dinitrochlorobenzene has been researched along with Acquired Immune Deficiency Syndrome in 13 studies
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.
1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dinitrochlorobenzene (DNCB) is an inexpensive contact sensitizing agent that stimulates cell-mediated immunity when applied to the skin." | 2.68 | Topical immune modulation with dinitrochlorobenzene in HIV disease: a controlled trial from Brazil. ( Margulis, SB; Stricker, RB; Traub, A, 1997) |
| "In contrast, AIDS developed in 5 of the 11 noncompliant patients and four of these patients died." | 1.29 | Clinical and immunologic evaluation of HIV-infected patients treated with dinitrochlorobenzene. ( Dumlao, C; Elswood, BF; Epstein, WL; Goldberg, B; Henry, J; Stricker, RB; Van Elk, J; Winger, EE, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McLeod, WA | 2 |
| Jeffries, E | 1 |
| Boyko, W | 1 |
| Arnott, NM | 1 |
| Stricker, RB | 6 |
| Goldberg, B | 3 |
| Elswood, BF | 3 |
| Dumlao, C | 1 |
| Van Elk, J | 1 |
| Henry, J | 1 |
| Winger, EE | 1 |
| Epstein, WL | 2 |
| Stone, OJ | 1 |
| Traub, A | 1 |
| Margulis, SB | 1 |
| Marion, SA | 1 |
| Schechter, MT | 1 |
| Weaver, MS | 1 |
| Boyko, WJ | 1 |
| Willoughby, B | 1 |
| Douglas, B | 1 |
| Craib, KJ | 1 |
| O'Shaughnessy, M | 1 |
| Madhok, R | 1 |
| Gracie, A | 1 |
| Lowe, GD | 1 |
| Burnett, A | 1 |
| Froebel, K | 1 |
| Follett, E | 1 |
| Forbes, CD | 1 |
| Rietmeijer, CA | 1 |
| Cohn, DL | 1 |
| Mills, LB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Epidermal Langerhans Cell Population in AIDS / ARC Patients by the Topical Application of a Potent Contact Allergen (1-Chloro-2,4-Dinitro-Chlorobenzene) (DNCB)[NCT00002031] | 0 participants | Interventional | Completed | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dinitrochlorobenzene and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Topical immune modulation (TIM): a novel approach to the immunotherapy of systemic disease.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Administration, Topical; Anti-HIV Agents | 1997 |
Dendritic cells and dinitrochlorobenzene (DNCB): a new treatment approach to AIDS.
Topics: Acquired Immunodeficiency Syndrome; Dendritic Cells; Dinitrochlorobenzene; HIV; Humans; Langerhans C | 1991 |
1 trial available for dinitrochlorobenzene and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Topical immune modulation with dinitrochlorobenzene in HIV disease: a controlled trial from Brazil.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Administration, Cutaneous; Adult; Anti-H | 1997 |
10 other studies available for dinitrochlorobenzene and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Screening for acquired immune deficiency syndrome with dinitrochlorobenzene.
Topics: Acquired Immunodeficiency Syndrome; Dinitrochlorobenzene; Humans; Male; Nitrobenzenes; Prospective S | 1984 |
Screening for acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Dinitrochlorobenzene; Humans; Nitrobenzenes | 1983 |
Host-directed therapy for AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Dinitrochlorobenzene; Humans | 1995 |
Clinical and immunologic evaluation of HIV-infected patients treated with dinitrochlorobenzene.
Topics: Acquired Immunodeficiency Syndrome; Antigens, CD; CD4-CD8 Ratio; Dinitrochlorobenzene; Flow Cytometr | 1994 |
Delayed-type hypersensitivity and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed | 1994 |
Inducing viral immunity without a vaccine--possible use with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Dermatitis, Contact; Dermatitis, Toxicodendron; Dinitrochloroben | 1993 |
Evidence that prior immune dysfunction predisposes to human immunodeficiency virus infection in homosexual men.
Topics: Acquired Immunodeficiency Syndrome; Candida; Dinitrochlorobenzene; Disease Susceptibility; Homosexua | 1989 |
Impaired cell mediated immunity in haemophilia in the absence of infection with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Blood Coagulation Factors; Dinitrochlorobenzene; Hemophilia A; H | 1986 |
Severe allergic contact dermatitis from dinitrochlorobenzene in a patient with human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Dermatitis, Contact; Dinitrochlorobenzene; Humans; Male | 1988 |
Stimulation of T-cellular immunity by cutaneous application of dinitrochlorobenzene.
Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Dinitrochlorobenzene; Humans; Nitrobenz | 1986 |