Page last updated: 2024-10-15

dinitrochlorobenzene and Autoimmune Disease

dinitrochlorobenzene has been researched along with Autoimmune Disease in 9 studies

Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.

Research Excerpts

ExcerptRelevanceReference
" Obligate contact sensitizers such as diphencyprone or dinitrochlorobenzene have been used against viral and autoimmune diseases."3.72[Topical immunomodulators in dermatology]. ( Hengge, UR; Meykadeh, N, 2003)
"Sixty-four patients suffering from senile dementia were compared with 71 age-matched controls suffering from functional psychiatric illness, in terms of their chromosome complement, tuberculin and dinitrochlorobenzene response and total immunoglobulin levels."3.66Immunological factors in senile dementia. ( Fry, AH; Kellett, JM; Martin, JM, 1982)
"Long-term treatment of alopecia areata with dinitrochlorobenzene is effective."3.66[DNCB therapy of alopecia areata]. ( Happle, R, 1979)
"Eleven thymectomized and ten non-thymectomized patients with myasthenia gravis, matched with respect to sex, age, duration and severity of the disease were investigated with respect to routine clinical features, electrophysiological examination, HLA-typing, auto-antibodies, lymphocyte subpopulations in peripheral blood, Concanavalin A-induced release of leucocyte migration inhibitory factor (LIF), in vitro lymphocyte activation by mitogens and antigens and response to primary immunization with dinitrochlorobenzene measured in vivo and in vitro."3.66Immunological studies in thymectomized and non-thymectomized patients with myasthenia gravis. ( Andersen, V; Bendtzen, K; Fulpius, BW; Krarup, C; Monnier, VM; Permin, H; Platz, P; Søeberg, B; Sørensen, SF; Thomsen, M, 1978)
"Alopecia areata is considered an autoimmune disease."1.26Antigenic competition as a therapeutic concept for alopecia areata. ( Happle, R, 1980)
"Sixty-four patients suffering from senile dementia were compared with 71 age-matched controls suffering from functional psychiatric illness, in terms of their chromosome complement, tuberculin and dinitrochlorobenzene response and total immunoglobulin levels."1.26Immunological factors in senile dementia. ( Fry, AH; Kellett, JM; Martin, JM, 1982)
"Long-term treatment of alopecia areata with dinitrochlorobenzene is effective."1.26[DNCB therapy of alopecia areata]. ( Happle, R, 1979)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meykadeh, N1
Hengge, UR1
Happle, R2
Kellett, JM1
Martin, JM1
Fry, AH1
Sørensen, SF1
Andersen, V1
Bendtzen, K1
Fulpius, BW1
Krarup, C1
Monnier, VM1
Permin, H1
Platz, P1
Søeberg, B1
Thomsen, M1
Niwa, Y1
Kanoh, T1
Sarti, G1
Savorani, G1
Thompson, CD1
Whittingham, S2
Mackay, IR2
Khoo, SK1
Toh, BH1
Stagg, RJ1
Youngchaiyud, U1
Buckley, JD1
Morris, PJ1

Other Studies

9 other studies available for dinitrochlorobenzene and Autoimmune Disease

ArticleYear
[Topical immunomodulators in dermatology].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2003, Volume: 54, Issue:7

    Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Aged; Aged, 80 and over; Aminoquinolines; As

2003
Antigenic competition as a therapeutic concept for alopecia areata.
    Archives of dermatological research, 1980, Volume: 267, Issue:1

    Topics: Alopecia Areata; Antibody Formation; Antigen-Antibody Reactions; Autoimmune Diseases; Binding, Compe

1980
Immunological factors in senile dementia.
    Acta psychiatrica Scandinavica, 1982, Volume: 66, Issue:5

    Topics: Aged; Alzheimer Disease; Aneuploidy; Autoimmune Diseases; Dementia; Dinitrochlorobenzene; Female; Hu

1982
[DNCB therapy of alopecia areata].
    Zeitschrift fur Hautkrankheiten, 1979, May-15, Volume: 54, Issue:10

    Topics: Alopecia Areata; Autoimmune Diseases; Binding, Competitive; Cyclobutanes; Dinitrochlorobenzene; Huma

1979
Immunological studies in thymectomized and non-thymectomized patients with myasthenia gravis.
    Journal of clinical & laboratory immunology, 1978, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Aged; Autoantibodies; Autoimmune Diseases; Connective Tissue Diseases; Dinitrochl

1978
Immune deficiency states and immune imbalance in systemic lupus erythematosus and other autoimmune diseases.
    Clinical immunology and immunopathology, 1979, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Antibodies, Viral; Antibody Formation; Antitoxins; Autoimmune Diseases; Dinitroch

1979
[Evaluation of cellular immunity in man using skin tests (methods)].
    Bollettino della Societa italiana di biologia sperimentale, 1976, Jun-30, Volume: 52, Issue:12

    Topics: Allergens; Antibody Formation; Autoimmune Diseases; Dinitrochlorobenzene; Humans; Hypersensitivity,

1976
Quantitation of cell-mediated immunity: responses to dinitrochlorobenzene and ubiquitous antigens.
    Canadian Medical Association journal, 1975, May-03, Volume: 112, Issue:9

    Topics: Adolescent; Adult; Aged; Antigen-Antibody Reactions; Antigens; Autoimmune Diseases; Carrier Proteins

1975
Thyrogastric autoimmune disease. Studies on the cell-mediated immune system and histocompatibility antigens.
    Clinical and experimental immunology, 1975, Volume: 19, Issue:2

    Topics: Anemia, Pernicious; Autoantibodies; Autoimmune Diseases; Cell Migration Inhibition; Dinitrochloroben

1975