dinitrochlorobenzene has been researched along with Colitis Gravis in 15 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using 2,4-dinitrochlorobenzene combined with acetic acid to induce chronic ulcerative colitis (chronic UC) in rats." | 1.62 | Study on the effect of the treatment of Periplaneta americana L. extract Ento-B by Dinitrochlorobenzene combined with acetic acid induced UC in rats. ( He, M; Hilola, A; Liu, H; Liu, SS; Xu, YS; Zhang, CG; Zhou, N, 2021) |
| "PAE can protect against ulcerative colitis and this protection is attributed to anti-inflammation and fibroblasts viability." | 1.43 | Protective effect of Periplaneta americana extract in ulcerative colitis rats induced by dinitrochlorobenzene and acetic acid. ( Chen, J; Huang, L; Jin, J; Li, N; Lu, R; Lu, Y; Yu, Y; Zhang, L, 2016) |
| " The colon scores in SWP groups in rats was obviously lower than those in the control and similarly the serum levels of NO in the treatment groups were significantly lower than that of control group except for low dosage group of SWP." | 1.37 | Treatment of Suqingwan watered pill reduces colon injury induced by experimental colitis. ( Han, N; Jiang, S; Kang, R; Li, G; Li, Q; Liu, Z; Yin, J, 2011) |
| "Curcumin treatment ameliorates colonic damage in DNCB induced colitic rats, an effect associated with an improvement in intestinal oxidative stress and downregulation of colonic NFkappa-B and iNOS expression." | 1.34 | NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS. ( Babu, UV; Gopumadhavan, S; Mitra, SK; Peer, G; Rafiq, M; Venkataranganna, MV, 2007) |
| "Ulcerative colitis was induced in male rats by sensitizing with topical application of DNCB in acetone for 14 d and intra-colonol challenge with DNCB on day 15." | 1.34 | NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS. ( Babu, UV; Gopumadhavan, S; Mitra, SK; Peer, G; Rafiq, M; Venkataranganna, MV, 2007) |
| "A model of ulcerative colitis related to cellular immunity has previously been produced by sensitization of the colon of guinea pigs with dinitrochlorobenzene (DNCB)." | 1.26 | A cell-mediated immune model of inflammatory bowel disease in the rabbit. ( Rabin, BS; Rogers, SJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, SS | 1 |
| Xu, YS | 1 |
| Hilola, A | 1 |
| Zhou, N | 1 |
| He, M | 1 |
| Zhang, CG | 1 |
| Liu, H | 1 |
| Li, N | 1 |
| Lu, R | 1 |
| Yu, Y | 1 |
| Lu, Y | 1 |
| Huang, L | 1 |
| Jin, J | 1 |
| Zhang, L | 1 |
| Chen, J | 1 |
| Han, N | 1 |
| Li, G | 1 |
| Kang, R | 1 |
| Li, Q | 1 |
| Liu, Z | 1 |
| Jiang, S | 1 |
| Yin, J | 1 |
| Venkataranganna, MV | 1 |
| Rafiq, M | 1 |
| Gopumadhavan, S | 1 |
| Peer, G | 1 |
| Babu, UV | 1 |
| Mitra, SK | 1 |
| Rabin, BS | 2 |
| Streilein, JW | 1 |
| Rogers, SJ | 1 |
| Meyers, S | 3 |
| Sachar, DB | 2 |
| Taub, RN | 3 |
| Janowitz, HD | 3 |
| Ramachandar, K | 1 |
| Forman, SP | 1 |
| Douglas, SD | 1 |
| Sacher, DB | 1 |
| Tomecki, R | 1 |
| Mack, DR | 1 |
| Lau, AS | 1 |
| Sherman, PM | 1 |
| Rózga, J | 1 |
| Boughton-Smith, NK | 1 |
| Whittle, BJ | 1 |
| Onderdonk, AB | 1 |
1 review available for dinitrochlorobenzene and Colitis Gravis
| Article | Year |
|---|---|
Ulcerative colitis in the experimental animal.
Topics: Animals; Carrageenan; Colitis, Ulcerative; Dinitrochlorobenzene; Fatty Acids; Oligopeptides; Oxidati | 1990 |
14 other studies available for dinitrochlorobenzene and Colitis Gravis
| Article | Year |
|---|---|
Study on the effect of the treatment of Periplaneta americana L. extract Ento-B by Dinitrochlorobenzene combined with acetic acid induced UC in rats.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Dinitrochlorobenzene; Periplaneta; Plant Extracts; | 2021 |
Protective effect of Periplaneta americana extract in ulcerative colitis rats induced by dinitrochlorobenzene and acetic acid.
Topics: Acetic Acid; Animals; Colitis, Ulcerative; Collagen; Complementary Therapies; Dinitrochlorobenzene; | 2016 |
Treatment of Suqingwan watered pill reduces colon injury induced by experimental colitis.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Colitis, Ulcerative; Colon; Dextran Sulfate; Dinitro | 2011 |
NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colon; | 2007 |
Animal model: immunologic model of inflammatory bowel disease.
Topics: Animals; Antigens; Colitis, Ulcerative; Colon; Crohn Disease; Dinitrochlorobenzene; Disease Models, | 1980 |
Inflammatory bowel disease: T lymphocytes may be the culprits.
Topics: Animals; Colitis, Ulcerative; Colon; Dinitrochlorobenzene; Humans; Inflammatory Bowel Diseases; Rabb | 1978 |
A cell-mediated immune model of inflammatory bowel disease in the rabbit.
Topics: Animals; Colitis, Ulcerative; Colon; Dinitrochlorobenzene; Hypersensitivity, Delayed; Immunity, Cell | 1978 |
Significance of anergy to dinitrochlorobenzene (DNCB) in inflammatory bowel disease: family and postoperative studies.
Topics: Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Male; | 1978 |
T and B lymphocytes and cutaneous anergy in inflammatory bowel disease.
Topics: Azathioprine; B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hyper | 1976 |
Anergy to dinitrochlorobenzene and depression of T-lymphocytes in Crohn's disease and ulcerative colitis.
Topics: Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Leukocy | 1976 |
[Contact allergy to 2,4-dinitrochlorobenzene in patients with ulcerative colitis (author's transl)].
Topics: Colitis, Ulcerative; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Male; Nitroben | 1975 |
Systemic tumor necrosis factor-alpha production in experimental colitis.
Topics: Animals; Benzopyrans; Cells, Cultured; Colitis, Ulcerative; Dinitrochlorobenzene; Disease Models, An | 1992 |
Increased metabolism of arachidonic acid in an immune model of colitis in guinea-pigs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic | 1985 |
Experimental models for ulcerative colitis.
Topics: Animals; Antibody Formation; Carrageenan; Colitis, Ulcerative; Dinitrochlorobenzene; Disease Models, | 1985 |