dimethylnitrosamine has been researched along with Necrosis in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (52.94) | 18.7374 |
| 1990's | 10 (19.61) | 18.2507 |
| 2000's | 10 (19.61) | 29.6817 |
| 2010's | 4 (7.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endo, K; Hori, T; Iwaisako, K; Jobara, K; Kaido, T; Uchida, Y; Uemoto, S | 1 |
| Chen, Y; Duan, X; Gao, Y; Li, J; Xu, Y; Zhang, K; Zhong, M; Zhu, H | 1 |
| Kang, JK; Shin, JW; Son, CG; Wang, JH | 1 |
| Corcoran, GB; Parmar, M; Rathod, J; Ray, SD; Syed, I | 1 |
| Enzan, H; Guo, LM; Hayashi, Y; Hiroi, M; Jin, YL; Kuroda, N; Miyazaki, E; Nakayama, H; Saibara, T; Toi, M; Zhang, YH | 1 |
| Bagchi, D; Bagchi, M; Preuss, HG; Ray, SD; Stohs, SJ | 1 |
| Etani, Y; Kondou, H; Michigami, T; Miyoshi, Y; Mushiake, S; Ozono, K | 1 |
| George, J; Takase, S; Tsutsumi, M | 1 |
| Enzan, H; Guo, LM; Hamauzu, T; Hayashi, Y; Hiroi, M; Jin, YL; Kuroda, N; Miyazaki, E; Saibara, T; Shen, ZS; Toi, M | 1 |
| Enzan, H; Jin, YL; Shi, SH; Tian, C; Zhou, Q | 1 |
| Hideaki, E; Jin, YL; Shi, SH; Zhou, Q | 1 |
| Marsh, WH; Parsa, I; Sutton, AL | 1 |
| Castro, JA; de Fenos, OM; de Ferreyra, EC; Díaz Gómez, MI; Godoy, HM; Marzi, A | 2 |
| Farber, E; Sarma, DS; Ying, TS | 1 |
| Botta, GC; Contini, S; Mazzoni, MP; Pezzarossa, A; Sansoni, P | 1 |
| Harrold, D; Rogers, Q; Schaeffer, M; Stern, J; Strombeck, DR; Wheeldon, E | 1 |
| Boĭm, TM; Rubenchik, BL; Tsapenko, VF | 1 |
| Castro, JA; de Fenos, OM; de Ferreyra, EC | 1 |
| Boatto, R; Carrella, G; De Anna, D; Frassetto, A; Massarelli, G; Menghi, R; Soro, P; Spissu, M; Uzzau, A | 1 |
| Miyakawa, M; Sumi, Y | 1 |
| Castro, JA; Diaz Gomez, MI; Godoy, HM | 1 |
| Butt, KM; Marsh, WH; Parsa, I; Sutton, AL | 1 |
| Armstrong, D; Helgebostad, A; Koppang, N; Rimeslåtten, H | 1 |
| Kaya, K; Li, Y | 1 |
| Arai, M; Fujiwara, K; Hirata, K; Masaki, N; Matsui, A; Mochida, S; Nagoshi, S; Ohno, A; Tomiya, T; Yamaoka, M | 1 |
| Bak, UB; Lee, JH; Rim, HJ | 1 |
| Cattley, RC; Conolly, RB; Kato, M; Popp, JA | 1 |
| Broitman, S; Newberne, PM; Schrager, TF | 1 |
| Fujiwara, K; Ogata, I; Tomiya, T | 1 |
| Inoue, K; Mizuoka, H; Shikata, N; Takasu, M; Tsubura, A; Yang, J | 1 |
| Hasegawa, H; Itoh, J; Nagata, H; Okabe, T; Osamura, RY; Takekoshi, S; Watanabe, K; Yasuda, M | 1 |
| Chandrakasan, G; George, J; Rao, KR; Stern, R | 1 |
| Bagchi, D; Bagchi, M; Raje, RR; Ray, SD; Rinkovsky, A; Wong, V | 1 |
| Chopra, P; Das, PK; Dhar, A; Nayak, NC | 1 |
| Abanobi, SE; Chang, SK; Hadjiolov, D; Harrington, GW; Levitt, M; Lotlikar, PD; Popp, JA; Rajalakshmi, S; Sarma, DS | 1 |
| Matas, AJ; Najarian, JS; Numata, M; Simmons, RL; Sutherland, DE | 1 |
| Columbano, A; Dessi, S; Diaz, G; Ledda, GM; Pani, P; Porcu, M | 1 |
| Chu, C; Mirvish, SS | 1 |
| Burns, JJ; Conney, AH; Dashman, T; Kamm, JJ | 1 |
| Castro, JA; D'Acosta, N; de Castro, CR; de Fenos, OM; de Ferreyra, EC; Díaz Gómez, MI | 1 |
| Golub, NI; Kolesnichenko, TS; Shabad, LM | 1 |
| Lawson, TA; Pound, AW | 1 |
| Rangga-Tabbu, C; Sleight, SD | 1 |
| Elias, R; Nagabhushan, M; Ng, YK; Polverini, PJ; Solt, DB | 1 |
| Brésil, H; Hall, J; Martel-Planche, G; Montesano, R; Serres, M; Wild, CP | 1 |
| Butler, WH; Pritchard, DJ | 1 |
| Fujiwara, K; Ogata, I | 1 |
| Díaz-Gil, JJ; Escartín, P; Esteban, P; Gea, T; Sánchez, G; Santamaría, L; Trilla, C | 1 |
| Berger, ML; Shertzer, HG; Tabor, MW | 1 |
| Landon, EJ; Naukam, RJ; Rama Sastry, BV | 1 |
1 review(s) available for dimethylnitrosamine and Necrosis
| Article | Year |
|---|---|
[Apoptosis in toxicology].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Apoptosis; Cytokines; Dimethylnitrosamine; DNA; fas Receptor; Flow Cytometry; Humans; Necrosis; Polychlorinated Dibenzodioxins; Rats; Signal Transduction | 1994 |
50 other study(ies) available for dimethylnitrosamine and Necrosis
| Article | Year |
|---|---|
Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats.
Topics: Animals; Antioxidants; Cattle; Dimethylnitrosamine; Disease Progression; Glutathione; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirrhosis; Male; Milk Proteins; Necrosis; Peptides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Whey Proteins | 2014 |
Hepatoprotective effects of Dicliptera chinensis polysaccharides on dimethylnitrosamine-induced hepatic fibrosis rats and its underlying mechanism.
Topics: Acanthaceae; Animals; Chemical and Drug Induced Liver Injury; Colchicine; Collagen; Cytokines; Dimethylnitrosamine; Liver; Liver Cirrhosis; Liver Function Tests; Male; Necrosis; Polysaccharides; Protective Agents; Rats; Rats, Sprague-Dawley | 2016 |
Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats.
Topics: Animals; Antioxidants; Body Weight; Coffea; Coffee; Cytokines; Dimethylnitrosamine; Disease Models, Animal; Gene Expression; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis; Macrophages; Male; Malondialdehyde; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type II; Organ Size; Phytotherapy; Plant Extracts; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Seeds | 2010 |
Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury.
Topics: Alanine Transaminase; Animals; Apoptosis; Carcinogens; Dimethylnitrosamine; DNA Fragmentation; Gene Expression; Liver; Male; Malondialdehyde; Matrix Metalloproteinases, Secreted; Mice; Mice, Inbred C3H; Necrosis; Oxidative Stress; Proto-Oncogene Proteins c-mdm2; Thiobarbituric Acid Reactive Substances; Tumor Suppressor Protein p53 | 2012 |
Tissue remodeling following submassive hemorrhagic necrosis in rat livers induced by an intraperitoneal injection of dimethylnitrosamine.
Topics: Actins; Animals; Cell Division; Cell Movement; Desmin; Dimethylnitrosamine; Disease Models, Animal; Hemorrhage; Injections, Intraperitoneal; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Necrosis; Rats; Rats, Wistar | 2003 |
Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Analgesics, Non-Narcotic; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Blood Urea Nitrogen; Cell Cycle; Creatine Kinase; Dimethylnitrosamine; DNA Damage; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Free Radical Scavengers; Grape Seed Extract; Heart Diseases; Humans; In Vitro Techniques; Injections, Intraperitoneal; Keratinocytes; Kidney Diseases; Lipid Peroxidation; Lung Diseases; Mice; Mice, Inbred ICR; Necrosis; Oxidation-Reduction; Plant Extracts; Proanthocyanidins; Spleen; Tobacco, Smokeless; Vasodilator Agents | 2002 |
A blocking peptide for transforming growth factor-beta1 activation prevents hepatic fibrosis in vivo.
Topics: Animals; Atrophy; Dimethylnitrosamine; Disease Progression; DNA-Binding Proteins; Hydroxyproline; Liver; Liver Cirrhosis; Male; Necrosis; Peptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Expression of hyaluronic acid in N-nitrosodimethylamine induced hepatic fibrosis in rats.
Topics: Actins; Animals; Body Weight; Dimethylnitrosamine; Fibrosis; Hyaluronan Receptors; Hyaluronic Acid; Immunohistochemistry; Liver; Male; Muscle, Smooth; N-Methylaspartate; Necrosis; Nitrosamines; Organ Size; Rats; Time Factors | 2004 |
Vascularization in tissue remodeling after rat hepatic necrosis induced by dimethylnitrosamine.
Topics: Animals; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Fluorescent Antibody Technique; Immunohistochemistry; Injections, Intraperitoneal; Liver; Liver Diseases; Male; Necrosis; Neovascularization, Physiologic; Rats; Rats, Wistar | 2006 |
[Silver impregnation and double immunostaining for alpha-smooth muscle actin and ED-1].
Topics: Actins; Animals; Dimethylnitrosamine; Immunohistochemistry; Liver; Male; Necrosis; Rats; Rats, Wistar; Reticulin; Silver Staining | 2007 |
[Morphologic observation and pathogenesis investigation of regenerated sinusoidal endothelial cells in remodelling rat hepatic necrotic tissue].
Topics: Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Endothelial Cells; Liver; Liver Regeneration; Male; Necrosis; Neovascularization, Physiologic; Rats; Rats, Wistar | 2007 |
An in vitro model of human pancreas carcinogenesis: effects of nitroso compounds.
Topics: Adenocarcinoma, Papillary; Adenocarcinoma, Scirrhous; Adolescent; Adult; Amylases; Animals; Carcinogens; Culture Media; Dimethylnitrosamine; Humans; Methylnitrosourea; Mice; Mice, Nude; Middle Aged; Necrosis; Neoplasm Transplantation; Nitrosamines; Nitrosourea Compounds; Organ Culture Techniques; Pancreas; Pancreatic Neoplasms | 1981 |
Enhancement of the dimethylnitrosamine acute effects in rat liver by prior treatment with triton WR-1339.
Topics: Animals; Carbon Dioxide; Dimethylnitrosamine; DNA; Drug Synergism; Liver; Male; Microsomes, Liver; Necrosis; Polyethylene Glycols; Rats; RNA | 1981 |
The sequential analysis of liver cell necrosis: inhibition of diethylnitrosamine- and dimethylnitrosamine-induced acute liver cell death by posttreatment with diethyldithiocarbamate.
Topics: Animals; Carcinogens; Cell Survival; Diethylnitrosamine; Dimethylnitrosamine; Ditiocarb; Dose-Response Relationship, Drug; L-Iditol 2-Dehydrogenase; Liver; Male; Necrosis; Nitrosamines; Rats; Thiocarbamates; Time Factors; Transaminases | 1980 |
Hepatocellular transplantation in rats with toxic induced liver failure: results of iso-, allo- and xenografts.
Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Liver; Liver Diseases; Liver Transplantation; Male; Necrosis; Rats; Rats, Inbred Strains; Spleen; Time Factors; Transplantation Immunology; Transplantation, Heterologous; Transplantation, Homologous; Transplantation, Isogeneic | 1983 |
Plasma amino acid, glucagon, and insulin concentrations in dogs with nitrosamine-induced hepatic disease.
Topics: Amino Acids; Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Dog Diseases; Dogs; Glucagon; Insulin; Liver; Liver Diseases; Necrosis | 1983 |
[Possibility of N-dimethylnitrosamine formation after parenteral administration of amidopyrine and nitrite to rats].
Topics: Aminopyrine; Animals; Ascorbic Acid; Dimethylnitrosamine; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Necrosis; Nitrites; Phenobarbital; Rats | 1984 |
Late preventive effects on dimethylnitrosamine, thioacetamide or galactosamine-induced liver necrosis of the inhibitor of proteases, phenylmethylsulfonyl fluoride.
Topics: Acetamides; Animals; Dimethylnitrosamine; Drug Evaluation, Preclinical; Galactosamine; Liver; Male; Necrosis; Phenylmethylsulfonyl Fluoride; Rats; Rats, Inbred Strains; Sulfones; Thioacetamide; Time Factors | 1983 |
[Hepatocellular regeneration induced with insulin and glucagon after acute necrosis caused by dimethylnitrosamine].
Topics: Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Drug Combinations; Glucagon; Insulin; Liver Regeneration; Necrosis; Rats; Rats, Inbred Strains | 1982 |
Susceptibility of germ-free rats to the hepatotoxic effects of dimethylnitrosamine or dimethylamine plus sodium nitrite administered orally.
Topics: Administration, Oral; Animals; Dimethylamines; Dimethylnitrosamine; Germ-Free Life; Liver; Male; Necrosis; Nitrites; Rats; Rats, Inbred Strains; Sodium Nitrite | 1983 |
Relationship between dimethylnitrosamine metabolism or activation and its ability to induce liver necrosis in rats.
Topics: Animals; Biotransformation; Chlorpromazine; Cystamine; Dimethylnitrosamine; Diphenhydramine; In Vitro Techniques; Liver; Male; Necrosis; Pyrazoles; Pyridines; Rats | 1980 |
Chicken resistance to dimethylnitrosamine acute effects on the liver: a comparative study with other species.
Topics: Animals; Chickens; Dimethylnitrosamine; Formaldehyde; Guinea Pigs; Isocitrate Dehydrogenase; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Necrosis; Nucleic Acids; Proteins; Rats; Rats, Inbred Strains; Species Specificity; Subcellular Fractions; Time Factors | 1982 |
Effects of dimethylnitrosamine on organ-cultured adult human pancreas.
Topics: Animals; Carcinoma; Dimethylnitrosamine; Epithelium; Humans; Hyperplasia; Mice; Mice, Nude; Necrosis; Neoplasms, Experimental; Organ Culture Techniques; Pancreas; Pancreas Transplantation; Pancreatic Ducts; Pancreatic Neoplasms | 1981 |
Toxic and carcinogenic effects of dimethylnitrosamine (DMNA) in the blue fox (Alopex lagopus).
Topics: Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Female; Foxes; Hemangiosarcoma; Liver; Liver Diseases; Liver Neoplasms; Male; Necrosis; Neoplasms, Experimental | 1981 |
Use of prostaglandin I2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition.
Topics: Animals; Antithrombin III; Capillaries; Carbon Tetrachloride; Cells, Cultured; Dimethylnitrosamine; Endothelium, Vascular; Endotoxins; Epoprostenol; Fibrin; Liver; Liver Diseases; Male; Necrosis; Peptide Hydrolases; Portal Pressure; Propionibacterium acnes; Prothrombin Time; Rats; Rats, Inbred F344 | 1995 |
Effect of Clonorchis sinensis infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian golden hamsters.
Topics: Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Bile Ducts; Clonorchiasis; Cocarcinogenesis; Cricetinae; Dimethylnitrosamine; Fibrosis; Hyperplasia; Liver; Liver Neoplasms; Mesocricetus; Necrosis | 1993 |
Relationship between hepatocyte necrosis, proliferation, and initiation induced by diethylnitrosamine in the male F344 rat.
Topics: Animals; Body Weight; Bromodeoxyuridine; Cell Division; Dimethylnitrosamine; Glutathione Transferase; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Necrosis; Organ Size; Placenta; Rats; Rats, Inbred F344 | 1993 |
Esophageal carcinogenesis in the rat: zinc deficiency, DNA methylation and alkyltransferase activity.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Disease Models, Animal; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Esophagus; Male; Necrosis; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Rats; Rats, Sprague-Dawley; Zinc | 1997 |
Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Cell Division; Dimethylnitrosamine; Disease Models, Animal; Hepatocyte Growth Factor; Liver; Liver Regeneration; Male; Mitotic Index; Necrosis; Phenobarbital; Rats; Rats, Sprague-Dawley; Transforming Growth Factor alpha | 1998 |
Biphasic effect of colchicine on acute liver injury induced by carbon tetrachloride or by dimethylnitrosamine in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; bcl-X Protein; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Colchicine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Proto-Oncogene Proteins c-bcl-2 | 1999 |
Differentiation of necrotic cell death with or without lysosomal activation: application of acute liver injury models induced by carbon tetrachloride (CCL4) and dimethylnitrosamine (DMN).
Topics: Acid Phosphatase; Acute Disease; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; In Situ Nick-End Labeling; Lysosomes; Male; Microscopy, Confocal; Microscopy, Electron; Necrosis; Rats; Rats, Wistar | 2000 |
Dimethylnitrosamine-induced liver injury in rats: the early deposition of collagen.
Topics: Animals; Apoptosis; Behavior, Animal; Body Weight; Collagen; Dimethylnitrosamine; DNA; Eating; Hemorrhage; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Organ Size; Proteins; Rats; Rats, Wistar; Survival Rate | 2001 |
Unique organoprotective properties of a novel IH636 grape seed proanthocyanidin extract on cadmium chloride-induced nephrotoxicity, dimethylnitrosamine (DMN)-induced splenotoxicity and mocap-induced neurotoxicity in mice.
Topics: Activins; Administration, Oral; Alanine Transaminase; Animals; Apoptosis; Biological Availability; Cadmium Chloride; Creatine Kinase; Dimethylnitrosamine; DNA Fragmentation; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Grape Seed Extract; Injections, Intraperitoneal; Kidney Diseases; Male; Mice; Mice, Inbred ICR; Necrosis; Nervous System Diseases; Organothiophosphates; Plant Extracts; Proanthocyanidins; Spleen | 2000 |
Diverse mechanisms of hepatocellular injuries due to chemicals: evidence in rats administered carbon tetrachloride or dimethylnitrosamine.
Topics: Age Factors; Animals; Animals, Newborn; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Fetus; Glucose-6-Phosphatase; Hepatectomy; Liver; Liver Diseases; Necrosis; Nitrosamines; Phenobarbital; Rats; Triglycerides | 1975 |
Inhibition of dimethylnitrosamine-induced strand breaks in liver DNA and liver cell necrosis by diethyldithiocarbamate.
Topics: Aminoacetonitrile; Animals; Cytochromes; Dimethylnitrosamine; Ditiocarb; DNA; DNA Repair; In Vitro Techniques; Liver; Male; Metabolic Clearance Rate; Methylation; Microsomes, Liver; Necrosis; Nitrosamines; Rats; Thiocarbamates; Time Factors | 1977 |
Hepatocellular transplantation in acute liver failure.
Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Liver; Liver Regeneration; Liver Transplantation; Male; Necrosis; Rats; Transplantation, Homologous | 1977 |
Effect of choline administration on the toxicity of N-nitrosodimethylamine in female rats.
Topics: Alanine Transaminase; Animals; Choline; Dimethylnitrosamine; Female; Liver; Necrosis; Nitrosamines; Rats | 1977 |
Effects of nine N-nitroso compounds on the specific radioactivity of liver proteins after injection of [14C]leucine into rats.
Topics: Animals; Cycloleucine; Diethylnitrosamine; Dimethylnitrosamine; Leucine; Liver; Liver Neoplasms; Male; Methylnitrosourea; Morpholines; Necrosis; Nitroso Compounds; Piperazines; Piperidines; Proteins; Rats; Sarcosine; Time Factors | 1977 |
Effect of ascorbic acid on amine-nitrite toxicity.
Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Liver; Liver Diseases; Necrosis; Nitrites; Nitrosamines; Rats | 1975 |
Mechanism of dimethylnitrosamine and carbon tetrachloride-induced liver necrosis: similarities and differences.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dimethylnitrosamine; Isocitrate Dehydrogenase; Lipid Metabolism; Male; Microsomes, Liver; Necrosis; Nitrosamines; Proteins; Rats | 1975 |
The effect produced by some carcinogenic nitrosocompounds on organ cultures from human embryonic lung and kidney tissues.
Topics: Azo Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Epithelial Cells; Epithelium; Humans; Hyperplasia; Kidney; Lung; Methylnitrosourea; Necrosis; Nitrosamines; Nitrosourea Compounds; o-Aminoazotoluene; Organ Culture Techniques; Time Factors | 1975 |
Protection by carbon tetrachloride against the toxic effects of dimethylnitrosamine in mice.
Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Lethal Dose 50; Liver; Male; Mice; Microsomes, Liver; Necrosis; Nitrosamines; Oxidoreductases, N-Demethylating; Time Factors | 1975 |
Sequential study in rats of nasal and hepatic lesions induced by N-nitrosodimethylamine and N-nitrosopyrrolidine.
Topics: Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Drug Synergism; Female; Liver; N-Nitrosopyrrolidine; Nasal Mucosa; Necrosis; Nose Diseases; Rats; Rats, Sprague-Dawley | 1992 |
Acute inhibition of DNA synthesis in hamster buccal pouch epithelium exposed to indirect acting carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Cell Division; Cricetinae; Dimethylnitrosamine; DNA; Male; Mesocricetus; Methylcholanthrene; Mouth Mucosa; Necrosis; Time Factors | 1990 |
Modulation of O6-methylguanine-DNA methyltransferase in rat and hamster liver after treatment with dimethylnitrosamine.
Topics: Animals; Cricetinae; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Kinetics; Liver; Male; Mesocricetus; Methyltransferases; Necrosis; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains; Thymidine | 1990 |
Apoptosis--the mechanism of cell death in dimethylnitrosamine-induced hepatotoxicity.
Topics: Animals; Cell Survival; Dimethylnitrosamine; Lectins; Liver; Male; Microscopy, Electron; Necrosis; Rats | 1989 |
Collagen accumulation can continue with decreased prolyl hydroxylase activity in the liver.
Topics: Alanine Transaminase; Animals; Collagen; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hydroxyproline; Liver; Male; Necrosis; Procollagen-Proline Dioxygenase; Rats; Rats, Inbred Strains | 1985 |
A liver DNA synthesis promoter induced in rat plasma by injection of dimethylnitrosamine (DMNA) or thioacetamide.
Topics: Acetamides; Animals; Dimethylnitrosamine; DNA; Liver; Liver Regeneration; Necrosis; Rats; Rats, Inbred Strains; Thioacetamide; Transaminases | 1987 |
Protection from N-nitrosodimethylamine-mediated liver damage by indole-3-carbinol.
Topics: Alanine Transaminase; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Indoles; Liver Diseases; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Necrosis; Ornithine Carbamoyltransferase; Oxidoreductases, N-Demethylating | 1987 |
Effects of calcium channel blocking agents on calcium and centrilobular necrosis in the liver of rats treated with hepatotoxic agents.
Topics: Acetaminophen; Animals; Calcium; Calcium Channel Blockers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Dimethylnitrosamine; Liver; Male; Microsomes, Liver; Necrosis; Rats; Rats, Inbred Strains; Thioacetamide | 1986 |