diminazene aceturate has been researched along with African Sleeping Sickness in 171 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (32.16) | 18.7374 |
| 1990's | 52 (30.41) | 18.2507 |
| 2000's | 21 (12.28) | 29.6817 |
| 2010's | 36 (21.05) | 24.3611 |
| 2020's | 7 (4.09) | 2.80 |
| Authors | Studies |
|---|---|
| Cerami, A; Ulrich, P | 1 |
| Barrett, MP; Brun, R; Dardonville, C; Kaiser, M; Tanious, F; Wilson, WD | 1 |
| Buckner, FS; Creason, SA; Gelb, MH; Gillespie, JR; Herbst, ZM; Hulverson, MA; McQueen, J; Patrick, DA; Ranade, RM; Tidwell, RR | 1 |
| Bacchi, CJ; Braillard, S; Chatelain, E; Denny, WA; Gaukel, E; Launay, D; Maes, L; Marshall, AJ; Mowbray, CE; Thompson, AM; Wring, SA; Yarlett, N | 1 |
| Comini, MA; Franco, J; Scarone, L | 1 |
| Balabadi, D; Essodina, T; Martin Bienvenu, S; Soudah, B; Toï, N; Wendemanegde Ernest, S; Yao, L | 1 |
| Erin, JP; Kolawole, BJ; Nwoha, RIO; Orakpoghenor, O | 1 |
| Ekloh, W; Gwira, TM; Sunter, JD | 1 |
| Alusi, PM; Auma, JE; Chemuliti, JK; Kurgat, RK; Mdachi, RE; Mugunieri, LG; Mukiria, PW; Ogolla, KO; Okoth, SO; Wamwiri, FN; Wanjala, KB | 1 |
| Farikou, O; Kamga, RMN; Magang, MEK; Mewamba, EM; Ravel, S; Simo, G; Tiofack, AAZ; Tume, C | 1 |
| Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK | 1 |
| Inoue, N; Molefe, NI; Suganuma, K | 1 |
| Adeleye, AI; Adeleye, OE; Adeyemi, SO; Ale, JM; Durotoye, LA; Olukunle, JO; Sogebi, EOA | 1 |
| Adam, Y; Bayala, B; Belem, AMG; Bengaly, Z; Cecchi, G; Delespaux, V; Sidibé, I; Somda, MB; Têko-Agbo, A; Van Den Abbeele, J; Vitouley, SH; Zongo, A | 1 |
| Batawui, K; Bauer, B; Clausen, PH; Delespaux, V; Den Abbeele, JV; Hoppenheit, A; Kulo, AE; Tchamdja, E | 1 |
| Jia, P; Kuriakose, SM; Onyilagha, C; Singh, R; Uzonna, JE | 1 |
| Waiswa, C; Wangoola, MR | 1 |
| Ademola, IO; Macleod, ET; Odeniran, PO; Welburn, SC | 1 |
| Adjimani, JP; Amisigo, CM; Antwi, CA; Gwira, TM | 1 |
| Ezeh, IO; Ezeokonkwo, RC; Idika, IK; Iheagwam, CN; Obi, CF; Obidike, RI; Omoja, VU | 1 |
| Aluwong, T; Ambali, SF; Ayo, JO; Kobo, PI; Maikai, V; Zezi, AU | 1 |
| Isaac, AO; Nyariki, JN; Rashid, K; Wachira, FN | 1 |
| Asres, K; Bisrat, D; Terefe, G; Tewabe, Y | 1 |
| Feyera, T; Shibeshi, W; Terefe, G | 1 |
| Chekwube, AI; Ezeokonkwo, RC; Ikenna, UE; Onyema, EI | 1 |
| Hatendorf, J; Kabasa, JD; Muhanguzi, D; Picozzi, K; Thrusfield, M; Waiswa, C; Welburn, SC | 2 |
| De Deken, R; Delespaux, V; Duchateau, L; Moti, Y; Thys, E; Van Den Abbeele, J | 1 |
| Abebe, G; Barry, D; Dagnachew, S; Goddeeris, B; McCulloch, R; Terefe, G | 1 |
| Bockstal, V; Cnops, J; De Trez, C; Magez, S; Miquel, MC; Radwanska, M | 1 |
| Ademola, IO; Odeniran, PO | 1 |
| Gachie, BM; Kagira, JM; Karanja, SM; Maina, NW; Maranga, DN; Ngotho, M; Waema, MW | 1 |
| Adjahoutonon, B; Cossic, BGA; Dibanganga, GL; Gloaguen, P; Leroy, P; MacLeod, ET; Maganga, G; Picozzi, K | 1 |
| Adomefa, K; Bankolé, AA; Batawui, K; Cecchi, G; Clausen, PH; De Deken, R; Delespaux, V; Hoppenheit, A; Kulo, AE; Marcotty, T; Tchamdja, E; Van Den Abbeele, J; Vitouley, HS | 1 |
| Delespaux, V; Dinka, H; Geerts, S; Masumu, J; Van den Bossche, P | 1 |
| Aliyu, MM; Ibrahim, UI; Mbaya, AW; Nwosu, CO; Taiwo, VO | 1 |
| Farah, IO; Hau, J; Jensen, HE; Kagira, JM; Karanja, SM; Ngotho, M | 1 |
| Farah, IO; Hau, J; Kagira, JM; Kariuki, C; Maina, N; Mwangangi, DM; Ngotho, M; Thuita, JK | 1 |
| Kumshe, HA; Mbaya, AW; Nwosu, CO | 1 |
| Batista, JS; Bezerra, FS; Câmara, AC; García, HA; Olinda, RG; Rebouças, RE; Rodrigues, CM; Silva, TM; Teixeira, MM; Vale, RG | 1 |
| Anaga, AO; Anika, SM; Asuzu, IU; Ihedioha, TE; Mhomga, LI; Obidike, IR; Omoja, VU; Umeakuana, PU | 1 |
| Chitanga, S; Delespaux, V; Marcotty, T; Namangala, B; Van Den Abbeele, J; Van den Bossche, P | 1 |
| Akoda, GK; Bengaly, Z; De Deken, R; Delespaux, V; Diallo, A; Marcotty, T; Nebié, RL; Ouédraogo, M; Séré, M; Sidibé, I; Sow, A; Van Den Abbeele, J; Van den Bossche, P; Vitouley, HS | 1 |
| Anene, BM; Asuzu, IU; Nweze, NE | 1 |
| Allegye-Cudjoe, E; Bauer, B; Boucoum, Z; Clausen, PH; Diall, O; Diarra, B; Mungube, EO; Randolph, T; Sanogo, Y; Vitouley, HS; Zessin, KH | 1 |
| Bengaly, Z; Delespaux, V; Marcotty, T; Sidibe, I; Van Den Abbeele, J; Vitouley, HS | 1 |
| Adeyemi, OS; Sulaiman, FA | 1 |
| Jia, P; Kuriakose, S; Muleme, HM; Onyilagha, C; Singh, R; Uzonna, JE | 1 |
| Clausen, PH; Eisler, MC; McDermott, JJ; Mehlitz, D; Mitema, ES; Olila, D; Patzelt, RJ; Peregrine, AS; Poetzsch, CJ; Zessin, KH | 1 |
| Gessner, A; Kayser, O; Müller, RH; Olbrich, C | 1 |
| BAUER, F | 1 |
| WHITESIDE, EF | 1 |
| HAWKING, F | 1 |
| HUTCHINSON, MP; WATSON, HJ | 1 |
| Jooste, R; Lumamba, D; Mubanga, J; Munsimbwe, L; Van den Bossche, P | 1 |
| Anderson, LF; Barrett, MP; Burchmore, RJ; de Koning, HP; Stewart, M; Wallace, LJ | 1 |
| Bauer, B; Clausen, PH; Gall, Y; McDermott, J; Mehlitz, D; Sidibe, I; Woitag, T | 1 |
| Magona, JW; Mayende, JS; Okiria, R; Okuna, NM | 1 |
| d'Ieteren, GD; McDermott, JJ; Mulatu, W; Nagda, SM; Rowlands, GJ; Schukken, YH; van Schaik, G | 1 |
| Anene, BM; Barrett, MP; Brock, JM; De Koning, HP; Ezeokonkwo, RC; Mmesirionye, TI; Tettey, JN | 1 |
| Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L | 1 |
| Akinwale, OP; Edeghere, HU; Esievo, KA; Nock, IH; Olukosi, YA | 1 |
| Jamal, S; Macuamule, C; Marcotty, T; Neves, L; Penzhorn, BL; Sigauque, I; Van Den Bossche, P | 1 |
| Batista, JS; Madruga, CR; Maia, TF; Riet-Correa, F; Simões, SD; Teixeira, MM | 1 |
| Kagira, JM; Maina, N | 1 |
| Burke, J; Eckersall, PD; Jennings, FW; Mburu, J; Mungatana, N; Murray, M; Ngure, RM | 1 |
| Gray, GD; Hajduk, SL; Jennings, FW | 1 |
| Gray, GD; Jennings, FW; Whitelaw, DD | 1 |
| Mansfield, JM; Sizemore, RC | 1 |
| Abaru, DE; Isakina, D; Liwo, DA; Okori, EE | 1 |
| Chumo, DA; Wellde, BT | 1 |
| Küpper, W; Wolters, M | 1 |
| Jennings, FW; Urquhart, GM | 1 |
| Gilbert, RJ | 1 |
| Craig, TM; Goodwin, JT; Logan, LL; Tembely, S | 1 |
| Emerole, GO; Thabrew, MI | 1 |
| Gray, GD; Jennings, FW | 1 |
| Beckers, A; Gigase, P; Mulumba, P; Van Marck, EA; Wéry, M | 1 |
| Akpavie, SO; Ikede, BO | 1 |
| Gilbert, RJ; Newton, BA | 1 |
| Joshua, RA | 1 |
| Adam, SE; Elamin, EA; Homeida, AM; Mahmoud, MM | 1 |
| Jennings, FW; Miller, BM; Murray, PK; Urquhart, GM | 1 |
| Boo, KS; Forsberg, CM; Mills, JN; Valli, VE | 1 |
| Cagnolati, V; Mdachi, RE; Murilla, GA; Omukuba, JN | 1 |
| Antia, RE; Egbe-Nwiyi, TN | 2 |
| d'Ieteren, GD; Mulatu, W; Nagda, SM; Rowlands, GJ | 1 |
| Mamman, M; Murphy, NB; Peregrine, AS; Williams, DJ | 1 |
| Mabbott, NA; Sternberg, JM; Sutherland, IA | 1 |
| Mamman, M; Peregrine, AS | 1 |
| Gray, MA; Kimarua, RW; Peregrine, AS; Stevenson, P | 1 |
| Kihurani, DO; Mbithi, PM; Mbiuki, SM; Mogoa, E; Nantulya, VM; Nguhiu-Mwangi, J | 1 |
| Mamman, M; Moloo, SK; Peregrine, AS | 1 |
| Bacchi, CJ; Clarkson, AB; Goldberg, B; McCann, PP; Nathan, HC; Saric, M; Sjoerdsma, A; Yarlett, N | 1 |
| Katende, J; Mamman, M; Moloo, SK; Peregrine, AS | 1 |
| Anika, SM; Asuzu, IU; Odika, IE | 2 |
| Logan-Henfrey, L; McOdimba, F; Mwangi, SM | 1 |
| Agbe, A; Yielding, KL | 1 |
| Bwangamoi, O; Joshua, RA; Mandebvu, E; Obwolo, MJ | 1 |
| Authié, E; Coulibaly, L; d'Ieteren, GD; Hecker, PA; Leak, SG; Rowlands, GJ | 1 |
| Diack, A; Moloo, SK; Peregrine, AS | 1 |
| Holmes, PH; Katunguka-Rwakishaya, E; Murray, M | 1 |
| Burke, JM; Gichuki, CW; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M; Rodgers, J | 1 |
| Enyaru, JC; Kaminsky, R; Lubega, GW; Matovu, E | 1 |
| Gordon, JR; Kaushik, RS; Tabel, H; Uzonna, JE | 2 |
| Dolan, RB; Munga, L; Ndung'u, EK; Rossiter, PB; Stevenson, P | 1 |
| Amsler-Delafosse, S; Bauer, B; Kaboré, I; Kamuanga, M | 1 |
| Geerts, S; Goossens, B; Ndao, M; Osaer, S; Van Winghem, J | 1 |
| Dávila, AM; Ortiz, AG; Pereira, SR; Ramirez, L; Silva, RA; Souza, SS | 1 |
| Büscher, P; Faye, JA; Mattioli, RC | 1 |
| Abebe, G; Afewerk, Y; Clausen, PH; Mehlitz, D; Tilahun, G | 1 |
| Bradley, B; Eckersall, PD; Gow, JW; Kennedy, PG; McComb, C; Murray, M; Rodgers, J | 1 |
| Abebe, G; Assefa, E | 1 |
| Abdel Karim, EI; Mohamed-Ahmed, MM; Rahman, AH | 1 |
| Ainanshe, OA; Holmes, PH; Jennings, FW | 1 |
| Löhr, KF; Maloo, SH; Mbura, RJ; Münstermann, S | 1 |
| Bruijn, JA; Fleuren, GJ; van Leer, EH; van Velthuysen, ML | 1 |
| Claxton, JR; Dwinger, RH; Leperre, P; Rawlings, P; Snow, WF | 1 |
| Adams, JH; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M | 1 |
| Bauer, B; Clausen, PH; Kaboré, I; Sidibe, I | 1 |
| Arakawa, A; Chitambo, H; Ono, T | 1 |
| Aliu, YO; Gray, MA; Mamman, M; Moloo, SK; Peregrine, AS; Silayo, RS | 1 |
| Munyua, WK; Njogu, AR; Olaho-Mukani, W | 1 |
| Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M | 1 |
| Jennings, FW | 2 |
| Kaminsky, R; Zweygarth, E | 2 |
| Egwu, GO; Onyeyili, PA; Orjiude, BA; Zaria, LT | 1 |
| Onwualu, JE; Onyeyili, PA | 1 |
| Arakawa, A; Chitambo, H | 1 |
| Gettinby, G; McOdimba, FA; Moloo, SK; Murray, M; Paling, RW; Scott, JR | 1 |
| Alushula, H; Dolan, RB; Mutugi, M; Njogu, AR; Okech, G; Sayer, PD; Stevenson, P | 1 |
| Kaminsky, R; Webster, P; Zweygarth, E | 1 |
| Ibitayo, AI; Knowles, G; Moloo, SK; Murphy, NB; Peregrine, AS; Scott, JR | 1 |
| Hopkins, J; Luckins, AG; Mwangi, DM | 1 |
| Anika, SM; Onyeyili, PA | 2 |
| Chumo, DA; Kamar, KK; Muriithi, RM; Njogu, AR; Onyango, F; Reardon, MJ; Roberts, LM; Wellde, BT | 1 |
| Chumo, DA; Higgs, J; Kovatch, RM; Preston, JM; Wellde, BT | 1 |
| Ibe, CC; Wosu, LO | 1 |
| Rogers, DJ | 1 |
| Jefferies, D; Jenni, L | 2 |
| Brown, HC; Holmes, PH; Jennings, FW; Waitumbi, JN | 1 |
| Lekaki, KA; Mbwambo, HA; Mella, PN | 1 |
| Alushula, H; Gatuta, GM; Mgutu, SP; Njogu, AR; Wilson, AJ | 1 |
| Malu, MN; Tabel, H | 1 |
| Gardiner, PR; Murray, M; Whitelaw, DD | 1 |
| Gardiner, PR; Moloo, SK; Nelson, RT; Vos, GJ | 1 |
| Otesile, EB; Tabel, H | 1 |
| Gardiner, PR; Moloo, SK; Vos, GJ | 1 |
| Kaggwa, E; Mugera, GM; Munyua, WK | 1 |
| Röttcher, D; Zweygarth, E | 1 |
| Moloo, SK; Röttcher, D; Schönefeld, A | 1 |
| Jenni, L; Moloo, SK; Paling, RW | 1 |
| Abebe, G | 1 |
| Bafort, JM; Molyneux, DH; Schmidt, H | 1 |
| Büttner, M; Reiter, I; Seitz, A | 1 |
| Dwinger, RH; Luckins, AG; Moloo, SK; Murray, M; Rae, P | 1 |
| Dehoux, JP; Demey, F; Makumyaviri, AM; Verhulst, A | 1 |
| Black, SJ; Koch, GL; Sendashonga, CN; Shapiro, SZ; Webster, P | 1 |
| Akpavie, SO; Egbunike, GN; Ikede, BO | 1 |
| Akol, GW; Murray, M | 1 |
| Moulton, JE | 1 |
| Mitchell, LA; Pearson, TW | 1 |
| Urquhart, GM; Whitelaw, DD | 1 |
| Bovell, D; Brighouse, G; Poltera, AA; Rudin, W; Sayer, PD | 1 |
2 review(s) available for diminazene aceturate and African Sleeping Sickness
| Article | Year |
|---|---|
Pharmacology of diminazene: a review.
Topics: Animals; Animals, Domestic; Diminazene; Drug Resistance; Drug Therapy, Combination; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 1993 |
Trypanosomiasis 'risk' or 'challenge': a review.
Topics: Africa, Eastern; Africa, Western; Animals; Cattle; Diminazene; Humans; Risk; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1985 |
8 trial(s) available for diminazene aceturate and African Sleeping Sickness
| Article | Year |
|---|---|
Probiotic administration enhanced antitrypanosomal effects of diminazene aceturate in dogs experimentally infected with
Topics: Animals; Diminazene; Dogs; Female; Hemoglobins; Male; Parasitemia; Probiotics; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2022 |
Effects of Trypanosoma brucei infection and diminazene aceturate therapy on testicular morphology and function of Nigerian local dogs.
Topics: Animals; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Male; Nigeria; Parasitemia; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African | 2013 |
Collateral benefits of restricted insecticide application for control of African trypanosomiasis on Theileria parva in cattle: a randomized controlled trial.
Topics: Animals; Cattle; Diminazene; Endemic Diseases; Female; Insecticides; Male; Pyrethrins; Theileria parva; Theileriasis; Trypanocidal Agents; Trypanosomiasis, African | 2014 |
Effects of melarsamine hydrochloride (Cymelarsan) and diminazene aceturate (Berenil) on the pathology of experimental Trypanosoma brucei infection in red fronted gazelles (Gazella rufifrons).
Topics: Animals; Antelopes; Arsenicals; Diminazene; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Is trypanocidal drug resistance a threat for livestock health and production in endemic areas? Food for thoughts from Sahelian goats infected by Trypanosoma vivax in Bobo Dioulasso (Burkina Faso).
Topics: Animals; Burkina Faso; Diminazene; Drug Resistance; Female; Goat Diseases; Goats; Hematocrit; Parasitemia; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2012 |
Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense.
Topics: Animals; Antibodies, Protozoan; Diminazene; Drug Resistance; Flow Cytometry; Goat Diseases; Goats; Male; Phenotype; Trypanosoma congolense; Trypanosomiasis, African | 1995 |
Variation in sensitivity of Trypanosoma congolense to diminazene during the early phase of tsetse-transmitted infection in goats.
Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Diminazene; Drug Administration Schedule; Drug Resistance; Goat Diseases; Goats; Injections, Intramuscular; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1993 |
The influence of supplementation with cotton seed cake on the resistance of Ugandan goats to primary and secondary challenges with Trypanosoma congolense and on their response to treatment.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Diminazene; Food, Fortified; Goat Diseases; Goats; Hematocrit; Immunity, Innate; Male; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Uganda | 1997 |
161 other study(ies) available for diminazene aceturate and African Sleeping Sickness
| Article | Year |
|---|---|
Trypanocidal 1,3-arylene diketone bis(guanylhydrazone)s. Structure-activity relationships among substituted and heterocyclic analogues.
Topics: Animals; Drug Evaluation, Preclinical; Female; Guanidines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Mitoguazone; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1984 |
DNA binding affinity of bisguanidine and bis(2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity.
Topics: Animals; DNA; Female; Guanidines; Imidazolines; Mice; Nucleoside Transport Proteins; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2006 |
Urea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis.
Topics: Benzothiazoles; Humans; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Urea | 2017 |
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Nitroimidazoles; Small Molecule Libraries; Structure-Activity Relationship; Trypanosomiasis, African | 2018 |
Novel distamycin analogues that block the cell cycle of African trypanosomes with high selectivity and potency.
Topics: Animals; Cell Cycle; Distamycins; Female; Macrophages; Mice; Mice, Inbred BALB C; Thiazoles; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 2020 |
Assessment of α-Cypermethrin Pour-On Application and Diminazene Aceturate for Treating Trypanosome-Related Diseases Caused by Tsetse Flies on Cattle in Mô, Togo.
Topics: Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Heteroptera; Pyrethrins; Togo; Trypanosoma; Trypanosomiasis, African; Tsetse Flies | 2022 |
African trypanosome infection patterns in cattle in a farm setting in Southern Ghana.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Farms; Female; Ghana; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2023 |
Variation of sensitivity of Trypanosoma evansi isolates from Isiolo and Marsabit counties of Kenya to locally available trypanocidal drugs.
Topics: Animals; Camelus; Chlorides; Diminazene; Drug Resistance; Kenya; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2023 |
Molecular identification of diminazene aceturate-resistant strains of Trypanosoma congolense in naturally infected domestic animals of Yoko in the centre region of Cameroon.
Topics: Animals; Cameroon; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance; Sheep; Sheep Diseases; Sheep, Domestic; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2020 |
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence | 2020 |
An ATP-Based Luciferase Viability Assay for Animal African Trypanosomes Using a 96-Well Plate.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Diminazene; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Luciferases; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African | 2017 |
Effects of Trypanosoma brucei brucei infection and diminazene aceturate administration on the blood pressure, heart rate, and temperature of Wistar albino rats.
Topics: Animals; Blood Pressure; Body Temperature; Diminazene; Heart Rate; Male; Rats; Rats, Wistar; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2018 |
Drug quality analysis of isometamidium chloride hydrochloride and diminazene diaceturate used for the treatment of African animal trypanosomosis in West Africa.
Topics: Africa, Western; Animals; Chromatography, High Pressure Liquid; Diminazene; Livestock; Phenanthridines; Quality Control; Trypanocidal Agents; Trypanosomiasis, African | 2018 |
How rational drug use reduces trypanosome infections in cattle in chemo-resistance hot-spot villages of northern Togo.
Topics: Albendazole; Animals; Antimicrobial Stewardship; Cattle; Diminazene; Drug Resistance; Insecticides; Male; Phenanthridines; Ticks; Togo; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2019 |
Diminazene aceturate (Berenil) downregulates Trypanosoma congolense-induced proinflammatory cytokine production by altering phosphorylation of MAPK and STAT proteins.
Topics: Animals; Cattle; Cell Line, Transformed; Cytokines; Diminazene; Female; Humans; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2019 |
Sustaining Efforts of Controlling Zoonotic Sleeping Sickness in Uganda Using Trypanocidal Treatment and Spray of Cattle with Deltamethrin.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Humans; Insect Vectors; Insecticides; Nitriles; Pyrethrins; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies; Uganda; Zoonoses | 2019 |
Suspected resistance of Trypanosoma species to diminazene aceturate on a cattle farm in Nigeria.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Intergenic; Drug Resistance; Farms; Nigeria; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2019 |
In vitro anti-trypanosomal effects of selected phenolic acids on Trypanosoma brucei.
Topics: Animals; Cell Proliferation; Cell Survival; Deferoxamine; Diminazene; Drug Resistance; Gallic Acid; Humans; Hydroxybenzoates; Iron; Mitochondrial Membranes; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 2019 |
Flavonoid mixture ameliorates increase in erythrocyte osmotic fragility and malondialdehyde concentration induced by Trypanosoma brucei brucei-infection in Wistar rats.
Topics: Animals; Diminazene; Diosmin; Erythrocytes; Male; Malondialdehyde; Osmotic Fragility; Parasitemia; Random Allocation; Rats; Rats, Wistar; Trypanosoma brucei brucei; Trypanosomiasis, African | 2014 |
Kenyan purple tea anthocyanins and coenzyme-Q10 ameliorate post treatment reactive encephalopathy associated with cerebral human African trypanosomiasis in murine model.
Topics: Animals; Anthocyanins; Body Weight; Central Nervous System Diseases; Diminazene; Female; Hematocrit; Humans; Mice; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Ubiquinone | 2014 |
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate.
Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
Evaluation of in vivo antitrypanosomal activity of crude extracts of Artemisia abyssinica against aTrypanosoma congolense isolate.
Topics: Animals; Artemisia; Diminazene; Female; Humans; Male; Mice; Parasitemia; Phytotherapy; Plant Components, Aerial; Plant Extracts; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
Effect of diminazene aceturate, levamisole and vitamin C combination therapy in rats experimentally infected with Trypanosoma brucei brucei.
Topics: Animals; Ascorbic Acid; Body Temperature; Body Weight; Diminazene; Drug Therapy, Combination; Hemoglobins; Leukocyte Count; Levamisole; Male; Parasite Load; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2014 |
Improvements on restricted insecticide application protocol for control of Human and Animal African Trypanosomiasis in eastern Uganda.
Topics: Albendazole; Animals; Cattle; Cattle Diseases; Diminazene; Female; Humans; Insect Control; Insecticides; Male; Population Density; Trypanosomiasis, African; Uganda | 2014 |
PCR and microsatellite analysis of diminazene aceturate resistance of bovine trypanosomes correlated to knowledge, attitude and practice of livestock keepers in South-Western Ethiopia.
Topics: Agriculture; Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Ethiopia; Health Knowledge, Attitudes, Practice; Livestock; Longitudinal Studies; Microsatellite Repeats; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2015 |
In vivo experimental drug resistance study in Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Communicable Diseases; Diminazene; Drug Resistance; Ethiopia; Insect Vectors; Male; Parasitemia; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Tsetse Flies | 2015 |
Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments.
Topics: Animals; B-Lymphocyte Subsets; Bone Marrow; Diminazene; Female; Lymphopoiesis; Mice; Mice, Inbred C57BL; Spleen; Suramin; Trypanocidal Agents; Trypanosomiasis; Trypanosomiasis, African | 2015 |
Novel trypanocide from an extract of Pleurotus sajor-caju against Trypanosoma congolense.
Topics: Animals; Biomarkers; Body Weight; Diminazene; Disease Models, Animal; Dose-Response Relationship, Drug; Mice, Inbred BALB C; Parasitemia; Pleurotus; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2017 |
IgM, lgG and IL-6 profiles in the Trypanosoma brucei brucei monkey model of human African trypanosomiasis.
Topics: Animals; Antigens, Protozoan; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Immunoglobulin G; Immunoglobulin M; Interleukin-6; Trypanosoma brucei brucei; Trypanosomiasis, African | 2017 |
Trypanosomiasis challenge estimation using the diminazene aceturate (Berenil) index in Zebu in Gabon.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Gabon; Longitudinal Studies; Rain; Seasons; Tropical Climate; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2017 |
Cattle breeding, trypanosomosis prevalence and drug resistance in Northern Togo.
Topics: Animals; Breeding; Cattle; Cattle Diseases; Communicable Disease Control; Cross-Sectional Studies; Diminazene; Drug Resistance; Phenanthridines; Prevalence; Togo; Treatment Failure; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2017 |
Five-fold increase in Trypanosoma congolense isolates resistant to diminazene aceturate over a seven-year period in Eastern Zambia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Protozoan; Dose-Response Relationship, Drug; Drug Resistance; Mice; Mice, Inbred Strains; Polymorphism, Restriction Fragment Length; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zambia | 2008 |
Immunospecific immunoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys.
Topics: Animals; Antigens, Protozoan; Biomarkers; Brain; Chlorocebus aethiops; Diminazene; Female; Immunoglobulin G; Immunoglobulin M; Interleukin-10; Male; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2009 |
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense.
Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2011 |
Genital lesions in male red fronted gazelles (Gazella rufifrons) experimentally infected with Trypanosoma brucei and the effect of melarsamine hydrochloride (Cymelarsan®) and diminazene aceturate (Berenil®) in its treatment.
Topics: Animals; Antelopes; Arsenicals; Body Temperature; Diminazene; Genital Diseases, Male; Hematocrit; Histocytochemistry; Male; Parasitemia; Semen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2011 |
Highly debilitating natural Trypanosoma vivax infections in Brazilian calves: epidemiology, pathology, and probable transplacental transmission.
Topics: Animals; Antiprotozoal Agents; Brazil; Cattle; Cattle Diseases; Diminazene; Infectious Disease Transmission, Vertical; Parasitemia; Prevalence; Severity of Illness Index; Survival Analysis; Trypanosoma vivax; Trypanosomiasis, African | 2012 |
The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats.
Topics: Animals; Azadirachta; Diminazene; Drug Resistance; Drug Therapy, Combination; Female; Male; Parasitemia; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Trypanosoma brucei brucei; Trypanosomiasis, African | 2011 |
High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.
Topics: Africa South of the Sahara; Alleles; Animals; Antiprotozoal Agents; Diminazene; Disease Models, Animal; DNA, Protozoan; Drug Resistance; Mice; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Selection, Genetic; Trypanosoma congolense; Trypanosomiasis, African | 2011 |
Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Cross-Sectional Studies; Diminazene; Longitudinal Studies; Phenanthridines; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2012 |
Investigation of the antitrypanosomal activity of Buchholzia coriacea seed extract against a field strain of Trypanosoma congolense.
Topics: Administration, Oral; Animals; Capparaceae; Diminazene; Dose-Response Relationship, Drug; Female; Hematocrit; Male; Methanol; Mice; Parasitemia; Phytotherapy; Plant Extracts; Seeds; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2011 |
Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali.
Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Mali; Phenanthridines; Rural Population; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 2012 |
Biochemical and morphological changes in Trypanosoma brucei brucei-infected rats treated with homidium chloride and diminazene aceturate.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Diminazene; Ethidium; Male; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2012 |
Diminazene aceturate (Berenil) modulates the host cellular and inflammatory responses to Trypanosoma congolense infection.
Topics: Animals; Cytokines; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Forkhead Transcription Factors; Immunity, Cellular; Inflammation; Interleukin-2 Receptor alpha Subunit; Kupffer Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Spleen; T-Lymphocytes; Trypanosoma congolense; Trypanosomiasis, African | 2012 |
Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda.
Topics: Animals; Cattle; Diminazene; Disease Models, Animal; Drug Resistance; Ethidium; Female; Goat Diseases; Goats; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda | 2002 |
Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate.
Topics: Blood-Brain Barrier; Diminazene; Drug Carriers; Drug Compounding; Drug Stability; Humans; Lipids; Microspheres; Nanotechnology; Particle Size; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Trypanocidal Agents; Trypanosomiasis, African | 2002 |
[Trypanosomiasis and babesiasis in Africa and their treatment with the new preparation berenil].
Topics: Africa; Amidines; Aniline Compounds; Animals; Apicomplexa; Babesiosis; Cattle; Cattle Diseases; Coloring Agents; Diminazene; Dog Diseases; Dogs; Infections; Trypanosomiasis; Trypanosomiasis, African | 1955 |
A strain of Trypanosoma congolense directly resistant to berenil.
Topics: Animals; Antiparasitic Agents; Azo Compounds; Diminazene; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African | 1963 |
DRUG-RESISTANCE OF TRYPANOSOMA CONGOLENSE AND OTHER TRYPANOSOMES TO QUINAPYRAMINE, PHENANTHRIDINES, BERENIL AND OTHER COMPOUNDS IN MICE.
Topics: Animals; Antiprotozoal Agents; Diminazene; Mice; Phenanthridines; Quinolines; Quinolinium Compounds; Research; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African | 1963 |
Berenil in the treatment of Trypanosoma gambiense infection in man.
Topics: Amidines; Aniline Compounds; Animals; Black People; Diminazene; Humans; Trypanosoma brucei gambiense; Trypanosomiasis; Trypanosomiasis, African | 1962 |
A large-scale trial to evaluate the efficacy of a 1% pour-on formulation of cyfluthrin (Cylence, Bayer) in controlling bovine trypanosomosis in Eastern Zambia.
Topics: Administration, Topical; Animals; Cattle; Diminazene; Hematocrit; Incidence; Insecticides; Nitriles; Pyrethrins; Seasons; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Zambia | 2004 |
The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.
Topics: Adenosine; Animals; Biological Transport, Active; Diminazene; Drug Resistance; Female; Kinetics; Mutation; Nucleoside Transport Proteins; Rats; Rats, Wistar; Saccharomyces cerevisiae; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2004 |
Trypanocidal failure suggested by PCR results in cattle field samples.
Topics: Animals; Cattle; Diminazene; Drug Resistance, Microbial; Parasitic Sensitivity Tests; Phenanthridines; Polymerase Chain Reaction; Sensitivity and Specificity; Treatment Failure; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2004 |
Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda.
Topics: Animals; Cattle; Diminazene; Female; Insect Control; Male; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Uganda | 2004 |
Transition models to assess risk factors for new and persistent trypanosome infections in cattle-analysis of longitudinal data from the Ghibe Valley, southwest Ethiopia.
Topics: Age Factors; Animals; Cattle; Diminazene; Ethiopia; Female; Incidence; Insect Control; Insect Vectors; Longitudinal Studies; Male; Models, Biological; Odds Ratio; Prevalence; Recurrence; Risk Factors; Seasons; Sensitivity and Specificity; Sex Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 2004 |
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.
Topics: Animals; Diminazene; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Female; Parasitic Sensitivity Tests; Pentamidine; Random Allocation; Rats; Recurrence; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2006 |
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.
Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2006 |
Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection.
Topics: Animals; Diminazene; Disease Susceptibility; Goat Diseases; Goats; Male; Nigeria; Parasitemia; Random Allocation; Treatment Outcome; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2006 |
The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride.
Topics: Animals; Diminazene; Drug Resistance; Ethidium; Mice; Mozambique; Parasitic Sensitivity Tests; Phenanthridines; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2005 |
Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system.
Topics: Abortion, Veterinary; Animals; Antibodies, Protozoan; Brain; Brazil; Cattle; Cattle Diseases; Diminazene; Disease Outbreaks; Female; Nervous System; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2007 |
Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients.
Topics: Animals; Diminazene; Drug Resistance, Multiple; Humans; Kenya; Melarsoprol; Mice; Parasitic Sensitivity Tests; Phenanthridines; Random Allocation; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda | 2007 |
Acute phase response in mice experimentally infected with Trypanosoma congolense: a molecular gauge of parasite-host interaction.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Anemia; Animals; Diminazene; Disease Models, Animal; Female; Haptoglobins; Hematocrit; Host-Parasite Interactions; Mice; Random Allocation; Serum Amyloid P-Component; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2008 |
Relapse of monomorphic and pleomorphic Trypanosoma brucei infections in the mouse after chemotherapy.
Topics: Amidines; Animals; Brain; Diminazene; Female; Mice; Recurrence; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Chemotherapy of Trypanosoma brucei in mice with diminazene aceturate. Variation in the aparasitaemic period over 5 years.
Topics: Amidines; Animals; Blood; Diminazene; Freezing; Mice; Preservation, Biological; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Lymphocyte function in experimental African trypanosomiasis. VII. Loss of antigen-nonspecific suppressor-T-cell activity.
Topics: Animals; Antibody Formation; Antigens, Ly; Diminazene; Immune Tolerance; Male; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes, Regulatory; Trypanosoma; Trypanosomiasis, African | 1984 |
Retrospective long-term study of effects of berenil by follow-up of patients treated since 1965.
Topics: Adolescent; Adult; Amidines; Cerebrospinal Fluid; Child; Child, Preschool; Diminazene; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Trypanocidal Agents; Trypanosomiasis, African; Uganda; Urine | 1984 |
Persistence of Berenil in cattle.
Topics: Amidines; Animals; Cattle; Diminazene; Kenya; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1983 |
Observation on drug resistance of Trypanosoma (Nannomonas) congolense and Trypanosoma (Duttonella) vivax in cattle at a feedlot in the Northern Ivory Coast.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Male; Phenanthridines; Quaternary Ammonium Compounds; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1983 |
The use of the 2 substituted 5-nitroimidazole, Fexinidazole (Hoe 239) in the treatment of chronic T. brucei infections in mice.
Topics: Animals; Antiprotozoal Agents; Chronic Disease; Diminazene; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Studies in rabbits on the disposition and trypanocidal activity of the anti-trypanosomal drug, diminazene aceturate (Berenil).
Topics: Amidines; Animals; Diminazene; Kinetics; Rabbits; Tissue Distribution; Trypanosomiasis, African | 1983 |
Maintaining zebu Maure cattle in a tsetse infested area of Mali.
Topics: Animals; Body Weight; Cattle; Diminazene; Female; Male; Mali; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1984 |
Response of the rat's hepatic drug-metabolizing enzyme system to chemotherapy of Trypanosoma b. brucei infections with Berenil and Suramin.
Topics: Amidines; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Diminazene; Female; Glutamate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Liver; Microsomes, Liver; Phospholipids; Rats; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1984 |
Relapsed parasitaemia following chemotherapy of chronic T. brucei infections in mice and its relation to cerebral trypanosomes.
Topics: Animals; Antiprotozoal Agents; Brain; Chronic Disease; Diminazene; Mice; Recurrence; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Studies of choroid plexus involvement in chronic infections of mice with Trypanosoma brucei gambiense.
Topics: Animals; Antiprotozoal Agents; Choroid Plexus; Chronic Disease; Diminazene; Mice; Nifurtimox; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Delay in resolution of trypanosome-induced genital lesions in male rabbits infected with Trypanosoma brucei and treated with diminazene aceturate.
Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Genital Diseases, Male; Genitalia, Male; Male; Rabbits; Scrotum; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Pharmacokinetics and efficacy of the trypanocide diminazene aceturate (Berenil) in rabbits.
Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Kinetics; Rabbits; Trypanosomiasis, African | 1982 |
Diminazene aceturate in the treatment of experimentally induced Trypanosoma brucei brucei infection in domestic chickens.
Topics: Amidines; Animals; Antiprotozoal Agents; Chickens; Diminazene; Humans; Mice; Poultry Diseases; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
The efficacy of berenil (diminazene aceturate) against Trypanosoma evansi infection in mice.
Topics: Amidines; Animals; Antiprotozoal Agents; Blood; Diminazene; Female; Male; Mice; Mice, Inbred Strains; Species Specificity; Trypanosoma; Trypanosomiasis, African | 1982 |
'Berenil' and nitroimidazole combinations in the treatment of Trypanosoma brucei infection with central nervous system involvement.
Topics: Amidines; Animals; Benzamidines; Central Nervous System Diseases; Diminazene; Ethidium; Female; Isoxazoles; Mice; Nitroimidazoles; Phenanthridines; Ronidazole; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1980 |
The quantitation of trypanosoma congolense in calves. III. A quantitative comparison of trypanosomes in jugular vein and microvasculature and tests of dispersing agents.
Topics: Animals; Animals, Newborn; Brain; Capillaries; Cattle; Dexamethasone; Diminazene; Jugular Veins; Liver; Male; Muscles; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1980 |
Disposition of diminazene aceturate (Berenil) in trypanosome-infected pregnant and lactating cows.
Topics: Animals; Animals, Suckling; Cattle; Diminazene; Female; Lactation; Milk; Pregnancy; Pregnancy Complications, Parasitic; Tissue Distribution; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1995 |
Use of monoclonal antibodies for detecting T brucei brucei infection in splenectomised dogs.
Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Male; Splenectomy; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1995 |
Variations in packed red cell volume and trypanosome prevalence and relationships with reproductive traits in east African Zebu cows exposed to drug-resistant trypanosomes.
Topics: Abortion, Veterinary; Animals; Cattle; Diminazene; Drug Resistance; Ethiopia; Female; Hematocrit; Incidence; Lactation; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Reproduction; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1995 |
Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivo.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Diminazene; DNA Damage; Female; Immune Tolerance; Immunotherapy, Adoptive; Lymphocyte Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Nitric Oxide; Spleen; T-Lymphocytes; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
Drug sensitivity screening in vitro of populations of Trypanosoma congolense originating from cattle and tsetse flies at Nguruman, Kenya.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1993 |
Trypanosoma brucei, T. congolense and T. vivax infections in horses on a farm in Kenya.
Topics: Animals; Diminazene; Disease Outbreaks; Horse Diseases; Horses; Kenya; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African | 1994 |
Relapse of Trypanosoma congolense infection in goats after diminazene aceturate is not a result of invasion of the central nervous system.
Topics: Animals; Diminazene; Goat Diseases; Goats; Male; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1994 |
Combination chemotherapy of drug-resistant Trypanosoma brucei rhodesiense infections in mice using DL-alpha-difluoromethylornithine and standard trypanocides.
Topics: Animals; Arsenicals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Eflornithine; Female; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1994 |
The effect of trypanocidal drug treatment on the haematological changes in Trypanosoma brucei brucei infected splenectomised dogs.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Diminazene; Dog Diseases; Dogs; Erythrocyte Count; Erythrocyte Indices; Female; Hematocrit; Hemoglobins; Leukocyte Count; Male; Reticulocytes; Splenectomy; Trypanosoma brucei brucei; Trypanosomiasis, African | 1993 |
The chemotherapeutic efficacy of diminazene aceturate and lithium chloride against relapse infection of Trypanosoma brucei brucei in rats.
Topics: Animals; Blood-Brain Barrier; Dexamethasone; Diminazene; Drug Therapy, Combination; Female; Lithium Chloride; Male; Parasitemia; Rats; Rats, Wistar; Recurrence; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
The effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations.
Topics: Acute-Phase Reaction; Animals; Diminazene; Hematocrit; Iron; Leukocyte Count; Male; Rabbits; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Zinc | 1995 |
Kinetoplasts play an important role in the drug responses of Trypanosoma brucei.
Topics: Acriflavine; Animals; Azides; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Ethidium; Female; Light; Mice; Mitochondria; Mitoguazone; Mutation; Parasitemia; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
The effects of hyperosmolar agents lithium chloride and sucrose on the brain concentration of diminazene aceturate in rats.
Topics: Animals; Blood-Brain Barrier; Brain; Diminazene; Female; Lithium Chloride; Male; Permeability; Rats; Rats, Wistar; Sucrose; Tissue Distribution; Trypanocidal Agents; Trypanosomiasis, African | 1995 |
Resistance to diminazine aceturate by Trypanosoma congolense from cattle in the Zambezi Valley of Zimbabwe.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zimbabwe | 1995 |
Effect of tsetse control on trypanosome prevalence in livestock: problems of experimental design and statistical interpretation--a case study in northern Côte d'Ivoire.
Topics: Animal Husbandry; Animals; Cattle; Cote d'Ivoire; Diminazene; Insect Control; Insect Vectors; Sheep; Sheep Diseases; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1996 |
Effect of diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense in Glossina morsitans centralis.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Goats; Insect Vectors; Male; Mice; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1997 |
The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis.
Topics: Animals; Brain; Brain Diseases; Diminazene; Eflornithine; Female; Mice; Mice, Inbred Strains; Polyamines; Putrescine; Trypanocidal Agents; Trypanosomiasis, African | 1997 |
Response of a T. b. rhodesiense stock with reduced drug susceptibility in vitro to treatment in mice and cattle.
Topics: Animals; Cattle; Diminazene; DNA, Protozoan; Drug Resistance; Male; Mice; Phenanthridines; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda | 1998 |
Immunoregulation in experimental murine Trypanosoma congolense infection: anti-IL-10 antibodies reverse trypanosome-mediated suppression of lymphocyte proliferation in vitro and moderately prolong the lifespan of genetically susceptible BALB/c mice.
Topics: Animals; Diminazene; Disease Susceptibility; Female; Interleukin-10; Life Expectancy; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; T-Lymphocytes; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1998 |
Cytokines and antibody responses during Trypanosoma congolense infections in two inbred mouse strains that differ in resistance.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cytokines; Diminazene; Epitopes, B-Lymphocyte; Female; Immunity, Innate; Interferon-gamma; Interleukin-10; Interleukin-4; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; Spleen; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma | 1999 |
Rinderpest vaccination and the incidence and development of trypanosomosis in cattle.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Hematocrit; Incidence; Insect Vectors; Kenya; Male; Neutralization Tests; Rinderpest; Rinderpest virus; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Vaccination; Viral Vaccines | 1999 |
Improvement of cattle productivity through rapid alleviation of African animal trypanosomosis by integrated disease management practices in the agropastoral zone of Yalé, Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Diminazene; Female; Hematocrit; Humans; Insect Control; Insect Vectors; Insecticides; Interviews as Topic; Milk; Nitriles; Pregnancy; Pyrethrins; Seasons; Sentinel Surveillance; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1999 |
The susceptibility of Djallonké and Djallonké-Sahelian crossbred sheep to Trypanosoma congolense and helminth infection under different diet levels.
Topics: Animal Feed; Animals; Anthelmintics; Antibodies, Protozoan; Antiprotozoal Agents; Crosses, Genetic; Diminazene; Disease Susceptibility; Feces; Female; Fenbendazole; Gambia; Helminthiasis, Animal; Helminths; Hematocrit; Male; Nutritional Status; Parasite Egg Count; Parasitemia; Random Allocation; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African | 1999 |
Hematology of natural bovine trypanosomosis in the Brazilian Pantanal and Bolivian wetlands.
Topics: Abortion, Veterinary; Anemia, Hypochromic; Anemia, Macrocytic; Animals; Bolivia; Brazil; Cattle; Diarrhea; Diminazene; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Leukocyte Count; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1999 |
Susceptibility of N'Dama cattle to experimental challenge and cross-species superchallenges with bloodstream forms of Trypanosoma congolense and T. vivax.
Topics: Animals; Cattle; Diminazene; Disease Susceptibility; Gambia; Hematocrit; Male; Parasitemia; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Weight Gain | 1999 |
Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Ethiopia; Mice; Mice, Inbred BALB C; Parasitemia; Phenanthridines; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2000 |
Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Cytokines; Diminazene; Disease Models, Animal; Encephalitis; Female; Haptoglobins; Mice; Parasitemia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Amyloid P-Component; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2001 |
Drug-resistant Trypanosoma congolense in naturally infected donkeys in north Omo Zone, southern Ethiopia.
Topics: Animals; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Equidae; Ethiopia; Female; Male; Mice; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2001 |
Multiple drug-resistant bovine trypanosomes in South Darfur Province, Sudan.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Phenanthridines; Sudan; Time Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Isolation of drug-resistant strains of Trypanosoma congolense from the lower Shabelle region of southern Somalia.
Topics: Animals; Animals, Domestic; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Recurrence; Somalia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Trypanosomiasis control in Boran cattle in Kenya: a comparison between chemoprophylaxis and a parasite detection and intravenous treatment method using isometamidium chloride.
Topics: Animals; Cattle; Diminazene; Drug Administration Schedule; Female; Injections, Intramuscular; Injections, Intravenous; Kenya; Male; Phenanthridines; Risk Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Pathogenesis of trypanosomiasis-induced glomerulonephritis in mice.
Topics: Animals; Antibodies; Basement Membrane; Diminazene; Female; Glomerulonephritis; Kidney Glomerulus; Mice; Mice, Inbred BALB C; Trypanosomiasis, African | 1992 |
Trypanosomiasis in cattle in Gambia: incidence, prevalence and tsetse challenge.
Topics: Animals; Breeding; Cattle; Diminazene; Female; Gambia; Incidence; Insect Vectors; Male; Prevalence; Regression Analysis; Seasons; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1992 |
Subcurative chemotherapy and fatal post-treatment reactive encephalopathies in African trypanosomiasis.
Topics: Adolescent; Adult; Animals; Arsenicals; Brain; Brain Diseases; Child; Child, Preschool; Diminazene; Female; Humans; Male; Mice; Nitroimidazoles; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
Development of multiple drug resistance of Trypanosoma congolense in Zebu cattle under high natural tsetse fly challenge in the pastoral zone of Samorogouan, Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Diminazene; Drug Resistance; Prevalence; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1992 |
In vivo assessment of drug sensitivity of African trypanosomes using the akinetoplastic induction test.
Topics: Animals; Cattle; Diminazene; Mice; Phenanthridines; Rosaniline Dyes; Staining and Labeling; Toluidines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Response of Trypanosoma congolense in goats to single and double treatment with diminazene aceturate.
Topics: Animals; Chromatography, High Pressure Liquid; Diminazene; Drug Administration Schedule; Goat Diseases; Goats; Hematocrit; Lymph Nodes; Male; Skinfold Thickness; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1992 |
An enzyme-linked immunosorbent assay (ELISA) for the detection of trypanosomal antigens in goat serum using a monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Diminazene; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Goats; Immunoglobulin M; Sensitivity and Specificity; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis.
Topics: Animals; Azathioprine; Brain Diseases; Diminazene; Disease Models, Animal; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosomiasis, African | 1992 |
Chemotherapy of CNS-trypanosomiasis: the combined use of diminazene aceturate or pentamidine with DL-alpha-difluoromethylornithine (DFMO).
Topics: Animals; Arsenicals; Central Nervous System Diseases; Diminazene; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Mice; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
Evaluation of DL-alpha-difluoromethylornithine against susceptible and drug-resistant Trypanosoma brucei brucei.
Topics: Animals; Arsenicals; Culture Media; Diminazene; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Humans; Immune Sera; Male; Mice; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
The effect of verapamil alone and in combination with trypanocides on multidrug-resistant Trypanosoma brucei brucei.
Topics: Animals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Female; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Verapamil | 1991 |
DL-alpha-difluoromethylornithine (DFMO)-Berenil combination: therapeutic and prophylactic activity against Trypanosoma brucei brucei infection in mice.
Topics: Animals; Diminazene; Drug Therapy, Combination; Eflornithine; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Efficacy of combination of DFMO and diminazene aceturate in the treatment of late stage Trypanosoma brucei brucei infection in rats.
Topics: Animals; Brain Diseases; Diminazene; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Male; Rats; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Zambia | 1991 |
Susceptibility of N'Dama and Boran cattle to sequential challenges with tsetse-transmitted clones of Trypanosoma congolense.
Topics: Anemia; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Body Weight; Cattle; Diminazene; Disease Susceptibility; Female; Hematocrit; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1991 |
Homidium bromide as a chemoprophylactic for cattle trypanosomiasis in Kenya.
Topics: Animals; Cattle; Diminazene; Ethidium; Hematocrit; Kenya; Male; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Weight Gain | 1990 |
Trypanosoma brucei evansi: dyskinetoplasia and loss of infectivity after long-term in vitro cultivation.
Topics: Animals; Diminazene; DNA, Circular; DNA, Kinetoplast; Female; Male; Mice; Microscopy, Electron; Phenanthridines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1990 |
Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Genetic Variation; Isoenzymes; Mice; Phenanthridines; Phenotype; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1991 |
Cellular phenotypes in Trypanosoma congolense infected sheep: the local skin reaction.
Topics: Animals; Antibodies, Monoclonal; Diminazene; Immunophenotyping; Lymphocyte Subsets; Sheep; Sheep Diseases; Skin; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1990 |
Effects of the combination of DL-alpha-difluoromethylornithine and diminazene aceturate in Trypanosoma congolense infection of dogs.
Topics: Animals; Diminazene; Dog Diseases; Dogs; Drug Therapy, Combination; Eflornithine; Female; Male; Trypanosoma congolense; Trypanosomiasis, African | 1990 |
Natural and acquired resistance to Trypanosoma vivax in cattle.
Topics: Animals; Cattle; Diminazene; Gastrointestinal Hemorrhage; Goats; Immunity, Active; Immunity, Innate; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1989 |
Trypanosoma congolense: erythrocyte indices, plasma iron turnover and effects of treatment in infected cattle.
Topics: Anemia, Hemolytic; Animals; Cattle; Cattle Diseases; Diminazene; Erythrocyte Count; Erythrocyte Indices; Hematocrit; Iron; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1989 |
Use of extracts of Picralima nitida bark in the treatment of experimental trypanosomiasis: a preliminary study.
Topics: Animals; Diminazene; Drug Evaluation, Preclinical; Female; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1989 |
The influence of Trypanosoma congolense infection on the disposition kinetics of diminazene aceturate in the dog.
Topics: Amidines; Animals; Diminazene; Dog Diseases; Dogs; Injections, Intravenous; Male; Regression Analysis; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1989 |
The effect of trypanocidal drugs on the transmission of Trypanosoma brucei brucei by Glossina morsitans centralis.
Topics: Animals; Diminazene; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tsetse Flies | 1987 |
The effect of the trypanocidal drugs berenil and samorin on infections of Glossina morsitans centralis by Trypanosoma congolense.
Topics: Amidines; Animals; Diminazene; Insect Vectors; Male; Mice; Mice, Inbred ICR; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1987 |
The relapse of Trypanosoma brucei brucei infections after chemotherapy in rabbits.
Topics: Amidines; Animals; Diminazene; Female; Male; Mice; Rabbits; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
Berenil (diminazene aceturate)-resistant Trypanosoma congolense in cattle under natural tsetse challenge at Kibaha, Tanzania.
Topics: Amidines; Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Tanzania; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1988 |
A simple epidemiological method for animal trypanosomiasis to provide relevant data for effective financial decision-making.
Topics: Age Factors; Animals; Body Weight; Cattle; Cost-Benefit Analysis; Diminazene; Female; Kenya; Male; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1986 |
The alternative pathway of complement in sheep during the course of infection with Trypanosoma congolense and after Berenil treatment.
Topics: Animals; Antibodies, Bacterial; Brucella abortus; Complement Activation; Complement C3; Complement Factor B; Complement Pathway, Alternative; Diminazene; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African | 1986 |
Extravascular foci of Trypanosoma vivax in goats: the central nervous system and aqueous humor of the eye as potential sources of relapse infections after chemotherapy.
Topics: Animals; Aqueous Humor; Central Nervous System Diseases; Cerebrospinal Fluid; Choroid Plexus; Diminazene; Goats; Male; Mice; Recurrence; Trypanosoma; Trypanosomiasis, African | 1988 |
Attempts to protect goats against challenge with Trypanosoma vivax by initiation of primary infections with large numbers of metacyclic trypanosomes.
Topics: Animals; Antibodies, Protozoan; Diminazene; Goats; Male; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies | 1988 |
Enhanced resistance of highly susceptible Balb/c mice to infection with Trypanosoma congolense after infection and cure.
Topics: Agglutination Tests; Animals; Antibodies, Protozoan; Antigenic Variation; Diminazene; Female; Fluorescent Antibody Technique; Immune Sera; Immunity, Active; Immunization, Passive; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rabbits; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1987 |
Susceptibility of goats to tsetse-transmitted challenge with Trypanosoma vivax from East and West Africa.
Topics: Africa, Eastern; Africa, Western; Animals; Chronic Disease; Diminazene; Disease Susceptibility; Goats; Immunity, Active; Insect Vectors; Male; Recurrence; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies; Virulence | 1988 |
Relapses in dogs experimentally infected with Trypanosoma brucei and treated with diminazene aceturate or isometamidium chloride.
Topics: Alanine Transaminase; Amidines; Animals; Antibodies, Protozoan; Aspartate Aminotransferases; Diminazene; Dog Diseases; Dogs; Fever; Hematocrit; Hemoglobins; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
The treatment of Trypanosoma (Nannomonas) simiae in pigs with diminazene aceturate in combination with a 5-substituted 2-nitroimidazole compound (Ro 15-0216).
Topics: Acetanilides; Amidines; Animals; Diminazene; Drug Therapy, Combination; Female; Male; Mice; Nitroimidazoles; Swine; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 1987 |
The sensitivity to trypanocidal drugs of Trypanosoma vivax isolated in Kenya and Somalia.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Male; Phenanthridines; Quinolinium Compounds; Somalia; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Trypanosoma congolense: host responses following tsetse transmitted infection of Kilifi isolates in goats.
Topics: Animals; Antibody Formation; Antigens, Protozoan; Cattle; Diminazene; Glucose-6-Phosphate Isomerase; Goats; Isoenzymes; Kenya; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1987 |
Failure of berenil therapy to eliminate early infections with a strain of Trypanosoma brucei from West Abaya, Ethiopia.
Topics: Amidines; Animals; Cattle; Diminazene; Ethiopia; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Effect of tetracycline administration on the efficacy of diminazene aceturate therapy and prophylaxis in Trypanosoma brucei infections of mice.
Topics: Amidines; Animals; Diminazene; Drug Therapy, Combination; Mice; Oxytetracycline; Rolitetracycline; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Development of Trypanosoma brucei in suckling mouse brain following intracerebral injection.
Topics: Animals; Animals, Suckling; Brain; Diminazene; Injections, Intraventricular; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Trypanosoma theileri Laveran, 1902, in naturally and experimentally infected cattle: parasite isolation, serological and cellular reactions and Berenil sensitivity.
Topics: Amidines; Animals; Antibodies, Protozoan; Cattle; Diminazene; Immunity, Cellular; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse.
Topics: Animals; Antibody Formation; Diminazene; Goats; Male; Neutralization Tests; Skin; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1986 |
[Duration of the preventive action of diminazene aceturate on experimental infection of NMRI mice with metacyclic forms of Trypanosoma brucei brucei].
Topics: Amidines; Animals; Diminazene; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Regulation of parasite-specific antibody responses in resistant (C57BL/6) and susceptible (C3H/HE) mice infected with Trypanosoma (trypanozoon) brucei brucei.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Diminazene; Disease Susceptibility; Female; Immune Tolerance; Immunity, Innate; Immunoglobulins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Electron; Spleen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Ejaculate characteristics of sheep infected with Trypanosoma brucei and T vivax: changes caused by treatment with diminazene aceturate.
Topics: Animals; Diminazene; Male; Semen; Sheep; Sheep Diseases; Sperm Count; Sperm Motility; Spermatozoa; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Induction of protective immunity in cattle by tsetse-transmitted cloned isolates of Trypanosoma congolense.
Topics: Animals; Antibody Formation; Cattle; Diminazene; Female; Hypersensitivity; Male; Mice; Mice, Inbred A; Neutralization Tests; Skin; Skin Tests; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1985 |
Relapse infection after chemotherapy in goats experimentally infected with Trypanosoma brucei: pathological changes in central nervous system.
Topics: Amidines; Animals; Blood-Brain Barrier; Central Nervous System; Choroiditis; Diminazene; Goats; Male; Meningitis; Orchiectomy; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Antibody responses in resistant and susceptible inbred mice infected with Trypanosoma congolense.
Topics: Animals; Antibody Specificity; Antigens, Protozoan; Antigens, Surface; Diminazene; Disease Susceptibility; Female; Glycoproteins; Immunity, Innate; Immunoglobulin G; Immunoglobulin M; Male; Membrane Proteins; Mice; Mice, Inbred A; Mice, Inbred C57BL; Rats; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma | 1986 |
Maternally derived immunity in young mice to infection with Trypanosoma brucei and its potentiation by Berenil chemotherapy.
Topics: Age Factors; Amidines; Animals; Animals, Suckling; Colostrum; Diminazene; Female; Immunization, Passive; Mice; Pregnancy; Trypanosoma brucei brucei; Trypanosomiasis, African | 1985 |
Immunopathological aspects of trypanosomal meningoencephalitis in vervet monkeys after relapse following Berenil treatment.
Topics: Amidines; Animals; Antigen-Antibody Complex; Autoantibodies; Blood-Brain Barrier; Brain; Chlorocebus aethiops; Diminazene; Immunoglobulin G; Immunoglobulin M; Meningoencephalitis; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1985 |