dinitrochlorobenzene has been researched along with Bladder Cancer in 25 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have done a double-blind, randomized, controlled study on 37 patients with transitional cell carcinoma in which levamisole was used as an immune adjuvant in addition to the standard therapy for non-invasive and invasive bladder cancer." | 9.04 | Levamisole in the treatment of non-invasive and invasive bladder cancer: a preliminary report. ( Baron, B; Dekernion, J; Kaufman, JJ; Skinner, DG; Smith, RB, 1978) |
| "Sixty-two patients with transitional cell carcinoma have been admitted to a double-blind randomized control study with levamisole as an immune adjuvant, in addition to standard therapy for noninvasive and invasive bladder cancer." | 9.04 | Preliminary report of the use of levamisole in the treatment of bladder cancer. ( deKernion, J; Kaufman, JJ; Lincoln, B; Skinner, DG; Smith, RB, 1978) |
| "A group of 40 patients with bilharzial bladder cancer underwent quantitative skin testing with dinitrochlorobenzene and purified protein derivative of tuberculin before radical surgery." | 7.66 | The predictive value of 2,-4, dinitrochlorobenzene skin testing in patients with bilharzial bladder cancer. ( Dawson, DV; El-Mahrouky, AS; Paulson, DF; Sanfilippo, F, 1983) |
| "Levamisole has been shown to be easily administered and is well-tolerated, especially when compared to other immune adjuvants such as bacillus Calmette-Guerin or Corynebacterium parvum." | 6.64 | Preliminary report of the use of levamisole in the treatment of bladder cancer. ( deKernion, J; Kaufman, JJ; Lincoln, B; Skinner, DG; Smith, RB, 1978) |
| "Tumor recurrence seems to be rare in those patients who are initially DNCB-positive." | 6.64 | Preliminary report of the use of levamisole in the treatment of bladder cancer. ( deKernion, J; Kaufman, JJ; Lincoln, B; Skinner, DG; Smith, RB, 1978) |
| "A group of 40 patients with bilharzial bladder cancer underwent quantitative skin testing with dinitrochlorobenzene and purified protein derivative of tuberculin before radical surgery." | 5.27 | The predictive value of 2,-4, dinitrochlorobenzene skin testing in patients with bilharzial bladder cancer. ( Dawson, DV; El-Mahrouky, AS; Paulson, DF; Sanfilippo, F, 1983) |
| "We have done a double-blind, randomized, controlled study on 37 patients with transitional cell carcinoma in which levamisole was used as an immune adjuvant in addition to the standard therapy for non-invasive and invasive bladder cancer." | 5.04 | Levamisole in the treatment of non-invasive and invasive bladder cancer: a preliminary report. ( Baron, B; Dekernion, J; Kaufman, JJ; Skinner, DG; Smith, RB, 1978) |
| "Sixty-two patients with transitional cell carcinoma have been admitted to a double-blind randomized control study with levamisole as an immune adjuvant, in addition to standard therapy for noninvasive and invasive bladder cancer." | 5.04 | Preliminary report of the use of levamisole in the treatment of bladder cancer. ( deKernion, J; Kaufman, JJ; Lincoln, B; Skinner, DG; Smith, RB, 1978) |
| "At present, isoniazid (INH) is being used prophylactically to reduce the side effects of intravesical BCG therapy for superficial bladder cancer, although it is not clear whether or not this reduces the antitumor efficacy of BCG." | 3.68 | Impaired immune response by isoniazid treatment during intravesical BCG administration in the guinea pig. ( de Boer, EC; de Jong, WH; Debruyne, FM; Ruitenberg, EJ; Steerenberg, PA; van der Meijden, AP; van Klingeren, B, 1992) |
| "A group of 40 patients with bilharzial bladder cancer underwent quantitative skin testing with dinitrochlorobenzene and purified protein derivative of tuberculin before radical surgery." | 3.66 | The predictive value of 2,-4, dinitrochlorobenzene skin testing in patients with bilharzial bladder cancer. ( Dawson, DV; El-Mahrouky, AS; Paulson, DF; Sanfilippo, F, 1983) |
| "Levamisole has been shown to be easily administered and is well-tolerated, especially when compared to other immune adjuvants such as bacillus Calmette-Guerin or Corynebacterium parvum." | 2.64 | Preliminary report of the use of levamisole in the treatment of bladder cancer. ( deKernion, J; Kaufman, JJ; Lincoln, B; Skinner, DG; Smith, RB, 1978) |
| "Tumor recurrence seems to be rare in those patients who are initially DNCB-positive." | 2.64 | Preliminary report of the use of levamisole in the treatment of bladder cancer. ( deKernion, J; Kaufman, JJ; Lincoln, B; Skinner, DG; Smith, RB, 1978) |
| "A group of 40 patients with bilharzial bladder cancer underwent quantitative skin testing with dinitrochlorobenzene and purified protein derivative of tuberculin before radical surgery." | 1.27 | The predictive value of 2,-4, dinitrochlorobenzene skin testing in patients with bilharzial bladder cancer. ( Dawson, DV; El-Mahrouky, AS; Paulson, DF; Sanfilippo, F, 1983) |
| "After removal of the primary tumor, recurrences are noted only after a relatively long interval, infiltration of the tumor into bladder muscle being hindered by immunocyte activity." | 1.26 | [Influence of T-lymphocytes in bladder cancer on appearance and infiltration of recurrences (author's transl)]. ( Stöber, U, 1978) |
| "DNCB reactivity among patients with bladder tumors shows progressive reduction with increasing stage disease and lends support to the evidence suggesting immune deficiency in patients with bladder neoplasm." | 1.26 | Immune evaluation with skin testing. A study of testicular, prostatic, and bladder neoplasms. ( Bean, MA; Bracken, RB; Pinsky, CM; Schellhammer, PF; Whitmore, WF, 1976) |
| "The concepts that human tumors elicit cell-mediated immune responses to tumor antigens are re-examined and modified; for example, cell-mediated immunity may be detectable only at certain stages of tumor growth." | 1.26 | Immunotherapy and human tumor immunology. ( Brosman, S; Fahey, JL; O'Toole, C; Ossorio, RC; Zighelboim, J, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (92.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simic, T | 1 |
| Mimic-Oka, J | 1 |
| Savic-Radojevic, A | 1 |
| Opacic, M | 1 |
| Pljesa, M | 1 |
| Dragicevic, D | 1 |
| Djokic, M | 1 |
| Radosavljevic, R | 1 |
| Flamm, J | 3 |
| Sagaster, P | 1 |
| Micksche, M | 1 |
| El-Mahrouky, AS | 1 |
| Dawson, DV | 1 |
| Paulson, DF | 1 |
| Sanfilippo, F | 1 |
| Jakse, G | 1 |
| Hofstädter, F | 1 |
| Märk, R | 1 |
| Burkert, S | 2 |
| Johnson, DK | 1 |
| Pontes, JE | 1 |
| Izbicki, R | 1 |
| Pierce, JM | 1 |
| Bean, MA | 3 |
| Schellhammer, PS | 1 |
| Herr, HW | 1 |
| Pinsky, CM | 2 |
| Whitmore, WF | 2 |
| Klippel, KF | 1 |
| Walz, HP | 1 |
| Kreutz, G | 1 |
| von Moltke, T | 1 |
| Stöber, U | 1 |
| Smith, RB | 2 |
| Dekernion, J | 2 |
| Baron, B | 1 |
| Skinner, DG | 2 |
| Kaufman, JJ | 2 |
| Lincoln, B | 1 |
| Brosman, S | 3 |
| Elhilali, M | 1 |
| Vescera, C | 2 |
| Fahey, J | 1 |
| Elhilali, MM | 1 |
| Brosman, SA | 1 |
| Paul, JG | 1 |
| Fahey, JL | 3 |
| Imai, Y | 1 |
| Adolphs, HD | 2 |
| Steffens, L | 2 |
| Lamm, DL | 1 |
| Harris, SC | 1 |
| Gittes, RF | 1 |
| Duclos, H | 1 |
| Schwarzenberg, L | 1 |
| Duclos, SH | 1 |
| Hugues, H | 1 |
| Kuss, R | 1 |
| Dorey, F | 1 |
| Schellhammer, PF | 1 |
| Bracken, RB | 1 |
| Catalona, WJ | 1 |
| Smolev, JK | 1 |
| Harty, JI | 1 |
| Ossorio, RC | 1 |
| O'Toole, C | 1 |
| Zighelboim, J | 1 |
| de Boer, EC | 1 |
| Steerenberg, PA | 1 |
| van der Meijden, AP | 1 |
| van Klingeren, B | 1 |
| de Jong, WH | 1 |
| Debruyne, FM | 1 |
| Ruitenberg, EJ | 1 |
1 review available for dinitrochlorobenzene and Bladder Cancer
| Article | Year |
|---|---|
Some immunological considerations relevant to the study of human bladder cancer.
Topics: Aged; Animals; Antigens, Neoplasm; Cross Reactions; Cytotoxicity Tests, Immunologic; Dinitrochlorobe | 1977 |
2 trials available for dinitrochlorobenzene and Bladder Cancer
| Article | Year |
|---|---|
Levamisole in the treatment of non-invasive and invasive bladder cancer: a preliminary report.
Topics: Aged; Antigens, Neoplasm; Carcinoma, Transitional Cell; Chemotaxis, Leukocyte; Clinical Trials as To | 1978 |
Preliminary report of the use of levamisole in the treatment of bladder cancer.
Topics: Carcinoma, Transitional Cell; Chemotaxis, Leukocyte; Clinical Trials as Topic; Dinitrochlorobenzene; | 1978 |
22 other studies available for dinitrochlorobenzene and Bladder Cancer
| Article | Year |
|---|---|
Glutathione S-transferase T1-1 activity upregulated in transitional cell carcinoma of urinary bladder.
Topics: Carcinoma, Transitional Cell; Dinitrochlorobenzene; Glutathione Transferase; Humans; Substrate Speci | 2005 |
The value of the DNCB test in bladder cancer. Pretreatment evaluation of immune function and 5-year follow-up of patients with urinary bladder cancer.
Topics: Aged; Dinitrochlorobenzene; Female; Humans; Immunoglobulins; Male; Neoplasm Invasiveness; Neoplasm R | 1984 |
The predictive value of 2,-4, dinitrochlorobenzene skin testing in patients with bilharzial bladder cancer.
Topics: Dinitrochlorobenzene; Humans; Immunity, Cellular; Nitrobenzenes; Schistosomiasis; Skin Tests; Tuberc | 1983 |
Specific red cell adherence test and unspecific immune response in patients with superficial bladder cancer.
Topics: Aged; Carcinoma in Situ; Carcinoma, Transitional Cell; Chemotaxis, Leukocyte; Dinitrochlorobenzene; | 1981 |
[Correlation of the immune profile with local immunocyte infiltration in urinary bladder tumours (author's transl)].
Topics: Aged; Carcinoma; Dinitrochlorobenzene; Female; Humans; Lymphocytes; Male; Middle Aged; Skin Tests; U | 1982 |
[The prognostic significance of the immune status (DNCB-test) in patients with carcinoma of the bladder, checked by observation of the course of disease (author's transl)].
Topics: Aged; Dinitrochlorobenzene; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Nitr | 1981 |
Prophylaxis of FANFT induced bladder tumours in rats by intravesical DNCB instillation.
Topics: Administration, Topical; Animals; Carcinoma, Transitional Cell; Dinitrochlorobenzene; FANFT; Female; | 1980 |
Immunocompetence of patients with transitional cell carcinoma as measured by dinitrochlorobenzene skin tests and in vitro lymphocyte function.
Topics: Carcinoma, Transitional Cell; Concanavalin A; Dinitrochlorobenzene; Humans; In Vitro Techniques; Lym | 1978 |
[DNCB test and immune competence. Analysis of patients with urologic neoplasms].
Topics: Breast Neoplasms; Dinitrochlorobenzene; Humans; Immunity, Cellular; Nitrobenzenes; Prognosis; Urinar | 1978 |
[Influence of T-lymphocytes in bladder cancer on appearance and infiltration of recurrences (author's transl)].
Topics: Dinitrochlorobenzene; Female; Humans; Recurrence; Skin Tests; T-Lymphocytes; Urinary Bladder Neoplas | 1978 |
Immune response in bladder cancer patients.
Topics: Adult; Aged; Antibody-Dependent Cell Cytotoxicity; Croton Oil; Cytotoxicity Tests, Immunologic; Dini | 1979 |
The effects of treatment on delayed cutaneous hypersensitivity responses (DNCB, croton oil, and recall antigen) in patients with genitourinary cancer.
Topics: Antigens; Croton Oil; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Kidney Neopla | 1978 |
[ The clinical and pathological study of bladder cancer. I. Immune evaluation with skin testing (author's transl)].
Topics: Adult; Aged; Dinitrochlorobenzene; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Ma | 1978 |
Correlation between tumour stage, tumour grade, and immunocompetence in patients with carcinoma of the bladder and prostate.
Topics: Adenocarcinoma; Antibody Formation; Carcinoma, Transitional Cell; Dinitrochlorobenzene; Female; Huma | 1977 |
Bacillus Calmette-Guérin and dinitrochlorobenzene immunotherapy of chemically induced bladder tumors.
Topics: Animals; BCG Vaccine; Dinitrochlorobenzene; FANFT; Female; Immunization; Methods; Neoplasms, Experim | 1977 |
Evaluation of the immunocompetance of patients with transitional cell carcinoma of the bladder.
Topics: Adult; Aged; Antibody Formation; Carcinoma, Transitional Cell; Dinitrochlorobenzene; Drug Hypersensi | 1977 |
Cutaneous response to dinitrochlorobenzene in patients with genito-urinary cancers.
Topics: Dinitrochlorobenzene; Female; Humans; Immunity, Cellular; Kidney Neoplasms; Male; Nitrobenzenes; Pen | 1977 |
Immunological responsiveness in patients with bladder cancer.
Topics: Antigens; Carcinoma, Transitional Cell; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Imm | 1977 |
Immune evaluation with skin testing. A study of testicular, prostatic, and bladder neoplasms.
Topics: Adolescent; Adult; Aged; Antibody Formation; Carcinoma; Carcinoma, Papillary; Dinitrochlorobenzene; | 1976 |
Prognostic value of host immunocompetence in urologic cancer patients.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Transitional Cell; Dinitrochlorobenzene; Female; Follow-Up S | 1975 |
Immunotherapy and human tumor immunology.
Topics: BCG Vaccine; Dinitrochlorobenzene; Immunity, Cellular; Immunotherapy; Leukemia; Neoplasms; Propionib | 1976 |
Impaired immune response by isoniazid treatment during intravesical BCG administration in the guinea pig.
Topics: Administration, Intravesical; Animals; BCG Vaccine; Dinitrochlorobenzene; Female; Guinea Pigs; Histo | 1992 |