Page last updated: 2024-08-17

dimethylnitrosamine and Liver Neoplasms

dimethylnitrosamine has been researched along with Liver Neoplasms in 125 studies

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-199091 (72.80)18.7374
1990's15 (12.00)18.2507
2000's7 (5.60)29.6817
2010's9 (7.20)24.3611
2020's3 (2.40)2.80

Authors

AuthorsStudies
Boonmars, T; Boonnate, P; Fujikawa, S; Kariya, R; Okada, S; Pairojkul, C; Pinlaor, S; Vaeteewoottacharn, K1
Aoyama, Y; Inaguma, S; Kato, H; Komura, M; Matsuo, Y; Nagayasu, Y; Naiki-Ito, A; Takahashi, S; Takiguchi, S; Tomita, M; Tsuda, H; Xiaochen, K1
Botton, J; Haddy, N; Mansouri, I; Semenzato, L; Zureik, M1
Chamgramol, Y; Hongsrichan, N; Khuntikeo, N; Pairojkul, C; Pinlaor, P; Pinlaor, S; Rucksaken, R; Techasen, A; Yongvanit, P1
Boonsiri, P; Charoensuk, L; Intuyod, K; Johns, NP; Laothong, U; Pairojkul, C; Pinlaor, P; Pinlaor, S; Priprem, A1
Ho, CT; Lai, CS; Lee, YL; Li, S; Pan, MH; Tsai, CY; Wan, X; Weerawatanakorn, M1
Cerven, DR; de George, G; Iatropoulos, MJ; von Keutz, E; Williams, GM1
Bako, F; Banfalvi, G; Hunyadi, J; Juhasz, T; Kertai, P; Marian, T; Pocsi, I; Trencsenyi, G1
Baydar, T; Erkekoglu, P1
Dumont, J; Fessard, V; Guguen-Guillouzo, C; Guillouzo, A; Huet, S; Josse, R; Lanceleur, R; Le Hegarat, L; Mourot, A; Poul, JM1
DeAngelo, AB; George, MH; Hobbie, KR; Law, JM1
Becker, K; Boger, RJ; Ehrenberg, KR; Hahn, M; Hövelmeyer, N; Jäger, D; Longerich, T; Schuchmann, M; Schulze-Bergkamen, H; Urbanik, T; Waisman, A; Wörns, MA1
Aukkanimart, R; Boonmars, T; Juasook, A; Loilome, W; Namwat, N; Sriraj, P; Sudsarn, P; Veteewuthacharn, K; Wonkchalee, O; Wu, Z1
Chagnon, MC; Le Bon, AM; Le Hegarat, L; Lhuguenot, JC; Valentin-Severin, I1
Bader, A; Stahl, F; Wilkening, S1
BARNES, JM; MAGEE, PN1
BROUWERS, JA; EMMELOT, P2
AFZELIUS, BA; ARRHENIUS, E; GUSTAFSSON, RG; MUKHERJEE, T1
OOTA, K; TAKAYAMA, S2
MAGEE, PN; TERRACINI, B1
MAGEE, PN; SHUBIK, P; TOMATIS, L1
MAGEE, PN; SHUBIK, P; TOTH, B1
Devi, BJ; Schneeweiss, FH; Sharan, RN1
Bagchi, D; Parikh, H; Ray, SD1
Banfalvi, G; Dombradi, Z; Gacsi, M; Kertai, P; Nagy, G; Somogyi, C; Trencsényi, G1
Bhothisuwan, K; Brunnemann, KD; Caplan, LS; Gagna, CE; Hummel, CF; Martin, N; Mitacek, EJ; Ohshima, H; Roy, R; Siriamornpun, S; Suttajit, M1
Gorban', GP; Osipova, LA; Pliss, MB; Zakharenko, LN1
Archer, MC; Labuc, GE1
Ohmori, T; Tabei, R1
Pegg, AE2
Khudoley, VV; Picard, JJ1
Emmelot, P; Scherer, E1
Tannenbaum, SR1
Huh, N; Nemoto, N; Utakoji, T1
Digernes, V; Elgjo, K1
Anderson, LM; Budinger, JM; van Havere, K1
Arai, M; Hibino, T; Hirasawa, Y; Ouchi, N; Takino, H1
Moskadynova, GA; Osipenko, BG; Portianaia, NI1
Buchmann, A; Kunz, W; Moore, M; Schwarz, M1
Lijinsky, W; Reuber, MD1
Digernes, V1
Frenzel, H; Minzlaff, M; Oldiges, H; Teschke, R1
Farber, E1
Goodall, CM; Noronha, RF2
Lijinsky, W1
Ockey, CH; Swindell, JA1
Lijinsky, W; Reuber, MD; Saavedra, JE; Singer, SS1
Arcos, JC; Lai, DY1
Driver, HE; McLean, AE; Smith, M1
Arai, M; Fukushima, S; Ito, N; Shirai, T; Tsuda, H1
Armstrong, D; Helgebostad, A; Koppang, N; Rimeslåtten, H1
Montesano, R1
Chu, JJ; Xu, YC; Ye, BF1
Ito, N; Pairojkul, C; Shirai, T; Thamavit, W; Tiwawech, D1
Asamoto, M; Iwase, T; Kato, T; Matsumoto, K; Montesano, R; Nagao, S; Ozaki, K; Tsuda, H; Wild, CP1
Ishikawa, T; Matsukuma, S; Nakatsuru, Y; Nemoto, N; Sekiguchi, M; Sugano, H1
Bak, UB; Lee, JH; Rim, HJ1
Clawson, GA; Crone, TM; Miranda, GQ; Schalles, SL; Weisz, J; Wolz, G1
Carthew, P; Edwards, RE; Nolan, BM1
Igarashi, H; Ishikawa, T; Iwakuma, T; Kawate, H; Nakatsuru, Y; Sakumi, K; Sekiguchi, M; Shiraishi, A; Tsuzuki, T1
Gu, J1
Helma, C; Knasmüller, S; Uhl, M1
LaBar, J; Sander, J1
Nizami, F; Nizami, HM1
Diehl, B; Habs, M; Krüger, FW; Schmähl, D1
Becker, FF2
Craddock, VM1
Bills, DD; Nixon, JE; Scanlan, RA; Sinnhuber, RO; Wales, JH1
Matsushima, T; Sugimura, T1
Dybing, E1
Khudoley, VV1
Eltze, M; Jackisch, R; Jung, A1
Avertsev, SA; Fel', VIa; Ivanov, VA; Olenov, IuM1
Betz, EH; Fridman-Manduzio, A; Gol-Winkler, R; Goutier, R1
Grieco, MP; Hendricks, JD; Pierce, DA; Scanlan, RA; Sinnhuber, RO1
Arcos, JC; Argus, MF; Conney, AH; Hoch-Ligeti, C1
Enomoto, K; Ogawa, K; Onoé, T; Yoshida, Y1
Aikawa, T; Kera, K; Terao, K1
Bannasch, P; Mattern, J; Volm, M; Wayss, K2
Katahira, S; Konno, K; Minami, K; Yokota, T1
Chopra, P; Manga, A; Nayak, NC1
Hirono, I; Uchida, E1
Abanobi, SE; Farber, E; Sarma, DS1
Green, U; Ketkar, MB; Mohr, U; Richter-Reichhelm, HB1
Brown, CC1
Chu, C; Mirvish, SS1
Garcia, H; Love, LA; Pelfrene, A1
Cameron, R; Farber, E; Laishes, B; Medline, A; Ogawa, K; Solt, D1
Egami, N; Kyono, Y1
Farber, E; Gruenstein, M; Parker, S1
Margison, GP; Margison, JM; Montesano, R1
Koppang, N; Rimeslåtten, H1
Farber, E; Klaiber, M; Parker, SE; Williams, GM1
Read, J1
Mondal, S1
Benemanskiĭ, VV; Moiseev, GE1
Lawson, TA; Pound, AW1
Reznik, G1
Kmoch, N; Mohr, U; Reznik, G1
Aufderheide, M; Kohler, M; Mohr, U; Steinmann, J1
Anderson, LM; Carter, JP; Driver, CL; Kovatch, RM; Logsdon, DL1
Armato, U; Carcereri dePrati, A; Menapace, L; Menegazzi, M; Miwa, M; Ribecco, M; Suzuki, H; Testolin, L1
Kanduc, D; Quagliariello, E1
Ahotupa, M; Bartsch, H; Bereziat, JC; Cabral, JR; Camus, AM; Hietanen, E; Laitinen, M1
Roscher, E; Wiebel, FJ1
Dolan, M; Fausto, N; Goyette, M; Kaufman, D; Kaufmann, W; Shank, PR1
Diwan, BA; Ohshima, M; Rice, JM1
Anderson, LM; Fox, SD; Isaaq, HJ; Riggs, CW; Ward, JM1
Hacobian, N; Ho, LL; Lotlikar, PD; Magee, PN; Prasanna, HR1
Bruschelli, G; Guerrieri, P; Liotti, FS; Locci, P; Mariucci, G; Menghini, AR1
Klein, RG; Komitowski, D; Pool, BL; Schmähl, D; Schmezer, P1
Castro, JA; Diaz Gomez, MI; Lopez, AJ; Martino, PE; Tamayo, D1
Mandel, R; Ryser, HJ; Wade, GG1
Kovatch, RM; Kroeger-Koepke, MB; Michejda, CJ1
Kaufmann, WK; Novicki, DL; Tsao, MS1
Castonguay, A; Hecht, SS; Rivenson, A; Trushin, N1
Kaufman, DG; Kaufmann, WK; MacKenzie, SA1
Likhachev, A; Montesano, R; Planche-Martel, G; Wild, CP1
Abraham, R; Charles, AK; Timchalk, C1

Reviews

5 review(s) available for dimethylnitrosamine and Liver Neoplasms

ArticleYear
Metabolism of N-nitrosodimethylamine.
    IARC scientific publications, 1980, Issue:27

    Topics: Animals; Biotransformation; Carcinogens; Dimethylnitrosamine; DNA; Humans; Intestinal Absorption; Kidney; Kidney Neoplasms; Kinetics; Liver; Liver Neoplasms; Methylation; Methyltransferases; Oxygen Consumption; RNA

1980
The first relevant cell stage in rat liver carcinogenesis. A quantitative approach.
    Biochimica et biophysica acta, 1980, May-06, Volume: 605, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Basophils; Carcinoma, Hepatocellular; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hepatectomy; Histocytochemistry; Immunogenetics; Kinetics; Liver; Liver Glycogen; Liver Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors

1980
Minireview: dialkylnitrosamine bioactivation and carcinogenesis.
    Life sciences, 1980, Dec-08, Volume: 27, Issue:23

    Topics: Alkylation; Animals; Biotransformation; Chemical Phenomena; Chemistry; Diethylnitrosamine; Dimethylnitrosamine; DNA; Kinetics; Liver Neoplasms; Nitrosamines; Oxidoreductases; Oxidoreductases, N-Demethylating

1980
Progress of cancer research in China.
    Chinese medical journal, 1997, Volume: 110, Issue:1

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Esophageal Neoplasms; Herpesvirus 4, Human; Humans; Liver Neoplasms; Nasopharyngeal Neoplasms

1997
Experimental carcinogenesis in small aquarium fishes.
    Progress in experimental tumor research, 1976, Volume: 20

    Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Cycasin; Diethylnitrosamine; Dimethylnitrosamine; Female; Fishes; Goldfish; Liver Neoplasms; Male; Methylcholanthrene; Neoplasms, Experimental; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Sterigmatocystin; Trout

1976

Other Studies

120 other study(ies) available for dimethylnitrosamine and Liver Neoplasms

ArticleYear
Mucin-producing hamster cholangiocarcinoma cell line, Ham-2, possesses the aggressive cancer phenotypes with liver and lung metastases.
    In vitro cellular & developmental biology. Animal, 2021, Volume: 57, Issue:8

    Topics: Animals; Bile Duct Neoplasms; Carcinogens; Cell Line, Tumor; Cholangiocarcinoma; Cricetinae; Dimethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Mucins; Neoplasm Transplantation; Opisthorchiasis; Opisthorchis

2021
Lactoferrin Prevents Hepatic Injury and Fibrosis via the Inhibition of NF-κB Signaling in a Rat Non-Alcoholic Steatohepatitis Model.
    Nutrients, 2021, Dec-23, Volume: 14, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Carcinoma, Hepatocellular; Connexins; Cytokines; Dimethylnitrosamine; Fibrosis; Gap Junction beta-1 Protein; Lactoferrin; Liver; Liver Cirrhosis; Liver Neoplasms; Male; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2021
    Journal of the American Heart Association, 2022, 12-20, Volume: 11, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Dimethylnitrosamine; Drug Contamination; Humans; Liver Neoplasms; Melanoma; Middle Aged; Valsartan

2022
Annexin A1: A new immunohistological marker of cholangiocarcinoma.
    World journal of gastroenterology, 2013, Apr-28, Volume: 19, Issue:16

    Topics: Animals; Annexin A1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biomarkers, Tumor; Biopsy; Carcinoma, Hepatocellular; Case-Control Studies; Cell Line, Tumor; Cholangiocarcinoma; Cricetinae; Dimethylnitrosamine; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Liver Neoplasms; Male; Mesocricetus; Middle Aged; Opisthorchis; RNA Interference; RNA, Messenger; Tissue Array Analysis; Transfection

2013
Melatonin inhibits cholangiocarcinoma and reduces liver injury in Opisthorchis viverrini-infected and N-nitrosodimethylamine-treated hamsters.
    Journal of pineal research, 2013, Volume: 55, Issue:3

    Topics: Animals; Antioxidants; Cholangiocarcinoma; Cricetinae; Dimethylnitrosamine; DNA Fragmentation; DNA, Neoplasm; Humans; Liver; Liver Neoplasms; Male; Melatonin; Mesocricetus; Mitochondria, Liver; Neoplasm Proteins; Opisthorchiasis; Opisthorchis; Time Factors

2013
Protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats.
    Food & function, 2015, Volume: 6, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Bile Ducts, Intrahepatic; Biomarkers; Camellia sinensis; Carcinogens; Carcinoma, Hepatocellular; Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Dimethylnitrosamine; Food Handling; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Male; Oxidation-Reduction; Plant Extracts; Plant Leaves; Protective Agents; Random Allocation; Rats, Sprague-Dawley

2015
Reduction by dietary matrix metalloproteinase inhibitor BAY 12-9566N of neoplastic development induced by diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in rats.
    Drug and chemical toxicology, 2008, Volume: 31, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Biphenyl Compounds; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Drug Screening Assays, Antitumor; Female; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Matrix Metalloproteinase Inhibitors; Neoplasms; Organic Chemicals; Phenylbutyrates; Rats; Rats, Wistar; Sex Factors

2008
Comparison of the tumorigenic potential of liver and kidney tumors induced by N-nitrosodimethylamine.
    Histology and histopathology, 2010, Volume: 25, Issue:3

    Topics: Analysis of Variance; Animals; Autoradiography; Biomarkers, Tumor; Blotting, Western; Carcinogenicity Tests; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Dimethylnitrosamine; Flow Cytometry; Fluorodeoxyglucose F18; Glucose Transporter Type 1; Glucose Transporter Type 3; Immunohistochemistry; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Mesenchymoma; Microscopy, Fluorescence; Radionuclide Imaging; Rats; Transforming Growth Factor beta1

2010
Evaluation of the protective effect of ascorbic acid on nitrite- and nitrosamine-induced cytotoxicity and genotoxicity in human hepatoma line.
    Toxicology mechanisms and methods, 2010, Volume: 20, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Survival; Comet Assay; Cytoprotection; Diethylnitrosamine; Dimethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Liver Neoplasms; Mutagens; Nitrites; Nitrosamines; Oxidative Stress; Reactive Oxygen Species; Time Factors

2010
Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.
    Mutagenesis, 2010, Volume: 25, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; Cytokinesis; Dimethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Micronucleus Tests; Mutagens; Rats

2010
Neoplastic and nonneoplastic liver lesions induced by dimethylnitrosamine in Japanese medaka fish.
    Veterinary pathology, 2012, Volume: 49, Issue:2

    Topics: Animals; Animals, Genetically Modified; Biliary Tract Neoplasms; Biomarkers; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fish Diseases; Liver; Liver Neoplasms; Male; Mutagenicity Tests; Oryzias; Rats; Signal Transduction; Species Specificity; Transforming Growth Factor beta

2012
Liver specific deletion of CYLDexon7/8 induces severe biliary damage, fibrosis and increases hepatocarcinogenesis in mice.
    Journal of hepatology, 2012, Volume: 57, Issue:5

    Topics: Animals; Biliary Tract Diseases; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Dimethylnitrosamine; Disease Models, Animal; Exons; Fibrosis; Gene Deletion; Genetic Predisposition to Disease; Homeostasis; In Vitro Techniques; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenobarbital; Phenotype; Risk Factors

2012
Immunosuppressive prednisolone enhances early cholangiocarcinoma in Syrian hamsters with liver fluke infection and administration of N-nitrosodimethylamine.
    Pathology oncology research : POR, 2013, Volume: 19, Issue:1

    Topics: Animals; Bile Duct Neoplasms; Cell Transformation, Neoplastic; Cholangiocarcinoma; Chronic Disease; Cocarcinogenesis; Cricetinae; Cyclooxygenase 2; Dimethylnitrosamine; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Liver; Liver Cirrhosis; Liver Neoplasms; Mesocricetus; Opisthorchiasis; Prednisolone

2013
Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.
    Mutation research, 2003, Apr-20, Volume: 536, Issue:1-2

    Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Carcinoma, Hepatocellular; Comet Assay; Dimethylnitrosamine; Humans; Inhibitory Concentration 50; Liver Neoplasms; Methyl Methanesulfonate; Micronucleus Tests; Mutagens; Nitrosamines; Quinolones; Sensitivity and Specificity; Tumor Cells, Cultured

2003
Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:8

    Topics: 7-Alkoxycoumarin O-Dealkylase; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; Cytochrome P-450 CYP1A1; Cytoskeleton; Dimethylnitrosamine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression; Hepatocytes; Humans; Imidazoles; Inactivation, Metabolic; Liver Neoplasms; Male; Middle Aged; Mutagens; Reverse Transcriptase Polymerase Chain Reaction

2003
The production of malignant primary hepatic tumours in the rat by feeding dimethylnitrosamine.
    British journal of cancer, 1956, Volume: 10, Issue:1

    Topics: Amines; Animals; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Rats

1956
[The effect of the hepatic carcinogen dimethylnitrosamine on protein synthesis in liver and hepatoma].
    Jaarboek : verslagen en mededelingen der Koninklijke Nederlandse Botanische Vereniging over het jaar ... Koninklijke Nederlandse Botanische Vereniging, 1959, Volume: 9

    Topics: Amines; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Liver; Liver Neoplasms; Protein Biosynthesis; Proteins

1959
Microsomal N-demethylation and the effect of the hepatic carcinogen dimethylnitrosamine on amino acid incorporation into the proteins of rat livers and hepatomas.
    Experimental cell research, 1960, Volume: 19

    Topics: Amino Acids; Animals; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Liver Neoplasms; Liver Neoplasms, Experimental; Proteins; Rats

1960
EFFECTS OF CARCINOGENIC AMINES ON AMINO ACID INCORPORATION BY LIVER SYSTEMS. II. A MORPHOLOGICAL AND BIOCHEMICAL STUDY ON THE EFFECT OF DIMETHYLNITROSAMINE.
    Cancer research, 1963, Volume: 23

    Topics: Amines; Amino Acids; Carbon Isotopes; Carcinogens; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Electrons; Hepatitis; Leucine; Liver; Liver Glycogen; Liver Neoplasms; Microscopy; Microscopy, Electron; Mitochondria; Nitrosamines; Proteins; Rats; Research; Toxicology

1963
MALIGNANT TUMORS INDUCED IN MICE FED WITH N-NITROSODIMETHYLAMINE.
    Gan, 1963, Volume: 54

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Dimethylnitrosamine; Hemangioendothelioma; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms, Experimental; Nitrosamines; Pathology; Research; Splenic Neoplasms

1963
RENAL TUMOURS IN RATS FOLLOWING INJECTION OF DIMETHYLNITROSAMINE AT BIRTH.
    Nature, 1964, May-02, Volume: 202

    Topics: Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Lymphoma; Neoplasms; Neoplasms, Experimental; Nitrosamines; Pharmacology; Rats; Research

1964
INDUCTION OF LIVER TUMORS IN THE SYRIAN GOLDEN HAMSTER BY FEEDING DIMETHYLNITROSAMINE.
    Journal of the National Cancer Institute, 1964, Volume: 33

    Topics: Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Cricetinae; Dimethylnitrosamine; Hemangioendothelioma; Kidney Neoplasms; Liver Neoplasms; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pathology; Research; Toxicology

1964
CARCINOGENESIS STUDY WITH DIMETHYLNITROSAMINE ADMINISTERED ORALLY TO ADULT AND SUBCUTANEOUSLY TO NEWBORN BALB-C MICE.
    Cancer research, 1964, Volume: 24

    Topics: Adenoma; Aging; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Hemangioma; Hemangiosarcoma; Humans; Injections, Subcutaneous; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrosamines; Pathology; Research; Sertoli Cell Tumor

1964
INDUCTION OF MALIGNANT TUMORS IN VARIOUS STRAINS OF MICE BY ORAL ADMINISTRATION OF N-NITROSODIMETHYLAMINE AND N-NITROSODIETHYLAMINE.
    Gan, 1965, Volume: 56

    Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Dysgerminoma; Female; Hemangiosarcoma; Humans; Kidney Neoplasms; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Mice; Nitroso Compounds; Ovarian Neoplasms; Papilloma; Pathology; Research; Skin Neoplasms; Stomach Neoplasms; Testicular Neoplasms

1965
Negative correlation between poly-ADP-ribosylation of spleen cell histone proteins and initial duration of dimethylnitrosamine exposure to mice in vivo measured by Western blot immunoprobe assay: a possible biomarker for cancer detection.
    Cancer detection and prevention, 2005, Volume: 29, Issue:1

    Topics: Animals; Biomarkers, Tumor; Blotting, Western; Cell Transformation, Neoplastic; Dimethylnitrosamine; Histones; Immunoassay; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Poly Adenosine Diphosphate Ribose; Proteins; Sensitivity and Specificity; Spleen

2005
Proanthocyanidin exposure to B6C3F1 mice significantly attenuates dimethylnitrosamine-induced liver tumor induction and mortality by differentially modulating programmed and unprogrammed cell deaths.
    Mutation research, 2005, Nov-11, Volume: 579, Issue:1-2

    Topics: Animals; Antioxidants; Apoptosis; Cell Death; Creatine Kinase; Dimethylnitrosamine; Glutathione; Kidney; Lipid Peroxides; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Plant Extracts; Proanthocyanidins; Superoxide Dismutase

2005
Chemically induced carcinogenesis affecting chromatin structure in rat hepatocarcinoma cells.
    DNA and cell biology, 2007, Volume: 26, Issue:9

    Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transformation, Neoplastic; Chromatin; Dimethylnitrosamine; Hepatocytes; Liver Neoplasms; Male; Nitrosamines; Rats; Rats, Inbred F344; Rats, Long-Evans; Tumor Cells, Cultured

2007
Geographic distribution of liver and stomach cancers in Thailand in relation to estimated dietary intake of nitrate, nitrite, and nitrosodimethylamine.
    Nutrition and cancer, 2008, Volume: 60, Issue:2

    Topics: Adult; Carcinogens; Demography; Diet; Diet Surveys; Dimethylnitrosamine; Female; Food Analysis; Food Handling; Humans; Incidence; Liver Neoplasms; Male; Meat; Middle Aged; Nitrates; Nitrites; Stomach Neoplasms; Surveys and Questionnaires; Thailand

2008
[Biochemical characteristics of major fractions of rat liver cells in dimethylnitrosamine-induced carcinogenesis].
    Voprosy onkologii, 1984, Volume: 30, Issue:11

    Topics: Animals; Dimethylnitrosamine; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Hexokinase; Liver; Liver Glycogen; Liver Neoplasms; Male; Rats; Time Factors

1984
Comparative tumor initiating activities of N-nitrosomethylbenzylamine and N-nitrosodimethylamine in rat liver.
    Carcinogenesis, 1982, Volume: 3, Issue:5

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA; gamma-Glutamyltransferase; Hepatectomy; Injections, Intraperitoneal; Liver Neoplasms; Male; Microsomes, Liver; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred Strains

1982
Modulation of N-nitrosodimethylamine kidney tumorigenesis by unilateral hydronephrosis and multiple putrescine administrations.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:4

    Topics: Animals; Body Weight; Dimethylnitrosamine; Female; gamma-Glutamyltransferase; Hydronephrosis; Kidney; Kidney Neoplasms; Liver Neoplasms; Nephrectomy; Organ Size; Putrescine; Rats; Rats, Inbred Strains; Trypan Blue

1983
Liver and kidney tumors induced by N-nitroso-dimethylamine in Xenopus borealis (Parker).
    International journal of cancer, 1980, May-15, Volume: 25, Issue:5

    Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma; Carcinoma, Hepatocellular; Dimethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Neoplasms, Experimental; Xenopus

1980
A model for estimation of human exposure to endogenous N-nitrosodimethylamine.
    Oncology, 1980, Volume: 37, Issue:4

    Topics: Carcinoma, Hepatocellular; Dimethylnitrosamine; Dose-Response Relationship, Drug; Environmental Exposure; Liver Neoplasms; Mathematics; Models, Biological; Risk

1980
Metabolic activation of benzo[a]pyrene, aflatoxin B1, and dimethylnitrosamine by a human hepatoma cell line.
    Mutation research, 1982, Volume: 94, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Dimethylnitrosamine; Humans; Liver Neoplasms; Middle Aged; Sister Chromatid Exchange

1982
Dimethyl nitrosamine-induced proliferative and neoplastic lesions in the mouse liver characterized by histopathology and flow cytometric DNA measurements.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, 1984, Volume: 92, Issue:1

    Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; DNA, Neoplasm; Female; Flow Cytometry; Histocytochemistry; Liver Neoplasms; Male; Mice; Neoplasms, Experimental; Ploidies

1984
Effects of polychlorinated biphenyls on lung and liver tumors initiated in suckling mice by N-nitrosodimethylamine.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:1

    Topics: Age Factors; Animals; Animals, Suckling; Cocarcinogenesis; Dimethylnitrosamine; Drug Interactions; Female; Gestational Age; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Polychlorinated Biphenyls; Pregnancy; Time Factors

1983
Comparative enhancing effects of polychlorinated biphenyls and phenobarbital on dimethylnitrosamine-induced hepatic and renal tumorigenesis in rats.
    Developments in toxicology and environmental science, 1983, Volume: 11

    Topics: Animals; Dimethylnitrosamine; Drug Synergism; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Male; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344

1983
[Phospholipid composition of tumors and homologous tissues of rats exposed to dimethylnitrosamine].
    Eksperimental'naia onkologiia, 1984, Volume: 6, Issue:4

    Topics: Animals; Dimethylnitrosamine; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Male; Phospholipids; Rats; Time Factors

1984
The mechanism of cocarcinogenic action of ethanol in rat liver.
    IARC scientific publications, 1984, Issue:56

    Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA Replication; Ethanol; Liver; Liver Neoplasms; Nitrosamines; Rats

1984
Carcinogenesis in rats by nitrosodimethylamine and other nitrosomethylalkylamines at low doses.
    Cancer letters, 1984, Volume: 22, Issue:1

    Topics: Animals; Dimethylnitrosamine; Drinking; Esophageal Neoplasms; Female; Hemangiosarcoma; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Nitrosamines; Nose Neoplasms; Rats; Rats, Inbred Strains; Time Factors

1984
Chemical liver carcinogenesis: monitoring of the process by flow cytometric DNA measurements.
    Environmental health perspectives, 1983, Volume: 50

    Topics: 2-Acetylaminofluorene; Animals; Cell Division; Clone Cells; Dimethylnitrosamine; DNA, Neoplasm; Flow Cytometry; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Ploidies; Rats

1983
Effect of chronic alcohol consumption on tumor incidence due to dimethylnitrosamine administration.
    Journal of cancer research and clinical oncology, 1983, Volume: 106, Issue:1

    Topics: Alcoholism; Animals; Body Weight; Dimethylnitrosamine; Ethanol; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred Strains

1983
Chemicals, evolution, and cancer development: Rous-Whipple Award Lecture.
    The American journal of pathology, 1982, Volume: 108, Issue:3

    Topics: Adult; Aflatoxin B1; Aflatoxins; Animals; Biological Evolution; Carcinogens; Carcinogens, Environmental; Cell Differentiation; Cytoplasm; Diethylnitrosamine; Dimethylnitrosamine; Humans; Liver; Liver Neoplasms; Methylazoxymethanol Acetate; Mice; Models, Biological; Neoplasms; Neoplasms, Experimental; Precancerous Conditions; Rats; Time Factors

1982
Enhancement by testosterone of dimethylnitrosamine carcinogenesis in lung, liver and kidney of inbred NZR/Gd female rats.
    Carcinogenesis, 1983, Volume: 4, Issue:5

    Topics: Animals; Castration; Dimethylnitrosamine; Female; Kidney Neoplasms; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Starvation; Testosterone

1983
Species specificity in nitrosamine carcinogenesis.
    Basic life sciences, 1983, Volume: 24

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Rats; Species Specificity; Structure-Activity Relationship; Urinary Bladder Neoplasms

1983
Cytogenetic changes during the early stages of liver carcinogenesis in Chinese hamster: an in vivo--in vitro comparison.
    Cancer genetics and cytogenetics, 1983, Volume: 10, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Cricetinae; Cricetulus; Dimethylnitrosamine; Karyotyping; Liver; Liver Neoplasms; Male; Metaphase; Neoplasms, Experimental

1983
Esophageal carcinogenesis in F344 rats by nitrosomethylethylamines substituted in the ethyl group.
    Journal of the National Cancer Institute, 1982, Volume: 68, Issue:4

    Topics: Animals; Dimethylnitrosamine; Esophageal Neoplasms; Liver Neoplasms; Male; Rats; Rats, Inbred F344

1982
Liver tumours after single dose dimethylnitrosamine, low and high protein diet, and phenobarbitone.
    Carcinogenesis, 1982, Volume: 3, Issue:6

    Topics: Animals; Dietary Proteins; Dimethylnitrosamine; Liver Neoplasms; Male; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred Strains

1982
Induction of preneoplastic and neoplastic lesions in rats treated N-nitroso compounds.
    IARC scientific publications, 1982, Issue:41

    Topics: Animals; Butylhydroxybutylnitrosamine; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1982
Toxic and carcinogenic effects of dimethylnitrosamine (DMNA) in the blue fox (Alopex lagopus).
    Acta veterinaria Scandinavica, 1981, Volume: 22, Issue:3-4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Female; Foxes; Hemangiosarcoma; Liver; Liver Diseases; Liver Neoplasms; Male; Necrosis; Neoplasms, Experimental

1981
Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis.
    Journal of supramolecular structure and cellular biochemistry, 1981, Volume: 17, Issue:3

    Topics: Alkylation; Animals; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA; DNA Repair; Liver; Liver Neoplasms; Mesocricetus; Methylation; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Rats; Structure-Activity Relationship

1981
[N-nitroso-compounds of pickles in the areas with high incidence of digestive cancers and their mutagenic effects].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1994, Volume: 28, Issue:4

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Food Preservation; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Micronucleus Tests; Stomach Neoplasms; Vegetables; Water Pollutants, Chemical

1994
Strong promoting effect of Opisthorchis viverrini infection on dimethylnitrosamine-initiated hamster liver.
    Cancer letters, 1994, Apr-01, Volume: 78, Issue:1-3

    Topics: Animals; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cocarcinogenesis; Cricetinae; Dimethylnitrosamine; Liver Neoplasms; Male; Mesocricetus; Opisthorchiasis

1994
Decreased dimethylnitrosamine-induced O6- and N7-methyldeoxyguanosine levels correlate with development and progression of lesions in rat hepatocarcinogenesis.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344

1993
O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jul-15, Volume: 90, Issue:14

    Topics: Animals; Animals, Suckling; Dimethylnitrosamine; Enzyme Induction; Female; Injections, Intraperitoneal; Liver; Liver Neoplasms; Male; Methyltransferases; Mice; Mice, Inbred C3H; Mice, Transgenic; O(6)-Methylguanine-DNA Methyltransferase; Sex Characteristics; Sulfates; Zinc; Zinc Sulfate

1993
Effect of Clonorchis sinensis infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian golden hamsters.
    The Korean journal of parasitology, 1993, Volume: 31, Issue:1

    Topics: Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Bile Ducts; Clonorchiasis; Cocarcinogenesis; Cricetinae; Dimethylnitrosamine; Fibrosis; Hyperplasia; Liver; Liver Neoplasms; Mesocricetus; Necrosis

1993
Focal altered compartmentation of repetitive B2 (Alu-like) sequences in rat liver following hepatocarcinogen exposure.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:5

    Topics: Animals; Base Sequence; Blotting, Northern; Carcinogens; Carcinoma, Hepatocellular; Cell Compartmentation; Dimethylnitrosamine; In Situ Hybridization; Liver Neoplasms; Male; Molecular Sequence Data; Nucleic Acid Conformation; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Repetitive Sequences, Nucleic Acid; RNA, Antisense; RNA, Messenger; Thioacetamide; Time Factors

1996
Depletion of hepatocyte nuclear estrogen receptor expression is associated with promotion of tamoxifen induced GST-P foci to tumours in rat liver.
    Carcinogenesis, 1997, Volume: 18, Issue:5

    Topics: Adenoma; Aflatoxins; Animals; Carcinoma; Cell Compartmentation; Cell Nucleus; Dimethylnitrosamine; Female; Glutathione S-Transferase pi; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Receptors, Estrogen; Tamoxifen; Thioacetamide

1997
High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Animals; Dimethylnitrosamine; Female; Liver Neoplasms; Lung Neoplasms; Male; Methyltransferases; Mice; Mice, Knockout; O(6)-Methylguanine-DNA Methyltransferase; Sex Factors

1997
Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells.
    Mutation research, 1999, May-17, Volume: 441, Issue:2

    Topics: Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Survival; Dimethyl Sulfoxide; Dimethylnitrosamine; DNA; DNA Damage; Electrophoresis; Humans; Image Processing, Computer-Assisted; Liver Neoplasms; Methylnitrosourea; Microscopy, Fluorescence; Mutagenicity Tests; Mutagens; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Solvents; Trypsin; Tumor Cells, Cultured

1999
Carcinogenic N-nitro-dimethylamine from the reaction of the analgesic amidopyrine and nitrite extracted from foodstuffs.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1975, Nov-25, Volume: 84, Issue:3

    Topics: Aminopyrine; Digestion; Dimethylnitrosamine; Food; Food Preservatives; Food-Processing Industry; Gastric Juice; Germany, West; Humans; Hydrogen-Ion Concentration; Legislation, Drug; Liver Neoplasms; Meat; Nitrites; Nitrosamines; Vegetables

1975
On the protective role of vitamin B2 in mice administered dimethylnitrosamine.
    JPMA. The Journal of the Pakistan Medical Association, 1979, Volume: 29, Issue:7

    Topics: Animals; Dimethylnitrosamine; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Riboflavin

1979
Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Mar-19, Volume: 85, Issue:3

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Disulfiram; Esophageal Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Paranasal Sinus Neoplasms; Rats

1976
Alteration of hepatocytes by subcarcinogenic exposure to n-2-fluorenylacetamide.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Chick Embryo; Chromosome Aberrations; Diet; Dimethylnitrosamine; Fluorenes; Hydroxyacetylaminofluorene; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred ACI

1975
Effect of a single treatment with the alkylating carcinogens dimethynitrosamine, diethylnitrosamine and methyl methanesulphonate, on liver regenerating after partial hepatectomy. I. Test for induction of liver carcinomas.
    Chemico-biological interactions, 1975, Volume: 10, Issue:5

    Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethylnitrosamine; Female; Hepatectomy; Kidney Neoplasms; Liver; Liver Neoplasms; Liver Regeneration; Lung Neoplasms; Male; Mesylates; Methyl Methanesulfonate; Neoplasm Metastasis; Nitrosamines; Rats; Time Factors

1975
Null carcinogenic effect of large doses of nitrosoproline and nitrosohydroxyproline in Wistar rats.
    Food and cosmetics toxicology, 1976, Volume: 14, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; Drug Synergism; Fatty Acids, Unsaturated; Hydroxyproline; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Proline; Rats

1976
Methyldopa binding to cells in culture.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:1

    Topics: Acetaminophen; Allopurinol; Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Deferoxamine; Dimethylnitrosamine; Edetic Acid; Furosemide; Glutathione; Liver Neoplasms; Maleates; Methyldopa; Neoplasms, Experimental; Protein Binding; Rats; Superoxide Dismutase; Time Factors; Xanthines

1977
The induction of tumors in Rana temporaria with nitrosamines.
    Neoplasma, 1977, Volume: 24, Issue:3

    Topics: Adenoma; Animals; Anura; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethylnitrosamine; Hematopoietic System; Liver Neoplasms; Neoplasms, Experimental; Nitrosamines; Rana temporaria; Time Factors

1977
Cytoplasmic changes in level and distribution of glucose-6-phosphatase activities from rat liver during diethylnitrosamine-induced carcinogenesis.
    Chemico-biological interactions, 1977, Volume: 18, Issue:3

    Topics: Animals; Body Weight; Cytoplasm; Dimethylnitrosamine; Female; Glucose-6-Phosphatase; In Vitro Techniques; Liver; Liver Neoplasms; Microsomes, Liver; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Time Factors

1977
[Antigenic rearrangement in the liver of mice and rats as a result of simultaneous effect of the carcinogens].
    Tsitologiia, 1977, Volume: 19, Issue:7

    Topics: Animals; Antigens, Neoplasm; Azo Compounds; Carcinoma, Hepatocellular; Dimethylnitrosamine; Liver; Liver Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosamines; o-Aminoazotoluene; Organ Specificity; p-Dimethylaminoazobenzene; Rats

1977
Tumor frequency and characteristics after a single dose of dimethylnitrosamine or diethylnitrosamine in partially hepatectomized rats.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1977, Volume: 90, Issue:1

    Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Dimethylnitrosamine; Hepatectomy; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Sarcoma; Teratoma; Thymus Neoplasms

1977
Carcinogenicity and acute toxicity of dimethylnitrosamine in rainbow trout (Salmo gairdneri).
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:5

    Topics: Animals; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Species Specificity; Trout

1978
Differential effects of beta-naphthoflavone and pregnenolone-16alpha-carbonitrile on dimethylnitrosamine-induced hepatocarcinogenesis.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:2

    Topics: Animals; Biotransformation; Carcinoma, Hepatocellular; Dimethylnitrosamine; Drug Interactions; Flavonoids; Hemangiosarcoma; Liver Neoplasms; Male; Naphthalenes; Neoplasms, Experimental; Nitrosamines; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Rats

1978
Low level of unscheduled [3H] thymidine incorporation into hyperplastic nodule and hepatoma cells after exposure to dimethylnitrosamine in vivo.
    Chemico-biological interactions, 1978, Volume: 23, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; DNA; DNA, Neoplasm; Hyperplasia; Liver; Liver Neoplasms; Male; Nitrosamines; Rats; Thymidine

1978
A synergistic effect of nitrosodimethylamine on sterigmatocystin carcinogenesis in rats.
    Food and cosmetics toxicology, 1978, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Dimethylnitrosamine; Drug Synergism; Leydig Cell Tumor; Liver Neoplasms; Male; Nitrosamines; Rats; Sterigmatocystin; Testicular Neoplasms; Xanthenes

1978
[Induction of hepatocellular carcinoma in Mastomys using a single application of dimethylnitrosamine].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1978, Volume: 62

    Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; Female; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions

1978
Propionibacterium acnes-mediated humoral immune responses to tumor-specific antigens on rat liver cells transformed in vitro by chemical carcinogens.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:6

    Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Liver Neoplasms; Methylnitronitrosoguanidine; Neoplasms, Experimental; Propionibacterium acnes; Rats

1978
Vascular liver tumors induced in Mastomys (Praomys) natalensis by single or twofold administration of dimethylnitrosamine.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:5

    Topics: Animals; Dimethylnitrosamine; Female; Hemangioendothelioma; Liver Neoplasms; Male; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosamines

1979
Kupffer cell sarcoma in rats after exposure to small doses of dimethylnitrosamine and N-2-acetylaminofluorene during hepatic regeneration.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Dimethylnitrosamine; Fluorenes; Liver Neoplasms; Liver Regeneration; Lymphoma, Large B-Cell, Diffuse; Male; Microscopy, Electron; Nitrosamines; Rats; Sarcoma, Experimental

1979
Effect of phenobarbital on induction of liver and lung tumors by dimethylnitrosamine in newborn mice.
    Gan, 1979, Volume: 70, Issue:5

    Topics: Adenoma; Animals; Animals, Newborn; Dimethylnitrosamine; Drug Synergism; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms, Experimental; Phenobarbital

1979
Persistence of DNA damage during development of liver angiosarcoma in rats fed dimethylnitrosamine.
    Cancer research, 1979, Volume: 39, Issue:5

    Topics: Animals; Centrifugation, Density Gradient; Dimethylnitrosamine; DNA, Neoplasm; Hemangiosarcoma; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Sarcoma, Experimental; Time Factors

1979
The carcinogenic effect of dimethylnitrosamine in laboratory bred European hamsters (Cricetus cricetus).
    Cancer letters, 1978, Volume: 4, Issue:1

    Topics: Animals; Animals, Laboratory; Carcinogens; Cricetinae; Dimethylnitrosamine; Female; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Ovarian Neoplasms

1978
Statistical aspects of extrapolation of dichotomous dose-response data.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:1

    Topics: Animals; Carcinogens; Diethylstilbestrol; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Humans; Liver Neoplasms; Male; Mammary Neoplasms, Experimental; Mathematics; Mice; Neoplasms, Experimental; Rats; Risk

1978
Alkylation of rat liver DNA by dimethylnitrosamine: effect of dosage on O6-methylguanine levels.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:3

    Topics: Alkylating Agents; Animals; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Female; Guanine; Liver; Liver Neoplasms; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Rats

1977
Effects of nine N-nitroso compounds on the specific radioactivity of liver proteins after injection of [14C]leucine into rats.
    Cancer research, 1977, Volume: 37, Issue:5

    Topics: Animals; Cycloleucine; Diethylnitrosamine; Dimethylnitrosamine; Leucine; Liver; Liver Neoplasms; Male; Methylnitrosourea; Morpholines; Necrosis; Nitroso Compounds; Piperazines; Piperidines; Proteins; Rats; Sarcosine; Time Factors

1977
Effect of intestinal microflora suppression on liver carcinogenicity of dimethylnitrosamine in Syrian hamsters.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cricetinae; Dimethylnitrosamine; Female; Germ-Free Life; Intestines; Liver Neoplasms; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines

1977
Newer insights into the pathogenesis of liver cancer.
    The American journal of pathology, 1977, Volume: 89, Issue:2

    Topics: Aflatoxins; Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnitrosamine; Hepatectomy; Hydroxyacetylaminofluorene; Liver Neoplasms; Methylazoxymethanol Acetate; Methyldimethylaminoazobenzene; Neoplasms, Experimental; Precancerous Conditions; Skin Neoplasms

1977
The effect of temperature during the diethylnitrosamine treatment on liver tumorigenesis in the fish, Oryzias latipes.
    European journal of cancer, 1977, Volume: 13, Issue:10

    Topics: Animals; Dimethylnitrosamine; Female; Fishes; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Temperature

1977
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens.
    Cancer research, 1976, Volume: 36, Issue:11 Pt 1

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; Drug Resistance; Ethionine; Hyperplasia; Liver; Liver Neoplasms; Male; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; RNA

1976
Methylated purines in the deoxyribonucleic acid of various Syrian-golden-hamster tissues after administration of a hepatocarcinogenic dose of dimethylnitrosamine.
    The Biochemical journal, 1976, Sep-01, Volume: 157, Issue:3

    Topics: Adenine; Animals; Cricetinae; Dimethylnitrosamine; DNA; Guanine; Kidney; Liver; Liver Neoplasms; Lung; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Purines

1976
Enhancement of hepatic and renal tumorigenesis with thyroidectomized NZR/Gd rats treated with dimethylnitrosamine.
    Journal of surgical oncology, 1976, Volume: 8, Issue:6

    Topics: Animals; Dimethylnitrosamine; Female; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred Strains; Thyroidectomy

1976
Toxic and carcinogenic effects of nitrosodimethylamine in mink.
    IARC scientific publications, 1976, Issue:14

    Topics: Animals; Carcinogens; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Hemangioma; Liver; Liver Neoplasms; Male; Mink; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosamines; Time Factors

1976
Nature of early appearing, carcinogen-induced liver lesions to iron accumulation.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Dimethylnitrosamine; Hyperplasia; Iron; Liver Neoplasms; Male; Mitosis; Neoplasms, Experimental; Precancerous Conditions; Rats

1976
The activation of dimethylnitrosamine (DMN) by yeast extracts.
    British journal of cancer, 1975, Volume: 31, Issue:5

    Topics: Dimethylnitrosamine; Enzyme Activation; Liver Neoplasms; Nitrosamines; Saccharomyces cerevisiae

1975
Transformed liver cells obtained in culture from hepatectomized rats treated with dimethylnitrosamine (dMN).
    British journal of cancer, 1975, Volume: 31, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Nitrosamines; Rats

1975
[The carcinogenic activity of small concentrations of nitrosodimethylamine when inhaled].
    Voprosy onkologii, 1975, Volume: 21, Issue:6

    Topics: Animals; Dimethylnitrosamine; Female; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Nitrosamines; Rats

1975
Partial hepatectomy and toxicity of dimethyl-nitrosamine and carbon tetrachloride, in relation to the carcinogenic action of dimethylnitrosamine.
    British journal of cancer, 1975, Volume: 32, Issue:5

    Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hepatectomy; Kidney Neoplasms; Lethal Dose 50; Liver Neoplasms; Male; Mice; Microsomes, Liver; Mitosis; Nitrosamines; Rats

1975
The carcinogenic effect of dimethylnitrosamine on the Chinese hamster (Cricetulus griseus).
    Cancer letters, 1975, Volume: 1, Issue:1

    Topics: Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Hemangioendothelioma; Injections, Subcutaneous; Liver Neoplasms; Male; Mesocricetus; Mice; Neoplasms, Experimental; Nitrosamines; Species Specificity

1975
Carcinogenic effects of different nitroso-compounds in Chinese hamsters. I. Dimethylnitrosamine and N-diethylnitrosamine.
    British journal of cancer, 1976, Volume: 33, Issue:4

    Topics: Animals; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Esophageal Neoplasms; Female; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; Stomach Neoplasms

1976
Sequential phenotypic and biochemical alterations during chemical hepatocarcinogenesis.
    Cancer research, 1976, Volume: 36, Issue:7 PT 2

    Topics: 2-Acetylaminofluorene; Animals; Cell Aggregation; Chromatin; Dimethylnitrosamine; Lectins; Liver Neoplasms; Male; Neoplasm Proteins; Neoplasms, Experimental; Phenotype; Precancerous Conditions; Rats; Rats, Inbred ACI

1976
Cytokeratin filaments of the liver of BALB/c mice as a sensitive marker of liver damage. Computer-aided characterization with the image analysing system "IBAS".
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1992, Volume: 44, Issue:4

    Topics: Actin Cytoskeleton; Adenoma; Animals; Biomarkers, Tumor; Colchicine; Dimethylnitrosamine; Female; Image Processing, Computer-Assisted; Keratins; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence

1992
Characterization of ethanol's enhancement of tumorigenesis by N-nitrosodimethylamine in mice.
    Carcinogenesis, 1992, Volume: 13, Issue:11

    Topics: Adenoma; Animals; Body Weight; Dimethylnitrosamine; Drug Synergism; Ethanol; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mice

1992
The exposure of carcinogen-initiated primary neonatal rat hepatocytes to tumor promoters modulates both the transcripts and the enzymatic activity of nuclear poly(ADP-ribose) polymerase.
    Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3

    Topics: Animals; Animals, Newborn; Benzamides; Calcium; Cell Cycle; Cell Nucleus; Cells, Cultured; Dimethylnitrosamine; DNA Replication; Epidermal Growth Factor; Female; Kinetics; Liver; Liver Neoplasms; Maternal-Fetal Exchange; Mutagenesis; Phenobarbital; Poly(ADP-ribose) Polymerases; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred Strains; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thymidine; Transcription, Genetic

1992
[35S]methionine interaction with rat liver tRNA and effect of chemical carcinogens.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:7

    Topics: Animals; Chromatography, High Pressure Liquid; Dimethylnitrosamine; DNA; Ethionine; Hepatectomy; Liver; Liver Neoplasms; Male; Methionine; Methylnitrosourea; Rats; Rats, Inbred Strains; Reference Values; RNA, Transfer; Sulfur Radioisotopes; Tissue Distribution

1991
Quantity and saturation degree of dietary fats as modulators of oxidative stress and chemically-induced liver tumours in rats.
    International journal of cancer, 1990, Oct-15, Volume: 46, Issue:4

    Topics: Animals; Biomarkers; Blood Chemical Analysis; Cell Transformation, Neoplastic; Cholesterol; Dietary Fats; Dimethylnitrosamine; Glutathione; Indomethacin; Lipid Peroxidation; Lipids; Liver; Liver Neoplasms; Male; Peptidyl Transferases; Rats; Rats, Inbred Strains; Triglycerides; Weight Gain

1990
H4IIEC3 rat hepatoma cells activate N-nitrosodimethylamine but are resistant to the genotoxic products.
    Mutagenesis, 1989, Volume: 4, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cricetinae; Cricetulus; Dimethylnitrosamine; Drug Resistance; Liver Neoplasms; Male; Micronucleus Tests; Mutation; Rats; Rats, Inbred Strains; Tumor Cells, Cultured

1989
Transforming activity of DNA from rat liver tumors induced by the carcinogen methyl(acetoxymethyl)nitrosamine.
    Molecular carcinogenesis, 1988, Volume: 1, Issue:1

    Topics: Animals; Blotting, Southern; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA Restriction Enzymes; DNA, Neoplasm; Liver Neoplasms; Male; Mice; Mice, Nude; Molecular Weight; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Rats; Transfection

1988
Promotion by sodium barbital of renal cortical and transitional cell tumors, but not intestinal tumors, in F344 rats given methyl(acetoxymethyl)nitrosamine, and lack of effect of phenobarbital, amobarbital, or barbituric acid on development of either rena
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Adenoma; Amobarbital; Animals; Barbital; Barbiturates; Carcinogens; Carcinoma; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cocarcinogenesis; Dimethylnitrosamine; Intestinal Neoplasms; Kidney Neoplasms; Liver Neoplasms; Phenobarbital; Rats; Rats, Inbred F344; Thyroid Neoplasms

1989
Effects of a single dose of polychlorinated biphenyls to infant mice on N-nitrosodimethylamine-initiated lung and liver tumors.
    International journal of cancer, 1986, Jul-15, Volume: 38, Issue:1

    Topics: Animals; Animals, Newborn; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, Gas; Cocarcinogenesis; Dimethylnitrosamine; Dose-Response Relationship, Drug; Fertilization; Litter Size; Liver; Liver Neoplasms; Lung Neoplasms; Male; Mice; Polychlorinated Biphenyls; Precancerous Conditions; Sex Factors; Tissue Distribution

1986
Effect of (+)-catechin, dimethyl sulfoxide and ethanol on the microsome-mediated metabolism of two hepatocarcinogens, N-nitrosodimethylamine and aflatoxin B1.
    IARC scientific publications, 1987, Issue:84

    Topics: Aflatoxin B1; Aflatoxins; Animals; Catechin; Cricetinae; Dimethyl Sulfoxide; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Ethanol; Liver Neoplasms; Microsomes, Liver

1987
Possible role of certain antioxidant enzymes in dimethylnitrosamine-induced liver carcinogenesis.
    International journal of cancer, 1988, Nov-15, Volume: 42, Issue:5

    Topics: Animals; Antioxidants; Catalase; Dimethylnitrosamine; DNA Damage; Glutathione Peroxidase; Liver Neoplasms; Male; Rats; Rats, Inbred Strains; Superoxide Dismutase

1988
Various short-term assays and two long-term studies with the plasticizer di(2-ethylhexyl)phthalate in the Syrian golden hamster.
    Carcinogenesis, 1988, Volume: 9, Issue:1

    Topics: Air Pollutants; Animals; Biotransformation; Cell Line; Cocarcinogenesis; Cricetinae; Diethylhexyl Phthalate; Dimethylnitrosamine; DNA Damage; Female; Gene Amplification; Liver Neoplasms; Male; Mesocricetus; Mutagenicity Tests; Phthalic Acids

1988
Studies on the mechanism of the acute and carcinogenic effects of N-nitrosodimethylamine on mink liver.
    Journal of toxicology and environmental health, 1988, Volume: 23, Issue:2

    Topics: Animals; Dimethylnitrosamine; Female; Formaldehyde; In Vitro Techniques; Liver; Liver Neoplasms; Male; Mink; Nucleic Acids; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity

1988
Marked synergism of dimethylnitrosamine carcinogenesis in rats exposed to cadmium.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Animals; Cadmium; Cocarcinogenesis; Dimethylnitrosamine; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Male; Rats; Rats, Inbred Strains; Testicular Neoplasms

1987
Carcinogenic effects of sequential administration of two nitrosamines in Fischer 344 rats.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Animals; Dimethylnitrosamine; Drug Administration Schedule; Esophageal Neoplasms; Female; Kidney Neoplasms; Liver Neoplasms; Liver Neoplasms, Experimental; N-Nitrosopyrrolidine; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344

1986
In vitro colonization ability appears soon after initiation of hepatocarcinogenesis in the rat.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Dimethylnitrosamine; Liver Neoplasms; Male; Phenobarbital; Rats; Rats, Inbred F344

1986
Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Animals; Dimethylnitrosamine; DNA, Neoplasm; Guanine; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Neoplasms, Experimental; Nicotiana; Nitrosamines; Nose Neoplasms; Plants, Toxic; Rats

1986
Quantitative relationship between hepatocytic neoplasms and islands of cellular alteration during hepatocarcinogenesis in the male F344 rat.
    The American journal of pathology, 1985, Volume: 119, Issue:2

    Topics: Animals; Carcinogens; Dimethylnitrosamine; Liver Neoplasms; Male; Phenobarbital; Rats; Rats, Inbred F344; Time Factors

1985
Modulation of repair of O6-methylguanine in parenchymal and nonparenchymal liver cells of rats treated with dimethylnitrosamine.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Alkylation; Animals; Carbon Radioisotopes; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Liver Neoplasms; Male; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains

1985
Comparative changes in rat liver cytosolic proteins by mirex, diethylnitrosamine, and dimethylnitrosamine exposure.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:2

    Topics: Animals; Carcinogens; Cocarcinogenesis; Cytosol; Diethylnitrosamine; Dimethylnitrosamine; Female; Insecticides; Liver; Liver Neoplasms; Male; Mirex; Neoplasm Proteins; Phenobarbital; Precancerous Conditions; Protein Biosynthesis; Rats; Rats, Inbred Strains

1985