dinitrochlorobenzene has been researched along with Edema in 13 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mouse ear edema was induced by topical application of arachidonic acid." | 3.76 | Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity. ( Cheon, HG; Cho, YS; Kang, NS; Kim, CH; Surh, JH; Yoo, SE, 2010) |
| " KR-33749 showed in vivo protective effects against arachidonic acid-induced ear edema and DNCB-induced atopic dermatitis-like symptoms in NC/Nga mice." | 3.76 | Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity. ( Cheon, HG; Cho, YS; Kang, NS; Kim, CH; Surh, JH; Yoo, SE, 2010) |
| "In order to develop novel compounds for topical use possessing antiallergic as well as antiinflammatory activities, a series of o-aminophenol derivatives bearing H1-antihistaminic structures were synthesized and their effects were investigated on lipid peroxidation in rat brain homogenates, antiinflammatory effection arachidonic acid- and 12-O-tetradecanoylphorbol-13- acetate-induced mouse ear edema and antiallergic effect on 48-h homologous passive cutaneous anaphylaxis in rats." | 3.69 | Synthesis and topical antiinflammatory and antiallergic activities of antioxidant o-aminophenol derivatives. ( Akahoshi, F; Fukaya, C; Kajii, M; Kuwahara, S; Sakaue, Y; Sugiura, M; Sugiyama, N; Yakumaru, H, 1994) |
| " The colon scores in SWP groups in rats was obviously lower than those in the control and similarly the serum levels of NO in the treatment groups were significantly lower than that of control group except for low dosage group of SWP." | 1.37 | Treatment of Suqingwan watered pill reduces colon injury induced by experimental colitis. ( Han, N; Jiang, S; Kang, R; Li, G; Li, Q; Liu, Z; Yin, J, 2011) |
| "Mouse ear edema was induced by topical application of arachidonic acid." | 1.36 | Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity. ( Cheon, HG; Cho, YS; Kang, NS; Kim, CH; Surh, JH; Yoo, SE, 2010) |
| " A complete dose-response curve was developed for DNFB and the dose which sensitized half the mice in a group (SD50, 0." | 1.28 | The noninvasive mouse ear swelling assay. I. Refinements for detecting weak contact sensitizers. ( Guiney, PD; Hawk, C; Kaliszewski, SD; Thorne, PS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sugiyama, N | 1 |
| Akahoshi, F | 1 |
| Kuwahara, S | 1 |
| Kajii, M | 1 |
| Sakaue, Y | 1 |
| Yakumaru, H | 1 |
| Sugiura, M | 1 |
| Fukaya, C | 1 |
| Cho, YS | 1 |
| Kim, CH | 1 |
| Surh, JH | 1 |
| Kang, NS | 1 |
| Yoo, SE | 1 |
| Cheon, HG | 1 |
| Han, N | 1 |
| Li, G | 1 |
| Kang, R | 1 |
| Li, Q | 1 |
| Liu, Z | 1 |
| Jiang, S | 1 |
| Yin, J | 1 |
| Ju, C | 1 |
| McCoy, JP | 1 |
| Chung, CJ | 1 |
| Graf, ML | 1 |
| Pohl, LR | 1 |
| Quintanar-Stephano, A | 1 |
| Kovacs, K | 1 |
| Berczi, I | 1 |
| Skoog, ML | 1 |
| Groth, O | 1 |
| Garrigue, JL | 1 |
| Nicolas, JF | 1 |
| Fraginals, R | 1 |
| Benezra, C | 1 |
| Bour, H | 1 |
| Schmitt, D | 1 |
| Holliday, MR | 1 |
| Corsini, E | 1 |
| Smith, S | 1 |
| Basketter, DA | 1 |
| Dearman, RJ | 1 |
| Kimber, I | 1 |
| Exton, MS | 1 |
| Elfers, A | 1 |
| Jeong, WY | 1 |
| Bull, DF | 1 |
| Westermann, J | 1 |
| Schedlowski, M | 1 |
| Kataranovski, M | 1 |
| Drasković-Pavlović, B | 1 |
| Jovcić, G | 1 |
| Milojević, G | 1 |
| Todorović, V | 1 |
| Colić, M | 1 |
| Popović, P | 1 |
| Bang, BG | 1 |
| Mahalanabis, D | 1 |
| Mukherjee, KL | 1 |
| Bang, FB | 1 |
| Krawiec, DR | 1 |
| Gaafar, SM | 1 |
| Thorne, PS | 1 |
| Hawk, C | 1 |
| Kaliszewski, SD | 1 |
| Guiney, PD | 1 |
13 other studies available for dinitrochlorobenzene and Edema
| Article | Year |
|---|---|
Synthesis and topical antiinflammatory and antiallergic activities of antioxidant o-aminophenol derivatives.
Topics: Administration, Topical; Aminophenols; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidant | 1994 |
Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cel | 2010 |
Treatment of Suqingwan watered pill reduces colon injury induced by experimental colitis.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Colitis, Ulcerative; Colon; Dextran Sulfate; Dinitro | 2011 |
Tolerogenic role of Kupffer cells in allergic reactions.
Topics: 2,4-Dinitrophenol; Animals; Cattle; Dendritic Cells; Dinitrochlorobenzene; Dinitrophenols; Drug Hype | 2003 |
Effects of neurointermediate pituitary lobectomy on humoral and cell-mediated immune responses in the rat.
Topics: Animals; Antibody Formation; Dermatitis, Contact; Dinitrochlorobenzene; Drinking; Ear, External; Ede | 2004 |
The cellular infiltrate in experimental allergic and toxic contact dermatitis. Effect of systemically administered corticosteroids.
Topics: Acanthosis Nigricans; Adrenal Cortex Hormones; Animals; Dermatitis, Contact; Dinitrochlorobenzene; E | 1981 |
Optimization of the mouse ear swelling test for in vivo and in vitro studies of weak contact sensitizers.
Topics: Animals; Cell Division; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Ear, External; Edema; Eu | 1994 |
Differential induction of cutaneous TNF-alpha and IL-6 by topically applied chemicals.
Topics: Adjuvants, Immunologic; Administration, Cutaneous; Allergens; Animals; Benzalkonium Compounds; Cytok | 1997 |
Conditioned suppression of contact sensitivity is independent of sympathetic splenic innervation.
Topics: Animals; Conditioning, Classical; Cyclosporine; Denervation; Dermatitis, Contact; Dinitrochlorobenze | 2000 |
Peripheral blood granulocyte activity following contact sensitization of rats with dinitrochlorobenzene.
Topics: Animals; Antibodies, Monoclonal; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Survival; Dermati | 2001 |
T and B lymphocyte rosetting in undernourished children.
Topics: B-Lymphocytes; Child, Preschool; Dinitrochlorobenzene; Edema; Humans; Immune Adherence Reaction; Inf | 1975 |
A comparative study of allergic and primary irritant contact dermatitis with dinitrochlorobenzene (DNCB) in dogs.
Topics: Administration, Topical; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Dogs; Drug Hypersensiti | 1975 |
The noninvasive mouse ear swelling assay. I. Refinements for detecting weak contact sensitizers.
Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Dinitrofluorobenzene; Ear, External; Edema; Hype | 1991 |