Page last updated: 2024-10-15

dinitrochlorobenzene and B16 Melanoma

dinitrochlorobenzene has been researched along with B16 Melanoma in 2 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Research Excerpts

ExcerptRelevanceReference
"An empirically established chemoimmunotherapy for metastatic melanoma combines the systemic administration of the chemotherapeutic agent dacarbazine (DTIC) with the epifocal application of the contact sensitizer 2,4-dinitrochlorobenzene (DNCB) on cutaneous metastases."7.71Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002)
"Subcutaneous (s."5.31Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002)
"An empirically established chemoimmunotherapy for metastatic melanoma combines the systemic administration of the chemotherapeutic agent dacarbazine (DTIC) with the epifocal application of the contact sensitizer 2,4-dinitrochlorobenzene (DNCB) on cutaneous metastases."3.71Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002)
"An empirically established chemoimmunotherapy that combines the epifocal application of the contact sensitizer dinitrochlorobenzene (DNCB) to cutaneous metastases with the systemic administration of dacarbazine (DTIC) yields high response rates and results in prolonged survival."3.71Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model. ( Becker, JC; Bröcker, EB; Fischer, WH; Lutz, WK; Wack, C, 2001)
"Subcutaneous (s."1.31Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. ( Becker, JC; Bröcker, EB; Fischer, WH; Kirst, A; Lutz, WK; Wack, C, 2002)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wack, C2
Kirst, A1
Becker, JC2
Lutz, WK2
Bröcker, EB2
Fischer, WH2

Other Studies

2 other studies available for dinitrochlorobenzene and B16 Melanoma

ArticleYear
Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response.
    Cancer immunology, immunotherapy : CII, 2002, Volume: 51, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarb

2002
Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model.
    Melanoma research, 2001, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Dinitrochloroben

2001