dinitrochlorobenzene has been researched along with Crohn Disease in 8 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among 53 patients with documented Crohn's disease, 30% manifested a defect in delayed hypersensitivity demonstrated by negative DNCB skin tests and significant (p less than 0." | 2.65 | BCG treatment of Crohn's disease. ( Conley, DR; Marks, JW; Opelz, G; Panish, JF; Rahban, S; Schoenfield, LJ; Sherman, JH; Terasaki, PI, 1979) |
| "Five patients with Crohn's disease proved constantly decreased total absolute lymphocyte counts in peripheral blood." | 1.26 | [The immune competence of patients with Crohn's disease (author's transl)]. ( Bürkle, PA; Federlin, K; Schäfer, B; Tönnesmann, E, 1979) |
| "Immunosuppressed patients with Crohn's disease did not develop sensitivity to dinitrochlorobenzene and had mildly depressed skin test reactivity to common skin test procedures." | 1.26 | Immunological studies in patients with Crohn's disease. ( Albertini, RJ; Beeken, WL; MacPherson, BR, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rabin, BS | 1 |
| Rahban, S | 1 |
| Sherman, JH | 1 |
| Opelz, G | 1 |
| Conley, DR | 1 |
| Panish, JF | 1 |
| Marks, JW | 1 |
| Terasaki, PI | 1 |
| Schoenfield, LJ | 1 |
| Tönnesmann, E | 1 |
| Bürkle, PA | 1 |
| Schäfer, B | 1 |
| Federlin, K | 1 |
| Meyers, S | 3 |
| Sachar, DB | 2 |
| Taub, RN | 3 |
| Janowitz, HD | 3 |
| Ramachandar, K | 1 |
| Forman, SP | 1 |
| Douglas, SD | 1 |
| Sacher, DB | 1 |
| MacPherson, BR | 1 |
| Albertini, RJ | 1 |
| Beeken, WL | 1 |
| Strober, W | 1 |
1 review available for dinitrochlorobenzene and Crohn Disease
| Article | Year |
|---|---|
Animal models of inflammatory bowel disease--an overview.
Topics: Animals; B-Lymphocytes; Carrageenan; Colitis; Crohn Disease; Dinitrochlorobenzene; Disease Models, A | 1985 |
1 trial available for dinitrochlorobenzene and Crohn Disease
| Article | Year |
|---|---|
BCG treatment of Crohn's disease.
Topics: Adolescent; Adult; Aged; BCG Vaccine; Clinical Trials as Topic; Crohn Disease; Dinitrochlorobenzene; | 1979 |
6 other studies available for dinitrochlorobenzene and Crohn Disease
| Article | Year |
|---|---|
Animal model: immunologic model of inflammatory bowel disease.
Topics: Animals; Antigens; Colitis, Ulcerative; Colon; Crohn Disease; Dinitrochlorobenzene; Disease Models, | 1980 |
[The immune competence of patients with Crohn's disease (author's transl)].
Topics: Adolescent; Adult; Antibodies; Crohn Disease; Dinitrochlorobenzene; Female; Hemocyanins; Humans; Imm | 1979 |
Significance of anergy to dinitrochlorobenzene (DNCB) in inflammatory bowel disease: family and postoperative studies.
Topics: Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Male; | 1978 |
T and B lymphocytes and cutaneous anergy in inflammatory bowel disease.
Topics: Azathioprine; B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hyper | 1976 |
Anergy to dinitrochlorobenzene and depression of T-lymphocytes in Crohn's disease and ulcerative colitis.
Topics: Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Leukocy | 1976 |
Immunological studies in patients with Crohn's disease.
Topics: Adolescent; Adult; Aged; Crohn Disease; Dinitrochlorobenzene; Female; Humans; Immunoglobulins; Immun | 1976 |