ( Calman, KC, 1975)
"Indomethacin was not observed to produce any significant effect upon hamster buccal pouch carcinogenesis."1.27Indomethacin and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in the hamster buccal pouch. ( Gould, AR; Grant, FT; Miller, RL; Perry, DA, 1985)
"This was correlated with an impaired delayed hypersensitivity reaction to the de novo antigen."1.26Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental. ( Conran, P; Lovett, EJ; Lundy, J, 1977)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199026 (96.30)18.7374
1990's0 (0.00)18.2507
2000's1 (3.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jessup, JM6
Pellis, NR1
Kahan, BD1
Takeuchi, R1
Hori, M1
Catalona, WJ1
von Ardenne, M1
Reitnauer, PG1
Krüger, W1
Johnson, DK1
Pontes, JE1
Izbicki, R1
Pierce, JM1
Lovett, EJ3
Alderman, J1
Munster, E1
Lundy, J3
Wack, C1
Becker, JC1
Bröcker, EB1
Lutz, WK1
Fischer, WH1
Kripke, ML2
Lofgreen, JS1
Beard, J1
Fisher, MS1
Calman, KC1
Marshack, M1
Toto, P1
Kerman, R1
Murphy, JB1
Giunta, JL1
Mohammad, AR2
Conran, P2
Bean, MA1
Shah, SA2
Dickson, JA2
Hanna, N1
Palaszynski, E1
Mcdonald, JS1
Mincer, HH1
Lamm, DL1
Harris, SC1
Gittes, RF1
Cohen, MH3
Goldblatt, PJ1
Tomaszewski, MM1
Felix, EL1
Riggs, C1
Vanwijck, R1
Bouillenne, C1
Malek-Mansour, S1
Gould, AR1
Miller, RL1
Grant, FT1
Perry, DA1

Reviews

5 reviews available for dinitrochlorobenzene and Experimental Neoplasms

ArticleYear
Immunobiology of carcinoma of the prostate.
    Investigative urology, 1980, Volume: 17, Issue:5

    Topics: Acid Phosphatase; Animals; Antigens, Neoplasm; Carcinoembryonic Antigen; Dinitrochlorobenzene; Human

1980
Tumour immunology and the gut.
    Gut, 1975, Volume: 16, Issue:6

    Topics: alpha-Fetoproteins; Animals; Antibody Formation; Antigens, Neoplasm; BCG Vaccine; Carcinoembryonic A

1975
Some immunological considerations relevant to the study of human bladder cancer.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Aged; Animals; Antigens, Neoplasm; Cross Reactions; Cytotoxicity Tests, Immunologic; Dinitrochlorobe

1977
Effect of hyperthermia on the immunocompetence of VX2 tumor-bearing rabbits.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: Animals; Antibodies, Neoplasm; Antibody Formation; Antigens, Neoplasm; Dinitrochlorobenzene; Electro

1978
The immunobiology of colorectal cancer.
    Seminars in oncology, 1976, Volume: 3, Issue:4

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; BCG Vaccine; Carcinoembryonic Antigen; Colonic N

1976

Other Studies

22 other studies available for dinitrochlorobenzene and Experimental Neoplasms

ArticleYear
The spleen as a source of nonspecific suppressor cells in the tumor-bearing mouse.
    The Journal of surgical research, 1980, Volume: 28, Issue:5

    Topics: Animals; Dinitrochlorobenzene; Fibrosarcoma; Hypersensitivity, Delayed; Mice; Neoplasms, Experimenta

1980
[Effect of contact hypersensitivity on experimental carcinogenesis (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1980, Volume: 90, Issue:14

    Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Mice; Mice, Inbred Strains; Neoplasms, Experimen

1980
[20-methylcholanthrene-induced mice skin cancer: Part 3: Studies on co-carcinogenic and suppressive factors (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1981, Volume: 91, Issue:1

    Topics: Animals; Croton Oil; Dinitrochlorobenzene; Immunosuppression Therapy; Male; Methylcholanthrene; Mice

1981
2-Cyanoethyl urea and its derivatives as potential immunostimulants in experimental cancer therapy.
    Archiv fur Geschwulstforschung, 1981, Volume: 51, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Neoplasm; Antibody Formation; Antibody-Producing Cells;

1981
Prophylaxis of FANFT induced bladder tumours in rats by intravesical DNCB instillation.
    Urological research, 1980, Volume: 8, Issue:1

    Topics: Administration, Topical; Animals; Carcinoma, Transitional Cell; Dinitrochlorobenzene; FANFT; Female;

1980
Suppressive effects of thiopental and halothane on specific arms of the immune response.
    Journal of surgical oncology, 1980, Volume: 15, Issue:4

    Topics: Anesthesia; Animals; Dinitrochlorobenzene; Drug Synergism; Female; Fibrosarcoma; Halothane; Hypersen

1980
Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model.
    Melanoma research, 2001, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Dinitrochloroben

2001
In vivo immune responses of mice during carcinogenesis by ultraviolet irradiation.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:4

    Topics: Animals; Antigens, Neoplasm; Dinitrochlorobenzene; Graft Rejection; Graft vs Host Reaction; Hypersen

1977
Immunotherapy of chemically-induced tumors in the hamster cheek pouch with dinitrochlorobenzene.
    Journal of dental research, 1978, Volume: 57, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cheek; Cricetinae; Dinitrochlor

1978
The effect of dinitrochlorobenzene (DNCB) on dimethylbenzathracene (DMBA) carcinogenesis on hamster buccal pouch.
    Oral surgery, oral medicine, and oral pathology, 1978, Volume: 46, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Carcinoma; C

1978
Immunologic manipulation of DMBA tumorigenesis in hamster cheek pouch by DNCB contact hypersensitivity.
    Journal of oral pathology, 1979, Volume: 8, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Allergens; Animals; Cricetinae; Dinitroch

1979
Pulmonary metastases, a potential biologic consequence of anesthetic-induced immunosuppression by thiopental.
    Surgery, 1977, Volume: 82, Issue:2

    Topics: Anesthetics; Animals; Dinitrochlorobenzene; Fibrosarcoma; Hypersensitivity, Delayed; Immunosuppressi

1977
Mechanisms of depressed reactivity to dinitrochlorobenzene and ultraviolet-induced tumors during ultraviolet carcinogenesis in BALB/c mice.
    Cellular immunology, 1978, Volume: 38, Issue:1

    Topics: Animals; Dinitrochlorobenzene; Female; Graft Rejection; Hypersensitivity, Delayed; Immunity, Cellula

1978
Effect of hyperthermia on the immune response of normal rabbits.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: Animals; Antibody Formation; Dinitrochlorobenzene; Hyperthermia, Induced; Immunity; Immunity, Cellul

1978
Dinitrochlorobenzene contact hypersensitivity in the hamster cheek pouch.
    Journal of oral pathology, 1976, Volume: 5, Issue:3

    Topics: Animals; Cheek; Cricetinae; Dinitrochlorobenzene; Disease Models, Animal; Drug Hypersensitivity; Fem

1976
Bacillus Calmette-Guérin and dinitrochlorobenzene immunotherapy of chemically induced bladder tumors.
    Investigative urology, 1977, Volume: 14, Issue:5

    Topics: Animals; BCG Vaccine; Dinitrochlorobenzene; FANFT; Female; Immunization; Methods; Neoplasms, Experim

1977
Effects of murine tumors upon delayed hypersensitivity to dinitrochlorobenzene. II. Transitory delayed hypersensitivity in tumor-bearing mice.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:4

    Topics: Animals; Antigens; Dinitrochlorobenzene; Female; Fibrosarcoma; Hypersensitivity, Delayed; Immunizati

1977
Thiabendazole: a potential adjuvant in cancer therapy.
    Surgery, 1976, Volume: 80, Issue:5

    Topics: Animals; Ascitic Fluid; Dinitrochlorobenzene; Doxorubicin; Female; Hypersensitivity, Delayed; Immuni

1976
Effects of murine tumors on delayed hypersensitivity to dinitrochlorobenzene. I. Description of anergy caused by transplanted tumors.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:5

    Topics: Animals; Dinitrochlorobenzene; Female; Fibrosarcoma; Hypersensitivity, Delayed; Immune Tolerance; Im

1976
Enhancement of tumor growth by dinitrochlorobenzene (DNCB).
    Surgical forum, 1976, Volume: 27, Issue:62

    Topics: Animals; Dinitrochlorobenzene; Immunity, Cellular; Lymphoma; Mice; Mice, Inbred BALB C; Neoplasm Tra

1976
Potentiation and arming of lymphocyte mediated immunity by sera from melanoma patients.
    European journal of cancer, 1975, Volume: 11, Issue:4

    Topics: Agglutination Tests; Antibodies, Anti-Idiotypic; Cell Line; Cytotoxicity Tests, Immunologic; Dinitro

1975
Indomethacin and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in the hamster buccal pouch.
    Journal of oral pathology, 1985, Volume: 14, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cheek; Cricetinae; Dinitrochlorobenzene; Drug

1985