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dinitrochlorobenzene and Breast Neoplasms

dinitrochlorobenzene has been researched along with Breast Neoplasms in 37 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"The continuous administration of levamisole for immunological stimulation after breast cancer surgery increases life expectancy significantly."3.66[Immunotherapy of cancer using levamisole, immunologic control of the post-surgical patient and graphic follow-up]. ( de Carli, HO; Llargues, JM, 1980)
"Some preliminary results of using phenformin and miscleron in 17 breast cancer patients, previously radically operated upon, have been assessed as being characterized by metabolic disturbances associated with the reduced cell immunity level."3.66[Effect of fenformin and miscleron on the delayed hypersensitivity reaction in breast cancer patients]. ( Bershteĭn, LM; Buslaeva, VP; Kondrat'ev, VB; Ostroumova, MN; Semiglazov, VF, 1980)
" Delayed hypersensitivity was tested by dinitrochlorobenzene skin tests and responses to phytohemagglutinin."3.65Adrenalectomy and oophorectomy plus limited-term chemotherapy in the treatment of breast cancer. ( Asal, NR; Bottomley, RH; Hoge, AF; Shaw, MT, 1976)
"Delayed hypersensitivity to dinitrochlorobenzene (DNCB) was tested prior to radiation therapy in 206 patients with solid tumors."3.65Delayed hypersensitivity to DNCB and survival following radiation therapy in patients with solid malignant tumors. ( Hazra, TA; Inalsingh, A; Parks, LC; Peeples, W, 1975)
"Patients with Hodgkin's disease tend to have depressed responses to both newly encountered and recall antigens."2.35Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions. ( Burdick, JF; Herberman, RB; Wells, SA, 1975)
"Testing of delayed hypersensitivity responses to recall antigens, newly encountered antigens and tumor antigens has contributed to the understanding of several immunologic factors in human neoplasia."2.35Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions. ( Burdick, JF; Herberman, RB; Wells, SA, 1975)
"Patients with solid tumors are more likely to be deficient only in the response to newly encountered antigens."2.35Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions. ( Burdick, JF; Herberman, RB; Wells, SA, 1975)
"Derivatives of MCF7 breast carcinoma cells expressing GST P1-1 and MRP1 alone or in combination were developed."1.30Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1. ( Diah, SK; Morrow, CS; Smitherman, PK; Townsend, AJ, 1999)
"Patients with breast cancer, localized fibroadenomatosis and healthy females were examined for the initial state of cell immunity: the reaction of delayed hypersensitivity to DNCB, the absolute and relative amount of rosette forming cells (T-lymphocytes) and the stimulation of lymphocytes under exposure to PHA."1.26[Cellular immunity indices in benign breast tumors]. ( Baisheva, SA; Kaliev, IuSh; Mezinova, NN; Zhalgasbaeva, GT, 1980)
"The personal series consists of 140 cancer patients followed up over a period of some 3 years and submitted prior to the start of treatment to the DNCB skin test."1.26[The DNCB skin test and its comparison with the radioimmunological determination of CEA in some types of neoplasms]. ( Bianucci, P; De Rossi, O; Pastorino, G, 1979)
"Rapidly progressing breast cancer in Tunisia is not associated with an impairment of delayed hypersensitivity."1.26Rapidly progressing breast cancer (poussée évolutive) in Tunisia: studies on delayed hypersensitivity. ( Bahi, J; Belhassen, S; Bennaceur, M; Herberman, RB; Levine, PH; Mourali, N; Tabanne, F, 1978)
"Delayed hypersensitivity was tested by dinitrochlorobenzene skin tests and responses to phytohemagglutinin."1.26Adrenalectomy and oophorectomy plus limited-term chemotherapy in the treatment of breast cancer. ( Asal, NR; Bottomley, RH; Hoge, AF; Shaw, MT, 1976)
"Paradoxical findings in patients with breast cancer suggested a great complexity in the host tumour interaction."1.25Cellular immunity in cancer: comparison of delayed hypersensitivity skin tests in three common cancers. ( Bolton, PM; Davidson, JM; Hughes, LE; James, SL; Mander, AM; Newcombe, RG, 1975)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199034 (91.89)18.7374
1990's2 (5.41)18.2507
2000's0 (0.00)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oguztuzun, S1
Abu-Hijleh, A1
Coban, T1
Bulbul, D1
Kilic, M1
Iscan, M2
Cron, J1
Jansa, P1
Lee, YT1
Munzarová, M2
Kovarík, J2
Ninger, E1
Zemanová, D1
Lauerová, L2
Kolcová, V1
Hlávková, J2
Pacovský, Z1
de Carli, HO1
Llargues, JM1
Adler, A2
Stein, JA2
Ben-Efraim, S1
Baisheva, SA1
Zhalgasbaeva, GT1
Kaliev, IuSh1
Mezinova, NN1
Krown, SE1
Pinsky, CM2
Wanebo, HJ4
Braun, DW1
Wong, PP1
Oettgen, HF3
Bershteĭn, LM1
Buslaeva, VP1
Kondrat'ev, VB2
Ostroumova, MN1
Semiglazov, VF2
Mallon, E1
Powell, S1
Mortimer, P1
Ryan, TJ1
Diah, SK1
Smitherman, PK1
Townsend, AJ1
Morrow, CS1
Burdick, JF1
Wells, SA1
Herberman, RB2
Thaler, HT1
Hansen, JA1
Rosen, PP1
Robbins, GF1
Urban, JA1
Good, RA1
Klippel, KF1
Walz, HP1
Kreutz, G1
von Moltke, T1
Webster, DJ1
Richardson, G1
Baum, M1
Priestman, T1
Hughes, LE4
Bianucci, P2
Pastorino, G2
De Rossi, O2
Brondi, P1
Dutta, TK1
Sengputa, U1
Gupta, BD1
Beattie, EJ1
Mourali, N1
Levine, PH1
Tabanne, F1
Belhassen, S1
Bahi, J1
Bennaceur, M1
Mar'enko, AI1
L'vovich, EG1
Sofronov, BN1
Davies, CJ1
Meredith, ID1
Robins, RA1
Blamey, RW1
Baldwin, RW1
Nagar, R1
Maheshwari, HB1
Mukerjee, P1
Mittal, MM1
Schick, PM1
Shabot, MM1
Block, JB1
Rosenbloom, BE1
Burleigh, J1
Pilch, YH1
Klein, E1
Rosner, D1
Holtermann, OA1
Stoll, HL1
Song, SY1
Efraim, SB1
Maor, M1
Hoge, AF1
Bottomley, RH1
Shaw, MT1
Asal, NR1
Bolton, PM2
Mander, AM1
Davidson, JM1
James, SL1
Newcombe, RG3
Hazra, TA1
Parks, LC1
Inalsingh, A1
Peeples, W1
Cunningham, TJ1
Daut, D1
Wolfgang, PE1
Mellyn, M1
Maciolek, S1
Sponzo, RW1
Horton, J1
Jain, P1
Khanna, NN1
Shukla, HS2
Whitehead, RH2
Saha, K1
Madan, R1
Kapila, H1
Shinghal, RN1
Popelínský, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Establishment of an Inflammatory Breast Cancer Registry and Biospecimen Repository[NCT00340158]164 participants (Anticipated)Observational2003-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dinitrochlorobenzene and Breast Neoplasms

ArticleYear
Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions.
    Surgery, gynecology & obstetrics, 1975, Volume: 141, Issue:5

    Topics: Antigens; Antigens, Neoplasm; Arthus Reaction; Breast Neoplasms; Burkitt Lymphoma; Carcinoma; Coloni

1975
DNCB sensitivity in cancer patients. A review based on sequential testing in 430 patients.
    Clinical oncology, 1975, Volume: 1, Issue:1

    Topics: Adenocarcinoma; Adult; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Dinitrochlorob

1975

Trials

3 trials available for dinitrochlorobenzene and Breast Neoplasms

ArticleYear
Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.
    The British journal of dermatology, 1997, Volume: 137, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Dose-Response Rel

1997
Effect of treatment on the immunological status of women with advanced breast cancer.
    British journal of cancer, 1979, Volume: 39, Issue:6

    Topics: Antibody Formation; Antigens; Antineoplastic Agents; Breast Neoplasms; Dinitrochlorobenzene; Female;

1979
Local delayed cutaneous hypersensitivity reactions in breast cancer patients with and without removal of axillary lymph nodes.
    American journal of surgery, 1976, Volume: 132, Issue:1

    Topics: Animals; Breast Neoplasms; Clinical Trials as Topic; Dinitrochlorobenzene; Disease Models, Animal; F

1976

Other Studies

32 other studies available for dinitrochlorobenzene and Breast Neoplasms

ArticleYear
GST isoenzymes in matched normal and neoplastic breast tissue.
    Neoplasma, 2011, Volume: 58, Issue:4

    Topics: Blotting, Western; Breast Neoplasms; Dinitrochlorobenzene; Epoxy Compounds; Female; Glutathione Tran

2011
Role of phagocytic cells in cancer.
    Folia haematologica (Leipzig, Germany : 1928), 1981, Volume: 108, Issue:4

    Topics: Anaerobiosis; Antineoplastic Agents; Breast Neoplasms; Complement Activation; Dinitrochlorobenzene;

1981
Delayed cutaneous hypersensitivity, lymphocyte count, and blood tests in patients with breast carcinoma.
    Journal of surgical oncology, 1984, Volume: 27, Issue:3

    Topics: Blood Chemical Analysis; Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, D

1984
DNCB and PPD skin testing in breast cancer.
    Neoplasma, 1983, Volume: 30, Issue:4

    Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Immunity, Innate; Middle Aged; Neoplasm Stag

1983
[Immunotherapy of cancer using levamisole, immunologic control of the post-surgical patient and graphic follow-up].
    Revista espanola de oncologia, 1980, Volume: 27, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Dinitrochlorobenzene; Fema

1980
Immunocompetence, immunosuppression, and human breast cancer. II. Further evidence of initial immune impairment by integrated assessment effect of nodal involvement (N) and of primary tumor size (T).
    Cancer, 1980, Apr-15, Volume: 45, Issue:8

    Topics: Adult; Aged; Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Immunizatio

1980
[Cellular immunity indices in benign breast tumors].
    Voprosy onkologii, 1980, Volume: 26, Issue:5

    Topics: Adenofibroma; Adult; Aged; Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Hypersensitivity,

1980
Immunologic reactivity and prognosis in breast cancer.
    Cancer, 1980, Oct-15, Volume: 46, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Dinitrochlorobenzene; Female;

1980
[Effect of fenformin and miscleron on the delayed hypersensitivity reaction in breast cancer patients].
    Voprosy onkologii, 1980, Volume: 26, Issue:12

    Topics: Breast Neoplasms; Clofibrate; Dinitrochlorobenzene; Drug Therapy, Combination; Female; Humans; Hyper

1980
Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1.
    Toxicology and applied pharmacology, 1999, Jun-01, Volume: 157, Issue:2

    Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Breast Neoplasms; Carrier Proteins; Cell

1999
Immunologic reactivity in patients with primary operable breast cancer.
    Cancer, 1978, Volume: 41, Issue:1

    Topics: B-Lymphocytes; Breast Diseases; Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Immunity; Im

1978
[DNCB test and immune competence. Analysis of patients with urologic neoplasms].
    MMW, Munchener medizinische Wochenschrift, 1978, Aug-04, Volume: 120, Issue:31

    Topics: Breast Neoplasms; Dinitrochlorobenzene; Humans; Immunity, Cellular; Nitrobenzenes; Prognosis; Urinar

1978
Immunologic testing as a guide to cancer management.
    The Surgical clinics of North America, 1979, Volume: 59, Issue:2

    Topics: Antibody Formation; Antigen-Antibody Complex; Breast Neoplasms; Colonic Neoplasms; Complement System

1979
[The DNCB skin test and its comparison with the radioimmunological determination of CEA in some types of neoplasms].
    Minerva medica, 1979, May-26, Volume: 70, Issue:25

    Topics: Breast Neoplasms; Carcinoembryonic Antigen; Dinitrochlorobenzene; Female; Gastrointestinal Neoplasms

1979
[The epicutaneous DNCB test and CEA determination in neoplasms of the breast, digestive tract, lung and urogenital system].
    Minerva medica, 1979, Dec-01, Volume: 70, Issue:54

    Topics: Breast Neoplasms; Carcinoembryonic Antigen; Dinitrochlorobenzene; Female; Gastrointestinal Neoplasms

1979
Qualitative DNCB skin test in cancer patients.
    Indian journal of cancer, 1977, Volume: 14, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Midd

1977
Immunocompetence testing in patients with one of the four common operable cancers--a review.
    Clinical bulletin, 1978, Volume: 8, Issue:1

    Topics: Breast Neoplasms; Colonic Neoplasms; Dinitrochlorobenzene; Female; Head and Neck Neoplasms; Humans;

1978
Rapidly progressing breast cancer (poussée évolutive) in Tunisia: studies on delayed hypersensitivity.
    International journal of cancer, 1978, Jul-15, Volume: 22, Issue:1

    Topics: Antigens, Neoplasm; Breast Neoplasms; Cell Line; Dinitrochlorobenzene; Female; Humans; Hypersensitiv

1978
[Immunologic reactivity of breast cancer patients].
    Voprosy onkologii, 1978, Volume: 24, Issue:8

    Topics: Antigens, Bacterial; Antigens, Fungal; Breast Neoplasms; Candida; Dinitrochlorobenzene; Female; Huma

1978
Tests of cell mediated immunity in patients with early breast cancer. I. Response to DNCB at time of mastectomy.
    Clinical oncology, 1978, Volume: 4, Issue:3

    Topics: Adult; Age Factors; Aged; Breast Neoplasms; Cell Migration Inhibition; Dinitrochlorobenzene; Female;

1978
A study of host defence reaction of breast carcinoma and its correlation with generalised delayed hypersensitivity.
    Indian journal of cancer, 1978, Volume: 15, Issue:3

    Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Skin Tests

1978
Nonspecific antigen reactions.
    National Cancer Institute monograph, 1976, Volume: 44

    Topics: Administration, Topical; Antibody Formation; Antigens; Antineoplastic Agents; BCG Vaccine; Breast Ne

1976
Immunocompetence, immunosuppression, and human breast cancer. I. An analysis of their relationship by known parameters of cell-mediated immunity in well-defined clinical stages of disease.
    Cancer, 1976, Volume: 38, Issue:3

    Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Immune Adherence

1976
Adrenalectomy and oophorectomy plus limited-term chemotherapy in the treatment of breast cancer.
    Cancer treatment reports, 1976, Volume: 60, Issue:7

    Topics: Adrenalectomy; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Castration; Dinitrochlorobenzen

1976
Cellular immunity in cancer: comparison of delayed hypersensitivity skin tests in three common cancers.
    British medical journal, 1975, Jul-05, Volume: 3, Issue:5974

    Topics: Antibodies, Neoplasm; Breast Neoplasms; Colonic Neoplasms; Dinitrochlorobenzene; Humans; Hypersensit

1975
Delayed hypersensitivity to DNCB and survival following radiation therapy in patients with solid malignant tumors.
    Radiology, 1975, Volume: 115, Issue:2

    Topics: Adenocarcinoma; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous Cell; Dinitrochlorobenzen

1975
A correlation of DNCB-induced delayed cutaneous hypersensitivity reactions and the course of disease in patients with recurrent breast cancer.
    Cancer, 1976, Volume: 37, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Dinitrochlorobenzene; Female; Humans; Hypersen

1976
Delayed cutaneous hypersensitivity reaction in breast cancer patients.
    Journal of the Indian Medical Association, 1988, Volume: 86, Issue:1

    Topics: Antigens; Antigens, Bacterial; Antigens, Fungal; Breast Neoplasms; Candida albicans; Dinitrochlorobe

1988
Long-term (5-11 years) follow-up of general immune competence in breast cancer. I. Pre-treatment levels with reference to micrometastasis.
    Cancer immunology, immunotherapy : CII, 1986, Volume: 21, Issue:1

    Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Follow-Up Studies; Humans; Immunocompetence; Immunog

1986
Long-term follow-up of general immune competence in breast cancer. II. Sequential pre- and post-treatment levels: a 10 year study.
    Cancer immunology, immunotherapy : CII, 1986, Volume: 21, Issue:1

    Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Follow-Up Studies; Humans; Immunocompetence; Immunog

1986
A short term follow up study on non-specific modulation of CMI by levamisole in advanced breast cancer.
    The Indian journal of medical research, 1985, Volume: 81

    Topics: Adult; Aged; Breast Neoplasms; Dinitrochlorobenzene; Female; Follow-Up Studies; Humans; Immunity, Ce

1985
DNCB and PPD skin tests and prognosis in 152 patients with breast cancer. A prospective 2-year follow-up.
    Neoplasma, 1985, Volume: 32, Issue:1

    Topics: Breast Neoplasms; Dinitrochlorobenzene; Female; Follow-Up Studies; Humans; Immunocompetence; Nitrobe

1985