diminazene aceturate has been researched along with Disease Models, Animal in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.06) | 18.7374 |
| 1990's | 3 (9.09) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 17 (51.52) | 24.3611 |
| 2020's | 6 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Bacchi, CJ; Braillard, S; Chatelain, E; Denny, WA; Gaukel, E; Launay, D; Maes, L; Marshall, AJ; Mowbray, CE; Thompson, AM; Wring, SA; Yarlett, N | 1 |
| Evans, CE; Good, MA; Heard, DM; Kehoe, PG; Kidd, EJ; Miners, JS; Piva, G; Willis, CL | 1 |
| Fujita, M; Hung, WY; Nakagawa, K; Nakagawasai, O; Nemoto, W; Tadano, T; Tan-No, K; Yamagata, R | 1 |
| Atanasova, KR; Bravo, L; Collins, EN; Dadural, JS; Eken, E; Guevara, MV; Kuan, SP; Liao, YSJ; Reznikov, LR; Schurmann, V; Sponchiado, M; Vogt, K | 1 |
| Chai, CY; Chen, IC; Dai, ZK; Hsu, JH; Lin, JY; Liu, YC; Wu, BN; Yeh, JL | 1 |
| Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK | 1 |
| Białas, M; Bujak-Giżycka, B; Jawień, J; Kiepura, A; Kuś, K; Olszanecki, R; Stachowicz, A; Stachyra, K; Suski, M; Totoń-Żurańska, J; Wiśniewska, A; Łomnicka, M | 1 |
| Bruce, EB; Cahill, KM; de Kloet, AD; Hiller, H; Katovich, MJ; Krause, EG; Ludin, JA; Pioquinto, DJ; Raizada, MK; Smeltzer, MD; Wang, LA | 1 |
| Bruce, EB; Carter, CS; Kirichenko, N; Morgan, D; Sakarya, Y; Scarpace, PJ; Sumners, C; Toklu, HZ; Tümer, N | 1 |
| Birhanu, H; Büscher, P; Kidane, W; Mekonnen, G; Mohammed, EF; Nesibu, A; Van Reet, N; Yohannes, H | 1 |
| El-Sayed, SAE; Igarashi, I; Rizk, MA; Yokoyama, N | 1 |
| Cardoso, VN; Faraco, AA; Fernandes, RS; Fernandes, SO; Ferreira, AJ; Foureaux, G; Franca, JR; Fulgêncio, GO; Menezes, GB; Nogueira, BS; Nogueira, JC; Oliveira, GP; Raizada, MK | 1 |
| Lei, B; Li, Q; Qiu, Y; Shil, PK; Verma, A; Yang, H; Zhu, P | 1 |
| Beck, RC; Da Silva, AS; Dalla Rosa, L; Doyle, RL; França, RT; Gressler, LT; Lopes, ST; Monteiro, SG; Moreira, KL; Oliveira, CB; Oliveira, DT; Ourique, AF; Rigo, LA; Veiga, ML | 1 |
| Cassis, LA; Curci, JA; Daugherty, A; Ennis, T; Gurley, SB; Howatt, DA; Thatcher, SE; Yiannikouris, F; Zhang, X | 1 |
| Bennion, DM; Donnangelo, LL; Haltigan, EA; Irwin, AJ; Pioquinto, DJ; Purich, DL; Regenhardt, RW; Sumners, C | 1 |
| Araújo, TS; Cerqueira, GS; Costa, DS; Martins, CS; Medeiros, JV; Nicolau, LA; Pacífico, DM; Silva, RO; Sousa, FB; Sousa, NA; Souza, FM; Souza, LK; Souza, MH | 1 |
| Amara, VR; Dhawale, VS; Karpe, PA; Malek, V; Patel, D; Tikoo, K | 1 |
| Ademola, IO; Odeniran, PO | 1 |
| Gachie, BM; Kagira, JM; Karanja, SM; Maina, NW; Maranga, DN; Ngotho, M; Waema, MW | 1 |
| Farah, IO; Hau, J; Kagira, JM; Kariuki, C; Maina, N; Mwangangi, DM; Ngotho, M; Thuita, JK | 1 |
| Chitanga, S; Delespaux, V; Marcotty, T; Namangala, B; Van Den Abbeele, J; Van den Bossche, P | 1 |
| Afzal, A; Agarwal, D; Bradford, C; Bruce, E; Cardounel, AJ; Douglas, JY; Ferreira, AJ; Fraga-Silva, RA; Francis, J; Gjymishka, A; Grant, MB; Gupta, D; Jarajapu, YP; Jun, JY; Katovich, MJ; Kearns, P; Kennedy, WR; Mocco, J; Mubarak, KK; Patel, JM; Qi, Y; Raizada, MK; Rathinasabapathy, A; Rigatto, K; Shenoy, V | 1 |
| Clausen, PH; Eisler, MC; McDermott, JJ; Mehlitz, D; Mitema, ES; Olila, D; Patzelt, RJ; Peregrine, AS; Poetzsch, CJ; Zessin, KH | 1 |
| Anene, BM; Barrett, MP; Brock, JM; De Koning, HP; Ezeokonkwo, RC; Mmesirionye, TI; Tettey, JN | 1 |
| Burke, J; Eckersall, PD; Jennings, FW; Mburu, J; Mungatana, N; Murray, M; Ngure, RM | 1 |
| Gray, JS | 1 |
| Abebe, G; Afewerk, Y; Clausen, PH; Mehlitz, D; Tilahun, G | 1 |
| Bradley, B; Eckersall, PD; Gow, JW; Kennedy, PG; McComb, C; Murray, M; Rodgers, J | 1 |
| Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M | 1 |
| Gannon, P; Gray, JS | 1 |
| Akiba, M; Ishii, T; Saeki, H; Ueda, K; Yamamoto, S | 1 |
| Clarkson, AB; Rosenberg, C; Williams, DE | 1 |
33 other study(ies) available for diminazene aceturate and Disease Models, Animal
| Article | Year |
|---|---|
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Nitroimidazoles; Small Molecule Libraries; Structure-Activity Relationship; Trypanosomiasis, African | 2018 |
ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloidogenic Proteins; Angiotensin-Converting Enzyme 2; Animals; Cognitive Dysfunction; Diminazene; Disease Models, Animal; Mice; Mice, Transgenic; Proto-Oncogene Mas | 2020 |
Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Formaldehyde; Humans; Injections, Spinal; Male; Mice; Microglia; Neurons; Nociception; p38 Mitogen-Activated Protein Kinases; Pain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Spinal Cord | 2020 |
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Airway Obstruction; Animals; Animals, Newborn; Bicarbonates; Bronchi; Bronchoalveolar Lavage Fluid; Chlorides; Cystic Fibrosis; Diminazene; Disease Models, Animal; Female; Gene Expression; Humans; Hydrogen-Ion Concentration; Male; Mucin 5AC; Mucin-5B; Mucociliary Clearance; Mucus; Respiratory Mucosa; Swine; Trachea | 2020 |
The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activators; Humans; Hypertension, Pulmonary; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Dysfunction, Left | 2020 |
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence | 2020 |
Diminazene Aceturate Stabilizes Atherosclerotic Plaque and Attenuates Hepatic Steatosis in apoE-Knockout Mice by Influencing Macrophages Polarization and Taurine Biosynthesis.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Diet, High-Fat; Diminazene; Disease Models, Animal; Fatty Liver; Female; Gene Expression Regulation; Humans; Liver; Macrophage Activation; Macrophages; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Peptide Fragments; Plaque, Atherosclerotic; Taurine; THP-1 Cells | 2021 |
Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice.
Topics: Adrenocorticotropic Hormone; Angiotensin-Converting Enzyme 2; Animals; Anxiety; Corticotropin-Releasing Hormone; Diminazene; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activators; Hormones; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Pituitary Gland; Pituitary-Adrenal System; Pro-Opiomelanocortin; RNA, Messenger; Stress, Psychological | 2018 |
ACE2 activator diminazene aceturate reduces adiposity but preserves lean mass in young and old rats.
Topics: Adiposity; Age Factors; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Gene Expression; Male; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred F344; Renin-Angiotensin System | 2018 |
Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B.
Topics: Animals; Arsenicals; Diminazene; Disease Models, Animal; Ethiopia; Female; Injections; Mice; Phenanthridines; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2018 |
Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Babesia; Babesiosis; Benzoquinones; Diminazene; Disease Models, Animal; Female; Inhibitory Concentration 50; Mice; Phytochemicals; Theileria; Theileriasis | 2019 |
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Caspase 3; Cell Count; Diminazene; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Male; Nerve Fibers; Ophthalmic Solutions; Optic Nerve; Peptide Fragments; Peptidyl-Dipeptidase A; Radionuclide Imaging; Rats; Rats, Wistar; Renin-Angiotensin System; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Tonometry, Ocular | 2013 |
Angiotensin-converting enzyme 2 (ACE2) activator diminazene aceturate ameliorates endotoxin-induced uveitis in mice.
Topics: Angiotensin-Converting Enzyme 2; Animals; Anterior Eye Segment; Diminazene; Disease Models, Animal; Enzyme Activation; Female; Follow-Up Studies; Intercalating Agents; Mice; Mice, Inbred BALB C; Ophthalmic Solutions; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Uveitis | 2014 |
Diminazene aceturate liposomes: morphometric and biochemical liver, kidney, and spleen of rats infected with Trypanosoma evansi.
Topics: Animals; Biomarkers; Diminazene; Disease Models, Animal; Kidney; Kidney Function Tests; Liposomes; Liver; Liver Function Tests; Male; Rats, Wistar; Spleen; Time Factors; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2014 |
Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aortic Aneurysm, Abdominal; Diminazene; Disease Models, Animal; Enzyme Activation; Female; Humans; Hypercholesterolemia; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Peptidyl-Dipeptidase A; Receptors, LDL; Renin-Angiotensin System; RNA, Messenger | 2014 |
Activation of the Neuroprotective Angiotensin-Converting Enzyme 2 in Rat Ischemic Stroke.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Corpus Striatum; Diminazene; Disease Models, Animal; Endothelin-1; Enzyme Activation; Imidazoles; Infarction, Middle Cerebral Artery; Infusions, Intraventricular; Leucine; Male; Neuroprotective Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger | 2015 |
Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.
Topics: Acetic Acid; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Ethanol; Female; Gastric Mucosa; Male; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Stomach Ulcer | 2016 |
Activation of angiotensin-converting enzyme 2 (ACE2) attenuates allergic airway inflammation in rat asthma model.
Topics: Angiotensin-Converting Enzyme 2; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Diminazene; Disease Models, Animal; Glutathione; I-kappa B Proteins; Interleukin-1beta; Interleukin-4; Leukocyte Count; Lung; Male; Malondialdehyde; Myocardium; NF-kappa B; Nitric Oxide; Ovalbumin; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar | 2016 |
Novel trypanocide from an extract of Pleurotus sajor-caju against Trypanosoma congolense.
Topics: Animals; Biomarkers; Body Weight; Diminazene; Disease Models, Animal; Dose-Response Relationship, Drug; Mice, Inbred BALB C; Parasitemia; Pleurotus; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2017 |
IgM, lgG and IL-6 profiles in the Trypanosoma brucei brucei monkey model of human African trypanosomiasis.
Topics: Animals; Antigens, Protozoan; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Immunoglobulin G; Immunoglobulin M; Interleukin-6; Trypanosoma brucei brucei; Trypanosomiasis, African | 2017 |
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense.
Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2011 |
High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.
Topics: Africa South of the Sahara; Alleles; Animals; Antiprotozoal Agents; Diminazene; Disease Models, Animal; DNA, Protozoan; Drug Resistance; Mice; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Selection, Genetic; Trypanosoma congolense; Trypanosomiasis, African | 2011 |
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.
Topics: Animals; Cell Migration Assays; Diminazene; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Hypertension, Pulmonary; Male; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stem Cells; Trypanocidal Agents | 2013 |
Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda.
Topics: Animals; Cattle; Diminazene; Disease Models, Animal; Drug Resistance; Ethidium; Female; Goat Diseases; Goats; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda | 2002 |
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.
Topics: Animals; Diminazene; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Female; Parasitic Sensitivity Tests; Pentamidine; Random Allocation; Rats; Recurrence; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2006 |
Acute phase response in mice experimentally infected with Trypanosoma congolense: a molecular gauge of parasite-host interaction.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Anemia; Animals; Diminazene; Disease Models, Animal; Female; Haptoglobins; Hematocrit; Host-Parasite Interactions; Mice; Random Allocation; Serum Amyloid P-Component; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2008 |
Chemotherapy of Babesia divergens in the gerbil, Meriones unguiculatus.
Topics: Animals; Antiprotozoal Agents; Babesiosis; Carbanilides; Diminazene; Disease Models, Animal; Female; Gerbillinae; Imidocarb; Male; Quinolinium Compounds; Urea | 1983 |
Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Ethiopia; Mice; Mice, Inbred BALB C; Parasitemia; Phenanthridines; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2000 |
Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Cytokines; Diminazene; Disease Models, Animal; Encephalitis; Female; Haptoglobins; Mice; Parasitemia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Amyloid P-Component; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2001 |
The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis.
Topics: Animals; Azathioprine; Brain Diseases; Diminazene; Disease Models, Animal; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosomiasis, African | 1992 |
Preliminary development of a live drug-controlled vaccine against bovine babesiosis using the Mongolian gerbil, Meriones unguiculatus.
Topics: Adjuvants, Immunologic; Animals; Babesia; Babesiosis; Cattle; Cattle Diseases; Diminazene; Disease Models, Animal; Female; Gerbillinae; Imidocarb; Levamisole; Male; Oxytetracycline; Propionibacterium acnes; Protozoan Vaccines; Splenectomy; Vaccination; Virulence | 1992 |
Immunological changes in Babesia rodhaini infected BALB/c mice after treated with anti-babesial drug; diminazene diaceturate.
Topics: Acute Disease; Animals; Antibodies, Protozoan; Babesia; Babesiosis; Diminazene; Disease Models, Animal; Disease Susceptibility; Enzyme-Linked Immunosorbent Assay; Female; Immunity, Cellular; Immunotherapy, Adoptive; Mice; Mice, Inbred BALB C; Mice, Nude; Recurrence; Spleen; Thymus Gland | 1991 |
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dapsone; Diminazene; Disease Models, Animal; Drug Combinations; Eflornithine; Female; Immunosuppression Therapy; Pneumonia, Pneumocystis; Random Allocation; Rats; Rats, Inbred Strains; Sulfamethoxazole; Suramin; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |