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dinitrochlorobenzene and Bilirubinemia

dinitrochlorobenzene has been researched along with Bilirubinemia in 2 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Research Excerpts

ExcerptRelevanceReference
"The effect of hyperbilirubinemia on the function of tissue efflux transporters such as multidrug resistance-associated proteins (Mrps) and organic anion transporting polypeptides (Oatps) was examined by measuring tissue accumulation of 2,4-dinitrophenyl-S-glutathione (DNP-SG) after intravenous administration of 1-chloro-2,4-dinitrobenzene (CDNB), a precursor of DNP-SG, in rats."7.76Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"Treatment with probenecid, an inhibitor for both Mrps and Oatps, significantly increased DNP-SG concentrations in the brain, heart, liver, kidney, jejunum, spleen and skeletal muscle as compared with those in control rats, suggesting the expression of some probenecid-sensitive efflux transporters in these tissues."5.36Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"Hyperbilirubinemia was induced by a bolus intravenous administration of bilirubin."5.36Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"The effect of hyperbilirubinemia on the function of tissue efflux transporters such as multidrug resistance-associated proteins (Mrps) and organic anion transporting polypeptides (Oatps) was examined by measuring tissue accumulation of 2,4-dinitrophenyl-S-glutathione (DNP-SG) after intravenous administration of 1-chloro-2,4-dinitrobenzene (CDNB), a precursor of DNP-SG, in rats."5.36Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"The effect of hyperbilirubinemia on the function of tissue efflux transporters such as multidrug resistance-associated proteins (Mrps) and organic anion transporting polypeptides (Oatps) was examined by measuring tissue accumulation of 2,4-dinitrophenyl-S-glutathione (DNP-SG) after intravenous administration of 1-chloro-2,4-dinitrobenzene (CDNB), a precursor of DNP-SG, in rats."3.76Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"The function of multidrug resistance-associated protein 2 (Mrp2) in the intestine and liver, as well as intestinal Mrp2 expression, was analyzed in CCl(4)-induced acute hepatic failure rats with hyperbilirubinemia."3.73Function of multidrug resistance-associated protein 2 in acute hepatic failure rats. ( Murakami, T; Nagai, J; Takano, M; Yokooji, T; Yumoto, R, 2006)
"Treatment with probenecid, an inhibitor for both Mrps and Oatps, significantly increased DNP-SG concentrations in the brain, heart, liver, kidney, jejunum, spleen and skeletal muscle as compared with those in control rats, suggesting the expression of some probenecid-sensitive efflux transporters in these tissues."1.36Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"Hyperbilirubinemia was induced by a bolus intravenous administration of bilirubin."1.36Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"The effect of hyperbilirubinemia on the function of tissue efflux transporters such as multidrug resistance-associated proteins (Mrps) and organic anion transporting polypeptides (Oatps) was examined by measuring tissue accumulation of 2,4-dinitrophenyl-S-glutathione (DNP-SG) after intravenous administration of 1-chloro-2,4-dinitrobenzene (CDNB), a precursor of DNP-SG, in rats."1.36Modulated function of tissue efflux transporters under hyperbilirubinemia in rats. ( Mori, N; Murakami, T; Yokooji, T, 2010)
"These results suggest that hyperbilirubinemia in disease states may be related to the systemic suppression of Mrp2 function."1.33Function of multidrug resistance-associated protein 2 in acute hepatic failure rats. ( Murakami, T; Nagai, J; Takano, M; Yokooji, T; Yumoto, R, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yokooji, T2
Mori, N1
Murakami, T2
Yumoto, R1
Nagai, J1
Takano, M1

Other Studies

2 other studies available for dinitrochlorobenzene and Bilirubinemia

ArticleYear
Modulated function of tissue efflux transporters under hyperbilirubinemia in rats.
    European journal of pharmacology, 2010, Jun-25, Volume: 636, Issue:1-3

    Topics: Animals; Bilirubin; Dinitrochlorobenzene; Gene Expression Regulation; Glutathione; Hyperbilirubinemi

2010
Function of multidrug resistance-associated protein 2 in acute hepatic failure rats.
    European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3

    Topics: Adenosine Triphosphate; Animals; Area Under Curve; ATP-Binding Cassette Transporters; Bile; Bilirubi

2006