Page last updated: 2024-08-17

dimethylnitrosamine and Cirrhosis

dimethylnitrosamine has been researched along with Cirrhosis in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.09)18.2507
2000's10 (45.45)29.6817
2010's7 (31.82)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Aoyama, Y; Inaguma, S; Kato, H; Komura, M; Matsuo, Y; Nagayasu, Y; Naiki-Ito, A; Takahashi, S; Takiguchi, S; Tomita, M; Tsuda, H; Xiaochen, K1
George, J; Tsuchishima, M; Tsutsumi, M2
Fukawa, A; Hosono, A; Kobayashi, O; Uchida, M; Yamaguchi, M1
Fukuda, N; Fukushima, A; Inami, M; Matsumoto, Y; Moriyama, M; Soma, M; Tsunemi, A; Ueno, T; Yamada, T1
Fang, H; Li, G; Miyamura, M; Sun, C; Teng, Y; Yokota, J; Yoshioka, S; Zhang, Y1
Hu, Y; Jian, P; Liu, C; Liu, P; Peng, J; Sun, M; Tao, Q; Wu, JZ; Yang, W1
Leu, YL; Pan, TL; Wang, PW; Wu, TH; Wu, TS1
Chen, G; Hu, X; Liu, C; Liu, P; Mu, Y; Sun, M; Wang, G; Zhang, L1
Becker, K; Boger, RJ; Ehrenberg, KR; Hahn, M; Hövelmeyer, N; Jäger, D; Longerich, T; Schuchmann, M; Schulze-Bergkamen, H; Urbanik, T; Waisman, A; Wörns, MA1
Chen, W; Li, F; Liu, C; Liu, P; Lu, X; Wang, X; Xu, G1
Aoki, K; Inoue, K; Kato, N; Kazui, T; Kohara, M; Ohnami, S; Suzuki, K; Yoshida, K; Yoshida, T1
George, J; Takase, S; Tsutsumi, M1
Cui, HY; Hu, YY; Jiang, ZH; Li, FH; Liu, C; Liu, CH; Liu, P; Xu, LM; Yuan, JL1
Bertho-Ruault, C; de Gouville, AC; Gellibert, F; Grygielko, ET; Huet, S; Laping, NJ; Mathews, N; Nguyen, VL; Patikis, A; Woolven, J1
Chiu, YT; Chong, LW; Hsu, YC; Huang, YT; Yang, KC1
Cheng, CC; Chiu, YT; Hsu, YC; Huang, YT; Lin, YL; Wu, CF1
George, J; Tsutsumi, M1
Bak, UB; Lee, JH; Rim, HJ1
Chandrakasan, G; George, J1
Enjoji, M; Kato, M; Kotoh, K; Nakamuta, M; Nakashima, Y; Nawata, H; Ohta, S; Sugimoto, R; Tada, S; Tsuruta, S1
Ala-Kokko, L; Günzler, V; Hoek, JB; Prockop, DJ; Rubin, E1

Reviews

1 review(s) available for dimethylnitrosamine and Cirrhosis

ArticleYear
Metabolism of N-nitrosodimethylamine, methylation of macromolecules, and development of hepatic fibrosis in rodent models.
    Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:9

    Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Disease Susceptibility; Fibroblasts; Fibrosis; Hepatic Stellate Cells; Hepatocytes; Humans; Liver Cirrhosis; Macromolecular Substances; Methylation; Rodentia

2020

Other Studies

21 other study(ies) available for dimethylnitrosamine and Cirrhosis

ArticleYear
Lactoferrin Prevents Hepatic Injury and Fibrosis via the Inhibition of NF-κB Signaling in a Rat Non-Alcoholic Steatohepatitis Model.
    Nutrients, 2021, Dec-23, Volume: 14, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Carcinoma, Hepatocellular; Connexins; Cytokines; Dimethylnitrosamine; Fibrosis; Gap Junction beta-1 Protein; Lactoferrin; Liver; Liver Cirrhosis; Liver Neoplasms; Male; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2021
Epigallocatechin-3-gallate inhibits osteopontin expression and prevents experimentally induced hepatic fibrosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 151

    Topics: Animals; Body Weight; Catechin; Collagen Type I; Collagen Type IV; Dimethylnitrosamine; Fibrosis; Hepatic Stellate Cells; Hyaluronic Acid; Liver; Liver Cirrhosis; Malondialdehyde; Osteopontin; Rats

2022
Bovine milk-derived α-lactalbumin prevents hepatic fibrosis induced by dimethylnitrosamine via nitric oxide pathway in rats.
    Bioscience, biotechnology, and biochemistry, 2017, Volume: 81, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cattle; Dimethylnitrosamine; Fibrosis; Lactalbumin; Liver; Male; Milk; Nitric Oxide; Organ Size; Rats; Rats, Sprague-Dawley; Spleen

2017
Reduction of Dimethylnitrosamine-Induced Liver Fibrosis by the Novel Gene Regulator PI Polyamide Targeting Transforming Growth Factor β1 Gene.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:12

    Topics: Actins; Animals; Cell Line; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; End Stage Liver Disease; Fibrosis; Gene Silencing; Hepatic Stellate Cells; Imidazoles; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 2; Pyrroles; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta

2015
Metabonomics study of the protective effects of Lonicera japonica extract on acute liver injury in dimethylnitrosamine treated rats.
    Journal of pharmaceutical and biomedical analysis, 2010, Sep-21, Volume: 53, Issue:1

    Topics: Animals; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Drugs, Chinese Herbal; Fibrosis; Flowers; Gas Chromatography-Mass Spectrometry; Lonicera; Metabolomics; Phytotherapy; Rats; Rats, Wistar; Time Factors

2010
Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats.
    Laboratory investigation; a journal of technical methods and pathology, 2010, Volume: 90, Issue:12

    Topics: Animals; Apoptosis; Carbon Tetrachloride; Collagen Type I; Dimethylnitrosamine; Fibrosis; Hepatic Stellate Cells; Inflammation; Kupffer Cells; Lipopolysaccharides; Liver Cirrhosis; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2010
Inhibitory effects of Scutellaria baicalensis extract on hepatic stellate cells through inducing G2/M cell cycle arrest and activating ERK-dependent apoptosis via Bax and caspase pathway.
    Journal of ethnopharmacology, 2012, Feb-15, Volume: 139, Issue:3

    Topics: Actins; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Cycle Checkpoints; Cell Death; Collagen; Dimethylnitrosamine; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Hepatic Stellate Cells; Liver; Liver Diseases; Muscle, Smooth; Phytotherapy; Plant Extracts; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Scutellaria baicalensis

2012
Huangqi decoction inhibits apoptosis and fibrosis, but promotes Kupffer cell activation in dimethylnitrosamine-induced rat liver fibrosis.
    BMC complementary and alternative medicine, 2012, Apr-24, Volume: 12

    Topics: Animals; Apoptosis; Caspase 3; Dimethylnitrosamine; Drugs, Chinese Herbal; Fibrosis; Hepatocytes; Humans; Kupffer Cells; Liver Cirrhosis; Male; Protective Agents; Rats; Rats, Wistar; Transforming Growth Factor beta1

2012
Liver specific deletion of CYLDexon7/8 induces severe biliary damage, fibrosis and increases hepatocarcinogenesis in mice.
    Journal of hepatology, 2012, Volume: 57, Issue:5

    Topics: Animals; Biliary Tract Diseases; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Dimethylnitrosamine; Disease Models, Animal; Exons; Fibrosis; Gene Deletion; Genetic Predisposition to Disease; Homeostasis; In Vitro Techniques; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenobarbital; Phenotype; Risk Factors

2012
[Role of hepatic sinusoidal endothelium injury in hepatic fibrogenesis induced by dimethylnitrosamine in rats].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:6

    Topics: Actins; Animals; Dimethylnitrosamine; Endothelium, Vascular; Fibrosis; Immunohistochemistry; Liver; Male; Muscle, Smooth; Rats; Rats, Wistar; Time Factors; von Willebrand Factor

2002
Adenovirus-mediated gene transfer of interferon alpha improves dimethylnitrosamine-induced liver cirrhosis in rat model.
    Gene therapy, 2003, Volume: 10, Issue:9

    Topics: Adenoviridae; Animals; Dimethylnitrosamine; Fibrosis; Genetic Therapy; Genetic Vectors; Immunotherapy; Injections, Subcutaneous; Interferon-gamma; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Transduction, Genetic

2003
Expression of hyaluronic acid in N-nitrosodimethylamine induced hepatic fibrosis in rats.
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:2

    Topics: Actins; Animals; Body Weight; Dimethylnitrosamine; Fibrosis; Hyaluronan Receptors; Hyaluronic Acid; Immunohistochemistry; Liver; Male; Muscle, Smooth; N-Methylaspartate; Necrosis; Nitrosamines; Organ Size; Rats; Time Factors

2004
[Effects of Fuzheng Huayu recipe on renal toxic interstitial fibrosis in rats].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2004, Volume: 2, Issue:5

    Topics: Animals; Creatinine; Dimethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herbal; Fibrosis; Hydroxyproline; Kidney; Male; Nephritis, Interstitial; Rats; Rats, Wistar; Renal Insufficiency

2004
Discovery of 4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H- pyran-4-yl)benzamide (GW788388): a potent, selective, and orally active transforming growth factor-beta type I receptor inhibitor.
    Journal of medicinal chemistry, 2006, Apr-06, Volume: 49, Issue:7

    Topics: Activin Receptors, Type I; Acute Disease; Administration, Oral; Animals; Benzamides; Collagen Type I; Collagen Type I, alpha 1 Chain; Dimethylnitrosamine; Fibrosis; Kidney; Liver Cirrhosis; Male; Models, Molecular; Protein Serine-Threonine Kinases; Puromycin Aminonucleoside; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA, Messenger; Structure-Activity Relationship

2006
Anti-fibrotic effects of thalidomide on hepatic stellate cells and dimethylnitrosamine-intoxicated rats.
    Journal of biomedical science, 2006, Volume: 13, Issue:3

    Topics: Actins; Animals; Collagen; Dimethylnitrosamine; Fibrosis; I-kappa B Proteins; Immunosuppressive Agents; Liver; Liver Cirrhosis, Experimental; Muscle, Smooth; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Thalidomide; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2006
Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:1

    Topics: Actins; Alkaloids; Analysis of Variance; Animals; Benzylisoquinolines; Blotting, Western; Cell Line; Dimethylnitrosamine; Fibrosis; Intercellular Adhesion Molecule-1; Liver Cirrhosis, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2007
siRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats.
    Gene therapy, 2007, Volume: 14, Issue:10

    Topics: Actins; Animals; Blotting, Western; Cells, Cultured; Connective Tissue Growth Factor; Dimethylnitrosamine; Fibrosis; Gene Silencing; Genetic Therapy; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Transfection; Transforming Growth Factor beta1

2007
Effect of Clonorchis sinensis infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian golden hamsters.
    The Korean journal of parasitology, 1993, Volume: 31, Issue:1

    Topics: Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Bile Ducts; Clonorchiasis; Cocarcinogenesis; Cricetinae; Dimethylnitrosamine; Fibrosis; Hyperplasia; Liver; Liver Neoplasms; Mesocricetus; Necrosis

1993
Biochemical abnormalities during the progression of hepatic fibrosis induced by dimethylnitrosamine.
    Clinical biochemistry, 2000, Volume: 33, Issue:7

    Topics: Animals; Blood Glucose; Cholesterol; Creatinine; Dimethylnitrosamine; Fibrosis; Hydroxyproline; Insulin; Lipid Peroxides; Liver; Male; Phosphates; Rats; Rats, Wistar; Time Factors; Urea; Uric Acid

2000
Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
    International journal of molecular medicine, 2001, Volume: 8, Issue:5

    Topics: Animals; Body Weight; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen Type I; Dimethyl Sulfoxide; Dimethylnitrosamine; Fibrosis; Free Radical Scavengers; Gene Expression Regulation; Hydroxyproline; Kupffer Cells; Lipopolysaccharides; Liver; Liver Diseases; Luciferases; Male; NF-kappa B; Nitric Oxide; Organ Size; Promoter Regions, Genetic; Rats; Rats, Wistar; Recombinant Fusion Proteins; RNA, Messenger; Severity of Illness Index; Tumor Necrosis Factor-alpha; Weight Loss

2001
Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:1

    Topics: Animals; Biomarkers; Carbon Tetrachloride Poisoning; Collagen; Dimethylnitrosamine; Female; Fibrosis; Hydroxyproline; Immunoassay; Inflammation; Liver; Liver Cirrhosis, Experimental; Macromolecular Substances; Peptide Fragments; Procollagen; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger

1992