dinitrobenzenes has been researched along with Mast-Cell-Sarcoma* in 3 studies
3 other study(ies) available for dinitrobenzenes and Mast-Cell-Sarcoma
| Article | Year |
|---|---|
Adjuvant activity of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds.
Adjuvant and antitumor activities of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine were examined. All the synthetic 6-O-corynomycoloyl-, 6-O-mocardomycoloyl-, and 6-O-mycoloyl-N-acetylmuramyl-L-alanyl-D-isoglutamine were active as adjuvants for cell-mediated immune responses. However, 6-O-mycoloyl-N-acetylmuramyl-L-alanyl-D-isoglutamine was less active as an adjuvant on circulating antibody formation. It was shown that pyrogenic activity of N-acetylmuramyldipeptide was reduced by 6-O-acylation with mycolic acid, but not with nocardomycolic or corynomycolic acid. Tumor-suppression activity was observed by the synthetic 6-O-mycoloyl-N-acetylmuramyl-L-alanyl-D-isoglutamine by using transplantable tumor in syngenic mice. Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Antibodies; Antibody-Dependent Cell Cytotoxicity; Dinitrobenzenes; Female; Glycopeptides; Guinea Pigs; Immunity, Cellular; Lymphocyte Cooperation; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred Strains; Mitogens; Mycolic Acids; Sarcoma, Experimental; T-Lymphocytes | 1978 |
Studies on lymphocyte-mediated cytolysis. XII. Hapten transferred to cell surfaces by interaction with liposomes is recognized by antibody but not by hapten-specific H-2 restricted cytotoxic T cells.
Topics: Animals; Antibodies; Cell Membrane; Cytotoxicity, Immunologic; Dinitrobenzenes; Haptens; Histocompatibility Antigens; Liposomes; Lymphocytes; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL; Rabbits; T-Lymphocytes | 1978 |
Potentiation of cytotoxic T-cell function by virus.
Inoculation of C57BL/6J mice with allogeneic P815 mastocytoma cells in the presence of simian virus 40 (SV40), a DNA tumor virus, led to an enhanced cytolytic T-cell response to P815 in vivo. Cytotoxic function was also augmented if SV40 was given subsequent to a primary immunization, even when mice were given a suboptimal dose of immunizing cells. Although SV40 increased the cell-mediated immune response to allogeneic cells, it did not enhance the antibody response to the soluble antigen dinitrophenyl bovine gamma-globulin, a helper T-cell-dependent response. Thus it appeared that SV40 had a selective adjuvant effect on lymphocyte subpopulations, since it increased cytotoxicity but not helper T-cell function. Topics: Animals; Antibody Formation; B-Lymphocytes; Cytotoxicity Tests, Immunologic; Dinitrobenzenes; Female; gamma-Globulins; Immunity, Cellular; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Simian virus 40; T-Lymphocytes; Transplantation, Homologous | 1976 |