dinitrobenzenes and Mucocutaneous-Lymph-Node-Syndrome

dinitrobenzenes has been researched along with Mucocutaneous-Lymph-Node-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for dinitrobenzenes and Mucocutaneous-Lymph-Node-Syndrome

ArticleYear
Possible polyclonal B cell activation in mucocutaneous lymph node syndrome.
    European journal of pediatrics, 1986, Volume: 145, Issue:1-2

    Immunoserological studies on polyclonal B cell activation were carried out on 39 patients with mucocutaneous lymph node syndrome (MCLS) and in age-matched healthy individuals. The incidence of anti-mite, P. acnes (Kato) and EB virus antibodies, recently proposed as aetiological agents by some investigators, was increased in the patient group. Serum immunoglobulin (Ig) M level and IgM-anti-dinitrophenyl (DNP) antibodies, which are considered to be parameters of polyclonal B cell activation, were determined in MCLS cases. The level of serum IgM in MCLS was significantly elevated (0.02 less than P less than 0.05). Levels of anti-DNP antibodies in seven cases of MCLS (18%) were significantly higher than those of the controls (P less than 0.01). Nine of the ten pair sera in MCLS showed a stage-dependent decrease in anti-DNP antibodies. These results suggest that polyclonal B cell activation occurs in MCLS.

    Topics: Antibodies; Antibodies, Bacterial; Antibodies, Viral; B-Lymphocytes; Child; Child, Preschool; Dinitrobenzenes; Fluorescent Antibody Technique; Herpesvirus 4, Human; Humans; Immunoglobulin G; Immunoglobulin M; Infant; Lymphocyte Activation; Mites; Mucocutaneous Lymph Node Syndrome; Propionibacterium acnes

1986