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dimethylphenylpiperazinium iodide and Pain

dimethylphenylpiperazinium iodide has been researched along with Pain in 5 studies

Dimethylphenylpiperazinium Iodide: A selective nicotinic cholinergic agonist used as a research tool. DMPP activates nicotinic receptors in autonomic ganglia but has little effect at the neuromuscular junction.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
" In the present investigation, we used intrathecal administration of drugs to rats to show that muscarinic or nicotinic agonists such as bethanechol (BCh) and dimethylphenylpiperazinium (DM), respectively, dose-dependently increased the tail flick latency and reduced the pain produced by a surgical incision performed on the plantar aspect of a hind paw."7.72Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats. ( Prado, WA; Segalla, DK, 2004)
" In the present investigation, we used intrathecal administration of drugs to rats to show that muscarinic or nicotinic agonists such as bethanechol (BCh) and dimethylphenylpiperazinium (DM), respectively, dose-dependently increased the tail flick latency and reduced the pain produced by a surgical incision performed on the plantar aspect of a hind paw."3.72Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats. ( Prado, WA; Segalla, DK, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dong, JC1
Wang, X1
Li, RT1
Zhang, HM1
Cheng, TM1
Li, CL1
Prado, WA2
Segalla, DK1
Puttfarcken, PS1
Manelli, AM1
Arneric, SP1
Donnelly-Roberts, DL1
Guimarães, AP1
Guimarães, FS1
Phan, DV1
Dóda, M1
Bite, A1
György, L1

Other Studies

5 other studies available for dimethylphenylpiperazinium iodide and Pain

ArticleYear
Synthesis and analgesic activity of hydrochlorides and quaternary ammoniums of epibatidine incorporated with amino acid ester.
    Bioorganic & medicinal chemistry letters, 2003, Dec-15, Volume: 13, Issue:24

    Topics: Amino Acids; Analgesics, Non-Narcotic; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dose-Respon

2003
Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats.
    Brain research, 2004, Aug-27, Volume: 1018, Issue:2

    Topics: Acetylcholine; Analgesics; Analysis of Variance; Animals; Atropine; Bethanechol; Cholinergic Agonist

2004
Evidence for nicotinic receptors potentially modulating nociceptive transmission at the level of the primary sensory neuron: studies with F11 cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cy

1997
Modulation of carbachol-induced antinociception from the rat periaqueductal gray.
    Brain research bulletin, 2000, Volume: 51, Issue:6

    Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Anxiety; Bethanechol; Carbachol; Cholinergic Agon

2000
Antin ociceptive activity of nicotine.
    Acta physiologica Academiae Scientiarum Hungaricae, 1973, Volume: 44, Issue:1

    Topics: Acetates; Analgesia; Animals; Dimethylphenylpiperazinium Iodide; Drug Tolerance; Injections, Intrape

1973