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dinitrochlorobenzene and Colitis Gravis

dinitrochlorobenzene has been researched along with Colitis Gravis in 15 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Research Excerpts

ExcerptRelevanceReference
"Using 2,4-dinitrochlorobenzene combined with acetic acid to induce chronic ulcerative colitis (chronic UC) in rats."1.62Study on the effect of the treatment of Periplaneta americana L. extract Ento-B by Dinitrochlorobenzene combined with acetic acid induced UC in rats. ( He, M; Hilola, A; Liu, H; Liu, SS; Xu, YS; Zhang, CG; Zhou, N, 2021)
"PAE can protect against ulcerative colitis and this protection is attributed to anti-inflammation and fibroblasts viability."1.43Protective effect of Periplaneta americana extract in ulcerative colitis rats induced by dinitrochlorobenzene and acetic acid. ( Chen, J; Huang, L; Jin, J; Li, N; Lu, R; Lu, Y; Yu, Y; Zhang, L, 2016)
" The colon scores in SWP groups in rats was obviously lower than those in the control and similarly the serum levels of NO in the treatment groups were significantly lower than that of control group except for low dosage group of SWP."1.37Treatment of Suqingwan watered pill reduces colon injury induced by experimental colitis. ( Han, N; Jiang, S; Kang, R; Li, G; Li, Q; Liu, Z; Yin, J, 2011)
"Curcumin treatment ameliorates colonic damage in DNCB induced colitic rats, an effect associated with an improvement in intestinal oxidative stress and downregulation of colonic NFkappa-B and iNOS expression."1.34NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS. ( Babu, UV; Gopumadhavan, S; Mitra, SK; Peer, G; Rafiq, M; Venkataranganna, MV, 2007)
"Ulcerative colitis was induced in male rats by sensitizing with topical application of DNCB in acetone for 14 d and intra-colonol challenge with DNCB on day 15."1.34NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS. ( Babu, UV; Gopumadhavan, S; Mitra, SK; Peer, G; Rafiq, M; Venkataranganna, MV, 2007)
"A model of ulcerative colitis related to cellular immunity has previously been produced by sensitization of the colon of guinea pigs with dinitrochlorobenzene (DNCB)."1.26A cell-mediated immune model of inflammatory bowel disease in the rabbit. ( Rabin, BS; Rogers, SJ, 1978)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Liu, SS1
Xu, YS1
Hilola, A1
Zhou, N1
He, M1
Zhang, CG1
Liu, H1
Li, N1
Lu, R1
Yu, Y1
Lu, Y1
Huang, L1
Jin, J1
Zhang, L1
Chen, J1
Han, N1
Li, G1
Kang, R1
Li, Q1
Liu, Z1
Jiang, S1
Yin, J1
Venkataranganna, MV1
Rafiq, M1
Gopumadhavan, S1
Peer, G1
Babu, UV1
Mitra, SK1
Rabin, BS2
Streilein, JW1
Rogers, SJ1
Meyers, S3
Sachar, DB2
Taub, RN3
Janowitz, HD3
Ramachandar, K1
Forman, SP1
Douglas, SD1
Sacher, DB1
Tomecki, R1
Mack, DR1
Lau, AS1
Sherman, PM1
Rózga, J1
Boughton-Smith, NK1
Whittle, BJ1
Onderdonk, AB1

Reviews

1 review available for dinitrochlorobenzene and Colitis Gravis

ArticleYear
Ulcerative colitis in the experimental animal.
    Acta physiologica Polonica, 1990, Volume: 41, Issue:4-6

    Topics: Animals; Carrageenan; Colitis, Ulcerative; Dinitrochlorobenzene; Fatty Acids; Oligopeptides; Oxidati

1990

Other Studies

14 other studies available for dinitrochlorobenzene and Colitis Gravis

ArticleYear
Study on the effect of the treatment of Periplaneta americana L. extract Ento-B by Dinitrochlorobenzene combined with acetic acid induced UC in rats.
    Acta cirurgica brasileira, 2021, Volume: 36, Issue:1

    Topics: Acetic Acid; Animals; Colitis, Ulcerative; Colon; Dinitrochlorobenzene; Periplaneta; Plant Extracts;

2021
Protective effect of Periplaneta americana extract in ulcerative colitis rats induced by dinitrochlorobenzene and acetic acid.
    Pharmaceutical biology, 2016, Volume: 54, Issue:11

    Topics: Acetic Acid; Animals; Colitis, Ulcerative; Collagen; Complementary Therapies; Dinitrochlorobenzene;

2016
Treatment of Suqingwan watered pill reduces colon injury induced by experimental colitis.
    Journal of ethnopharmacology, 2011, Jun-14, Volume: 136, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Colitis, Ulcerative; Colon; Dextran Sulfate; Dinitro

2011
NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS.
    World journal of gastroenterology, 2007, Feb-21, Volume: 13, Issue:7

    Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colon;

2007
Animal model: immunologic model of inflammatory bowel disease.
    The American journal of pathology, 1980, Volume: 99, Issue:1

    Topics: Animals; Antigens; Colitis, Ulcerative; Colon; Crohn Disease; Dinitrochlorobenzene; Disease Models,

1980
Inflammatory bowel disease: T lymphocytes may be the culprits.
    Gastroenterology, 1978, Volume: 75, Issue:1

    Topics: Animals; Colitis, Ulcerative; Colon; Dinitrochlorobenzene; Humans; Inflammatory Bowel Diseases; Rabb

1978
A cell-mediated immune model of inflammatory bowel disease in the rabbit.
    Gastroenterology, 1978, Volume: 75, Issue:1

    Topics: Animals; Colitis, Ulcerative; Colon; Dinitrochlorobenzene; Hypersensitivity, Delayed; Immunity, Cell

1978
Significance of anergy to dinitrochlorobenzene (DNCB) in inflammatory bowel disease: family and postoperative studies.
    Gut, 1978, Volume: 19, Issue:4

    Topics: Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Male;

1978
T and B lymphocytes and cutaneous anergy in inflammatory bowel disease.
    Annals of the New York Academy of Sciences, 1976, Volume: 278

    Topics: Azathioprine; B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hyper

1976
Anergy to dinitrochlorobenzene and depression of T-lymphocytes in Crohn's disease and ulcerative colitis.
    Gut, 1976, Volume: 17, Issue:11

    Topics: Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Leukocy

1976
[Contact allergy to 2,4-dinitrochlorobenzene in patients with ulcerative colitis (author's transl)].
    Przeglad lekarski, 1975, Volume: 32, Issue:7

    Topics: Colitis, Ulcerative; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Male; Nitroben

1975
Systemic tumor necrosis factor-alpha production in experimental colitis.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:11

    Topics: Animals; Benzopyrans; Cells, Cultured; Colitis, Ulcerative; Dinitrochlorobenzene; Disease Models, An

1992
Increased metabolism of arachidonic acid in an immune model of colitis in guinea-pigs.
    British journal of pharmacology, 1985, Volume: 86, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic

1985
Experimental models for ulcerative colitis.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:12 Suppl

    Topics: Animals; Antibody Formation; Carrageenan; Colitis, Ulcerative; Dinitrochlorobenzene; Disease Models,

1985