diminazene and Trypanosomiasis, African

diminazene has been researched along with Trypanosomiasis, African in 214 studies

Research

Studies (214)

TimeframeStudies, this research(%)All Research%
pre-199073 (34.11)18.7374
1990's68 (31.78)18.2507
2000's24 (11.21)29.6817
2010's41 (19.16)24.3611
2020's8 (3.74)2.80

Authors

AuthorsStudies
Delfín, DA; Fotie, J; Kaiser, M; Li, C; Maes, L; Mahasenan, KV; Manley, J; Paris, JM; Reid, CS; Wenzler, T; Werbovetz, KA1
Balogun, EO; Bruggeman, V; Dardonville, C; de Koning, HP; Donachie, A; Ebiloma, GU; Fueyo González, FJ; Harada, S; Inaoka, DK; Izquierdo García, C; Kita, K; Sánchez Villamañán, JM; Shiba, T1
Balabadi, D; Essodina, T; Martin Bienvenu, S; Soudah, B; Toï, N; Wendemanegde Ernest, S; Yao, L1
Erin, JP; Kolawole, BJ; Nwoha, RIO; Orakpoghenor, O1
Ekloh, W; Gwira, TM; Sunter, JD1
Eastwood, G; Hakizimana, JN; Mafie, E; Mboera, LEG; Nzalawahe, J; Ogola, K; Okello, I1
Alusi, PM; Auma, JE; Chemuliti, JK; Kurgat, RK; Mdachi, RE; Mugunieri, LG; Mukiria, PW; Ogolla, KO; Okoth, SO; Wamwiri, FN; Wanjala, KB1
Farikou, O; Kamga, RMN; Magang, MEK; Mewamba, EM; Ravel, S; Simo, G; Tiofack, AAZ; Tume, C1
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK1
Barrett, MP; Campagnaro, GD; Carruthers, LV; De Koning, HP; Donachie, AM; Ebiloma, GU; Jayaraman, S; Lemgruber, L; Morrison, LJ; Munday, JC; Peter, R; Rowan, TG; Steketee, P; Ungogo, MA1
Inoue, N; Molefe, NI; Suganuma, K1
Cecchi, G; Clausen, PH; Delespaux, V; Fafetine, J; Hoppenheit, A; Mulandane, FC; Neves, L; Oosthuizen, M; Van Den Abbeele, J1
Araújo, MSS; Bassi, PB; Bittar, ER; Bittar, JFF; Costa E Silva, MF; de Araújo, FF; de Souza Gomes, M; Garcia, GC; Martins-Filho, OA; Nascentes, GAN; Oliveira, CJF; Rodrigues do Amaral, L; Rodrigues Junior, V; Vinícius da Silva, M1
Adeleye, AI; Adeleye, OE; Adeyemi, SO; Ale, JM; Durotoye, LA; Olukunle, JO; Sogebi, EOA1
Adam, Y; Bayala, B; Belem, AMG; Bengaly, Z; Cecchi, G; Delespaux, V; Sidibé, I; Somda, MB; Têko-Agbo, A; Van Den Abbeele, J; Vitouley, SH; Zongo, A1
Batawui, K; Bauer, B; Clausen, PH; Delespaux, V; Den Abbeele, JV; Hoppenheit, A; Kulo, AE; Tchamdja, E1
Jia, P; Kuriakose, SM; Onyilagha, C; Singh, R; Uzonna, JE1
Waiswa, C; Wangoola, MR1
Ademola, IO; Macleod, ET; Odeniran, PO; Welburn, SC1
Adjimani, JP; Amisigo, CM; Antwi, CA; Gwira, TM1
Ezeh, IO; Ezeokonkwo, RC; Idika, IK; Iheagwam, CN; Obi, CF; Obidike, RI; Omoja, VU1
Aluwong, T; Ambali, SF; Ayo, JO; Kobo, PI; Maikai, V; Zezi, AU1
Isaac, AO; Nyariki, JN; Rashid, K; Wachira, FN1
Asres, K; Bisrat, D; Terefe, G; Tewabe, Y1
Feyera, T; Shibeshi, W; Terefe, G1
Allamanda, P; Angeles, JM; Hakimi, H; Inoue, N; Kawazu, S; Suganuma, K; Zhou, M1
Chekwube, AI; Ezeokonkwo, RC; Ikenna, UE; Onyema, EI1
Hatendorf, J; Kabasa, JD; Muhanguzi, D; Picozzi, K; Thrusfield, M; Waiswa, C; Welburn, SC2
De Deken, R; Delespaux, V; Duchateau, L; Moti, Y; Thys, E; Van Den Abbeele, J1
Abebe, G; Barry, D; Dagnachew, S; Goddeeris, B; McCulloch, R; Terefe, G1
Bockstal, V; Cnops, J; De Trez, C; Magez, S; Miquel, MC; Radwanska, M1
Ademola, IO; Odeniran, PO1
Gachie, BM; Kagira, JM; Karanja, SM; Maina, NW; Maranga, DN; Ngotho, M; Waema, MW1
Adjahoutonon, B; Cossic, BGA; Dibanganga, GL; Gloaguen, P; Leroy, P; MacLeod, ET; Maganga, G; Picozzi, K1
Adomefa, K; Bankolé, AA; Batawui, K; Cecchi, G; Clausen, PH; De Deken, R; Delespaux, V; Hoppenheit, A; Kulo, AE; Marcotty, T; Tchamdja, E; Van Den Abbeele, J; Vitouley, HS1
Delespaux, V; Dinka, H; Geerts, S; Masumu, J; Van den Bossche, P1
Aliyu, MM; Ibrahim, UI; Mbaya, AW; Nwosu, CO; Taiwo, VO1
Farah, IO; Hau, J; Jensen, HE; Kagira, JM; Karanja, SM; Ngotho, M1
Avery, VM; Sykes, ML1
Betbeder, D; Daulouede, S; Howsam, M; Jallouli, Y; Karembe, H; Kroubi, M; Mossalayi, D; Vincendeau, P1
Farah, IO; Hau, J; Kagira, JM; Kariuki, C; Maina, N; Mwangangi, DM; Ngotho, M; Thuita, JK1
Kumshe, HA; Mbaya, AW; Nwosu, CO1
Batista, JS; Bezerra, FS; Câmara, AC; García, HA; Olinda, RG; Rebouças, RE; Rodrigues, CM; Silva, TM; Teixeira, MM; Vale, RG1
Anaga, AO; Anika, SM; Asuzu, IU; Ihedioha, TE; Mhomga, LI; Obidike, IR; Omoja, VU; Umeakuana, PU1
Allegye-Cudjoe, E; Bauer, B; Bengaly, Z; Bocoum, Z; Clausen, PH; Delespaux, V; Diall, O; Diarra, B; Geysen, D; Mungube, EO; Randolph, TF; Sidibe, I; Van den Bossche, P; Vitouley, HS1
Chitanga, S; Delespaux, V; Marcotty, T; Namangala, B; Van Den Abbeele, J; Van den Bossche, P1
Akoda, GK; Bengaly, Z; De Deken, R; Delespaux, V; Diallo, A; Marcotty, T; Nebié, RL; Ouédraogo, M; Séré, M; Sidibé, I; Sow, A; Van Den Abbeele, J; Van den Bossche, P; Vitouley, HS1
Anene, BM; Asuzu, IU; Nweze, NE1
Allegye-Cudjoe, E; Bauer, B; Boucoum, Z; Clausen, PH; Diall, O; Diarra, B; Mungube, EO; Randolph, T; Sanogo, Y; Vitouley, HS; Zessin, KH1
Bengaly, Z; Delespaux, V; Marcotty, T; Sidibe, I; Van Den Abbeele, J; Vitouley, HS1
Adeyemi, OS; Sulaiman, FA1
Jia, P; Kuriakose, S; Muleme, HM; Onyilagha, C; Singh, R; Uzonna, JE1
Clausen, PH; Eisler, MC; McDermott, JJ; Mehlitz, D; Mitema, ES; Olila, D; Patzelt, RJ; Peregrine, AS; Poetzsch, CJ; Zessin, KH1
Gessner, A; Kayser, O; Müller, RH; Olbrich, C1
Bradley, B; de Felipe, C; Gettinby, G; Hunt, SP; Kennedy, PG; Leeman, SE; Murray, M; Rodgers, J1
BAUER, F1
WHITESIDE, EF1
HAWKING, F1
HUTCHINSON, MP; WATSON, HJ1
Jooste, R; Lumamba, D; Mubanga, J; Munsimbwe, L; Van den Bossche, P1
Anderson, LF; Barrett, MP; Burchmore, RJ; de Koning, HP; Stewart, M; Wallace, LJ1
Bauer, B; Clausen, PH; Gall, Y; McDermott, J; Mehlitz, D; Sidibe, I; Woitag, T1
Magona, JW; Mayende, JS; Okiria, R; Okuna, NM1
d'Ieteren, GD; McDermott, JJ; Mulatu, W; Nagda, SM; Rowlands, GJ; Schukken, YH; van Schaik, G1
Berkvens, D; Bos, J; Dhollander, S; Gaye, M; Geerts, S; Kora, S; Leak, S; Sanneh, M1
Anene, BM; Barrett, MP; Brock, JM; De Koning, HP; Ezeokonkwo, RC; Mmesirionye, TI; Tettey, JN1
Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L1
Akinwale, OP; Edeghere, HU; Esievo, KA; Nock, IH; Olukosi, YA1
Jamal, S; Macuamule, C; Marcotty, T; Neves, L; Penzhorn, BL; Sigauque, I; Van Den Bossche, P1
Batista, JS; Madruga, CR; Maia, TF; Riet-Correa, F; Simões, SD; Teixeira, MM1
Kagira, JM; Maina, N1
Burke, J; Eckersall, PD; Jennings, FW; Mburu, J; Mungatana, N; Murray, M; Ngure, RM1
Delespaux, V; Geerts, S; Geysen, D; Van den Bossche, P1
Gray, GD; Hajduk, SL; Jennings, FW1
Gray, GD; Jennings, FW; Whitelaw, DD1
Doyle, JJ; Jenni, L; Nantulya, VM1
Mansfield, JM; Sizemore, RC1
Dukes, P1
Abaru, DE; Isakina, D; Liwo, DA; Okori, EE1
Chumo, DA; Wellde, BT1
Küpper, W; Wolters, M1
Jennings, FW; Urquhart, GM1
Gilbert, RJ1
Craig, TM; Goodwin, JT; Logan, LL; Tembely, S1
Emerole, GO; Thabrew, MI1
Gray, GD; Jennings, FW1
Beckers, A; Gigase, P; Mulumba, P; Van Marck, EA; Wéry, M1
Akpavie, SO; Ikede, BO1
Gilbert, RJ; Newton, BA1
Joshua, RA1
Adam, SE; Elamin, EA; Homeida, AM; Mahmoud, MM1
Bernard, S; Guidot, G; Haase, M1
Jennings, FW; Miller, BM; Murray, PK; Urquhart, GM1
Boo, KS; Forsberg, CM; Mills, JN; Valli, VE1
Cagnolati, V; Mdachi, RE; Murilla, GA; Omukuba, JN1
Gettinby, G; Kemei, S; Mamman, M; Murphy, NB; Peregrine, AS1
Antia, RE; Egbe-Nwiyi, TN2
d'Ieteren, GD; Mulatu, W; Nagda, SM; Rowlands, GJ1
Gicheru, MM; Mwangi, EK; Sones, KR; Stevenson, P1
Mamman, M; Murphy, NB; Peregrine, AS; Williams, DJ1
Mabbott, NA; Sternberg, JM; Sutherland, IA1
Bruneel, H; Burke, J; Degroof, D; Molisho, D; Pépin, J; van den Eeckhout, A1
Burudi, EM; Majiwa, PA; Mbiuki, SM; Murphy, NB; Peregrine, AS1
Kinabo, LD1
Mamman, M; Peregrine, AS1
Gray, MA; Kimarua, RW; Peregrine, AS; Stevenson, P1
Kihurani, DO; Mbithi, PM; Mbiuki, SM; Mogoa, E; Nantulya, VM; Nguhiu-Mwangi, J1
Authié, E; d'Ieteren, GD; Leak, SG; Mulatu, W; Nagda, SM; Peregrine, AS; Rowlands, GJ1
Authié, E; Codjia, V; d'Ieteren, GD; Leak, SG; Majiwa, PA; Mulatu, W; Peregrine, AS; Rowlands, GJ1
Aliu, YO; Mamman, M; Peregrine, AS1
Milord, F; Pépin, J1
Mamman, M; Moloo, SK; Peregrine, AS1
Bacchi, CJ; Clarkson, AB; Goldberg, B; McCann, PP; Nathan, HC; Saric, M; Sjoerdsma, A; Yarlett, N1
Katende, J; Mamman, M; Moloo, SK; Peregrine, AS1
Anika, SM; Asuzu, IU; Odika, IE2
Logan-Henfrey, L; McOdimba, F; Mwangi, SM1
Agbe, A; Yielding, KL1
Bwangamoi, O; Joshua, RA; Mandebvu, E; Obwolo, MJ1
Chengmai, R; Fenqin, Z; Yongchun, O; Yongsheng, Y; Yuanguo, C1
Authié, E; Coulibaly, L; d'Ieteren, GD; Hecker, PA; Leak, SG; Rowlands, GJ1
Holmes, PH; Katunguka-Rwakishaya, E; Murray, M2
Majiwa, PA; Masake, R; Mulatu, W; Mulugeta, W; Peregrine, AS; Wilkes, J1
Diack, A; Moloo, SK; Peregrine, AS1
Burke, JM; Gichuki, CW; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M; Rodgers, J1
Enyaru, JC; Kaminsky, R; Lubega, GW; Matovu, E1
Gordon, JR; Kaushik, RS; Tabel, H; Uzonna, JE2
Bauer, B; Blankenburg, A; Clausen, PH; Leendertz, FH; Mehlitz, D; Sidibe, I; Tietjen, U1
Dolan, RB; Munga, L; Ndung'u, EK; Rossiter, PB; Stevenson, P1
Amsler-Delafosse, S; Bauer, B; Kaboré, I; Kamuanga, M1
Geerts, S; Goossens, B; Ndao, M; Osaer, S; Van Winghem, J1
Dávila, AM; Ortiz, AG; Pereira, SR; Ramirez, L; Silva, RA; Souza, SS1
Büscher, P; Faye, JA; Mattioli, RC1
d'Ieteren, GD; Leak, SG; Mulatu, W; Nagda, SM; Rowlands, GJ1
Abebe, G; Afewerk, Y; Clausen, PH; Mehlitz, D; Tilahun, G1
Bradley, B; Eckersall, PD; Gow, JW; Kennedy, PG; McComb, C; Murray, M; Rodgers, J1
Abebe, G; Assefa, E1
Williamson, J1
Lundin, LB; Mayor-Withey, KS; Morrison, WI; Pearson, TW; Roelants, GE1
Lohding, A; Staak, C1
Chizyuka, HG; Holmes, PH; Jennings, FW; Urquhart, GM; Whitelaw, DD1
Allonby, EW; Griffin, L1
Bacchi, CJ; Chunosoff, L; Hutner, SH; Moreira, R; Nathan, HC; Soto, KV1
Jennings, FW; Urquhart, GM; Whitelaw, DD1
Burke, J; Ruppol, JF1
Raether, W; Seidenath, H1
Clarkson, MJ; Edwards, G; Farrell, PJ; Penhale, WJ1
Abdel Karim, EI; Mohamed-Ahmed, MM; Rahman, AH1
Ainanshe, OA; Holmes, PH; Jennings, FW1
Löhr, KF; Maloo, SH; Mbura, RJ; Münstermann, S1
Bruijn, JA; Fleuren, GJ; van Leer, EH; van Velthuysen, ML1
Claxton, JR; Dwinger, RH; Leperre, P; Rawlings, P; Snow, WF1
Adams, JH; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M1
Bauer, B; Clausen, PH; Kaboré, I; Sidibe, I1
Arakawa, A; Chitambo, H; Ono, T1
Aliu, YO; Gray, MA; Mamman, M; Moloo, SK; Peregrine, AS; Silayo, RS1
Munyua, WK; Njogu, AR; Olaho-Mukani, W1
Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M1
Jennings, FW2
Kaminsky, R; Zweygarth, E2
Abatan, MO1
Egwu, GO; Onyeyili, PA; Orjiude, BA; Zaria, LT1
Onwualu, JE; Onyeyili, PA1
Arakawa, A; Chitambo, H1
Gettinby, G; McOdimba, FA; Moloo, SK; Murray, M; Paling, RW; Scott, JR1
Kutuza, SB; Moloo, SK1
Alushula, H; Dolan, RB; Mutugi, M; Njogu, AR; Okech, G; Sayer, PD; Stevenson, P1
Kaminsky, R; Webster, P; Zweygarth, E1
Ibitayo, AI; Knowles, G; Moloo, SK; Murphy, NB; Peregrine, AS; Scott, JR1
Hopkins, J; Luckins, AG; Mwangi, DM1
Anika, SM; Onyeyili, PA2
Lindqvist, KJ; Nantulya, VM1
Chumo, DA; Kamar, KK; Muriithi, RM; Njogu, AR; Onyango, F; Reardon, MJ; Roberts, LM; Wellde, BT1
Chumo, DA; Higgs, J; Kovatch, RM; Preston, JM; Wellde, BT1
Ibe, CC; Wosu, LO1
Chuma, F; Kaminsky, R; Zweygarth, E1
Rogers, DJ1
Jefferies, D; Jenni, L2
Brown, HC; Holmes, PH; Jennings, FW; Waitumbi, JN1
Lekaki, KA; Mbwambo, HA; Mella, PN1
Alushula, H; Gatuta, GM; Mgutu, SP; Njogu, AR; Wilson, AJ1
Malu, MN; Tabel, H1
Gardiner, PR; Murray, M; Whitelaw, DD1
Gardiner, PR; Moloo, SK; Nelson, RT; Vos, GJ1
Otesile, EB; Tabel, H1
Gardiner, PR; Moloo, SK; Vos, GJ1
Kaggwa, E; Mugera, GM; Munyua, WK1
Röttcher, D; Zweygarth, E1
Moloo, SK; Röttcher, D; Schönefeld, A1
Jenni, L; Moloo, SK; Paling, RW1
Abebe, G1
Bafort, JM; Molyneux, DH; Schmidt, H1
Büttner, M; Reiter, I; Seitz, A1
Reinwald, E; Risse, HJ; Takeya, M1
Dwinger, RH; Luckins, AG; Moloo, SK; Murray, M; Rae, P1
Dehoux, JP; Demey, F; Makumyaviri, AM; Verhulst, A1
Champalimaud, JL; Medina, EA; Ventura, FA1
Black, SJ; Koch, GL; Sendashonga, CN; Shapiro, SZ; Webster, P1
Akpavie, SO; Egbunike, GN; Ikede, BO1
Akol, GW; Murray, M1
Moulton, JE1
Mitchell, LA; Pearson, TW1
Urquhart, GM; Whitelaw, DD1
Bovell, D; Brighouse, G; Poltera, AA; Rudin, W; Sayer, PD1
Röttcher, D; Schillinger, D1
Dolan, RB; Njogu, AR; Sayer, PD; Wilson, AJ1

Reviews

5 review(s) available for diminazene and Trypanosomiasis, African

ArticleYear
Molecular tools for the rapid detection of drug resistance in animal trypanosomes.
    Trends in parasitology, 2008, Volume: 24, Issue:5

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

2008
Pharmacology of existing drugs for animal trypanosomiasis.
    Acta tropica, 1993, Volume: 54, Issue:3-4

    Topics: Animals; Arsenicals; Diminazene; Ethidium; Phenanthridines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosomiasis, African

1993
Pharmacology of diminazene: a review.
    Acta tropica, 1993, Volume: 54, Issue:3-4

    Topics: Animals; Animals, Domestic; Diminazene; Drug Resistance; Drug Therapy, Combination; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

1993
The treatment of human African trypanosomiasis.
    Advances in parasitology, 1994, Volume: 33

    Topics: Animals; Diminazene; Eflornithine; Humans; Melarsoprol; Nifurtimox; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

1994
Trypanosomiasis 'risk' or 'challenge': a review.
    Acta tropica, 1985, Volume: 42, Issue:1

    Topics: Africa, Eastern; Africa, Western; Animals; Cattle; Diminazene; Humans; Risk; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1985

Trials

11 trial(s) available for diminazene and Trypanosomiasis, African

ArticleYear
Probiotic administration enhanced antitrypanosomal effects of diminazene aceturate in dogs experimentally infected with
    Journal of complementary & integrative medicine, 2022, Sep-01, Volume: 19, Issue:3

    Topics: Animals; Diminazene; Dogs; Female; Hemoglobins; Male; Parasitemia; Probiotics; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2022
Resistance to trypanocidal drugs in cattle populations of Zambezia Province, Mozambique.
    Parasitology research, 2018, Volume: 117, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Mozambique; Phenanthridines; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2018
Effects of Trypanosoma brucei infection and diminazene aceturate therapy on testicular morphology and function of Nigerian local dogs.
    Veterinary parasitology, 2013, Sep-23, Volume: 196, Issue:3-4

    Topics: Animals; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Male; Nigeria; Parasitemia; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African

2013
Collateral benefits of restricted insecticide application for control of African trypanosomiasis on Theileria parva in cattle: a randomized controlled trial.
    Parasites & vectors, 2014, Sep-08, Volume: 7

    Topics: Animals; Cattle; Diminazene; Endemic Diseases; Female; Insecticides; Male; Pyrethrins; Theileria parva; Theileriasis; Trypanocidal Agents; Trypanosomiasis, African

2014
Effects of melarsamine hydrochloride (Cymelarsan) and diminazene aceturate (Berenil) on the pathology of experimental Trypanosoma brucei infection in red fronted gazelles (Gazella rufifrons).
    Veterinary parasitology, 2009, Jul-07, Volume: 163, Issue:1-2

    Topics: Animals; Antelopes; Arsenicals; Diminazene; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2009
Is trypanocidal drug resistance a threat for livestock health and production in endemic areas? Food for thoughts from Sahelian goats infected by Trypanosoma vivax in Bobo Dioulasso (Burkina Faso).
    Veterinary parasitology, 2012, Dec-21, Volume: 190, Issue:3-4

    Topics: Animals; Burkina Faso; Diminazene; Drug Resistance; Female; Goat Diseases; Goats; Hematocrit; Parasitemia; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African

2012
Susceptibility of West African Dwarf goats and WAD x Saanen crosses to experimental infection with Trypanosoma congolense.
    Veterinary parasitology, 2005, Jun-10, Volume: 130, Issue:1-2

    Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Body Weight; Crosses, Genetic; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Gambia; Genetic Predisposition to Disease; Goat Diseases; Goats; Hematocrit; Male; Microscopy, Phase-Contrast; Parasitemia; Trypanosoma congolense; Trypanosomiasis, African

2005
Comparison of isometamidium chloride and homidium bromide as prophylactic drugs for trypanosomiasis in cattle at Nguruman, Kenya.
    Acta tropica, 1995, Volume: 59, Issue:2

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Male; Phenanthridines; Seasons; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Weight Gain

1995
Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense.
    Research in veterinary science, 1995, Volume: 58, Issue:2

    Topics: Animals; Antibodies, Protozoan; Diminazene; Drug Resistance; Flow Cytometry; Goat Diseases; Goats; Male; Phenotype; Trypanosoma congolense; Trypanosomiasis, African

1995
Variation in sensitivity of Trypanosoma congolense to diminazene during the early phase of tsetse-transmitted infection in goats.
    Veterinary parasitology, 1993, Volume: 50, Issue:1-2

    Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Diminazene; Drug Administration Schedule; Drug Resistance; Goat Diseases; Goats; Injections, Intramuscular; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies

1993
The influence of supplementation with cotton seed cake on the resistance of Ugandan goats to primary and secondary challenges with Trypanosoma congolense and on their response to treatment.
    Veterinary parasitology, 1997, Volume: 70, Issue:1-3

    Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Diminazene; Food, Fortified; Goat Diseases; Goats; Hematocrit; Immunity, Innate; Male; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Uganda

1997

Other Studies

198 other study(ies) available for diminazene and Trypanosomiasis, African

ArticleYear
Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Acetates; Animals; Cells, Cultured; Esters; Humans; Mice; Molecular Structure; Myoblasts; Quinolines; Rats; Reactive Oxygen Species; Structure-Activity Relationship; Survival Rate; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2010
Conjugates of 2,4-Dihydroxybenzoate and Salicylhydroxamate and Lipocations Display Potent Antiparasite Effects by Efficiently Targeting the Trypanosoma brucei and Trypanosoma congolense Mitochondrion.
    Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4

    Topics: Cell Line; Drug Discovery; Humans; Hydroxybenzoates; Membrane Potential, Mitochondrial; Mitochondria; Salicylamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African

2017
Assessment of α-Cypermethrin Pour-On Application and Diminazene Aceturate for Treating Trypanosome-Related Diseases Caused by Tsetse Flies on Cattle in Mô, Togo.
    Journal of medical entomology, 2022, 03-16, Volume: 59, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Heteroptera; Pyrethrins; Togo; Trypanosoma; Trypanosomiasis, African; Tsetse Flies

2022
African trypanosome infection patterns in cattle in a farm setting in Southern Ghana.
    Acta tropica, 2023, Volume: 237

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Farms; Female; Ghana; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

2023
Trypanosoma Congolense Resistant to Trypanocidal Drugs Homidium and Diminazene and their Molecular Characterization in Lambwe, Kenya.
    Acta parasitologica, 2023, Volume: 68, Issue:1

    Topics: Animals; Cattle; Diminazene; Ethidium; Kenya; Mice; Phylogeny; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2023
Variation of sensitivity of Trypanosoma evansi isolates from Isiolo and Marsabit counties of Kenya to locally available trypanocidal drugs.
    PloS one, 2023, Volume: 18, Issue:2

    Topics: Animals; Camelus; Chlorides; Diminazene; Drug Resistance; Kenya; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

2023
Molecular identification of diminazene aceturate-resistant strains of Trypanosoma congolense in naturally infected domestic animals of Yoko in the centre region of Cameroon.
    Veterinary parasitology, regional studies and reports, 2020, Volume: 20

    Topics: Animals; Cameroon; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance; Sheep; Sheep Diseases; Sheep, Domestic; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2020
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence

2020
Diminazene resistance in Trypanosoma congolense is not caused by reduced transport capacity but associated with reduced mitochondrial membrane potential.
    Molecular microbiology, 2021, Volume: 116, Issue:2

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Folic Acid Transporters; Membrane Potential, Mitochondrial; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

2021
An ATP-Based Luciferase Viability Assay for Animal African Trypanosomes Using a 96-Well Plate.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1601

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Diminazene; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Luciferases; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African

2017
Parasitological and immunological evaluation of cattle experimentally infected with Trypanosoma vivax.
    Experimental parasitology, 2018, Volume: 185

    Topics: Adaptive Immunity; Animals; Antibodies, Protozoan; Biomarkers; Cattle; Cattle Diseases; Diminazene; Fluorescent Antibody Technique, Indirect; Immunity, Innate; Immunoglobulin G; Immunoglobulin M; Immunophenotyping; Leukocytes; Male; Parasitemia; Random Allocation; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African

2018
Effects of Trypanosoma brucei brucei infection and diminazene aceturate administration on the blood pressure, heart rate, and temperature of Wistar albino rats.
    Journal of basic and clinical physiology and pharmacology, 2018, Jun-27, Volume: 29, Issue:3

    Topics: Animals; Blood Pressure; Body Temperature; Diminazene; Heart Rate; Male; Rats; Rats, Wistar; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2018
Drug quality analysis of isometamidium chloride hydrochloride and diminazene diaceturate used for the treatment of African animal trypanosomosis in West Africa.
    BMC veterinary research, 2018, Nov-20, Volume: 14, Issue:1

    Topics: Africa, Western; Animals; Chromatography, High Pressure Liquid; Diminazene; Livestock; Phenanthridines; Quality Control; Trypanocidal Agents; Trypanosomiasis, African

2018
How rational drug use reduces trypanosome infections in cattle in chemo-resistance hot-spot villages of northern Togo.
    Acta tropica, 2019, Volume: 190

    Topics: Albendazole; Animals; Antimicrobial Stewardship; Cattle; Diminazene; Drug Resistance; Insecticides; Male; Phenanthridines; Ticks; Togo; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine

2019
Diminazene aceturate (Berenil) downregulates Trypanosoma congolense-induced proinflammatory cytokine production by altering phosphorylation of MAPK and STAT proteins.
    Immunologic research, 2019, Volume: 67, Issue:1

    Topics: Animals; Cattle; Cell Line, Transformed; Cytokines; Diminazene; Female; Humans; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2019
Sustaining Efforts of Controlling Zoonotic Sleeping Sickness in Uganda Using Trypanocidal Treatment and Spray of Cattle with Deltamethrin.
    Vector borne and zoonotic diseases (Larchmont, N.Y.), 2019, Volume: 19, Issue:8

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; Humans; Insect Vectors; Insecticides; Nitriles; Pyrethrins; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies; Uganda; Zoonoses

2019
Suspected resistance of Trypanosoma species to diminazene aceturate on a cattle farm in Nigeria.
    Tropical animal health and production, 2019, Volume: 51, Issue:7

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Intergenic; Drug Resistance; Farms; Nigeria; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

2019
In vitro anti-trypanosomal effects of selected phenolic acids on Trypanosoma brucei.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Animals; Cell Proliferation; Cell Survival; Deferoxamine; Diminazene; Drug Resistance; Gallic Acid; Humans; Hydroxybenzoates; Iron; Mitochondrial Membranes; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African

2019
Flavonoid mixture ameliorates increase in erythrocyte osmotic fragility and malondialdehyde concentration induced by Trypanosoma brucei brucei-infection in Wistar rats.
    Research in veterinary science, 2014, Volume: 96, Issue:1

    Topics: Animals; Diminazene; Diosmin; Erythrocytes; Male; Malondialdehyde; Osmotic Fragility; Parasitemia; Random Allocation; Rats; Rats, Wistar; Trypanosoma brucei brucei; Trypanosomiasis, African

2014
Kenyan purple tea anthocyanins and coenzyme-Q10 ameliorate post treatment reactive encephalopathy associated with cerebral human African trypanosomiasis in murine model.
    Parasitology international, 2014, Volume: 63, Issue:2

    Topics: Animals; Anthocyanins; Body Weight; Central Nervous System Diseases; Diminazene; Female; Hematocrit; Humans; Mice; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Ubiquinone

2014
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate.
    BMC veterinary research, 2014, Mar-10, Volume: 10

    Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2014
Evaluation of in vivo antitrypanosomal activity of crude extracts of Artemisia abyssinica against aTrypanosoma congolense isolate.
    BMC complementary and alternative medicine, 2014, Apr-01, Volume: 14

    Topics: Animals; Artemisia; Diminazene; Female; Humans; Male; Mice; Parasitemia; Phytotherapy; Plant Components, Aerial; Plant Extracts; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2014
Establishment of ATP-based luciferase viability assay in 96-well plate for Trypanosoma congolense.
    The Journal of veterinary medical science, 2014, Volume: 76, Issue:11

    Topics: Adenosine Triphosphate; Animals; Cell Division; Dimethyl Sulfoxide; Diminazene; High-Throughput Screening Assays; Inhibitory Concentration 50; Luciferases; Pentamidine; Species Specificity; Time Factors; Trypanosoma congolense; Trypanosomiasis, African

2014
Effect of diminazene aceturate, levamisole and vitamin C combination therapy in rats experimentally infected with Trypanosoma brucei brucei.
    Asian Pacific journal of tropical medicine, 2014, Volume: 7, Issue:6

    Topics: Animals; Ascorbic Acid; Body Temperature; Body Weight; Diminazene; Drug Therapy, Combination; Hemoglobins; Leukocyte Count; Levamisole; Male; Parasite Load; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2014
Improvements on restricted insecticide application protocol for control of Human and Animal African Trypanosomiasis in eastern Uganda.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:10

    Topics: Albendazole; Animals; Cattle; Cattle Diseases; Diminazene; Female; Humans; Insect Control; Insecticides; Male; Population Density; Trypanosomiasis, African; Uganda

2014
PCR and microsatellite analysis of diminazene aceturate resistance of bovine trypanosomes correlated to knowledge, attitude and practice of livestock keepers in South-Western Ethiopia.
    Acta tropica, 2015, Volume: 146

    Topics: Agriculture; Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Ethiopia; Health Knowledge, Attitudes, Practice; Livestock; Longitudinal Studies; Microsatellite Repeats; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2015
In vivo experimental drug resistance study in Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia.
    Acta tropica, 2015, Volume: 146

    Topics: Animals; Cattle; Cattle Diseases; Communicable Diseases; Diminazene; Drug Resistance; Ethiopia; Insect Vectors; Male; Parasitemia; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Tsetse Flies

2015
Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments.
    Parasite immunology, 2015, Volume: 37, Issue:9

    Topics: Animals; B-Lymphocyte Subsets; Bone Marrow; Diminazene; Female; Lymphopoiesis; Mice; Mice, Inbred C57BL; Spleen; Suramin; Trypanocidal Agents; Trypanosomiasis; Trypanosomiasis, African

2015
Novel trypanocide from an extract of Pleurotus sajor-caju against Trypanosoma congolense.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Biomarkers; Body Weight; Diminazene; Disease Models, Animal; Dose-Response Relationship, Drug; Mice, Inbred BALB C; Parasitemia; Pleurotus; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2017
IgM, lgG and IL-6 profiles in the Trypanosoma brucei brucei monkey model of human African trypanosomiasis.
    Acta tropica, 2017, Volume: 168

    Topics: Animals; Antigens, Protozoan; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Immunoglobulin G; Immunoglobulin M; Interleukin-6; Trypanosoma brucei brucei; Trypanosomiasis, African

2017
Trypanosomiasis challenge estimation using the diminazene aceturate (Berenil) index in Zebu in Gabon.
    Tropical animal health and production, 2017, Volume: 49, Issue:3

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Gabon; Longitudinal Studies; Rain; Seasons; Tropical Climate; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine

2017
Cattle breeding, trypanosomosis prevalence and drug resistance in Northern Togo.
    Veterinary parasitology, 2017, Mar-15, Volume: 236

    Topics: Animals; Breeding; Cattle; Cattle Diseases; Communicable Disease Control; Cross-Sectional Studies; Diminazene; Drug Resistance; Phenanthridines; Prevalence; Togo; Treatment Failure; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African; Trypanosomiasis, Bovine

2017
Five-fold increase in Trypanosoma congolense isolates resistant to diminazene aceturate over a seven-year period in Eastern Zambia.
    Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2008, Volume: 11, Issue:6

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Protozoan; Dose-Response Relationship, Drug; Drug Resistance; Mice; Mice, Inbred Strains; Polymorphism, Restriction Fragment Length; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zambia

2008
Immunospecific immunoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys.
    Tropical medicine & international health : TM & IH, 2009, Volume: 14, Issue:7

    Topics: Animals; Antigens, Protozoan; Biomarkers; Brain; Chlorocebus aethiops; Diminazene; Female; Immunoglobulin G; Immunoglobulin M; Interleukin-10; Male; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2009
Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.
    The American journal of tropical medicine and hygiene, 2009, Volume: 81, Issue:4

    Topics: Animals; Diminazene; Humans; Indicators and Reagents; Oxazines; Pentamidine; Sensitivity and Specificity; Sphingosine; Staining and Labeling; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Xanthenes

2009
Development of a nanoparticulate formulation of diminazene to treat African trypanosomiasis.
    Nanotechnology, 2010, Dec-17, Volume: 21, Issue:50

    Topics: Animals; Diminazene; Drug Delivery Systems; Drug Stability; Mice; Nanoparticles; Oxidation-Reduction; Phospholipids; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2010
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense.
    Acta tropica, 2011, Volume: 119, Issue:1

    Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2011
Genital lesions in male red fronted gazelles (Gazella rufifrons) experimentally infected with Trypanosoma brucei and the effect of melarsamine hydrochloride (Cymelarsan®) and diminazene aceturate (Berenil®) in its treatment.
    Theriogenology, 2011, Sep-01, Volume: 76, Issue:4

    Topics: Animals; Antelopes; Arsenicals; Body Temperature; Diminazene; Genital Diseases, Male; Hematocrit; Histocytochemistry; Male; Parasitemia; Semen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2011
Highly debilitating natural Trypanosoma vivax infections in Brazilian calves: epidemiology, pathology, and probable transplacental transmission.
    Parasitology research, 2012, Volume: 110, Issue:1

    Topics: Animals; Antiprotozoal Agents; Brazil; Cattle; Cattle Diseases; Diminazene; Infectious Disease Transmission, Vertical; Parasitemia; Prevalence; Severity of Illness Index; Survival Analysis; Trypanosoma vivax; Trypanosomiasis, African

2012
The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats.
    Asian Pacific journal of tropical medicine, 2011, Volume: 4, Issue:5

    Topics: Animals; Azadirachta; Diminazene; Drug Resistance; Drug Therapy, Combination; Female; Male; Parasitemia; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Trypanosoma brucei brucei; Trypanosomiasis, African

2011
Improved PCR-RFLP for the detection of diminazene resistance in Trypanosoma congolense under field conditions using filter papers for sample storage.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:7

    Topics: Animals; Blood Specimen Collection; Cattle; Cattle Diseases; Diminazene; DNA, Protozoan; Drug Resistance; Paper; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2011
High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:12

    Topics: Africa South of the Sahara; Alleles; Animals; Antiprotozoal Agents; Diminazene; Disease Models, Animal; DNA, Protozoan; Drug Resistance; Mice; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Selection, Genetic; Trypanosoma congolense; Trypanosomiasis, African

2011
Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso.
    Veterinary parasitology, 2012, Jun-08, Volume: 187, Issue:1-2

    Topics: Animals; Burkina Faso; Cattle; Cross-Sectional Studies; Diminazene; Longitudinal Studies; Phenanthridines; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine

2012
Investigation of the antitrypanosomal activity of Buchholzia coriacea seed extract against a field strain of Trypanosoma congolense.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2011, Volume: 8, Issue:5 Suppl

    Topics: Administration, Oral; Animals; Capparaceae; Diminazene; Dose-Response Relationship, Drug; Female; Hematocrit; Male; Methanol; Mice; Parasitemia; Phytotherapy; Plant Extracts; Seeds; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2011
Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali.
    Parasites & vectors, 2012, Aug-01, Volume: 5

    Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Mali; Phenanthridines; Rural Population; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies

2012
Biochemical and morphological changes in Trypanosoma brucei brucei-infected rats treated with homidium chloride and diminazene aceturate.
    Journal of basic and clinical physiology and pharmacology, 2012, Volume: 23, Issue:4

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Diminazene; Ethidium; Male; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2012
Diminazene aceturate (Berenil) modulates the host cellular and inflammatory responses to Trypanosoma congolense infection.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Cytokines; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Forkhead Transcription Factors; Immunity, Cellular; Inflammation; Interleukin-2 Receptor alpha Subunit; Kupffer Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Spleen; T-Lymphocytes; Trypanosoma congolense; Trypanosomiasis, African

2012
Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda.
    Acta tropica, 2002, Volume: 84, Issue:1

    Topics: Animals; Cattle; Diminazene; Disease Models, Animal; Drug Resistance; Ethidium; Female; Goat Diseases; Goats; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda

2002
Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate.
    Journal of drug targeting, 2002, Volume: 10, Issue:5

    Topics: Blood-Brain Barrier; Diminazene; Drug Carriers; Drug Compounding; Drug Stability; Humans; Lipids; Microspheres; Nanotechnology; Particle Size; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Trypanocidal Agents; Trypanosomiasis, African

2002
Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice.
    Brain : a journal of neurology, 2003, Volume: 126, Issue:Pt 7

    Topics: Animals; Diminazene; Disease Models, Animal; Hippocampus; Meningoencephalitis; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Trypanosomiasis, African

2003
[Trypanosomiasis and babesiasis in Africa and their treatment with the new preparation berenil].
    Zeitschrift fur Tropenmedizin und Parasitologie, 1955, Volume: 6, Issue:2

    Topics: Africa; Amidines; Aniline Compounds; Animals; Apicomplexa; Babesiosis; Cattle; Cattle Diseases; Coloring Agents; Diminazene; Dog Diseases; Dogs; Infections; Trypanosomiasis; Trypanosomiasis, African

1955
A strain of Trypanosoma congolense directly resistant to berenil.
    Journal of comparative pathology, 1963, Volume: 73

    Topics: Animals; Antiparasitic Agents; Azo Compounds; Diminazene; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African

1963
DRUG-RESISTANCE OF TRYPANOSOMA CONGOLENSE AND OTHER TRYPANOSOMES TO QUINAPYRAMINE, PHENANTHRIDINES, BERENIL AND OTHER COMPOUNDS IN MICE.
    Annals of tropical medicine and parasitology, 1963, Volume: 57

    Topics: Animals; Antiprotozoal Agents; Diminazene; Mice; Phenanthridines; Quinolines; Quinolinium Compounds; Research; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African

1963
Berenil in the treatment of Trypanosoma gambiense infection in man.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1962, Volume: 56

    Topics: Amidines; Aniline Compounds; Animals; Black People; Diminazene; Humans; Trypanosoma brucei gambiense; Trypanosomiasis; Trypanosomiasis, African

1962
A large-scale trial to evaluate the efficacy of a 1% pour-on formulation of cyfluthrin (Cylence, Bayer) in controlling bovine trypanosomosis in Eastern Zambia.
    Tropical animal health and production, 2004, Volume: 36, Issue:1

    Topics: Administration, Topical; Animals; Cattle; Diminazene; Hematocrit; Incidence; Insecticides; Nitriles; Pyrethrins; Seasons; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Zambia

2004
The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:5

    Topics: Adenosine; Animals; Biological Transport, Active; Diminazene; Drug Resistance; Female; Kinetics; Mutation; Nucleoside Transport Proteins; Rats; Rats, Wistar; Saccharomyces cerevisiae; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2004
Trypanocidal failure suggested by PCR results in cattle field samples.
    Acta tropica, 2004, Volume: 92, Issue:1

    Topics: Animals; Cattle; Diminazene; Drug Resistance, Microbial; Parasitic Sensitivity Tests; Phenanthridines; Polymerase Chain Reaction; Sensitivity and Specificity; Treatment Failure; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine

2004
Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda.
    The Onderstepoort journal of veterinary research, 2004, Volume: 71, Issue:3

    Topics: Animals; Cattle; Diminazene; Female; Insect Control; Male; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Uganda

2004
Transition models to assess risk factors for new and persistent trypanosome infections in cattle-analysis of longitudinal data from the Ghibe Valley, southwest Ethiopia.
    The Journal of parasitology, 2004, Volume: 90, Issue:6

    Topics: Age Factors; Animals; Cattle; Diminazene; Ethiopia; Female; Incidence; Insect Control; Insect Vectors; Longitudinal Studies; Male; Models, Biological; Odds Ratio; Prevalence; Recurrence; Risk Factors; Seasons; Sensitivity and Specificity; Sex Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

2004
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.
    Parasitology, 2006, Volume: 132, Issue:Pt 1

    Topics: Animals; Diminazene; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Female; Parasitic Sensitivity Tests; Pentamidine; Random Allocation; Rats; Recurrence; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2006
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:2

    Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2006
Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection.
    Veterinary parasitology, 2006, Apr-30, Volume: 137, Issue:3-4

    Topics: Animals; Diminazene; Disease Susceptibility; Goat Diseases; Goats; Male; Nigeria; Parasitemia; Random Allocation; Treatment Outcome; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African

2006
The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride.
    The Onderstepoort journal of veterinary research, 2005, Volume: 72, Issue:4

    Topics: Animals; Diminazene; Drug Resistance; Ethidium; Mice; Mozambique; Parasitic Sensitivity Tests; Phenanthridines; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2005
Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system.
    Veterinary parasitology, 2007, Jan-31, Volume: 143, Issue:2

    Topics: Abortion, Veterinary; Animals; Antibodies, Protozoan; Brain; Brazil; Cattle; Cattle Diseases; Diminazene; Disease Outbreaks; Female; Nervous System; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African

2007
Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients.
    The Onderstepoort journal of veterinary research, 2007, Volume: 74, Issue:1

    Topics: Animals; Diminazene; Drug Resistance, Multiple; Humans; Kenya; Melarsoprol; Mice; Parasitic Sensitivity Tests; Phenanthridines; Random Allocation; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda

2007
Acute phase response in mice experimentally infected with Trypanosoma congolense: a molecular gauge of parasite-host interaction.
    Veterinary parasitology, 2008, Jan-25, Volume: 151, Issue:1

    Topics: Acute-Phase Proteins; Acute-Phase Reaction; Anemia; Animals; Diminazene; Disease Models, Animal; Female; Haptoglobins; Hematocrit; Host-Parasite Interactions; Mice; Random Allocation; Serum Amyloid P-Component; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2008
Relapse of monomorphic and pleomorphic Trypanosoma brucei infections in the mouse after chemotherapy.
    Zeitschrift fur Parasitenkunde (Berlin, Germany), 1982, Volume: 67, Issue:2

    Topics: Amidines; Animals; Brain; Diminazene; Female; Mice; Recurrence; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African

1982
Chemotherapy of Trypanosoma brucei in mice with diminazene aceturate. Variation in the aparasitaemic period over 5 years.
    Zeitschrift fur Parasitenkunde (Berlin, Germany), 1982, Volume: 67, Issue:3

    Topics: Amidines; Animals; Blood; Diminazene; Freezing; Mice; Preservation, Biological; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African

1982
Studies on Trypanosoma (nannomonas) congolense IV. Experimental immunization of mice against tsetse fly challenge.
    Parasitology, 1980, Volume: 80, Issue:1

    Topics: Animals; Diminazene; Epitopes; Female; Immunization; Insect Bites and Stings; Mice; Trypanosoma; Trypanosomiasis, African; Tsetse Flies

1980
Lymphocyte function in experimental African trypanosomiasis. VII. Loss of antigen-nonspecific suppressor-T-cell activity.
    Cellular immunology, 1984, Volume: 87, Issue:2

    Topics: Animals; Antibody Formation; Antigens, Ly; Diminazene; Immune Tolerance; Male; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes, Regulatory; Trypanosoma; Trypanosomiasis, African

1984
Arsenic and old taxa: subspeciation and drug sensitivity in Trypanosoma brucei.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:6

    Topics: Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Isoenzymes; Male; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1984
Retrospective long-term study of effects of berenil by follow-up of patients treated since 1965.
    Tropenmedizin und Parasitologie, 1984, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Amidines; Cerebrospinal Fluid; Child; Child, Preschool; Diminazene; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Trypanocidal Agents; Trypanosomiasis, African; Uganda; Urine

1984
Persistence of Berenil in cattle.
    Tropical animal health and production, 1983, Volume: 15, Issue:3

    Topics: Amidines; Animals; Cattle; Diminazene; Kenya; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine

1983
Observation on drug resistance of Trypanosoma (Nannomonas) congolense and Trypanosoma (Duttonella) vivax in cattle at a feedlot in the Northern Ivory Coast.
    Tropenmedizin und Parasitologie, 1983, Volume: 34, Issue:3

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Male; Phenanthridines; Quaternary Ammonium Compounds; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1983
The use of the 2 substituted 5-nitroimidazole, Fexinidazole (Hoe 239) in the treatment of chronic T. brucei infections in mice.
    Zeitschrift fur Parasitenkunde (Berlin, Germany), 1983, Volume: 69, Issue:5

    Topics: Animals; Antiprotozoal Agents; Chronic Disease; Diminazene; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1983
Studies in rabbits on the disposition and trypanocidal activity of the anti-trypanosomal drug, diminazene aceturate (Berenil).
    British journal of pharmacology, 1983, Volume: 80, Issue:1

    Topics: Amidines; Animals; Diminazene; Kinetics; Rabbits; Tissue Distribution; Trypanosomiasis, African

1983
Maintaining zebu Maure cattle in a tsetse infested area of Mali.
    Tropical animal health and production, 1984, Volume: 16, Issue:1

    Topics: Animals; Body Weight; Cattle; Diminazene; Female; Male; Mali; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1984
Response of the rat's hepatic drug-metabolizing enzyme system to chemotherapy of Trypanosoma b. brucei infections with Berenil and Suramin.
    Enzyme, 1984, Volume: 31, Issue:3

    Topics: Amidines; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Diminazene; Female; Glutamate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Liver; Microsomes, Liver; Phospholipids; Rats; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African

1984
Relapsed parasitaemia following chemotherapy of chronic T. brucei infections in mice and its relation to cerebral trypanosomes.
    Contributions to microbiology and immunology, 1983, Volume: 7

    Topics: Animals; Antiprotozoal Agents; Brain; Chronic Disease; Diminazene; Mice; Recurrence; Trypanosoma brucei brucei; Trypanosomiasis, African

1983
Studies of choroid plexus involvement in chronic infections of mice with Trypanosoma brucei gambiense.
    Contributions to microbiology and immunology, 1983, Volume: 7

    Topics: Animals; Antiprotozoal Agents; Choroid Plexus; Chronic Disease; Diminazene; Mice; Nifurtimox; Trypanosoma brucei brucei; Trypanosomiasis, African

1983
Delay in resolution of trypanosome-induced genital lesions in male rabbits infected with Trypanosoma brucei and treated with diminazene aceturate.
    Research in veterinary science, 1982, Volume: 32, Issue:3

    Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Genital Diseases, Male; Genitalia, Male; Male; Rabbits; Scrotum; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African

1982
Pharmacokinetics and efficacy of the trypanocide diminazene aceturate (Berenil) in rabbits.
    The Veterinary record, 1982, Oct-23, Volume: 111, Issue:17

    Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Kinetics; Rabbits; Trypanosomiasis, African

1982
Diminazene aceturate in the treatment of experimentally induced Trypanosoma brucei brucei infection in domestic chickens.
    The Veterinary record, 1982, Nov-20, Volume: 111, Issue:21

    Topics: Amidines; Animals; Antiprotozoal Agents; Chickens; Diminazene; Humans; Mice; Poultry Diseases; Trypanosoma brucei brucei; Trypanosomiasis, African

1982
The efficacy of berenil (diminazene aceturate) against Trypanosoma evansi infection in mice.
    Journal of veterinary pharmacology and therapeutics, 1982, Volume: 5, Issue:4

    Topics: Amidines; Animals; Antiprotozoal Agents; Blood; Diminazene; Female; Male; Mice; Mice, Inbred Strains; Species Specificity; Trypanosoma; Trypanosomiasis, African

1982
Trypanosomiasis in Zebu cattle. Reappearance of Trypanosoma congolense in brain tissue after treatment with Berenil.
    Revue d'elevage et de medecine veterinaire des pays tropicaux, 1981, Volume: 34, Issue:2

    Topics: Africa, Western; Amidines; Animals; Brain; Cattle; Diminazene; Female; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine

1981
'Berenil' and nitroimidazole combinations in the treatment of Trypanosoma brucei infection with central nervous system involvement.
    International journal for parasitology, 1980, Volume: 10, Issue:1

    Topics: Amidines; Animals; Benzamidines; Central Nervous System Diseases; Diminazene; Ethidium; Female; Isoxazoles; Mice; Nitroimidazoles; Phenanthridines; Ronidazole; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1980
The quantitation of trypanosoma congolense in calves. III. A quantitative comparison of trypanosomes in jugular vein and microvasculature and tests of dispersing agents.
    Tropenmedizin und Parasitologie, 1980, Volume: 31, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Capillaries; Cattle; Dexamethasone; Diminazene; Jugular Veins; Liver; Male; Muscles; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine

1980
Disposition of diminazene aceturate (Berenil) in trypanosome-infected pregnant and lactating cows.
    Veterinary parasitology, 1995, Volume: 58, Issue:3

    Topics: Animals; Animals, Suckling; Cattle; Diminazene; Female; Lactation; Milk; Pregnancy; Pregnancy Complications, Parasitic; Tissue Distribution; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1995
Frequency of diminazene-resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene aceturate.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:5

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Mice; Trypanosoma congolense; Trypanosomiasis, African; Whole-Body Irradiation

1995
Use of monoclonal antibodies for detecting T brucei brucei infection in splenectomised dogs.
    The Journal of small animal practice, 1995, Volume: 36, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Male; Splenectomy; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

1995
Variations in packed red cell volume and trypanosome prevalence and relationships with reproductive traits in east African Zebu cows exposed to drug-resistant trypanosomes.
    Acta tropica, 1995, Volume: 59, Issue:2

    Topics: Abortion, Veterinary; Animals; Cattle; Diminazene; Drug Resistance; Ethiopia; Female; Hematocrit; Incidence; Lactation; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Reproduction; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine

1995
Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivo.
    Parasite immunology, 1995, Volume: 17, Issue:3

    Topics: Animals; Antiprotozoal Agents; Apoptosis; Diminazene; DNA Damage; Female; Immune Tolerance; Immunotherapy, Adoptive; Lymphocyte Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Nitric Oxide; Spleen; T-Lymphocytes; Trypanosoma brucei brucei; Trypanosomiasis, African

1995
[Control of Trypanosoma gambiense trypanosomiasis. Evaluation of a strategy based on the treatment of serologically suspected cases with a single dose of diminazene].
    Annales de la Societe belge de medecine tropicale, 1994, Volume: 74, Issue:3

    Topics: Agglutination Tests; Democratic Republic of the Congo; Diminazene; Humans; Incidence; Melarsoprol; Trypanosomiasis, African

1994
Response of diminazene-resistant and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occurring as a mixed infection in goats.
    Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:6

    Topics: Animals; Base Sequence; Diminazene; DNA, Protozoan; Drug Resistance; Goat Diseases; Goats; Molecular Sequence Data; Polymerase Chain Reaction; Trypanosoma congolense; Trypanosomiasis, African

1994
Drug sensitivity screening in vitro of populations of Trypanosoma congolense originating from cattle and tsetse flies at Nguruman, Kenya.
    Acta tropica, 1993, Volume: 55, Issue:1-2

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1993
Trypanosoma brucei, T. congolense and T. vivax infections in horses on a farm in Kenya.
    Tropical animal health and production, 1994, Volume: 26, Issue:2

    Topics: Animals; Diminazene; Disease Outbreaks; Horse Diseases; Horses; Kenya; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African

1994
Epidemiology of bovine trypanosomiasis in the Ghibe valley, southwest Ethiopia. 2. Factors associated with variations in trypanosome prevalence, incidence of new infections and prevalence of recurrent infections.
    Acta tropica, 1993, Volume: 53, Issue:2

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethiopia; Female; Male; Prevalence; Recurrence; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1993
Epidemiology of bovine trypanosomiasis in the Ghibe valley, southwest Ethiopia. 3. Occurrence of populations of Trypanosoma congolense resistant to diminazene, isometamidium and homidium.
    Acta tropica, 1993, Volume: 53, Issue:2

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Ethiopia; Phenanthridines; Species Specificity; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1993
Comparative pharmacokinetics of diminazene in noninfected Boran (Bos indicus) cattle and Boran cattle infected with Trypanosoma congolense.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5

    Topics: Acute Disease; Animals; Cattle; Chronic Disease; Diminazene; Female; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1993
Relapse of Trypanosoma congolense infection in goats after diminazene aceturate is not a result of invasion of the central nervous system.
    Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:1

    Topics: Animals; Diminazene; Goat Diseases; Goats; Male; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

1994
Combination chemotherapy of drug-resistant Trypanosoma brucei rhodesiense infections in mice using DL-alpha-difluoromethylornithine and standard trypanocides.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3

    Topics: Animals; Arsenicals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Eflornithine; Female; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

1994
The effect of trypanocidal drug treatment on the haematological changes in Trypanosoma brucei brucei infected splenectomised dogs.
    Veterinary parasitology, 1993, Volume: 50, Issue:1-2

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Diminazene; Dog Diseases; Dogs; Erythrocyte Count; Erythrocyte Indices; Female; Hematocrit; Hemoglobins; Leukocyte Count; Male; Reticulocytes; Splenectomy; Trypanosoma brucei brucei; Trypanosomiasis, African

1993
The chemotherapeutic efficacy of diminazene aceturate and lithium chloride against relapse infection of Trypanosoma brucei brucei in rats.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1995, Volume: 46, Issue:2

    Topics: Animals; Blood-Brain Barrier; Dexamethasone; Diminazene; Drug Therapy, Combination; Female; Lithium Chloride; Male; Parasitemia; Rats; Rats, Wistar; Recurrence; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1995
The effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations.
    Acta tropica, 1995, Volume: 59, Issue:4

    Topics: Acute-Phase Reaction; Animals; Diminazene; Hematocrit; Iron; Leukocyte Count; Male; Rabbits; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Zinc

1995
Kinetoplasts play an important role in the drug responses of Trypanosoma brucei.
    The Journal of parasitology, 1995, Volume: 81, Issue:6

    Topics: Acriflavine; Animals; Azides; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Ethidium; Female; Light; Mice; Mitochondria; Mitoguazone; Mutation; Parasitemia; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1995
The effects of hyperosmolar agents lithium chloride and sucrose on the brain concentration of diminazene aceturate in rats.
    Acta tropica, 1995, Volume: 60, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain; Diminazene; Female; Lithium Chloride; Male; Permeability; Rats; Rats, Wistar; Sucrose; Tissue Distribution; Trypanocidal Agents; Trypanosomiasis, African

1995
Resistance to diminazine aceturate by Trypanosoma congolense from cattle in the Zambezi Valley of Zimbabwe.
    Veterinary parasitology, 1995, Volume: 60, Issue:1-2

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zimbabwe

1995
Trypanocidal value of liposomal diminazene in experimental Trypanosoma brucei evansi infection in mice.
    Veterinary parasitology, 1996, Volume: 61, Issue:3-4

    Topics: Animals; Diminazene; Drug Carriers; Guinea Pigs; Liposomes; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1996
Effect of tsetse control on trypanosome prevalence in livestock: problems of experimental design and statistical interpretation--a case study in northern Côte d'Ivoire.
    Veterinary parasitology, 1996, Volume: 63, Issue:3-4

    Topics: Animal Husbandry; Animals; Cattle; Cote d'Ivoire; Diminazene; Insect Control; Insect Vectors; Sheep; Sheep Diseases; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1996
Susceptibility of three breeds of Ugandan goats to experimental infection with Trypanosoma congolense.
    Tropical animal health and production, 1997, Volume: 29, Issue:1

    Topics: Anemia; Animals; Body Weight; Breeding; Diminazene; Disease Susceptibility; Goat Diseases; Goats; Growth Disorders; Incidence; Male; Parasitemia; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Uganda

1997
Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia.
    Acta tropica, 1997, Apr-15, Volume: 64, Issue:3-4

    Topics: Animals; Biological Assay; Cattle; Chromosomes; Diminazene; Drug Resistance, Microbial; Drug Resistance, Multiple; Ethidium; Ethiopia; Karyotyping; Mice; Microbial Sensitivity Tests; Phenanthridines; Rats; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

1997
Effect of diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense in Glossina morsitans centralis.
    Veterinary parasitology, 1997, Volume: 70, Issue:1-3

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Goats; Insect Vectors; Male; Mice; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1997
The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis.
    Neuropathology and applied neurobiology, 1997, Volume: 23, Issue:3

    Topics: Animals; Brain; Brain Diseases; Diminazene; Eflornithine; Female; Mice; Mice, Inbred Strains; Polyamines; Putrescine; Trypanocidal Agents; Trypanosomiasis, African

1997
Response of a T. b. rhodesiense stock with reduced drug susceptibility in vitro to treatment in mice and cattle.
    Acta tropica, 1998, Volume: 69, Issue:3

    Topics: Animals; Cattle; Diminazene; DNA, Protozoan; Drug Resistance; Male; Mice; Phenanthridines; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda

1998
Immunoregulation in experimental murine Trypanosoma congolense infection: anti-IL-10 antibodies reverse trypanosome-mediated suppression of lymphocyte proliferation in vitro and moderately prolong the lifespan of genetically susceptible BALB/c mice.
    Parasite immunology, 1998, Volume: 20, Issue:6

    Topics: Animals; Diminazene; Disease Susceptibility; Female; Interleukin-10; Life Expectancy; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; T-Lymphocytes; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

1998
A drug incubation Glossina infectivity test (DIGIT) to assess the susceptibility of Trypanosoma congolense bloodstream forms to trypanocidal drugs (Xenodiagnosis).
    Acta tropica, 1999, Jan-15, Volume: 72, Issue:1

    Topics: Animals; Diminazene; Drug Resistance, Multiple; Goat Diseases; Goats; Insect Vectors; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies

1999
Cytokines and antibody responses during Trypanosoma congolense infections in two inbred mouse strains that differ in resistance.
    Parasite immunology, 1999, Volume: 21, Issue:2

    Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cytokines; Diminazene; Epitopes, B-Lymphocyte; Female; Immunity, Innate; Interferon-gamma; Interleukin-10; Interleukin-4; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; Spleen; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma

1999
Rinderpest vaccination and the incidence and development of trypanosomosis in cattle.
    Tropical animal health and production, 1999, Volume: 31, Issue:2

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Hematocrit; Incidence; Insect Vectors; Kenya; Male; Neutralization Tests; Rinderpest; Rinderpest virus; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Vaccination; Viral Vaccines

1999
Improvement of cattle productivity through rapid alleviation of African animal trypanosomosis by integrated disease management practices in the agropastoral zone of Yalé, Burkina Faso.
    Tropical animal health and production, 1999, Volume: 31, Issue:2

    Topics: Animals; Burkina Faso; Cattle; Diminazene; Female; Hematocrit; Humans; Insect Control; Insect Vectors; Insecticides; Interviews as Topic; Milk; Nitriles; Pregnancy; Pyrethrins; Seasons; Sentinel Surveillance; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1999
The susceptibility of Djallonké and Djallonké-Sahelian crossbred sheep to Trypanosoma congolense and helminth infection under different diet levels.
    Veterinary parasitology, 1999, Aug-16, Volume: 85, Issue:1

    Topics: Animal Feed; Animals; Anthelmintics; Antibodies, Protozoan; Antiprotozoal Agents; Crosses, Genetic; Diminazene; Disease Susceptibility; Feces; Female; Fenbendazole; Gambia; Helminthiasis, Animal; Helminths; Hematocrit; Male; Nutritional Status; Parasite Egg Count; Parasitemia; Random Allocation; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African

1999
Hematology of natural bovine trypanosomosis in the Brazilian Pantanal and Bolivian wetlands.
    Veterinary parasitology, 1999, Aug-16, Volume: 85, Issue:1

    Topics: Abortion, Veterinary; Anemia, Hypochromic; Anemia, Macrocytic; Animals; Bolivia; Brazil; Cattle; Diarrhea; Diminazene; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Leukocyte Count; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine

1999
Susceptibility of N'Dama cattle to experimental challenge and cross-species superchallenges with bloodstream forms of Trypanosoma congolense and T. vivax.
    Veterinary parasitology, 1999, Sep-30, Volume: 86, Issue:2

    Topics: Animals; Cattle; Diminazene; Disease Susceptibility; Gambia; Hematocrit; Male; Parasitemia; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Weight Gain

1999
Estimating the effects of tsetse control on livestock productivity--a case study in southwest Ethiopia.
    Tropical animal health and production, 1999, Volume: 31, Issue:5

    Topics: Administration, Topical; Animals; Body Weight; Cattle; Diminazene; Drug Resistance; Ectoparasitic Infestations; Ethiopia; Female; Hematocrit; Insecticides; Male; Prevalence; Pyrethrins; Regression Analysis; Seasons; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1999
Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia.
    Acta tropica, 2000, Oct-02, Volume: 76, Issue:3

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Ethiopia; Mice; Mice, Inbred BALB C; Parasitemia; Phenanthridines; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2000
Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice.
    Parasitology international, 2001, Volume: 50, Issue:1

    Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Cytokines; Diminazene; Disease Models, Animal; Encephalitis; Female; Haptoglobins; Mice; Parasitemia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Amyloid P-Component; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2001
Drug-resistant Trypanosoma congolense in naturally infected donkeys in north Omo Zone, southern Ethiopia.
    Veterinary parasitology, 2001, Aug-31, Volume: 99, Issue:4

    Topics: Animals; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Equidae; Ethiopia; Female; Male; Mice; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

2001
Chemotherapy of African trypanosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1976, Volume: 70, Issue:2

    Topics: Arsenicals; Diminazene; Humans; Suramin; Triazines; Trypanocidal Agents; Trypanosomiasis, African

1976
Immune depression in trypanosome-infected mice. IV. Kinetics of suppression and alleviation by the trypanocidal drug Berenil.
    Clinical and experimental immunology, 1979, Volume: 37, Issue:3

    Topics: Amidines; Animals; Diminazene; Female; Fluorescent Antibody Technique; Immunity; Immunosuppression Therapy; Kinetics; Leukocyte Count; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Mice; Mice, Inbred Strains; Mitogens; Spleen; T-Lymphocytes, Regulatory; Time Factors; Trypanosomiasis, African

1979
The complement fixation test and African trypanosomiasis: I. Experimental infection and re-infection in cattle before and after treatment.
    Tropenmedizin und Parasitologie, 1979, Volume: 30, Issue:1

    Topics: Animals; Antibodies; Antibody Specificity; Cattle; Complement Fixation Tests; Diminazene; Male; Recurrence; Time Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine

1979
The brain as a source of relapsing Trypanosoma brucei infection in mice after chemotherapy.
    International journal for parasitology, 1979, Volume: 9, Issue:4

    Topics: Amidines; Animals; Brain; Diminazene; Female; Mice; Trypanosoma brucei brucei; Trypanosomiasis, African

1979
The economic effects of trypanosomiasis in sheep and goats at a range research station in Kenya.
    Tropical animal health and production, 1979, Volume: 11, Issue:3

    Topics: Animals; Benzamides; Diminazene; Goats; Kenya; Phenanthridines; Sheep; Sheep Diseases; Trypanosomiasis, African

1979
Curative effects of the antipiroplasms amicarbalide and imidocarb on Trypanosoma brucei infection in mice.
    The Journal of protozoology, 1979, Volume: 26, Issue:4

    Topics: Amidines; Animals; Carbanilides; Chemical Phenomena; Chemistry; Diminazene; Female; Imidocarb; Male; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1979
The relationship between duration of infection with Trypanosoma brucei in mice and the efficacy of chemotherapy.
    Parasitology, 1977, Volume: 75, Issue:2

    Topics: Amidines; Animals; Diminazene; Drug Resistance, Microbial; Ethidium; Female; Mice; Recurrence; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1977
[Follow-up study of therapy of trypanosomiasis in Kimpangu (Republic of Zaire)].
    Annales de la Societe belge de medecine tropicale, 1977, Volume: 57, Issue:4-5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diminazene; Drug Evaluation; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nitrofurans; Oxazoles; Trypanocidal Agents; Trypanosomiasis, African

1977
Trypanocidal effect of diamidine 98/202 in experimental Trypanosoma rhodesiense infection of the stumptailed macaque (Macaca arctoides).
    Tropenmedizin und Parasitologie, 1976, Volume: 27, Issue:2

    Topics: Amidines; Animals; Blood-Brain Barrier; Cerebrospinal Fluid; Diminazene; Drug Resistance, Microbial; Female; Haplorhini; Macaca; Male; Microbial Sensitivity Tests; Pentamidine; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

1976
Serum protein changes in cattle infected with Trypanosoma vivax.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1975, Volume: 69, Issue:1

    Topics: Animals; Antibodies; Blood Proteins; Cattle; Cattle Diseases; Diminazene; Immunoglobulin G; Immunoglobulin M; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine

1975
Multiple drug-resistant bovine trypanosomes in South Darfur Province, Sudan.
    Tropical animal health and production, 1992, Volume: 24, Issue:3

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Phenanthridines; Sudan; Time Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine

1992
Isolation of drug-resistant strains of Trypanosoma congolense from the lower Shabelle region of southern Somalia.
    Tropical animal health and production, 1992, Volume: 24, Issue:2

    Topics: Animals; Animals, Domestic; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Recurrence; Somalia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1992
Trypanosomiasis control in Boran cattle in Kenya: a comparison between chemoprophylaxis and a parasite detection and intravenous treatment method using isometamidium chloride.
    Tropical animal health and production, 1992, Volume: 24, Issue:1

    Topics: Animals; Cattle; Diminazene; Drug Administration Schedule; Female; Injections, Intramuscular; Injections, Intravenous; Kenya; Male; Phenanthridines; Risk Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine

1992
Pathogenesis of trypanosomiasis-induced glomerulonephritis in mice.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1992, Volume: 7, Issue:6

    Topics: Animals; Antibodies; Basement Membrane; Diminazene; Female; Glomerulonephritis; Kidney Glomerulus; Mice; Mice, Inbred BALB C; Trypanosomiasis, African

1992
Trypanosomiasis in cattle in Gambia: incidence, prevalence and tsetse challenge.
    Acta tropica, 1992, Volume: 50, Issue:3

    Topics: Animals; Breeding; Cattle; Diminazene; Female; Gambia; Incidence; Insect Vectors; Male; Prevalence; Regression Analysis; Seasons; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1992
Subcurative chemotherapy and fatal post-treatment reactive encephalopathies in African trypanosomiasis.
    Lancet (London, England), 1992, Apr-18, Volume: 339, Issue:8799

    Topics: Adolescent; Adult; Animals; Arsenicals; Brain; Brain Diseases; Child; Child, Preschool; Diminazene; Female; Humans; Male; Mice; Nitroimidazoles; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1992
Development of multiple drug resistance of Trypanosoma congolense in Zebu cattle under high natural tsetse fly challenge in the pastoral zone of Samorogouan, Burkina Faso.
    Acta tropica, 1992, Volume: 51, Issue:3-4

    Topics: Animals; Burkina Faso; Cattle; Diminazene; Drug Resistance; Prevalence; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1992
In vivo assessment of drug sensitivity of African trypanosomes using the akinetoplastic induction test.
    Research in veterinary science, 1992, Volume: 52, Issue:2

    Topics: Animals; Cattle; Diminazene; Mice; Phenanthridines; Rosaniline Dyes; Staining and Labeling; Toluidines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1992
Response of Trypanosoma congolense in goats to single and double treatment with diminazene aceturate.
    Research in veterinary science, 1992, Volume: 53, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Diminazene; Drug Administration Schedule; Goat Diseases; Goats; Hematocrit; Lymph Nodes; Male; Skinfold Thickness; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

1992
An enzyme-linked immunosorbent assay (ELISA) for the detection of trypanosomal antigens in goat serum using a monoclonal antibody.
    Journal of immunoassay, 1992, Volume: 13, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Diminazene; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Goats; Immunoglobulin M; Sensitivity and Specificity; Trypanosoma brucei brucei; Trypanosomiasis, African

1992
The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis.
    Neuropathology and applied neurobiology, 1992, Volume: 18, Issue:6

    Topics: Animals; Azathioprine; Brain Diseases; Diminazene; Disease Models, Animal; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosomiasis, African

1992
Chemotherapy of CNS-trypanosomiasis: the combined use of diminazene aceturate or pentamidine with DL-alpha-difluoromethylornithine (DFMO).
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1992, Volume: 43, Issue:2

    Topics: Animals; Arsenicals; Central Nervous System Diseases; Diminazene; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Mice; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1992
Evaluation of DL-alpha-difluoromethylornithine against susceptible and drug-resistant Trypanosoma brucei brucei.
    Acta tropica, 1991, Volume: 48, Issue:3

    Topics: Animals; Arsenicals; Culture Media; Diminazene; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Humans; Immune Sera; Male; Mice; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1991
The effect of verapamil alone and in combination with trypanocides on multidrug-resistant Trypanosoma brucei brucei.
    Acta tropica, 1991, Volume: 49, Issue:3

    Topics: Animals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Female; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Verapamil

1991
Combination therapy of trypanosomiasis using diminazene and non-steroidal anti-inflammatory drugs.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diminazene; Drug Therapy, Combination; Mice; Phenylpropionates; Rabbits; Trypanosomiasis, African

1991
DL-alpha-difluoromethylornithine (DFMO)-Berenil combination: therapeutic and prophylactic activity against Trypanosoma brucei brucei infection in mice.
    Revue d'elevage et de medecine veterinaire des pays tropicaux, 1991, Volume: 44, Issue:4

    Topics: Animals; Diminazene; Drug Therapy, Combination; Eflornithine; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1991
Efficacy of combination of DFMO and diminazene aceturate in the treatment of late stage Trypanosoma brucei brucei infection in rats.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:2

    Topics: Animals; Brain Diseases; Diminazene; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Male; Rats; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1991
Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle.
    Veterinary parasitology, 1991, Volume: 39, Issue:1-2

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Zambia

1991
Susceptibility of N'Dama and Boran cattle to sequential challenges with tsetse-transmitted clones of Trypanosoma congolense.
    Parasite immunology, 1991, Volume: 13, Issue:4

    Topics: Anemia; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Body Weight; Cattle; Diminazene; Disease Susceptibility; Female; Hematocrit; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1991
Expression of resistance to isometamidium and diminazene in Trypanosoma congolense in Boran cattle infected by Glossina morsitans centralis.
    Acta tropica, 1990, Volume: 47, Issue:2

    Topics: Amidines; Animals; Cattle; Diminazene; Disease Reservoirs; Drug Resistance; Goats; Insect Vectors; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1990
Homidium bromide as a chemoprophylactic for cattle trypanosomiasis in Kenya.
    Acta tropica, 1990, Volume: 47, Issue:3

    Topics: Animals; Cattle; Diminazene; Ethidium; Hematocrit; Kenya; Male; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Weight Gain

1990
Trypanosoma brucei evansi: dyskinetoplasia and loss of infectivity after long-term in vitro cultivation.
    Acta tropica, 1990, Volume: 48, Issue:2

    Topics: Animals; Diminazene; DNA, Circular; DNA, Kinetoplast; Female; Male; Mice; Microscopy, Electron; Phenanthridines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1990
Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense.
    Parasitology, 1991, Volume: 102 Pt 1

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Genetic Variation; Isoenzymes; Mice; Phenanthridines; Phenotype; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1991
Cellular phenotypes in Trypanosoma congolense infected sheep: the local skin reaction.
    Parasite immunology, 1990, Volume: 12, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Diminazene; Immunophenotyping; Lymphocyte Subsets; Sheep; Sheep Diseases; Skin; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

1990
Effects of the combination of DL-alpha-difluoromethylornithine and diminazene aceturate in Trypanosoma congolense infection of dogs.
    Veterinary parasitology, 1990, Volume: 37, Issue:1

    Topics: Animals; Diminazene; Dog Diseases; Dogs; Drug Therapy, Combination; Eflornithine; Female; Male; Trypanosoma congolense; Trypanosomiasis, African

1990
Antigen-detection enzyme immunoassays for the diagnosis of Trypanosoma vivax, T. congolense and T. brucei infections in cattle.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1989, Volume: 40, Issue:3

    Topics: Animals; Antigen-Antibody Complex; Antigens, Protozoan; Cattle; Diminazene; Enzyme-Linked Immunosorbent Assay; Time Factors; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1989
Natural and acquired resistance to Trypanosoma vivax in cattle.
    Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1

    Topics: Animals; Cattle; Diminazene; Gastrointestinal Hemorrhage; Goats; Immunity, Active; Immunity, Innate; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1989
Trypanosoma congolense: erythrocyte indices, plasma iron turnover and effects of treatment in infected cattle.
    Annals of tropical medicine and parasitology, 1989, Volume: 83 Suppl 1

    Topics: Anemia, Hemolytic; Animals; Cattle; Cattle Diseases; Diminazene; Erythrocyte Count; Erythrocyte Indices; Hematocrit; Iron; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1989
Use of extracts of Picralima nitida bark in the treatment of experimental trypanosomiasis: a preliminary study.
    Journal of ethnopharmacology, 1989, Volume: 25, Issue:3

    Topics: Animals; Diminazene; Drug Evaluation, Preclinical; Female; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1989
The influence of Trypanosoma congolense infection on the disposition kinetics of diminazene aceturate in the dog.
    Veterinary research communications, 1989, Volume: 13, Issue:3

    Topics: Amidines; Animals; Diminazene; Dog Diseases; Dogs; Injections, Intravenous; Male; Regression Analysis; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

1989
Trypanosoma brucei brucei: expression of drug resistance in vitro.
    Experimental parasitology, 1989, Volume: 69, Issue:3

    Topics: Amidines; Animals; Diminazene; Drug Resistance; Female; Male; Mice; Phenanthridines; Species Specificity; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1989
The effect of trypanocidal drugs on the transmission of Trypanosoma brucei brucei by Glossina morsitans centralis.
    Acta tropica, 1987, Volume: 44, Issue:1

    Topics: Animals; Diminazene; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tsetse Flies

1987
The effect of the trypanocidal drugs berenil and samorin on infections of Glossina morsitans centralis by Trypanosoma congolense.
    Acta tropica, 1987, Volume: 44, Issue:3

    Topics: Amidines; Animals; Diminazene; Insect Vectors; Male; Mice; Mice, Inbred ICR; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies

1987
The relapse of Trypanosoma brucei brucei infections after chemotherapy in rabbits.
    Acta tropica, 1988, Volume: 45, Issue:1

    Topics: Amidines; Animals; Diminazene; Female; Male; Mice; Rabbits; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African

1988
Berenil (diminazene aceturate)-resistant Trypanosoma congolense in cattle under natural tsetse challenge at Kibaha, Tanzania.
    Acta tropica, 1988, Volume: 45, Issue:3

    Topics: Amidines; Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Tanzania; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine

1988
A simple epidemiological method for animal trypanosomiasis to provide relevant data for effective financial decision-making.
    Veterinary parasitology, 1986, Volume: 20, Issue:4

    Topics: Age Factors; Animals; Body Weight; Cattle; Cost-Benefit Analysis; Diminazene; Female; Kenya; Male; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1986
The alternative pathway of complement in sheep during the course of infection with Trypanosoma congolense and after Berenil treatment.
    Parasite immunology, 1986, Volume: 8, Issue:3

    Topics: Animals; Antibodies, Bacterial; Brucella abortus; Complement Activation; Complement C3; Complement Factor B; Complement Pathway, Alternative; Diminazene; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African

1986
Extravascular foci of Trypanosoma vivax in goats: the central nervous system and aqueous humor of the eye as potential sources of relapse infections after chemotherapy.
    Parasitology, 1988, Volume: 97 ( Pt 1)

    Topics: Animals; Aqueous Humor; Central Nervous System Diseases; Cerebrospinal Fluid; Choroid Plexus; Diminazene; Goats; Male; Mice; Recurrence; Trypanosoma; Trypanosomiasis, African

1988
Attempts to protect goats against challenge with Trypanosoma vivax by initiation of primary infections with large numbers of metacyclic trypanosomes.
    Parasitology, 1988, Volume: 97 ( Pt 3)

    Topics: Animals; Antibodies, Protozoan; Diminazene; Goats; Male; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies

1988
Enhanced resistance of highly susceptible Balb/c mice to infection with Trypanosoma congolense after infection and cure.
    The Journal of parasitology, 1987, Volume: 73, Issue:5

    Topics: Agglutination Tests; Animals; Antibodies, Protozoan; Antigenic Variation; Diminazene; Female; Fluorescent Antibody Technique; Immune Sera; Immunity, Active; Immunization, Passive; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rabbits; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African

1987
Susceptibility of goats to tsetse-transmitted challenge with Trypanosoma vivax from East and West Africa.
    Parasitology, 1988, Volume: 96 ( Pt 1)

    Topics: Africa, Eastern; Africa, Western; Animals; Chronic Disease; Diminazene; Disease Susceptibility; Goats; Immunity, Active; Insect Vectors; Male; Recurrence; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies; Virulence

1988
Relapses in dogs experimentally infected with Trypanosoma brucei and treated with diminazene aceturate or isometamidium chloride.
    Veterinary parasitology, 1988, Volume: 27, Issue:3-4

    Topics: Alanine Transaminase; Amidines; Animals; Antibodies, Protozoan; Aspartate Aminotransferases; Diminazene; Dog Diseases; Dogs; Fever; Hematocrit; Hemoglobins; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1988
The treatment of Trypanosoma (Nannomonas) simiae in pigs with diminazene aceturate in combination with a 5-substituted 2-nitroimidazole compound (Ro 15-0216).
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1987, Volume: 38, Issue:3

    Topics: Acetanilides; Amidines; Animals; Diminazene; Drug Therapy, Combination; Female; Male; Mice; Nitroimidazoles; Swine; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African

1987
The sensitivity to trypanocidal drugs of Trypanosoma vivax isolated in Kenya and Somalia.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1987, Volume: 38, Issue:3

    Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Male; Phenanthridines; Quinolinium Compounds; Somalia; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine

1987
Trypanosoma congolense: host responses following tsetse transmitted infection of Kilifi isolates in goats.
    Experimental parasitology, 1987, Volume: 63, Issue:3

    Topics: Animals; Antibody Formation; Antigens, Protozoan; Cattle; Diminazene; Glucose-6-Phosphate Isomerase; Goats; Isoenzymes; Kenya; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1987
Failure of berenil therapy to eliminate early infections with a strain of Trypanosoma brucei from West Abaya, Ethiopia.
    Tropical animal health and production, 1987, Volume: 19, Issue:1

    Topics: Amidines; Animals; Cattle; Diminazene; Ethiopia; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Trypanosomiasis, Bovine

1987
Effect of tetracycline administration on the efficacy of diminazene aceturate therapy and prophylaxis in Trypanosoma brucei infections of mice.
    Research in veterinary science, 1987, Volume: 43, Issue:2

    Topics: Amidines; Animals; Diminazene; Drug Therapy, Combination; Mice; Oxytetracycline; Rolitetracycline; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1987
Development of Trypanosoma brucei in suckling mouse brain following intracerebral injection.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81, Issue:3

    Topics: Animals; Animals, Suckling; Brain; Diminazene; Injections, Intraventricular; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1987
Trypanosoma theileri Laveran, 1902, in naturally and experimentally infected cattle: parasite isolation, serological and cellular reactions and Berenil sensitivity.
    Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1987, Volume: 34, Issue:5

    Topics: Amidines; Animals; Antibodies, Protozoan; Cattle; Diminazene; Immunity, Cellular; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine

1987
Pathobiochemical alterations in experimental chronic and acute trypanosomal infection in mice.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1987, Volume: 25, Issue:10

    Topics: Alkaline Phosphatase; Amidines; Animals; Aspartate Aminotransferases; Blood Cell Count; Blood Proteins; Diminazene; Erythrocytes; Female; Isoenzymes; L-Lactate Dehydrogenase; Leukocyte Count; Mice; Time Factors; Trypanosoma congolense; Trypanosomiasis, African

1987
Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse.
    Parasite immunology, 1986, Volume: 8, Issue:4

    Topics: Animals; Antibody Formation; Diminazene; Goats; Male; Neutralization Tests; Skin; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies

1986
[Duration of the preventive action of diminazene aceturate on experimental infection of NMRI mice with metacyclic forms of Trypanosoma brucei brucei].
    Annales de la Societe belge de medecine tropicale, 1986, Volume: 66, Issue:2

    Topics: Amidines; Animals; Diminazene; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1986
Computer-assisted tomographic findings in a patient with African trypanosomiasis.
    The Journal of tropical medicine and hygiene, 1986, Volume: 89, Issue:2

    Topics: Brain Diseases; Child, Preschool; Diminazene; Humans; Male; Melarsoprol; Meningoencephalitis; Recurrence; Tomography, X-Ray Computed; Trypanosomiasis, African

1986
Regulation of parasite-specific antibody responses in resistant (C57BL/6) and susceptible (C3H/HE) mice infected with Trypanosoma (trypanozoon) brucei brucei.
    Parasite immunology, 1986, Volume: 8, Issue:5

    Topics: Animals; Antibody Formation; Antibody-Producing Cells; Diminazene; Disease Susceptibility; Female; Immune Tolerance; Immunity, Innate; Immunoglobulins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Electron; Spleen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1986
Ejaculate characteristics of sheep infected with Trypanosoma brucei and T vivax: changes caused by treatment with diminazene aceturate.
    Research in veterinary science, 1987, Volume: 42, Issue:1

    Topics: Animals; Diminazene; Male; Semen; Sheep; Sheep Diseases; Sperm Count; Sperm Motility; Spermatozoa; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African

1987
Induction of protective immunity in cattle by tsetse-transmitted cloned isolates of Trypanosoma congolense.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:6

    Topics: Animals; Antibody Formation; Cattle; Diminazene; Female; Hypersensitivity; Male; Mice; Mice, Inbred A; Neutralization Tests; Skin; Skin Tests; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1985
Relapse infection after chemotherapy in goats experimentally infected with Trypanosoma brucei: pathological changes in central nervous system.
    Veterinary pathology, 1986, Volume: 23, Issue:1

    Topics: Amidines; Animals; Blood-Brain Barrier; Central Nervous System; Choroiditis; Diminazene; Goats; Male; Meningitis; Orchiectomy; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1986
Antibody responses in resistant and susceptible inbred mice infected with Trypanosoma congolense.
    Immunology, 1986, Volume: 57, Issue:2

    Topics: Animals; Antibody Specificity; Antigens, Protozoan; Antigens, Surface; Diminazene; Disease Susceptibility; Female; Glycoproteins; Immunity, Innate; Immunoglobulin G; Immunoglobulin M; Male; Membrane Proteins; Mice; Mice, Inbred A; Mice, Inbred C57BL; Rats; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma

1986
Maternally derived immunity in young mice to infection with Trypanosoma brucei and its potentiation by Berenil chemotherapy.
    Parasite immunology, 1985, Volume: 7, Issue:3

    Topics: Age Factors; Amidines; Animals; Animals, Suckling; Colostrum; Diminazene; Female; Immunization, Passive; Mice; Pregnancy; Trypanosoma brucei brucei; Trypanosomiasis, African

1985
Immunopathological aspects of trypanosomal meningoencephalitis in vervet monkeys after relapse following Berenil treatment.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1985, Volume: 79, Issue:4

    Topics: Amidines; Animals; Antigen-Antibody Complex; Autoantibodies; Blood-Brain Barrier; Brain; Chlorocebus aethiops; Diminazene; Immunoglobulin G; Immunoglobulin M; Meningoencephalitis; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1985
Multiple drug resistance in Trypanosoma vivax in the Tana River District of Kenya.
    The Veterinary record, 1985, Nov-23, Volume: 117, Issue:21

    Topics: Animals; Cattle; Diminazene; Drug Resistance, Microbial; Ethidium; Kenya; Phenanthridines; Quinolinium Compounds; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine

1985
Trypanotolerance in East African Orma Boran cattle.
    The Veterinary record, 1985, Dec-14, Volume: 117, Issue:24

    Topics: Animals; Cattle; Cattle Diseases; Diminazene; Immunity; Kenya; Male; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies

1985