Page last updated: 2024-10-15

dinitrochlorobenzene and Dermatoses

dinitrochlorobenzene has been researched along with Dermatoses in 33 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Research Excerpts

ExcerptRelevanceReference
"16 patients with cutaneous sarcoidosis were treated intermittently over a period of 6 months with levamisole in an open study."9.04Cutaneous sarcoidosis treated with levamisole. ( Veien, NK, 1977)
"A study using daily topical applications of dinitrochlorobenzene on recalcitrant verrucae vulgares demonstrated this to be of practical value."7.66Immunotherapy of verrucae vulgares with dinitrochlorobenzene. ( Buckner, D; Price, NM, 1978)
"16 patients with cutaneous sarcoidosis were treated intermittently over a period of 6 months with levamisole in an open study."5.04Cutaneous sarcoidosis treated with levamisole. ( Veien, NK, 1977)
" Mouse ear edema was induced by topical application of arachidonic acid."3.76Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity. ( Cheon, HG; Cho, YS; Kang, NS; Kim, CH; Surh, JH; Yoo, SE, 2010)
" KR-33749 showed in vivo protective effects against arachidonic acid-induced ear edema and DNCB-induced atopic dermatitis-like symptoms in NC/Nga mice."3.76Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity. ( Cheon, HG; Cho, YS; Kang, NS; Kim, CH; Surh, JH; Yoo, SE, 2010)
" Obligate contact sensitizers such as diphencyprone or dinitrochlorobenzene have been used against viral and autoimmune diseases."3.72[Topical immunomodulators in dermatology]. ( Hengge, UR; Meykadeh, N, 2003)
" Vitamin A acid and benzoyl peroxide have brought significant advances in the topical treatment of acne."3.66[Advances in topical therapy of skin diseases (author's transl)]. ( Happle, R, 1979)
"A study using daily topical applications of dinitrochlorobenzene on recalcitrant verrucae vulgares demonstrated this to be of practical value."3.66Immunotherapy of verrucae vulgares with dinitrochlorobenzene. ( Buckner, D; Price, NM, 1978)
"Mouse ear edema was induced by topical application of arachidonic acid."1.36Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity. ( Cheon, HG; Cho, YS; Kang, NS; Kim, CH; Surh, JH; Yoo, SE, 2010)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199020 (60.61)18.7374
1990's1 (3.03)18.2507
2000's1 (3.03)29.6817
2010's3 (9.09)24.3611
2020's8 (24.24)2.80

Authors

AuthorsStudies
Zhang, Y2
Du, W1
Zhu, D1
Li, M2
Qu, L1
Rao, G1
Lin, Y1
Tong, X1
Sun, Y1
Huang, F1
Fan, M1
Wedamulla, NE1
Choi, YJ1
Zhang, Q2
Bae, SM1
Kim, EK1
Liu, J1
Tao, Y1
Zou, X1
Liu, Q1
Meng, X1
Su, J1
Tang, Y1
Su, Y1
Du, Y1
Wu, X1
Chen, X1
Song, Y1
Lai, L1
Cheng, H1
Yang, L1
Yang, Y1
Wang, Q1
Fan, P1
Xie, S1
Zhang, Z1
Yuan, Q1
He, J1
Zhang, J1
Liu, X2
Xu, L1
Voss, GT1
Gularte, MS1
de Oliveira, RL1
Luchese, C1
Fajardo, AR1
Wilhelm, EA1
Yeo, H1
Lee, YH1
Ahn, SS1
Jung, E1
Lim, Y1
Shin, SY1
Bak, DH1
Lee, E1
Lee, BC1
Choi, MJ1
Kwon, TR1
Hong, J1
Mun, SK1
Lee, K1
Kim, S1
Na, J1
Kim, BJ1
Yang, JH1
Yoo, JM1
Cho, WK1
Ma, JY1
Cho, YS1
Kim, CH1
Surh, JH1
Kang, NS1
Yoo, SE1
Cheon, HG1
Meykadeh, N1
Hengge, UR1
GOLAY, M1
BRUN, R1
Johansson, E1
Förström, L1
Thiers, BH1
Fulton, RA1
Souteyrand, P1
Thivolet, J1
Lahti, A1
Hannuksela, M1
Niwa, Y1
Niwa, H1
Kohmura, J1
Ou, DW1
Yokoyama, MM1
Skoog, ML1
Groth, O1
Fedotov, VP1
Lesnitskiĭ, AI1
Logunov, VP1
Manuĭlova, LA1
Zheliaz, EV1
Djawari, D1
Körner, E1
Haneke, E2
Hilditch-Maguire, PA1
Lieppe, DM1
West, D1
Lambert, PF1
Frazer, IH1
Happle, R1
Veien, NK2
Nater, JP1
Baar, AJ1
Bleumink, E1
Gutschmidt, E1
Buckner, D1
Price, NM1
Gliński, W1
Jablonska, S1
Langner, A1
Obalek, S1
Haftek, M1
Proniewska, M1
Bender, ME1
Nakagawa, S1
Takei, Y1
Bang, D1
Jinno, Y1
Ueki, H1
Stahl, D1
Brodthagen, H1
Dunagin, WG1
Wilkin, JK1
Wilkerson, MG1

Reviews

1 review available for dinitrochlorobenzene and Dermatoses

ArticleYear
Hazards of therapy.
    Journal of the American Academy of Dermatology, 1981, Volume: 4, Issue:4

    Topics: Dinitrochlorobenzene; Hexachlorocyclohexane; Humans; Liver Cirrhosis; Methotrexate; Minocycline; Pho

1981

Trials

1 trial available for dinitrochlorobenzene and Dermatoses

ArticleYear
Cutaneous sarcoidosis treated with levamisole.
    Dermatologica, 1977, Volume: 154, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Dinitrochlorobenzene; Drug Evaluation; Female; Humans; Levami

1977

Other Studies

31 other studies available for dinitrochlorobenzene and Dermatoses

ArticleYear
Vasicine alleviates 2,4-dinitrochlorobenzene-induced atopic dermatitis and passive cutaneous anaphylaxis in BALB/c mice.
    Clinical immunology (Orlando, Fla.), 2022, Volume: 244

    Topics: Alkaloids; Animals; Anti-Allergic Agents; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Immun

2022
    Nutrients, 2022, Dec-24, Volume: 15, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cytokines; Dermatitis, Atopic; Dinitrobenzenes; Dinit

2022
In vitro and in vivo exploration of the anti-atopic dermatitis mechanism of action of Tibetan medicine Qi-Sai-Er-Sang-Dang-Song decoction.
    Journal of ethnopharmacology, 2023, Apr-24, Volume: 306

    Topics: Animals; Anti-Inflammatory Agents; Dermatitis, Atopic; Dinitrochlorobenzene; Drugs, Chinese Herbal;

2023
Integrated transcriptomic and metabolomic analyses of DNCB-induced atopic dermatitis in mice.
    Life sciences, 2023, Mar-15, Volume: 317

    Topics: Animals; Cytokines; Dermatitis, Atopic; Dinitrobenzenes; Dinitrochlorobenzene; Mice; Mice, Inbred BA

2023
PYR-41, an inhibitor of ubiquitin-activating enzyme E1, attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:10

    Topics: Animals; Dermatitis, Atopic; Dinitrochlorobenzene; Mice; NF-kappa B; Skin Diseases; Tumor Necrosis F

2023
Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation.
    Journal of ethnopharmacology, 2024, Jan-30, Volume: 319, Issue:Pt 2

    Topics: Animals; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Ethanol; Gels; Inflammation; Mice; Mic

2024
Biopolymeric films as delivery vehicles for controlled release of hydrocortisone: Promising devices to treat chronic skin diseases.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 114

    Topics: Animals; Delayed-Action Preparations; Dinitrochlorobenzene; Humans; Hydrocortisone; Mice; Mice, Inbr

2020
Chrysin Inhibits TNFα-Induced TSLP Expression through Downregulation of EGR1 Expression in Keratinocytes.
    International journal of molecular sciences, 2021, Apr-21, Volume: 22, Issue:9

    Topics: Animals; Cells, Cultured; Cytokines; Dinitrochlorobenzene; Early Growth Response Protein 1; Flavonoi

2021
Therapeutic potential of topically administered γ-AlOOH on 2,4-dinitrochlorobenzene-induced atopic dermatitis-like lesions in Balb/c mice.
    Experimental dermatology, 2019, Volume: 28, Issue:2

    Topics: Administration, Topical; Aluminum Hydroxide; Aluminum Oxide; Animals; Anti-Inflammatory Agents; Cell

2019
Ethanol Extract of Sanguisorbae Radix Inhibits Mast Cell Degranulation and Suppresses 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Animals; Cells, Cultured; Dermatitis, Atopic; Dinitrochlorobenzene; Ethanol; Male; Mast Cells; Mice;

2016
Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity.
    Pharmacology, 2010, Volume: 86, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cel

2010
[Topical immunomodulators in dermatology].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2003, Volume: 54, Issue:7

    Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Aged; Aged, 80 and over; Aminoquinolines; As

2003
[Experimental eczema. VI. Eczema & acanthosis induced in the guinea pig by repeated administration of dinitrochlorobenzene].
    Dermatologica, 1958, Volume: 116, Issue:6

    Topics: Dinitrochlorobenzene; Eczema; Guinea Pigs; Nitrobenzenes; Skin Diseases

1958
Dinitrochlorbenzene (DNCB) treatment of viral warts. A 5-year follow-up study.
    Acta dermato-venereologica, 1984, Volume: 64, Issue:6

    Topics: Adolescent; Adult; Aged; Dinitrochlorobenzene; Female; Follow-Up Studies; Humans; Immunity, Cellular

1984
Influence of retinoid Ro 10-9359 on cell-mediated immunity in vivo.
    Dermatologica, 1982, Volume: 165, Issue:6

    Topics: Dinitrochlorobenzene; Etretinate; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Imm

1982
Topical immunotherapy with tuberculin jelly for common warts.
    Archives of dermatological research, 1982, Volume: 273, Issue:1-2

    Topics: Administration, Topical; Adult; Dinitrochlorobenzene; Humans; Immunotherapy; Skin Diseases; Tubercul

1982
Studies on the dinitrochlorobenzene (DNCB) sensitization test.
    Annals of allergy, 1982, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Dinitrochlorobenzene; Female; Glucocorticoids; Humans; Lymphocyte Ac

1982
The cellular infiltrate in experimental allergic and toxic contact dermatitis. Effect of systemically administered corticosteroids.
    International archives of allergy and applied immunology, 1981, Volume: 65, Issue:2

    Topics: Acanthosis Nigricans; Adrenal Cortex Hormones; Animals; Dermatitis, Contact; Dinitrochlorobenzene; E

1981
[2,4-dinitrochlorobenzene skin test as an index of the primary cellular immunological response in skin diseases and syphilis].
    Vestnik dermatologii i venerologii, 1981, Issue:10

    Topics: Adult; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Male; Mi

1981
[Cross allergies following sensitization with dinitrochlorbenzol (DNCB)].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1980, Volume: 31, Issue:4

    Topics: Cross Reactions; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Immunotherapy; Melanoma; N

1980
T cell-mediated and non-specific inflammatory mechanisms contribute to the skin pathology of HPV 16 E6E7 transgenic mice.
    Intervirology, 1999, Volume: 42, Issue:1

    Topics: Age Factors; Animals; Cyclosporine; Dinitrochlorobenzene; Female; Humans; Hyperplasia; Immunity, Cel

1999
[Advances in topical therapy of skin diseases (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1979, Jan-26, Volume: 121, Issue:4

    Topics: Acne Vulgaris; Administration, Topical; Alopecia; Benzoyl Peroxide; Dinitrochlorobenzene; Fluocortol

1979
[The treatment of common warts with 2,4-dinitrochlorobenzene (DNCB)].
    Nederlands tijdschrift voor geneeskunde, 1979, Mar-14, Volume: 123, Issue:15

    Topics: Administration, Topical; Adult; Aged; Chronic Disease; Dinitrochlorobenzene; Female; Foot Diseases;

1979
Premature multiple Bowen's disease in poikiloderma congenitale with warty hyperkeratoses.
    Dermatologica, 1979, Volume: 158, Issue:5

    Topics: Administration, Topical; Adolescent; Bowen's Disease; Carcinoma, Squamous Cell; Dinitrochlorobenzene

1979
Immunotherapy of verrucae vulgares with dinitrochlorobenzene.
    The British journal of dermatology, 1978, Volume: 98, Issue:4

    Topics: Adolescent; Adult; Dermatitis, Contact; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Im

1978
Cell-mediated immunity in epidermodysplasia verruciformis.
    Dermatologica, 1976, Volume: 153, Issue:4

    Topics: Adolescent; Adult; Child; Concanavalin A; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular;

1976
Concepts of wart regression.
    Archives of dermatology, 1986, Volume: 122, Issue:6

    Topics: Dinitrochlorobenzene; Humans; Immunity, Cellular; Immunotherapy; Macrophages; Papillomaviridae; Remi

1986
Histological study on the fate of haptenated epidermal cells injected intradermally in guinea pigs.
    Archives of dermatological research, 1987, Volume: 279 Suppl

    Topics: Animals; Dinitrobenzenes; Dinitrochlorobenzene; Epidermis; Guinea Pigs; Haptens; Hypersensitivity, D

1987
Cutaneous sarcoidosis in Caucasians.
    Journal of the American Academy of Dermatology, 1987, Volume: 16, Issue:3 Pt 1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Child; Child, Preschool; Dinitrochlorobenze

1987
Potential hazards of dinitrochlorobenzene (DNCB) disputed.
    Archives of dermatology, 1986, Volume: 122, Issue:1

    Topics: Animals; Carcinogens; Cricetinae; Dinitrochlorobenzene; Humans; Mesocricetus; Mice; Mutagenicity Tes

1986
Motives and dinitrochlorobenzene.
    Archives of dermatology, 1986, Volume: 122, Issue:1

    Topics: Carcinogens; Dinitrochlorobenzene; Drug Contamination; Humans; Mutagens; Nitrobenzenes; Skin Disease

1986