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dinitrochlorobenzene and Dermatitis

dinitrochlorobenzene has been researched along with Dermatitis in 18 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Dermatitis: Any inflammation of the skin.

Research Excerpts

ExcerptRelevanceReference
"Our findings suggest that pamoic acid activation of peripheral GPR35 can contribute to the improvement of pruritus and its associated diseases."8.31Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)
"Pruritic dermatitis is a disease with a considerable unmet need for treatment and appears to present with not only epidermal but also peripheral neuronal complications."5.91Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)
"Our findings suggest that pamoic acid activation of peripheral GPR35 can contribute to the improvement of pruritus and its associated diseases."4.31Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)
"2, 4-dinitrofluorobenzene (DNFB) and 2, 4-dinitrochlorobenzene (DNCB) are well known as skin sensitizers that can cause dermatitis."4.12Selective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB. ( Niu, C; Qu, Y; Sun, X; Wang, K; Wu, H, 2022)
"We examined the time-dependent dynamics of epidermal Langerhans' cells (LC) in human systemic lupus erythematosus (SLE), in MRL/Mp-lpr/lpr(MRL/lpr) mice, and in various experimental cutaneous inflammations, such as the Arthus reaction, dinitrochlorobenzene allergic dermatitis, and croton oil primary irritant dermatitis, in order to clarify the pathomechanisms of lupus skin lesions."3.67Evaluation of ATPase-positive Langerhans' cells in skin lesions of lupus erythematosus and experimentally induced inflammations. ( Furukawa, F; Imamura, S; Kanauchi, H, 1989)
"Pruritic dermatitis is a disease with a considerable unmet need for treatment and appears to present with not only epidermal but also peripheral neuronal complications."1.91Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis. ( Hwang, SW; Kim, C; Kim, M; Kim, Y; Lim, JY; Zheng, H, 2023)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199012 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (22.22)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Wu, H1
Niu, C1
Qu, Y1
Sun, X1
Wang, K1
Kim, C1
Kim, Y1
Lim, JY1
Kim, M2
Zheng, H1
Hwang, SW1
Tran, le S1
Mittal, D1
Mattarollo, SR1
Frazer, IH1
Schüttenhelm, BN1
Duraku, LS1
Dijkstra, JF1
Walbeehm, ET1
Holstege, JC1
Jeong Ryu, S1
Ju, JM1
Kim, W1
Bum Kim, M1
Hee Oh, K1
Sup Lee, D1
Lee, H1
Eun Oh, J1
Soo Park, K1
Young Choi, E1
von Bonin, A1
Rausch, A1
Mengel, A1
Hitchcock, M1
Krüger, M1
von Ahsen, O1
Merz, C1
Röse, L1
Stock, C1
Martin, SF1
Leder, G1
Döcke, WD1
Asadullah, K1
Zügel, U1
ZELIGMAN, I1
EISEN, HN1
TABACHNICK, M1
HUNZIKER, N1
MAIBACH, HI1
MAGUIRE, HC1
ROSENBERG, EW1
FISCHER, RW1
FREY, JR3
DE WECK, AL1
GELEICK, H3
DEWECK, AL2
GROTH, O1
Meinhof, W1
Takasu, H1
Kanauchi, H1
Furukawa, F1
Imamura, S1

Other Studies

18 other studies available for dinitrochlorobenzene and Dermatitis

ArticleYear
Selective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:2

    Topics: Dermatitis; Dinitrochlorobenzene; Dinitrofluorobenzene; Humans; Molecular Docking Simulation; Skin;

2022
Pamoic acid-induced peripheral GPR35 activation improves pruritus and dermatitis.
    British journal of pharmacology, 2023, Volume: 180, Issue:23

    Topics: Animals; Dermatitis; Dinitrochlorobenzene; Ganglia, Spinal; Pruritus; Skin

2023
Interleukin-17A Promotes Arginase-1 Production and 2,4-Dinitrochlorobenzene-Induced Acute Hyperinflammation in Human Papillomavirus E7 Oncoprotein-Expressing Skin.
    Journal of innate immunity, 2015, Volume: 7, Issue:4

    Topics: Animals; Arginase; Dermatitis; Dinitrochlorobenzene; Gene Expression Regulation, Enzymologic; Humans

2015
Differential Changes in the Peptidergic and the Non-Peptidergic Skin Innervation in Rat Models for Inflammation, Dry Skin Itch, and Dermatitis.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:8

    Topics: Acetone; Animals; Biopsy; Calcitonin Gene-Related Peptide; Dermatitis; Dinitrochlorobenzene; Disease

2015
Alleviation of skin inflammation after Lin(-) cell transplantation correlates with their differentiation into myeloid-derived suppressor cells.
    Scientific reports, 2015, Oct-06, Volume: 5

    Topics: Animals; Blotting, Western; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Dermatitis; Di

2015
Inhibition of the IL-2-inducible tyrosine kinase (Itk) activity: a new concept for the therapy of inflammatory skin diseases.
    Experimental dermatology, 2011, Volume: 20, Issue:1

    Topics: Animals; Base Sequence; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dinitrochlorob

2011
Experimental contact dermatitis. I. Dinitrochlorobenzene contact dermatitis in guinea pigs.
    The Journal of investigative dermatology, 1954, Volume: 22, Issue:2

    Topics: Animals; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; Guinea Pigs; Nitrobenzenes

1954
Elicitation of allergic contact dermatitis in the guinea pig; the distribution of bound dinitrobenzene groups within the skin and quantitative determination of the extent of combination of 2,4-dinitro-chlorobenzene with epidermal protein in vivo.
    The Journal of experimental medicine, 1958, Dec-01, Volume: 108, Issue:6

    Topics: Animals; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Contact; Dinitrobenzenes; Dinitrochlo

1958
[Some remarks on desensitization in experimental eczema induced in guinea pigs with dinitrochlorobenzene].
    Dermatologica, 1963, Volume: 126

    Topics: Animals; Antigen-Antibody Reactions; Dermatitis; Dermatitis, Contact; Desensitization, Immunologic;

1963
ELICITATION OF DELAYED HYPERSENSITIVITY (DNCB CONTACT DERMATITIS) IN MARKEDLY PANLEUKOPENIC GUINEA PIGS.
    The Journal of investigative dermatology, 1963, Volume: 41

    Topics: Animals; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; Guinea Pigs; Hypersensitivity, Delay

1963
DNCB ALLERGY IN THE GUINEA PIG COLON.
    Archives of dermatology, 1964, Volume: 89

    Topics: Animals; Colonic Diseases; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; Dinitrophenols; Gu

1964
IMMUNOLOGICAL UNRESPONSIVENESS IN ALLERGIC CONTACT DEMATITIS TO DINITROCHLOROBENZENE IN GUINEA PIGS.
    The Journal of investigative dermatology, 1964, Volume: 42

    Topics: Animals; Antigen-Antibody Reactions; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; Guinea P

1964
SPECIFIC INHIBITION OF CONTACT DERMATITIS TO DINITROCHLOROBENZENE IN GUINEA PIGS BY INJECTION OF HAPTENS AND PROTEIN CONJUGATES.
    International archives of allergy and applied immunology, 1964, Volume: 24

    Topics: Aniline Compounds; Animals; Antigens; Cysteine; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzen

1964
INHIBITION OF THE CONTACT REACTION TO DINITROCHLOROBENZENE BY INTRAVENOUS INJECTION OF DINITROBENZENE SULFONATE IN GUINEA PIGS SENSITIZED TO DINITROCHLOROBENZENE.
    The Journal of investigative dermatology, 1964, Volume: 42

    Topics: Animals; Dermatitis; Dermatitis, Contact; Dinitrobenzenes; Dinitrochlorobenzene; Erythema; Freund's

1964
STUDIES ON CONTACT SKIN REACTIONS AND NORMAL SKIN OF PASSIVELY SENSITIZED GUINEA-PIGS. I. A HISTOLOGICAL STUDY OF TEST LESIONS IN RECIPIENTS AFTER PASSIVE TRANSFER OF DINITROCHLOROBENZENE (DNCB) HYPERSENSITIVITY WITH LYMPHOID CELLS.
    Acta Societatis Medicorum Upsaliensis, 1963, Volume: 68

    Topics: Animals; Autoradiography; Dermatitis; Dermatitis, Contact; Dinitrochlorobenzene; DNA; Guinea Pigs; H

1963
[Pathophysiology and therapy of skin diseases].
    MMW, Munchener medizinische Wochenschrift, 1979, Jan-26, Volume: 121, Issue:4

    Topics: Acne Vulgaris; Alopecia Areata; Androgen Antagonists; Collagen Diseases; Dermatitis; Dermatitis, Ato

1979
Inflammation of the skin. I. Phospholipid metabolism in some experimental inflammations of mouse skin.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:1

    Topics: Animals; Croton Oil; Dermatitis; Dinitrochlorobenzene; Male; Mice; Phospholipids; Phosphorus Radiois

1975
Evaluation of ATPase-positive Langerhans' cells in skin lesions of lupus erythematosus and experimentally induced inflammations.
    Archives of dermatological research, 1989, Volume: 281, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Arthus Reaction; Croton Oil; Dermatitis; Dermatitis, Contact; Di

1989