diminazene aceturate has been researched along with Trypanosomiasis, African in 171 studies
*Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals. [MeSH]
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 55 (32.16) | 18.7374 |
1990's | 52 (30.41) | 18.2507 |
2000's | 21 (12.28) | 29.6817 |
2010's | 36 (21.05) | 24.3611 |
2020's | 7 (4.09) | 2.80 |
Authors | Studies |
---|---|
Cerami, A; Ulrich, P | 1 |
Barrett, MP; Brun, R; Dardonville, C; Kaiser, M; Tanious, F; Wilson, WD | 1 |
Buckner, FS; Creason, SA; Gelb, MH; Gillespie, JR; Herbst, ZM; Hulverson, MA; McQueen, J; Patrick, DA; Ranade, RM; Tidwell, RR | 1 |
Bacchi, CJ; Braillard, S; Chatelain, E; Denny, WA; Gaukel, E; Launay, D; Maes, L; Marshall, AJ; Mowbray, CE; Thompson, AM; Wring, SA; Yarlett, N | 1 |
Comini, MA; Franco, J; Scarone, L | 1 |
Balabadi, D; Essodina, T; Martin Bienvenu, S; Soudah, B; Toï, N; Wendemanegde Ernest, S; Yao, L | 1 |
Erin, JP; Kolawole, BJ; Nwoha, RIO; Orakpoghenor, O | 1 |
Ekloh, W; Gwira, TM; Sunter, JD | 1 |
Alusi, PM; Auma, JE; Chemuliti, JK; Kurgat, RK; Mdachi, RE; Mugunieri, LG; Mukiria, PW; Ogolla, KO; Okoth, SO; Wamwiri, FN; Wanjala, KB | 1 |
Farikou, O; Kamga, RMN; Magang, MEK; Mewamba, EM; Ravel, S; Simo, G; Tiofack, AAZ; Tume, C | 1 |
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK | 1 |
Inoue, N; Molefe, NI; Suganuma, K | 1 |
Adeleye, AI; Adeleye, OE; Adeyemi, SO; Ale, JM; Durotoye, LA; Olukunle, JO; Sogebi, EOA | 1 |
Adam, Y; Bayala, B; Belem, AMG; Bengaly, Z; Cecchi, G; Delespaux, V; Sidibé, I; Somda, MB; Têko-Agbo, A; Van Den Abbeele, J; Vitouley, SH; Zongo, A | 1 |
Batawui, K; Bauer, B; Clausen, PH; Delespaux, V; Den Abbeele, JV; Hoppenheit, A; Kulo, AE; Tchamdja, E | 1 |
Jia, P; Kuriakose, SM; Onyilagha, C; Singh, R; Uzonna, JE | 1 |
Waiswa, C; Wangoola, MR | 1 |
Ademola, IO; Macleod, ET; Odeniran, PO; Welburn, SC | 1 |
Adjimani, JP; Amisigo, CM; Antwi, CA; Gwira, TM | 1 |
Ezeh, IO; Ezeokonkwo, RC; Idika, IK; Iheagwam, CN; Obi, CF; Obidike, RI; Omoja, VU | 1 |
Aluwong, T; Ambali, SF; Ayo, JO; Kobo, PI; Maikai, V; Zezi, AU | 1 |
Isaac, AO; Nyariki, JN; Rashid, K; Wachira, FN | 1 |
Asres, K; Bisrat, D; Terefe, G; Tewabe, Y | 1 |
Feyera, T; Shibeshi, W; Terefe, G | 1 |
Chekwube, AI; Ezeokonkwo, RC; Ikenna, UE; Onyema, EI | 1 |
Hatendorf, J; Kabasa, JD; Muhanguzi, D; Picozzi, K; Thrusfield, M; Waiswa, C; Welburn, SC | 2 |
De Deken, R; Delespaux, V; Duchateau, L; Moti, Y; Thys, E; Van Den Abbeele, J | 1 |
Abebe, G; Barry, D; Dagnachew, S; Goddeeris, B; McCulloch, R; Terefe, G | 1 |
Bockstal, V; Cnops, J; De Trez, C; Magez, S; Miquel, MC; Radwanska, M | 1 |
Ademola, IO; Odeniran, PO | 1 |
Gachie, BM; Kagira, JM; Karanja, SM; Maina, NW; Maranga, DN; Ngotho, M; Waema, MW | 1 |
Adjahoutonon, B; Cossic, BGA; Dibanganga, GL; Gloaguen, P; Leroy, P; MacLeod, ET; Maganga, G; Picozzi, K | 1 |
Adomefa, K; Bankolé, AA; Batawui, K; Cecchi, G; Clausen, PH; De Deken, R; Delespaux, V; Hoppenheit, A; Kulo, AE; Marcotty, T; Tchamdja, E; Van Den Abbeele, J; Vitouley, HS | 1 |
Delespaux, V; Dinka, H; Geerts, S; Masumu, J; Van den Bossche, P | 1 |
Aliyu, MM; Ibrahim, UI; Mbaya, AW; Nwosu, CO; Taiwo, VO | 1 |
Farah, IO; Hau, J; Jensen, HE; Kagira, JM; Karanja, SM; Ngotho, M | 1 |
Farah, IO; Hau, J; Kagira, JM; Kariuki, C; Maina, N; Mwangangi, DM; Ngotho, M; Thuita, JK | 1 |
Kumshe, HA; Mbaya, AW; Nwosu, CO | 1 |
Batista, JS; Bezerra, FS; Câmara, AC; García, HA; Olinda, RG; Rebouças, RE; Rodrigues, CM; Silva, TM; Teixeira, MM; Vale, RG | 1 |
Anaga, AO; Anika, SM; Asuzu, IU; Ihedioha, TE; Mhomga, LI; Obidike, IR; Omoja, VU; Umeakuana, PU | 1 |
Chitanga, S; Delespaux, V; Marcotty, T; Namangala, B; Van Den Abbeele, J; Van den Bossche, P | 1 |
Akoda, GK; Bengaly, Z; De Deken, R; Delespaux, V; Diallo, A; Marcotty, T; Nebié, RL; Ouédraogo, M; Séré, M; Sidibé, I; Sow, A; Van Den Abbeele, J; Van den Bossche, P; Vitouley, HS | 1 |
Anene, BM; Asuzu, IU; Nweze, NE | 1 |
Allegye-Cudjoe, E; Bauer, B; Boucoum, Z; Clausen, PH; Diall, O; Diarra, B; Mungube, EO; Randolph, T; Sanogo, Y; Vitouley, HS; Zessin, KH | 1 |
Bengaly, Z; Delespaux, V; Marcotty, T; Sidibe, I; Van Den Abbeele, J; Vitouley, HS | 1 |
Adeyemi, OS; Sulaiman, FA | 1 |
Jia, P; Kuriakose, S; Muleme, HM; Onyilagha, C; Singh, R; Uzonna, JE | 1 |
Clausen, PH; Eisler, MC; McDermott, JJ; Mehlitz, D; Mitema, ES; Olila, D; Patzelt, RJ; Peregrine, AS; Poetzsch, CJ; Zessin, KH | 1 |
Gessner, A; Kayser, O; Müller, RH; Olbrich, C | 1 |
BAUER, F | 1 |
WHITESIDE, EF | 1 |
HAWKING, F | 1 |
HUTCHINSON, MP; WATSON, HJ | 1 |
Jooste, R; Lumamba, D; Mubanga, J; Munsimbwe, L; Van den Bossche, P | 1 |
Anderson, LF; Barrett, MP; Burchmore, RJ; de Koning, HP; Stewart, M; Wallace, LJ | 1 |
Bauer, B; Clausen, PH; Gall, Y; McDermott, J; Mehlitz, D; Sidibe, I; Woitag, T | 1 |
Magona, JW; Mayende, JS; Okiria, R; Okuna, NM | 1 |
d'Ieteren, GD; McDermott, JJ; Mulatu, W; Nagda, SM; Rowlands, GJ; Schukken, YH; van Schaik, G | 1 |
Anene, BM; Barrett, MP; Brock, JM; De Koning, HP; Ezeokonkwo, RC; Mmesirionye, TI; Tettey, JN | 1 |
Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L | 1 |
Akinwale, OP; Edeghere, HU; Esievo, KA; Nock, IH; Olukosi, YA | 1 |
Jamal, S; Macuamule, C; Marcotty, T; Neves, L; Penzhorn, BL; Sigauque, I; Van Den Bossche, P | 1 |
Batista, JS; Madruga, CR; Maia, TF; Riet-Correa, F; Simões, SD; Teixeira, MM | 1 |
Kagira, JM; Maina, N | 1 |
Burke, J; Eckersall, PD; Jennings, FW; Mburu, J; Mungatana, N; Murray, M; Ngure, RM | 1 |
Gray, GD; Hajduk, SL; Jennings, FW | 1 |
Gray, GD; Jennings, FW; Whitelaw, DD | 1 |
Mansfield, JM; Sizemore, RC | 1 |
Abaru, DE; Isakina, D; Liwo, DA; Okori, EE | 1 |
Chumo, DA; Wellde, BT | 1 |
Küpper, W; Wolters, M | 1 |
Jennings, FW; Urquhart, GM | 1 |
Gilbert, RJ | 1 |
Craig, TM; Goodwin, JT; Logan, LL; Tembely, S | 1 |
Emerole, GO; Thabrew, MI | 1 |
Gray, GD; Jennings, FW | 1 |
Beckers, A; Gigase, P; Mulumba, P; Van Marck, EA; Wéry, M | 1 |
Akpavie, SO; Ikede, BO | 1 |
Gilbert, RJ; Newton, BA | 1 |
Joshua, RA | 1 |
Adam, SE; Elamin, EA; Homeida, AM; Mahmoud, MM | 1 |
Jennings, FW; Miller, BM; Murray, PK; Urquhart, GM | 1 |
Boo, KS; Forsberg, CM; Mills, JN; Valli, VE | 1 |
Cagnolati, V; Mdachi, RE; Murilla, GA; Omukuba, JN | 1 |
Antia, RE; Egbe-Nwiyi, TN | 2 |
d'Ieteren, GD; Mulatu, W; Nagda, SM; Rowlands, GJ | 1 |
Mamman, M; Murphy, NB; Peregrine, AS; Williams, DJ | 1 |
Mabbott, NA; Sternberg, JM; Sutherland, IA | 1 |
Mamman, M; Peregrine, AS | 1 |
Gray, MA; Kimarua, RW; Peregrine, AS; Stevenson, P | 1 |
Kihurani, DO; Mbithi, PM; Mbiuki, SM; Mogoa, E; Nantulya, VM; Nguhiu-Mwangi, J | 1 |
Mamman, M; Moloo, SK; Peregrine, AS | 1 |
Bacchi, CJ; Clarkson, AB; Goldberg, B; McCann, PP; Nathan, HC; Saric, M; Sjoerdsma, A; Yarlett, N | 1 |
Katende, J; Mamman, M; Moloo, SK; Peregrine, AS | 1 |
Anika, SM; Asuzu, IU; Odika, IE | 2 |
Logan-Henfrey, L; McOdimba, F; Mwangi, SM | 1 |
Agbe, A; Yielding, KL | 1 |
Bwangamoi, O; Joshua, RA; Mandebvu, E; Obwolo, MJ | 1 |
Authié, E; Coulibaly, L; d'Ieteren, GD; Hecker, PA; Leak, SG; Rowlands, GJ | 1 |
Diack, A; Moloo, SK; Peregrine, AS | 1 |
Holmes, PH; Katunguka-Rwakishaya, E; Murray, M | 1 |
Burke, JM; Gichuki, CW; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M; Rodgers, J | 1 |
Enyaru, JC; Kaminsky, R; Lubega, GW; Matovu, E | 1 |
Gordon, JR; Kaushik, RS; Tabel, H; Uzonna, JE | 2 |
Dolan, RB; Munga, L; Ndung'u, EK; Rossiter, PB; Stevenson, P | 1 |
Amsler-Delafosse, S; Bauer, B; Kaboré, I; Kamuanga, M | 1 |
Geerts, S; Goossens, B; Ndao, M; Osaer, S; Van Winghem, J | 1 |
Dávila, AM; Ortiz, AG; Pereira, SR; Ramirez, L; Silva, RA; Souza, SS | 1 |
Büscher, P; Faye, JA; Mattioli, RC | 1 |
Abebe, G; Afewerk, Y; Clausen, PH; Mehlitz, D; Tilahun, G | 1 |
Bradley, B; Eckersall, PD; Gow, JW; Kennedy, PG; McComb, C; Murray, M; Rodgers, J | 1 |
Abebe, G; Assefa, E | 1 |
Abdel Karim, EI; Mohamed-Ahmed, MM; Rahman, AH | 1 |
Ainanshe, OA; Holmes, PH; Jennings, FW | 1 |
Löhr, KF; Maloo, SH; Mbura, RJ; Münstermann, S | 1 |
Bruijn, JA; Fleuren, GJ; van Leer, EH; van Velthuysen, ML | 1 |
Claxton, JR; Dwinger, RH; Leperre, P; Rawlings, P; Snow, WF | 1 |
Adams, JH; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M | 1 |
Bauer, B; Clausen, PH; Kaboré, I; Sidibe, I | 1 |
Arakawa, A; Chitambo, H; Ono, T | 1 |
Aliu, YO; Gray, MA; Mamman, M; Moloo, SK; Peregrine, AS; Silayo, RS | 1 |
Munyua, WK; Njogu, AR; Olaho-Mukani, W | 1 |
Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M | 1 |
Jennings, FW | 2 |
Kaminsky, R; Zweygarth, E | 2 |
Egwu, GO; Onyeyili, PA; Orjiude, BA; Zaria, LT | 1 |
Onwualu, JE; Onyeyili, PA | 1 |
Arakawa, A; Chitambo, H | 1 |
Gettinby, G; McOdimba, FA; Moloo, SK; Murray, M; Paling, RW; Scott, JR | 1 |
Alushula, H; Dolan, RB; Mutugi, M; Njogu, AR; Okech, G; Sayer, PD; Stevenson, P | 1 |
Kaminsky, R; Webster, P; Zweygarth, E | 1 |
Ibitayo, AI; Knowles, G; Moloo, SK; Murphy, NB; Peregrine, AS; Scott, JR | 1 |
Hopkins, J; Luckins, AG; Mwangi, DM | 1 |
Anika, SM; Onyeyili, PA | 2 |
Chumo, DA; Kamar, KK; Muriithi, RM; Njogu, AR; Onyango, F; Reardon, MJ; Roberts, LM; Wellde, BT | 1 |
Chumo, DA; Higgs, J; Kovatch, RM; Preston, JM; Wellde, BT | 1 |
Ibe, CC; Wosu, LO | 1 |
Rogers, DJ | 1 |
Jefferies, D; Jenni, L | 2 |
Brown, HC; Holmes, PH; Jennings, FW; Waitumbi, JN | 1 |
Lekaki, KA; Mbwambo, HA; Mella, PN | 1 |
Alushula, H; Gatuta, GM; Mgutu, SP; Njogu, AR; Wilson, AJ | 1 |
Malu, MN; Tabel, H | 1 |
Gardiner, PR; Murray, M; Whitelaw, DD | 1 |
Gardiner, PR; Moloo, SK; Nelson, RT; Vos, GJ | 1 |
Otesile, EB; Tabel, H | 1 |
Gardiner, PR; Moloo, SK; Vos, GJ | 1 |
Kaggwa, E; Mugera, GM; Munyua, WK | 1 |
Röttcher, D; Zweygarth, E | 1 |
Moloo, SK; Röttcher, D; Schönefeld, A | 1 |
Jenni, L; Moloo, SK; Paling, RW | 1 |
Abebe, G | 1 |
Bafort, JM; Molyneux, DH; Schmidt, H | 1 |
Büttner, M; Reiter, I; Seitz, A | 1 |
Dwinger, RH; Luckins, AG; Moloo, SK; Murray, M; Rae, P | 1 |
Dehoux, JP; Demey, F; Makumyaviri, AM; Verhulst, A | 1 |
Black, SJ; Koch, GL; Sendashonga, CN; Shapiro, SZ; Webster, P | 1 |
Akpavie, SO; Egbunike, GN; Ikede, BO | 1 |
Akol, GW; Murray, M | 1 |
Moulton, JE | 1 |
Mitchell, LA; Pearson, TW | 1 |
Urquhart, GM; Whitelaw, DD | 1 |
Bovell, D; Brighouse, G; Poltera, AA; Rudin, W; Sayer, PD | 1 |
2 review(s) available for diminazene aceturate and Trypanosomiasis, African
Article | Year |
---|---|
Pharmacology of diminazene: a review.
Topics: Animals; Animals, Domestic; Diminazene; Drug Resistance; Drug Therapy, Combination; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 1993 |
Trypanosomiasis 'risk' or 'challenge': a review.
Topics: Africa, Eastern; Africa, Western; Animals; Cattle; Diminazene; Humans; Risk; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1985 |
8 trial(s) available for diminazene aceturate and Trypanosomiasis, African
Article | Year |
---|---|
Probiotic administration enhanced antitrypanosomal effects of diminazene aceturate in dogs experimentally infected with
Topics: Animals; Diminazene; Dogs; Female; Hemoglobins; Male; Parasitemia; Probiotics; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2022 |
Effects of Trypanosoma brucei infection and diminazene aceturate therapy on testicular morphology and function of Nigerian local dogs.
Topics: Animals; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Male; Nigeria; Parasitemia; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African | 2013 |
Collateral benefits of restricted insecticide application for control of African trypanosomiasis on Theileria parva in cattle: a randomized controlled trial.
Topics: Animals; Cattle; Diminazene; Endemic Diseases; Female; Insecticides; Male; Pyrethrins; Theileria parva; Theileriasis; Trypanocidal Agents; Trypanosomiasis, African | 2014 |
Effects of melarsamine hydrochloride (Cymelarsan) and diminazene aceturate (Berenil) on the pathology of experimental Trypanosoma brucei infection in red fronted gazelles (Gazella rufifrons).
Topics: Animals; Antelopes; Arsenicals; Diminazene; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Is trypanocidal drug resistance a threat for livestock health and production in endemic areas? Food for thoughts from Sahelian goats infected by Trypanosoma vivax in Bobo Dioulasso (Burkina Faso).
Topics: Animals; Burkina Faso; Diminazene; Drug Resistance; Female; Goat Diseases; Goats; Hematocrit; Parasitemia; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2012 |
Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense.
Topics: Animals; Antibodies, Protozoan; Diminazene; Drug Resistance; Flow Cytometry; Goat Diseases; Goats; Male; Phenotype; Trypanosoma congolense; Trypanosomiasis, African | 1995 |
Variation in sensitivity of Trypanosoma congolense to diminazene during the early phase of tsetse-transmitted infection in goats.
Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Diminazene; Drug Administration Schedule; Drug Resistance; Goat Diseases; Goats; Injections, Intramuscular; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1993 |
The influence of supplementation with cotton seed cake on the resistance of Ugandan goats to primary and secondary challenges with Trypanosoma congolense and on their response to treatment.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Diminazene; Food, Fortified; Goat Diseases; Goats; Hematocrit; Immunity, Innate; Male; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Uganda | 1997 |
161 other study(ies) available for diminazene aceturate and Trypanosomiasis, African
Article | Year |
---|---|
Trypanocidal 1,3-arylene diketone bis(guanylhydrazone)s. Structure-activity relationships among substituted and heterocyclic analogues.
Topics: Animals; Drug Evaluation, Preclinical; Female; Guanidines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Mitoguazone; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1984 |
DNA binding affinity of bisguanidine and bis(2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity.
Topics: Animals; DNA; Female; Guanidines; Imidazolines; Mice; Nucleoside Transport Proteins; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2006 |
Urea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis.
Topics: Benzothiazoles; Humans; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Urea | 2017 |
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Nitroimidazoles; Small Molecule Libraries; Structure-Activity Relationship; Trypanosomiasis, African | 2018 |
Novel distamycin analogues that block the cell cycle of African trypanosomes with high selectivity and potency.
Topics: Animals; Cell Cycle; Distamycins; Female; Macrophages; Mice; Mice, Inbred BALB C; Thiazoles; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 2020 |
Assessment of α-Cypermethrin Pour-On Application and Diminazene Aceturate for Treating Trypanosome-Related Diseases Caused by Tsetse Flies on Cattle in Mô, Togo.
Topics: Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Heteroptera; Pyrethrins; Togo; Trypanosoma; Trypanosomiasis, African; Tsetse Flies | 2022 |
African trypanosome infection patterns in cattle in a farm setting in Southern Ghana.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Farms; Female; Ghana; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2023 |
Variation of sensitivity of Trypanosoma evansi isolates from Isiolo and Marsabit counties of Kenya to locally available trypanocidal drugs.
Topics: Animals; Camelus; Chlorides; Diminazene; Drug Resistance; Kenya; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2023 |
Molecular identification of diminazene aceturate-resistant strains of Trypanosoma congolense in naturally infected domestic animals of Yoko in the centre region of Cameroon.
Topics: Animals; Cameroon; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance; Sheep; Sheep Diseases; Sheep, Domestic; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2020 |
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence | 2020 |
An ATP-Based Luciferase Viability Assay for Animal African Trypanosomes Using a 96-Well Plate.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Diminazene; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Luciferases; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African | 2017 |
Effects of Trypanosoma brucei brucei infection and diminazene aceturate administration on the blood pressure, heart rate, and temperature of Wistar albino rats.
Topics: Animals; Blood Pressure; Body Temperature; Diminazene; Heart Rate; Male; Rats; Rats, Wistar; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2018 |
Drug quality analysis of isometamidium chloride hydrochloride and diminazene diaceturate used for the treatment of African animal trypanosomosis in West Africa.
Topics: Africa, Western; Animals; Chromatography, High Pressure Liquid; Diminazene; Livestock; Phenanthridines; Quality Control; Trypanocidal Agents; Trypanosomiasis, African | 2018 |
How rational drug use reduces trypanosome infections in cattle in chemo-resistance hot-spot villages of northern Togo.
Topics: Albendazole; Animals; Antimicrobial Stewardship; Cattle; Diminazene; Drug Resistance; Insecticides; Male; Phenanthridines; Ticks; Togo; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2019 |
Diminazene aceturate (Berenil) downregulates Trypanosoma congolense-induced proinflammatory cytokine production by altering phosphorylation of MAPK and STAT proteins.
Topics: Animals; Cattle; Cell Line, Transformed; Cytokines; Diminazene; Female; Humans; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2019 |
Sustaining Efforts of Controlling Zoonotic Sleeping Sickness in Uganda Using Trypanocidal Treatment and Spray of Cattle with Deltamethrin.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Humans; Insect Vectors; Insecticides; Nitriles; Pyrethrins; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies; Uganda; Zoonoses | 2019 |
Suspected resistance of Trypanosoma species to diminazene aceturate on a cattle farm in Nigeria.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Intergenic; Drug Resistance; Farms; Nigeria; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2019 |
In vitro anti-trypanosomal effects of selected phenolic acids on Trypanosoma brucei.
Topics: Animals; Cell Proliferation; Cell Survival; Deferoxamine; Diminazene; Drug Resistance; Gallic Acid; Humans; Hydroxybenzoates; Iron; Mitochondrial Membranes; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 2019 |
Flavonoid mixture ameliorates increase in erythrocyte osmotic fragility and malondialdehyde concentration induced by Trypanosoma brucei brucei-infection in Wistar rats.
Topics: Animals; Diminazene; Diosmin; Erythrocytes; Male; Malondialdehyde; Osmotic Fragility; Parasitemia; Random Allocation; Rats; Rats, Wistar; Trypanosoma brucei brucei; Trypanosomiasis, African | 2014 |
Kenyan purple tea anthocyanins and coenzyme-Q10 ameliorate post treatment reactive encephalopathy associated with cerebral human African trypanosomiasis in murine model.
Topics: Animals; Anthocyanins; Body Weight; Central Nervous System Diseases; Diminazene; Female; Hematocrit; Humans; Mice; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Ubiquinone | 2014 |
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate.
Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
Evaluation of in vivo antitrypanosomal activity of crude extracts of Artemisia abyssinica against aTrypanosoma congolense isolate.
Topics: Animals; Artemisia; Diminazene; Female; Humans; Male; Mice; Parasitemia; Phytotherapy; Plant Components, Aerial; Plant Extracts; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
Effect of diminazene aceturate, levamisole and vitamin C combination therapy in rats experimentally infected with Trypanosoma brucei brucei.
Topics: Animals; Ascorbic Acid; Body Temperature; Body Weight; Diminazene; Drug Therapy, Combination; Hemoglobins; Leukocyte Count; Levamisole; Male; Parasite Load; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2014 |
Improvements on restricted insecticide application protocol for control of Human and Animal African Trypanosomiasis in eastern Uganda.
Topics: Albendazole; Animals; Cattle; Cattle Diseases; Diminazene; Female; Humans; Insect Control; Insecticides; Male; Population Density; Trypanosomiasis, African; Uganda | 2014 |
PCR and microsatellite analysis of diminazene aceturate resistance of bovine trypanosomes correlated to knowledge, attitude and practice of livestock keepers in South-Western Ethiopia.
Topics: Agriculture; Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Ethiopia; Health Knowledge, Attitudes, Practice; Livestock; Longitudinal Studies; Microsatellite Repeats; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2015 |
In vivo experimental drug resistance study in Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Communicable Diseases; Diminazene; Drug Resistance; Ethiopia; Insect Vectors; Male; Parasitemia; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Tsetse Flies | 2015 |
Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments.
Topics: Animals; B-Lymphocyte Subsets; Bone Marrow; Diminazene; Female; Lymphopoiesis; Mice; Mice, Inbred C57BL; Spleen; Suramin; Trypanocidal Agents; Trypanosomiasis; Trypanosomiasis, African | 2015 |
Novel trypanocide from an extract of Pleurotus sajor-caju against Trypanosoma congolense.
Topics: Animals; Biomarkers; Body Weight; Diminazene; Disease Models, Animal; Dose-Response Relationship, Drug; Mice, Inbred BALB C; Parasitemia; Pleurotus; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2017 |
IgM, lgG and IL-6 profiles in the Trypanosoma brucei brucei monkey model of human African trypanosomiasis.
Topics: Animals; Antigens, Protozoan; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Immunoglobulin G; Immunoglobulin M; Interleukin-6; Trypanosoma brucei brucei; Trypanosomiasis, African | 2017 |
Trypanosomiasis challenge estimation using the diminazene aceturate (Berenil) index in Zebu in Gabon.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Gabon; Longitudinal Studies; Rain; Seasons; Tropical Climate; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2017 |
Cattle breeding, trypanosomosis prevalence and drug resistance in Northern Togo.
Topics: Animals; Breeding; Cattle; Cattle Diseases; Communicable Disease Control; Cross-Sectional Studies; Diminazene; Drug Resistance; Phenanthridines; Prevalence; Togo; Treatment Failure; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2017 |
Five-fold increase in Trypanosoma congolense isolates resistant to diminazene aceturate over a seven-year period in Eastern Zambia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Protozoan; Dose-Response Relationship, Drug; Drug Resistance; Mice; Mice, Inbred Strains; Polymorphism, Restriction Fragment Length; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zambia | 2008 |
Immunospecific immunoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys.
Topics: Animals; Antigens, Protozoan; Biomarkers; Brain; Chlorocebus aethiops; Diminazene; Female; Immunoglobulin G; Immunoglobulin M; Interleukin-10; Male; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2009 |
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense.
Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2011 |
Genital lesions in male red fronted gazelles (Gazella rufifrons) experimentally infected with Trypanosoma brucei and the effect of melarsamine hydrochloride (Cymelarsan®) and diminazene aceturate (Berenil®) in its treatment.
Topics: Animals; Antelopes; Arsenicals; Body Temperature; Diminazene; Genital Diseases, Male; Hematocrit; Histocytochemistry; Male; Parasitemia; Semen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2011 |
Highly debilitating natural Trypanosoma vivax infections in Brazilian calves: epidemiology, pathology, and probable transplacental transmission.
Topics: Animals; Antiprotozoal Agents; Brazil; Cattle; Cattle Diseases; Diminazene; Infectious Disease Transmission, Vertical; Parasitemia; Prevalence; Severity of Illness Index; Survival Analysis; Trypanosoma vivax; Trypanosomiasis, African | 2012 |
The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats.
Topics: Animals; Azadirachta; Diminazene; Drug Resistance; Drug Therapy, Combination; Female; Male; Parasitemia; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Trypanosoma brucei brucei; Trypanosomiasis, African | 2011 |
High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.
Topics: Africa South of the Sahara; Alleles; Animals; Antiprotozoal Agents; Diminazene; Disease Models, Animal; DNA, Protozoan; Drug Resistance; Mice; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Selection, Genetic; Trypanosoma congolense; Trypanosomiasis, African | 2011 |
Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Cross-Sectional Studies; Diminazene; Longitudinal Studies; Phenanthridines; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2012 |
Investigation of the antitrypanosomal activity of Buchholzia coriacea seed extract against a field strain of Trypanosoma congolense.
Topics: Administration, Oral; Animals; Capparaceae; Diminazene; Dose-Response Relationship, Drug; Female; Hematocrit; Male; Methanol; Mice; Parasitemia; Phytotherapy; Plant Extracts; Seeds; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2011 |
Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali.
Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Mali; Phenanthridines; Rural Population; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 2012 |
Biochemical and morphological changes in Trypanosoma brucei brucei-infected rats treated with homidium chloride and diminazene aceturate.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Diminazene; Ethidium; Male; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2012 |
Diminazene aceturate (Berenil) modulates the host cellular and inflammatory responses to Trypanosoma congolense infection.
Topics: Animals; Cytokines; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Forkhead Transcription Factors; Immunity, Cellular; Inflammation; Interleukin-2 Receptor alpha Subunit; Kupffer Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Spleen; T-Lymphocytes; Trypanosoma congolense; Trypanosomiasis, African | 2012 |
Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda.
Topics: Animals; Cattle; Diminazene; Disease Models, Animal; Drug Resistance; Ethidium; Female; Goat Diseases; Goats; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda | 2002 |
Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate.
Topics: Blood-Brain Barrier; Diminazene; Drug Carriers; Drug Compounding; Drug Stability; Humans; Lipids; Microspheres; Nanotechnology; Particle Size; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Trypanocidal Agents; Trypanosomiasis, African | 2002 |
[Trypanosomiasis and babesiasis in Africa and their treatment with the new preparation berenil].
Topics: Africa; Amidines; Aniline Compounds; Animals; Apicomplexa; Babesiosis; Cattle; Cattle Diseases; Coloring Agents; Diminazene; Dog Diseases; Dogs; Infections; Trypanosomiasis; Trypanosomiasis, African | 1955 |
A strain of Trypanosoma congolense directly resistant to berenil.
Topics: Animals; Antiparasitic Agents; Azo Compounds; Diminazene; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African | 1963 |
DRUG-RESISTANCE OF TRYPANOSOMA CONGOLENSE AND OTHER TRYPANOSOMES TO QUINAPYRAMINE, PHENANTHRIDINES, BERENIL AND OTHER COMPOUNDS IN MICE.
Topics: Animals; Antiprotozoal Agents; Diminazene; Mice; Phenanthridines; Quinolines; Quinolinium Compounds; Research; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African | 1963 |
Berenil in the treatment of Trypanosoma gambiense infection in man.
Topics: Amidines; Aniline Compounds; Animals; Black People; Diminazene; Humans; Trypanosoma brucei gambiense; Trypanosomiasis; Trypanosomiasis, African | 1962 |
A large-scale trial to evaluate the efficacy of a 1% pour-on formulation of cyfluthrin (Cylence, Bayer) in controlling bovine trypanosomosis in Eastern Zambia.
Topics: Administration, Topical; Animals; Cattle; Diminazene; Hematocrit; Incidence; Insecticides; Nitriles; Pyrethrins; Seasons; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Zambia | 2004 |
The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.
Topics: Adenosine; Animals; Biological Transport, Active; Diminazene; Drug Resistance; Female; Kinetics; Mutation; Nucleoside Transport Proteins; Rats; Rats, Wistar; Saccharomyces cerevisiae; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2004 |
Trypanocidal failure suggested by PCR results in cattle field samples.
Topics: Animals; Cattle; Diminazene; Drug Resistance, Microbial; Parasitic Sensitivity Tests; Phenanthridines; Polymerase Chain Reaction; Sensitivity and Specificity; Treatment Failure; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2004 |
Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda.
Topics: Animals; Cattle; Diminazene; Female; Insect Control; Male; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Uganda | 2004 |
Transition models to assess risk factors for new and persistent trypanosome infections in cattle-analysis of longitudinal data from the Ghibe Valley, southwest Ethiopia.
Topics: Age Factors; Animals; Cattle; Diminazene; Ethiopia; Female; Incidence; Insect Control; Insect Vectors; Longitudinal Studies; Male; Models, Biological; Odds Ratio; Prevalence; Recurrence; Risk Factors; Seasons; Sensitivity and Specificity; Sex Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 2004 |
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.
Topics: Animals; Diminazene; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Female; Parasitic Sensitivity Tests; Pentamidine; Random Allocation; Rats; Recurrence; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2006 |
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.
Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2006 |
Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection.
Topics: Animals; Diminazene; Disease Susceptibility; Goat Diseases; Goats; Male; Nigeria; Parasitemia; Random Allocation; Treatment Outcome; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2006 |
The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride.
Topics: Animals; Diminazene; Drug Resistance; Ethidium; Mice; Mozambique; Parasitic Sensitivity Tests; Phenanthridines; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2005 |
Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system.
Topics: Abortion, Veterinary; Animals; Antibodies, Protozoan; Brain; Brazil; Cattle; Cattle Diseases; Diminazene; Disease Outbreaks; Female; Nervous System; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2007 |
Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients.
Topics: Animals; Diminazene; Drug Resistance, Multiple; Humans; Kenya; Melarsoprol; Mice; Parasitic Sensitivity Tests; Phenanthridines; Random Allocation; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda | 2007 |
Acute phase response in mice experimentally infected with Trypanosoma congolense: a molecular gauge of parasite-host interaction.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Anemia; Animals; Diminazene; Disease Models, Animal; Female; Haptoglobins; Hematocrit; Host-Parasite Interactions; Mice; Random Allocation; Serum Amyloid P-Component; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2008 |
Relapse of monomorphic and pleomorphic Trypanosoma brucei infections in the mouse after chemotherapy.
Topics: Amidines; Animals; Brain; Diminazene; Female; Mice; Recurrence; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Chemotherapy of Trypanosoma brucei in mice with diminazene aceturate. Variation in the aparasitaemic period over 5 years.
Topics: Amidines; Animals; Blood; Diminazene; Freezing; Mice; Preservation, Biological; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Lymphocyte function in experimental African trypanosomiasis. VII. Loss of antigen-nonspecific suppressor-T-cell activity.
Topics: Animals; Antibody Formation; Antigens, Ly; Diminazene; Immune Tolerance; Male; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes, Regulatory; Trypanosoma; Trypanosomiasis, African | 1984 |
Retrospective long-term study of effects of berenil by follow-up of patients treated since 1965.
Topics: Adolescent; Adult; Amidines; Cerebrospinal Fluid; Child; Child, Preschool; Diminazene; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Trypanocidal Agents; Trypanosomiasis, African; Uganda; Urine | 1984 |
Persistence of Berenil in cattle.
Topics: Amidines; Animals; Cattle; Diminazene; Kenya; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1983 |
Observation on drug resistance of Trypanosoma (Nannomonas) congolense and Trypanosoma (Duttonella) vivax in cattle at a feedlot in the Northern Ivory Coast.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Male; Phenanthridines; Quaternary Ammonium Compounds; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1983 |
The use of the 2 substituted 5-nitroimidazole, Fexinidazole (Hoe 239) in the treatment of chronic T. brucei infections in mice.
Topics: Animals; Antiprotozoal Agents; Chronic Disease; Diminazene; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Studies in rabbits on the disposition and trypanocidal activity of the anti-trypanosomal drug, diminazene aceturate (Berenil).
Topics: Amidines; Animals; Diminazene; Kinetics; Rabbits; Tissue Distribution; Trypanosomiasis, African | 1983 |
Maintaining zebu Maure cattle in a tsetse infested area of Mali.
Topics: Animals; Body Weight; Cattle; Diminazene; Female; Male; Mali; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1984 |
Response of the rat's hepatic drug-metabolizing enzyme system to chemotherapy of Trypanosoma b. brucei infections with Berenil and Suramin.
Topics: Amidines; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Diminazene; Female; Glutamate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Liver; Microsomes, Liver; Phospholipids; Rats; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1984 |
Relapsed parasitaemia following chemotherapy of chronic T. brucei infections in mice and its relation to cerebral trypanosomes.
Topics: Animals; Antiprotozoal Agents; Brain; Chronic Disease; Diminazene; Mice; Recurrence; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Studies of choroid plexus involvement in chronic infections of mice with Trypanosoma brucei gambiense.
Topics: Animals; Antiprotozoal Agents; Choroid Plexus; Chronic Disease; Diminazene; Mice; Nifurtimox; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Delay in resolution of trypanosome-induced genital lesions in male rabbits infected with Trypanosoma brucei and treated with diminazene aceturate.
Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Genital Diseases, Male; Genitalia, Male; Male; Rabbits; Scrotum; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Pharmacokinetics and efficacy of the trypanocide diminazene aceturate (Berenil) in rabbits.
Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Kinetics; Rabbits; Trypanosomiasis, African | 1982 |
Diminazene aceturate in the treatment of experimentally induced Trypanosoma brucei brucei infection in domestic chickens.
Topics: Amidines; Animals; Antiprotozoal Agents; Chickens; Diminazene; Humans; Mice; Poultry Diseases; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
The efficacy of berenil (diminazene aceturate) against Trypanosoma evansi infection in mice.
Topics: Amidines; Animals; Antiprotozoal Agents; Blood; Diminazene; Female; Male; Mice; Mice, Inbred Strains; Species Specificity; Trypanosoma; Trypanosomiasis, African | 1982 |
'Berenil' and nitroimidazole combinations in the treatment of Trypanosoma brucei infection with central nervous system involvement.
Topics: Amidines; Animals; Benzamidines; Central Nervous System Diseases; Diminazene; Ethidium; Female; Isoxazoles; Mice; Nitroimidazoles; Phenanthridines; Ronidazole; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1980 |
The quantitation of trypanosoma congolense in calves. III. A quantitative comparison of trypanosomes in jugular vein and microvasculature and tests of dispersing agents.
Topics: Animals; Animals, Newborn; Brain; Capillaries; Cattle; Dexamethasone; Diminazene; Jugular Veins; Liver; Male; Muscles; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1980 |
Disposition of diminazene aceturate (Berenil) in trypanosome-infected pregnant and lactating cows.
Topics: Animals; Animals, Suckling; Cattle; Diminazene; Female; Lactation; Milk; Pregnancy; Pregnancy Complications, Parasitic; Tissue Distribution; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1995 |
Use of monoclonal antibodies for detecting T brucei brucei infection in splenectomised dogs.
Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Male; Splenectomy; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1995 |
Variations in packed red cell volume and trypanosome prevalence and relationships with reproductive traits in east African Zebu cows exposed to drug-resistant trypanosomes.
Topics: Abortion, Veterinary; Animals; Cattle; Diminazene; Drug Resistance; Ethiopia; Female; Hematocrit; Incidence; Lactation; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Reproduction; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1995 |
Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivo.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Diminazene; DNA Damage; Female; Immune Tolerance; Immunotherapy, Adoptive; Lymphocyte Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Nitric Oxide; Spleen; T-Lymphocytes; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
Drug sensitivity screening in vitro of populations of Trypanosoma congolense originating from cattle and tsetse flies at Nguruman, Kenya.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1993 |
Trypanosoma brucei, T. congolense and T. vivax infections in horses on a farm in Kenya.
Topics: Animals; Diminazene; Disease Outbreaks; Horse Diseases; Horses; Kenya; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African | 1994 |
Relapse of Trypanosoma congolense infection in goats after diminazene aceturate is not a result of invasion of the central nervous system.
Topics: Animals; Diminazene; Goat Diseases; Goats; Male; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1994 |
Combination chemotherapy of drug-resistant Trypanosoma brucei rhodesiense infections in mice using DL-alpha-difluoromethylornithine and standard trypanocides.
Topics: Animals; Arsenicals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Eflornithine; Female; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1994 |
The effect of trypanocidal drug treatment on the haematological changes in Trypanosoma brucei brucei infected splenectomised dogs.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Diminazene; Dog Diseases; Dogs; Erythrocyte Count; Erythrocyte Indices; Female; Hematocrit; Hemoglobins; Leukocyte Count; Male; Reticulocytes; Splenectomy; Trypanosoma brucei brucei; Trypanosomiasis, African | 1993 |
The chemotherapeutic efficacy of diminazene aceturate and lithium chloride against relapse infection of Trypanosoma brucei brucei in rats.
Topics: Animals; Blood-Brain Barrier; Dexamethasone; Diminazene; Drug Therapy, Combination; Female; Lithium Chloride; Male; Parasitemia; Rats; Rats, Wistar; Recurrence; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
The effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations.
Topics: Acute-Phase Reaction; Animals; Diminazene; Hematocrit; Iron; Leukocyte Count; Male; Rabbits; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Zinc | 1995 |
Kinetoplasts play an important role in the drug responses of Trypanosoma brucei.
Topics: Acriflavine; Animals; Azides; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Ethidium; Female; Light; Mice; Mitochondria; Mitoguazone; Mutation; Parasitemia; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
The effects of hyperosmolar agents lithium chloride and sucrose on the brain concentration of diminazene aceturate in rats.
Topics: Animals; Blood-Brain Barrier; Brain; Diminazene; Female; Lithium Chloride; Male; Permeability; Rats; Rats, Wistar; Sucrose; Tissue Distribution; Trypanocidal Agents; Trypanosomiasis, African | 1995 |
Resistance to diminazine aceturate by Trypanosoma congolense from cattle in the Zambezi Valley of Zimbabwe.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zimbabwe | 1995 |
Effect of tsetse control on trypanosome prevalence in livestock: problems of experimental design and statistical interpretation--a case study in northern Côte d'Ivoire.
Topics: Animal Husbandry; Animals; Cattle; Cote d'Ivoire; Diminazene; Insect Control; Insect Vectors; Sheep; Sheep Diseases; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1996 |
Effect of diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense in Glossina morsitans centralis.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Goats; Insect Vectors; Male; Mice; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1997 |
The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis.
Topics: Animals; Brain; Brain Diseases; Diminazene; Eflornithine; Female; Mice; Mice, Inbred Strains; Polyamines; Putrescine; Trypanocidal Agents; Trypanosomiasis, African | 1997 |
Response of a T. b. rhodesiense stock with reduced drug susceptibility in vitro to treatment in mice and cattle.
Topics: Animals; Cattle; Diminazene; DNA, Protozoan; Drug Resistance; Male; Mice; Phenanthridines; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda | 1998 |
Immunoregulation in experimental murine Trypanosoma congolense infection: anti-IL-10 antibodies reverse trypanosome-mediated suppression of lymphocyte proliferation in vitro and moderately prolong the lifespan of genetically susceptible BALB/c mice.
Topics: Animals; Diminazene; Disease Susceptibility; Female; Interleukin-10; Life Expectancy; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; T-Lymphocytes; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1998 |
Cytokines and antibody responses during Trypanosoma congolense infections in two inbred mouse strains that differ in resistance.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cytokines; Diminazene; Epitopes, B-Lymphocyte; Female; Immunity, Innate; Interferon-gamma; Interleukin-10; Interleukin-4; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; Spleen; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma | 1999 |
Rinderpest vaccination and the incidence and development of trypanosomosis in cattle.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Hematocrit; Incidence; Insect Vectors; Kenya; Male; Neutralization Tests; Rinderpest; Rinderpest virus; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Vaccination; Viral Vaccines | 1999 |
Improvement of cattle productivity through rapid alleviation of African animal trypanosomosis by integrated disease management practices in the agropastoral zone of Yalé, Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Diminazene; Female; Hematocrit; Humans; Insect Control; Insect Vectors; Insecticides; Interviews as Topic; Milk; Nitriles; Pregnancy; Pyrethrins; Seasons; Sentinel Surveillance; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1999 |
The susceptibility of Djallonké and Djallonké-Sahelian crossbred sheep to Trypanosoma congolense and helminth infection under different diet levels.
Topics: Animal Feed; Animals; Anthelmintics; Antibodies, Protozoan; Antiprotozoal Agents; Crosses, Genetic; Diminazene; Disease Susceptibility; Feces; Female; Fenbendazole; Gambia; Helminthiasis, Animal; Helminths; Hematocrit; Male; Nutritional Status; Parasite Egg Count; Parasitemia; Random Allocation; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African | 1999 |
Hematology of natural bovine trypanosomosis in the Brazilian Pantanal and Bolivian wetlands.
Topics: Abortion, Veterinary; Anemia, Hypochromic; Anemia, Macrocytic; Animals; Bolivia; Brazil; Cattle; Diarrhea; Diminazene; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Leukocyte Count; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1999 |
Susceptibility of N'Dama cattle to experimental challenge and cross-species superchallenges with bloodstream forms of Trypanosoma congolense and T. vivax.
Topics: Animals; Cattle; Diminazene; Disease Susceptibility; Gambia; Hematocrit; Male; Parasitemia; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Weight Gain | 1999 |
Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Ethiopia; Mice; Mice, Inbred BALB C; Parasitemia; Phenanthridines; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2000 |
Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Cytokines; Diminazene; Disease Models, Animal; Encephalitis; Female; Haptoglobins; Mice; Parasitemia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Amyloid P-Component; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2001 |
Drug-resistant Trypanosoma congolense in naturally infected donkeys in north Omo Zone, southern Ethiopia.
Topics: Animals; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Equidae; Ethiopia; Female; Male; Mice; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2001 |
Multiple drug-resistant bovine trypanosomes in South Darfur Province, Sudan.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Phenanthridines; Sudan; Time Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Isolation of drug-resistant strains of Trypanosoma congolense from the lower Shabelle region of southern Somalia.
Topics: Animals; Animals, Domestic; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Recurrence; Somalia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Trypanosomiasis control in Boran cattle in Kenya: a comparison between chemoprophylaxis and a parasite detection and intravenous treatment method using isometamidium chloride.
Topics: Animals; Cattle; Diminazene; Drug Administration Schedule; Female; Injections, Intramuscular; Injections, Intravenous; Kenya; Male; Phenanthridines; Risk Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Pathogenesis of trypanosomiasis-induced glomerulonephritis in mice.
Topics: Animals; Antibodies; Basement Membrane; Diminazene; Female; Glomerulonephritis; Kidney Glomerulus; Mice; Mice, Inbred BALB C; Trypanosomiasis, African | 1992 |
Trypanosomiasis in cattle in Gambia: incidence, prevalence and tsetse challenge.
Topics: Animals; Breeding; Cattle; Diminazene; Female; Gambia; Incidence; Insect Vectors; Male; Prevalence; Regression Analysis; Seasons; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1992 |
Subcurative chemotherapy and fatal post-treatment reactive encephalopathies in African trypanosomiasis.
Topics: Adolescent; Adult; Animals; Arsenicals; Brain; Brain Diseases; Child; Child, Preschool; Diminazene; Female; Humans; Male; Mice; Nitroimidazoles; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
Development of multiple drug resistance of Trypanosoma congolense in Zebu cattle under high natural tsetse fly challenge in the pastoral zone of Samorogouan, Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Diminazene; Drug Resistance; Prevalence; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1992 |
In vivo assessment of drug sensitivity of African trypanosomes using the akinetoplastic induction test.
Topics: Animals; Cattle; Diminazene; Mice; Phenanthridines; Rosaniline Dyes; Staining and Labeling; Toluidines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Response of Trypanosoma congolense in goats to single and double treatment with diminazene aceturate.
Topics: Animals; Chromatography, High Pressure Liquid; Diminazene; Drug Administration Schedule; Goat Diseases; Goats; Hematocrit; Lymph Nodes; Male; Skinfold Thickness; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1992 |
An enzyme-linked immunosorbent assay (ELISA) for the detection of trypanosomal antigens in goat serum using a monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Diminazene; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Goats; Immunoglobulin M; Sensitivity and Specificity; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis.
Topics: Animals; Azathioprine; Brain Diseases; Diminazene; Disease Models, Animal; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosomiasis, African | 1992 |
Chemotherapy of CNS-trypanosomiasis: the combined use of diminazene aceturate or pentamidine with DL-alpha-difluoromethylornithine (DFMO).
Topics: Animals; Arsenicals; Central Nervous System Diseases; Diminazene; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Mice; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
Evaluation of DL-alpha-difluoromethylornithine against susceptible and drug-resistant Trypanosoma brucei brucei.
Topics: Animals; Arsenicals; Culture Media; Diminazene; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Humans; Immune Sera; Male; Mice; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
The effect of verapamil alone and in combination with trypanocides on multidrug-resistant Trypanosoma brucei brucei.
Topics: Animals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Female; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Verapamil | 1991 |
DL-alpha-difluoromethylornithine (DFMO)-Berenil combination: therapeutic and prophylactic activity against Trypanosoma brucei brucei infection in mice.
Topics: Animals; Diminazene; Drug Therapy, Combination; Eflornithine; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Efficacy of combination of DFMO and diminazene aceturate in the treatment of late stage Trypanosoma brucei brucei infection in rats.
Topics: Animals; Brain Diseases; Diminazene; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Male; Rats; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Zambia | 1991 |
Susceptibility of N'Dama and Boran cattle to sequential challenges with tsetse-transmitted clones of Trypanosoma congolense.
Topics: Anemia; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Body Weight; Cattle; Diminazene; Disease Susceptibility; Female; Hematocrit; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1991 |
Homidium bromide as a chemoprophylactic for cattle trypanosomiasis in Kenya.
Topics: Animals; Cattle; Diminazene; Ethidium; Hematocrit; Kenya; Male; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Weight Gain | 1990 |
Trypanosoma brucei evansi: dyskinetoplasia and loss of infectivity after long-term in vitro cultivation.
Topics: Animals; Diminazene; DNA, Circular; DNA, Kinetoplast; Female; Male; Mice; Microscopy, Electron; Phenanthridines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1990 |
Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Genetic Variation; Isoenzymes; Mice; Phenanthridines; Phenotype; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1991 |
Cellular phenotypes in Trypanosoma congolense infected sheep: the local skin reaction.
Topics: Animals; Antibodies, Monoclonal; Diminazene; Immunophenotyping; Lymphocyte Subsets; Sheep; Sheep Diseases; Skin; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1990 |
Effects of the combination of DL-alpha-difluoromethylornithine and diminazene aceturate in Trypanosoma congolense infection of dogs.
Topics: Animals; Diminazene; Dog Diseases; Dogs; Drug Therapy, Combination; Eflornithine; Female; Male; Trypanosoma congolense; Trypanosomiasis, African | 1990 |
Natural and acquired resistance to Trypanosoma vivax in cattle.
Topics: Animals; Cattle; Diminazene; Gastrointestinal Hemorrhage; Goats; Immunity, Active; Immunity, Innate; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1989 |
Trypanosoma congolense: erythrocyte indices, plasma iron turnover and effects of treatment in infected cattle.
Topics: Anemia, Hemolytic; Animals; Cattle; Cattle Diseases; Diminazene; Erythrocyte Count; Erythrocyte Indices; Hematocrit; Iron; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1989 |
Use of extracts of Picralima nitida bark in the treatment of experimental trypanosomiasis: a preliminary study.
Topics: Animals; Diminazene; Drug Evaluation, Preclinical; Female; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1989 |
The influence of Trypanosoma congolense infection on the disposition kinetics of diminazene aceturate in the dog.
Topics: Amidines; Animals; Diminazene; Dog Diseases; Dogs; Injections, Intravenous; Male; Regression Analysis; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1989 |
The effect of trypanocidal drugs on the transmission of Trypanosoma brucei brucei by Glossina morsitans centralis.
Topics: Animals; Diminazene; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tsetse Flies | 1987 |
The effect of the trypanocidal drugs berenil and samorin on infections of Glossina morsitans centralis by Trypanosoma congolense.
Topics: Amidines; Animals; Diminazene; Insect Vectors; Male; Mice; Mice, Inbred ICR; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1987 |
The relapse of Trypanosoma brucei brucei infections after chemotherapy in rabbits.
Topics: Amidines; Animals; Diminazene; Female; Male; Mice; Rabbits; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
Berenil (diminazene aceturate)-resistant Trypanosoma congolense in cattle under natural tsetse challenge at Kibaha, Tanzania.
Topics: Amidines; Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Tanzania; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1988 |
A simple epidemiological method for animal trypanosomiasis to provide relevant data for effective financial decision-making.
Topics: Age Factors; Animals; Body Weight; Cattle; Cost-Benefit Analysis; Diminazene; Female; Kenya; Male; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1986 |
The alternative pathway of complement in sheep during the course of infection with Trypanosoma congolense and after Berenil treatment.
Topics: Animals; Antibodies, Bacterial; Brucella abortus; Complement Activation; Complement C3; Complement Factor B; Complement Pathway, Alternative; Diminazene; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African | 1986 |
Extravascular foci of Trypanosoma vivax in goats: the central nervous system and aqueous humor of the eye as potential sources of relapse infections after chemotherapy.
Topics: Animals; Aqueous Humor; Central Nervous System Diseases; Cerebrospinal Fluid; Choroid Plexus; Diminazene; Goats; Male; Mice; Recurrence; Trypanosoma; Trypanosomiasis, African | 1988 |
Attempts to protect goats against challenge with Trypanosoma vivax by initiation of primary infections with large numbers of metacyclic trypanosomes.
Topics: Animals; Antibodies, Protozoan; Diminazene; Goats; Male; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies | 1988 |
Enhanced resistance of highly susceptible Balb/c mice to infection with Trypanosoma congolense after infection and cure.
Topics: Agglutination Tests; Animals; Antibodies, Protozoan; Antigenic Variation; Diminazene; Female; Fluorescent Antibody Technique; Immune Sera; Immunity, Active; Immunization, Passive; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rabbits; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1987 |
Susceptibility of goats to tsetse-transmitted challenge with Trypanosoma vivax from East and West Africa.
Topics: Africa, Eastern; Africa, Western; Animals; Chronic Disease; Diminazene; Disease Susceptibility; Goats; Immunity, Active; Insect Vectors; Male; Recurrence; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies; Virulence | 1988 |
Relapses in dogs experimentally infected with Trypanosoma brucei and treated with diminazene aceturate or isometamidium chloride.
Topics: Alanine Transaminase; Amidines; Animals; Antibodies, Protozoan; Aspartate Aminotransferases; Diminazene; Dog Diseases; Dogs; Fever; Hematocrit; Hemoglobins; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
The treatment of Trypanosoma (Nannomonas) simiae in pigs with diminazene aceturate in combination with a 5-substituted 2-nitroimidazole compound (Ro 15-0216).
Topics: Acetanilides; Amidines; Animals; Diminazene; Drug Therapy, Combination; Female; Male; Mice; Nitroimidazoles; Swine; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 1987 |
The sensitivity to trypanocidal drugs of Trypanosoma vivax isolated in Kenya and Somalia.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Male; Phenanthridines; Quinolinium Compounds; Somalia; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Trypanosoma congolense: host responses following tsetse transmitted infection of Kilifi isolates in goats.
Topics: Animals; Antibody Formation; Antigens, Protozoan; Cattle; Diminazene; Glucose-6-Phosphate Isomerase; Goats; Isoenzymes; Kenya; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1987 |
Failure of berenil therapy to eliminate early infections with a strain of Trypanosoma brucei from West Abaya, Ethiopia.
Topics: Amidines; Animals; Cattle; Diminazene; Ethiopia; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Effect of tetracycline administration on the efficacy of diminazene aceturate therapy and prophylaxis in Trypanosoma brucei infections of mice.
Topics: Amidines; Animals; Diminazene; Drug Therapy, Combination; Mice; Oxytetracycline; Rolitetracycline; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Development of Trypanosoma brucei in suckling mouse brain following intracerebral injection.
Topics: Animals; Animals, Suckling; Brain; Diminazene; Injections, Intraventricular; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Trypanosoma theileri Laveran, 1902, in naturally and experimentally infected cattle: parasite isolation, serological and cellular reactions and Berenil sensitivity.
Topics: Amidines; Animals; Antibodies, Protozoan; Cattle; Diminazene; Immunity, Cellular; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse.
Topics: Animals; Antibody Formation; Diminazene; Goats; Male; Neutralization Tests; Skin; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1986 |
[Duration of the preventive action of diminazene aceturate on experimental infection of NMRI mice with metacyclic forms of Trypanosoma brucei brucei].
Topics: Amidines; Animals; Diminazene; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Regulation of parasite-specific antibody responses in resistant (C57BL/6) and susceptible (C3H/HE) mice infected with Trypanosoma (trypanozoon) brucei brucei.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Diminazene; Disease Susceptibility; Female; Immune Tolerance; Immunity, Innate; Immunoglobulins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Electron; Spleen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Ejaculate characteristics of sheep infected with Trypanosoma brucei and T vivax: changes caused by treatment with diminazene aceturate.
Topics: Animals; Diminazene; Male; Semen; Sheep; Sheep Diseases; Sperm Count; Sperm Motility; Spermatozoa; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Induction of protective immunity in cattle by tsetse-transmitted cloned isolates of Trypanosoma congolense.
Topics: Animals; Antibody Formation; Cattle; Diminazene; Female; Hypersensitivity; Male; Mice; Mice, Inbred A; Neutralization Tests; Skin; Skin Tests; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1985 |
Relapse infection after chemotherapy in goats experimentally infected with Trypanosoma brucei: pathological changes in central nervous system.
Topics: Amidines; Animals; Blood-Brain Barrier; Central Nervous System; Choroiditis; Diminazene; Goats; Male; Meningitis; Orchiectomy; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Antibody responses in resistant and susceptible inbred mice infected with Trypanosoma congolense.
Topics: Animals; Antibody Specificity; Antigens, Protozoan; Antigens, Surface; Diminazene; Disease Susceptibility; Female; Glycoproteins; Immunity, Innate; Immunoglobulin G; Immunoglobulin M; Male; Membrane Proteins; Mice; Mice, Inbred A; Mice, Inbred C57BL; Rats; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma | 1986 |
Maternally derived immunity in young mice to infection with Trypanosoma brucei and its potentiation by Berenil chemotherapy.
Topics: Age Factors; Amidines; Animals; Animals, Suckling; Colostrum; Diminazene; Female; Immunization, Passive; Mice; Pregnancy; Trypanosoma brucei brucei; Trypanosomiasis, African | 1985 |
Immunopathological aspects of trypanosomal meningoencephalitis in vervet monkeys after relapse following Berenil treatment.
Topics: Amidines; Animals; Antigen-Antibody Complex; Autoantibodies; Blood-Brain Barrier; Brain; Chlorocebus aethiops; Diminazene; Immunoglobulin G; Immunoglobulin M; Meningoencephalitis; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1985 |