dinitrobenzenes and Depressive-Disorder--Major

Poor mood, lack of pleasure, reduced focus, remorse, unpleasant thoughts, and sleep difficulties are all symptoms of depression. The only approved treatment for children and adolescents with major depressive disorder (MDD) is fluoxetine hydrochloride (FXN), a serotonin selective reuptake inhibitor antidepressant. MDD is the most common cause of disability worldwide. In the present research, picric acid (PA); dinitrobenzene; p-nitro benzoic acid; 2,6-dichloroquinone-4-chloroimide; 2,6-dibromoquinone-4-chloroimide; and 7,7',8,8'-tetracyanoquinodimethane were used to make 1:1 FXN charge-transfer compounds in solid and liquid forms. The isolated complexes were then characterized by elemental analysis, conductivity, infrared, Raman, and

Topics: Adolescent; Antidepressive Agents; Benzoic Acid; Child; Depressive Disorder, Major; Dinitrobenzenes; Dopamine; Fluoxetine; Humans; Molecular Docking Simulation; Picrates; Selective Serotonin Reuptake Inhibitors; Serotonin