dimethylphenylpiperazinium iodide has been researched along with Pheochromocytoma in 3 studies
Dimethylphenylpiperazinium Iodide: A selective nicotinic cholinergic agonist used as a research tool. DMPP activates nicotinic receptors in autonomic ganglia but has little effect at the neuromuscular junction.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Carbachol-induced PKC translocation was concentration-dependent, with a biphasic dose-response curve yielding approximate EC50 values of 10(-6) M and 10(-4) M for the high- and low-affinity components, respectively." | 1.28 | Nicotinic and muscarinic agonists stimulate rapid protein kinase C translocation in PC12 cells. ( Kiyasu, E; Messing, RO; Sneade, AB; Stevens, AM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, CL | 1 |
| Chen, HC | 1 |
| Huang, NK | 1 |
| Yang, DM | 1 |
| Kao, LS | 1 |
| Chen, JC | 1 |
| Lai, HL | 1 |
| Chern, Y | 1 |
| Greene, LA | 1 |
| Rein, G | 1 |
| Messing, RO | 1 |
| Stevens, AM | 1 |
| Kiyasu, E | 1 |
| Sneade, AB | 1 |
3 other studies available for dimethylphenylpiperazinium iodide and Pheochromocytoma
| Article | Year |
|---|---|
Modulation of dopamine transporter activity by nicotinic acetylcholine receptors and membrane depolarization in rat pheochromocytoma PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Barium Compounds; Biological Transport; Carrier Proteins; Cell Mem | 1999 |
Release of (3H)norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation.
Topics: Animals; Atropine; Calcium; Clone Cells; Dimethylphenylpiperazinium Iodide; Dose-Response Relationsh | 1977 |
Nicotinic and muscarinic agonists stimulate rapid protein kinase C translocation in PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Carbachol; Cell Membrane; Dimethylphenylpiperazinium Iodi | 1989 |