Compounds > dimethylnitrosamine
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dimethylnitrosamine and Cirrhoses, Experimental Liver

dimethylnitrosamine has been researched along with Cirrhoses, Experimental Liver in 121 studies

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-199014 (11.57)18.7374
1990's30 (24.79)18.2507
2000's46 (38.02)29.6817
2010's28 (23.14)24.3611
2020's3 (2.48)2.80

Authors

AuthorsStudies
Aoyama, Y; Inaguma, S; Kato, H; Nagayasu, Y; Naiki, T; Naiki-Ito, A; Suzuki, S; Takahashi, S; Yeewa, R1
Li, B; Liu, J; Xia, C; Xin, X; Yu, H; Zhang, L; Zhou, J; Zhu, W1
Liu, CH; Tang, LR; Tao, YY; Wang, HN1
Antushevich, AE; Grebenyuk, AN; Khalyutin, DA; Yartseva, AA1
Jin, JY; Li, YY; Liu, SY; Ma, YM; Wang, GF; Wang, TM; Wang, YH; Wang, ZT; Wu, JS; Yang, L; Zheng, M1
Cai, L; Feng, L; Huo, X; Jv, Y; Ma, X; Ning, J; Sun, C; Tian, X; Wang, C; Yu, Z; Zhang, B; Zhang, H1
Chung, HY; Kim, KW; Moon, JO; Shin, DS; Yoon, S1
Feng, Q; Hu, YY; Li, XM; Peng, JH1
Bai, HB; Fu, XC; Hu, R; Qian, Y; Shen, LM1
Jin, L; Shan, W; Shu, D; Wang, H; Wang, T; Wu, J; Xiong, S; Zhang, S1
Ling, QF; Liu, CY; Shang, MM; Wu, XP; Zhang, Q1
Ho, CT; Lai, CS; Lee, YL; Li, S; Pan, MH; Tsai, CY; Wan, X; Weerawatanakorn, M1
Choi, MK; Han, JM; Kim, HG; Lee, JS; Park, HJ; Son, CG; Wang, JH1
He, S; Jiang, MD; Mu, D; Weng, M; Zeng, WZ; Zhang, Y; Zheng, SM; Zhou, DJ1
He, W; Li, B; Ouyang, C; Shi, F; Zhang, K; Zhang, X; Zhou, SF; Zhou, ZW; Zhu, X1
Fukuda, N; Fukushima, A; Inami, M; Matsumoto, Y; Moriyama, M; Soma, M; Tsunemi, A; Ueno, T; Yamada, T1
Bak, J; Cheong, KO; Chung, HY; Je, NK; Kim, KW; Lee, C; Moon, JO; Shin, DS; Yoon, S1
Chen, QL; Liu, P; Lu, YY; Song, YN; Su, SB; Wang, ZT; Yang, L; Zhang, GB1
Chen, G; Chen, J; Liu, P; Mu, Y; Ren, S; Sun, M; Tong, X; Wang, X; Zhang, H; Zhou, Y1
Wang, LT; Zhang, B1
Hu, YY; Li, FH; Liu, CH; Liu, P; Tang, ZP; Wang, XB; Xu, LM1
Fujimoto, J; Hirakawa, K; Hirano, T; Horiguchi, K; Ueki, T1
Liu, P; Tang, ZP; Wang, XB1
Huang, HF; Lei, CL; Li, CQ; Li, WL; Li, XY; Tan, XH; Xie, M; Zhang, AM; Zou, SR1
Hong, SS; Hong, SW; Jung, KH; Lee, DH; Lee, HS; Park, IS; Suh, JK; Zheng, HM1
Choi, CY; Choi, JH; Chung, YC; Hwang, YP; Jeong, HG1
Liu, C; Liu, P; Lv, J; Wang, L; Yan, X; Zeng, Z1
Liu, C; Liu, P; Tao, Q1
Chiu, YT; Chong, LW; Hsu, YC; Huang, YT; Yang, KC2
Chen, GF; Lu, Y; Tong, X1
Abe, M; Hashimoto, O; Iwamoto, H; Koga, H; Masuda, H; Naitou, M; Nakamura, T; Sata, M; Torimura, T; Tsutsumi, V; Ueno, T1
Ding, H; Lin, SH; Ma, JJ; Wang, WP; Yu, Q; Zeng, WJ; Zhang, H; Zhu, HG1
Lu, C; Ping, J; Xu, H; Xu, LM; Zhou, Y1
Chen, GF; Chen, JM; Liu, P; Mu, YP; Ning, BB; Ren, S; Zhang, H; Zhang, LJ; Zhang, WM; Zhang, X1
Bian, YQ; Cao, HY; Chen, GF; Liu, C; Liu, J; Liu, P; Lu, Y; Ning, BB; Sun, MY1
Asano, S; Hata, J; Ikeda, E; Uno, H1
Cui, T; Hamada, A; Kusunose, M; Kyotani, S; Miyamura, M; Nishioka, Y; Ono, M; Qiu, B; Yoshioka, S1
Ahn, BO; Cheong, JY; Cho, SW; Hahm, KB; Kim, DH; Kim, JH; Kim, WB; Kim, YB; Lee, KM; Oh, TY; Yoo, BM1
Enzan, H; Guo, LM; Hayashi, Y; Hiroi, M; Jin, YL; Kuroda, N; Miyazaki, E; Nakayama, H; Saibara, T; Toi, M; Zhang, YH1
Aoki, K; Inoue, K; Kato, N; Kazui, T; Kohara, M; Ohnami, S; Suzuki, K; Yoshida, K; Yoshida, T1
Hirose, H; Iwata, H; Matsuo, H; Mizutani, T; Mori, Y; Nitta, T; Sakamoto, K; Shimamoto, T; Takagi, H; Yamada, T1
George, J1
Lee, ES; Lee, HE; Moon, JO; Shin, JY; Yoon, S1
Li, FH; Liu, C; Liu, CH; Liu, P; Lu, X; Xu, GF1
Cui, X; Fukuno, H; Honda, H; Inoue, H; Ito, S; Itonaga, M; Lu, G; Shimizu, I; Tamaki, K1
Bae, SK; Kim, SG; Lee, I; Lee, JY; Lee, MG; Lee, SJ; Lee, Y1
Cao, L; Liu, SZ; Ming, ZJ1
Hsieh, CC; Lin, WC; Shih, CC; Wu, YW1
Jia, JD; Ma, H; Shen, FJ; Wang, BE; Zhu, YK1
Jia, JD; Ma, H; Shen, FJ; Wang, AM; Wang, BE; Zhu, YK1
Bae, SK; Kim, EJ; Kim, WB; Kwon, JW; Lee, I; Lee, MG1
Wan, MB; Wang, LT; Zhang, B1
Chen, HS; Sha, BX; Shi, JH; Wang, X; Yin, DM; Zhou, YJ1
Hu, YY; Liu, CH; Liu, P; Wang, XN; Zhu, DY1
Liu, P; Lu, X; Wang, L; Zhu, Y1
Jin, JS; Li, CH; Piao, DM; Shen, ZS; Xu, WX; Yin, ZR1
Hasuike, S; Ido, A; Inui, K; Katsura, T; Kim, I; Kodama, M; Kusumoto, K; Moriuchi, A; Nagata, K; Numata, M; Takahama, Y; Tsubouchi, H; Uto, H1
Hu, QW; Liu, GT1
Iwahashi, M; Muragaki, Y; Nakamori, M; Ooshima, A; Ozawa, S; Uchiyama, K; Ueda, K; Ueno, H; Yamaue, H1
Li, FH; Liu, P; Xiong, WG; Xu, GF1
Fujii, K; Gabazza, EC; Hayashi, T; Kishiwada, M; Nishioka, J; Okamoto, T; Suzuki, K; Uemoto, S1
Lee, DY; Lee, I; Lee, MG1
Li, XM; Wang, BE; Wang, TL; Zhao, XY1
Cheng, CC; Chiu, YT; Hsu, YC; Huang, YT; Lin, YL; Wu, CF1
George, J; Tsutsumi, M1
Choy, P; Fan, J; Gong, Y; Li, N; Li, P; Li, X; Shen, H; Siow, Y; Wang, T1
Benedetti, A; Candelaresi, C; Casini, A; Cautero, N; De Minicis, S; di Francesco, F; Marzioni, M; Risaliti, A; Roskams, T; Saccomano, S; Salzano, R; Svegliati-Baroni, G1
Akamatsu, S; Hayashi, S; Isoda, K; Kagaya, N; Kawase, M; Kobayashi, M; Kondoh, M; Tagawa, Y; Tamesada, M; Watanabe, A; Yagi, K1
Chollet, JM; Crougneau, S; Frileux, P; Lautard, M; Perrin, N; Testas, P; Vieillefond, A1
Miyamoto, K1
Benedetti, A; Jezequel, AM; Mancini, R1
Baraona, E; Lieber, CS; Liu, W; Ma, XL; Svegliati-Baroni, G1
Ichida, T; Matsuda, Y; Matsumoto, K; Nakamura, T1
Fujise, N; Higashio, K; Imai, E; Morinaga, T; Shiota, A; Yasuda, H1
Ala-Kokko, L; Ryhanen, L; Savolainen, ER; Stenback, F1
Chandrakasan, G; George, J1
Asakura, H; Ichida, T; Komoriya, Y; Matsuda, Y; Matsumoto, K; Nakamura, T; Nishiyama, E; Yamada, A1
Genina, O; Knopov, V; Lavelin, I; Nagler, A; Pines, M1
Fujise, N; Higashio, K; Masunaga, H; Shiota, A; Yamashita, Y; Yasuda, H1
Fujinaga, T; Kadosawa, T; Miyamoto, T; Mwanza, T; Okumura, M1
Kyotani, S; Miyamura, M; Nishioka, Y; Ono, M1
Fujise, N; Higashio, K; Masunaga, H; Ogawa, H; Shiota, A; Yamashita, Y; Yasuda, H1
Imamura, M; Kaido, T; Seto, S; Yamaoka, S; Yoshikawa, A1
Ii, K; Ito, S; Shiba, M; Shimizu, I; Yasuda, M1
Cho, JJ; Lee, YS1
Horie, T; Ito, S; Liu, F; Ma, YR; Mizobuchi, Y; Shiba, M; Shimizu, I; Yasuda, M1
Hori, H; Ito, S; Mizobuchi, Y; Shimizu, I; Shono, M; Yasuda, M1
Ito, S; Shiba, M; Shimizu, I; Yasuda, M1
Atsuchi, N; Ooshima, A; Qi, Z; Takeshita, A; Ueno, H1
Kin, M; Mitsuyama, K; Nakamura, T; Ogata, R; Sakamoto, M; Sakisaka, S; Sata, M; Sujaku, K; Tamaki, S; Tanikawa, K; Torimura, T; Ueno, T1
Gertman, PM; Madden, JW; Peacock, EE1
Kyotani, S; Miyamura, M; Nishioka, Y; Ohnishi, S; Ono, M; Saibara, T1
Astuchi, N; Nakamura, T; Ohashi, H; Qi, Z; Sakamoto, T; Shimizu, K; Takeshita, A; Ueno, H1
Asakura, H; Ichida, T; Ishikawa, T; Matsuda, Y; Satoh, T; Sugiyama, M; Yonekura, K1
Nakamura, T; Sakata, R; Sata, M; Ueno, H; Ueno, T1
Chandrakasan, G; George, J; Rao, KR; Stern, R1
Chen, W; Hu, Y; Liu, C; Liu, P; Wang, Z1
Auduberteau, H; Calès, P; Lemarie, C; Oberti, F; Veal, N1
Choi, SH; Ha, JR; Kang, KW; Kim, CW; Kim, SG1
Akiyama, M; Fujii, C; Kaneko, S; Kitamura, K; Kobayashi, K; Kondo, T; Mukaida, N; Nakamoto, Y1
Kivirikko, KI; Risteli, J1
Kivirikko, KI; Risteli, J; Tuderman, L1
Levy, M1
Benhanou, M; Bénichou, J; Perrin, N; Testas, P; Vieillefond, A1
Benedetti, A; Jezequel, AM; Mancini, R; Orlandi, F; Paolucci, F; Trozzi, L1
Dobbs, BR; Fraser, R; Rogers, GW1
Ala-Kokko, L; Günzler, V; Hoek, JB; Prockop, DJ; Rubin, E1
Fujiwara, K; Mochida, S; Ogata, I; Tomiya, T1
Jezequel, AM; Mancini, R; Orlandi, F; Paolucci, F; Svegliati Baroni, G1
Ballardini, G; Bianchi, FB; Jezequel, AM; Mancini, R; Orlandi, F; Paolucci, F1
Benedetti, A; Jezequel, AM; Mancini, R; Marucci, L; Orlandi, F; Paolucci, F1
Akasaka, Y1
Baraona, E; Hernández-Muñoz, R; Lieber, CS; Ma, XL1
Ala-Kokko, L; Ryhänen, L; Stenbäck, F2
Braye, S; Fleming, J; Karran, S; McLaren, M; Taylor, I1
Ballardini, G; Bianchi, F; Fallani, M; Jézéquel, AM; Mancini, R; Orlandi, F; Rinaldesi, ML1
Höfer, M; Lee, KS; Lie, TS; Nakajima, Y; Nakano, H; Otani, Y1
Jézéquel, AM; Macarri, G; Mancini, R; Orlandi, F; Rinaldesi, ML; Venturini, C1
Baxter, JN; Day, DW; Devitt, P; Jenkins, SA; Mooney, B; Shields, R; Taylor, I1

Other Studies

121 other study(ies) available for dimethylnitrosamine and Cirrhoses, Experimental Liver

ArticleYear
A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats.
    Archives of toxicology, 2020, Volume: 94, Issue:12

    Topics: Animals; Cell Transformation, Neoplastic; Connexins; Cytokines; Diet, High-Fat; Dimethylnitrosamine; Disease Progression; Gap Junction beta-1 Protein; Inflammation Mediators; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats, Transgenic; Signal Transduction

2020
MiR-34c promotes hepatic stellate cell activation and Liver Fibrogenesis by suppressing ACSL1 expression.
    International journal of medical sciences, 2021, Volume: 18, Issue:3

    Topics: Animals; Coenzyme A Ligases; Collagen; Dimethylnitrosamine; Hepatic Stellate Cells; Humans; Lipid Droplets; Lipid Metabolism; Liver; Liver Cirrhosis, Experimental; MicroRNAs; Rats

2021
Salvianolate Reduces Glucose Metabolism Disorders in Dimethylnitrosamine-Induced Cirrhotic Rats.
    Chinese journal of integrative medicine, 2018, Volume: 24, Issue:9

    Topics: Animals; Dimethylnitrosamine; Glucose; Glucose Tolerance Test; Insulin Resistance; Liver; Liver Cirrhosis, Experimental; Liver Glycogen; Male; Metformin; Plant Extracts; Rats; Rats, Wistar

2018
Experimental Modeling of Alcohol-Induced Liver Cirrhosis in Rats.
    Bulletin of experimental biology and medicine, 2018, Volume: 164, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Animals, Outbred Strains; Aspartate Aminotransferases; Bilirubin; Calcium; Creatinine; Dimethylnitrosamine; Ethanol; gamma-Glutamyltransferase; Liver; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Potassium; Rats; Serum Albumin; Sodium

2018
Protective effect of cultured bear bile powder against dimethylnitrosamine-induced hepatic fibrosis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112

    Topics: Animals; Bile; Cytoprotection; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver Cirrhosis; Liver Cirrhosis, Experimental; Random Allocation; Rats; Rats, Wistar; Ursidae

2019
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
    Toxicology and applied pharmacology, 2019, 05-15, Volume: 371

    Topics: Animals; Autophagy; Cell Line; Cell Proliferation; Common Bile Duct; Dimethylnitrosamine; G1 Phase Cell Cycle Checkpoints; Hepatic Stellate Cells; HSP90 Heat-Shock Proteins; Humans; Ligation; Liver; Liver Cirrhosis, Experimental; Male; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Xanthones

2019
Effect of sinapic acid against dimethylnitrosamine-induced hepatic fibrosis in rats.
    Archives of pharmacal research, 2013, Volume: 36, Issue:5

    Topics: Animals; Biphenyl Compounds; Blotting, Western; Coumaric Acids; Dimethylnitrosamine; Free Radical Scavengers; Lipid Peroxidation; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Molecular Structure; Picrates; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor RelA; Transforming Growth Factor beta1

2013
[Effect of cordyceps polysaccharide on lipid peroxidation of rats with dimethylnitrosamine-induced liver fibrosis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Collagen; Cordyceps; Dimethylnitrosamine; Drug Administration Schedule; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Hydroxyproline; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Phytotherapy; Polysaccharides; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Superoxide Dismutase

2013
[Effects of Corbrin Shugan capsule on dimethylnitrosamine-induced hepatic fibrosis in rats].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2013, Volume: 42, Issue:5

    Topics: Albumins; Animals; Capsules; Collagen Type III; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Laminin; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1

2013
Liposomal oxymatrine in hepatic fibrosis treatment: formulation, in vitro and in vivo assessment.
    AAPS PharmSciTech, 2014, Volume: 15, Issue:3

    Topics: Alkaloids; Animals; Carbon Tetrachloride; Chemistry, Pharmaceutical; Cytoprotection; Dimethylnitrosamine; Drug Carriers; Kinetics; Liposomes; Liver; Liver Cirrhosis, Experimental; Male; Mice, Inbred ICR; Protective Agents; Quinolizines; Solubility; Technology, Pharmaceutical; Vitamin E

2014
Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats.
    Archives of pharmacal research, 2021, Volume: 44, Issue:8

    Topics: Animals; Cypriniformes; Dimethylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Matrix; Hepatic Stellate Cells; Hepatocytes; Liver Cirrhosis, Experimental; Male; Powders; Rats; Rats, Wistar; Transforming Growth Factor beta1

2021
Protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats.
    Food & function, 2015, Volume: 6, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Bile Ducts, Intrahepatic; Biomarkers; Camellia sinensis; Carcinogens; Carcinoma, Hepatocellular; Catechin; Chemical and Drug Induced Liver Injury; Dietary Supplements; Dimethylnitrosamine; Food Handling; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Male; Oxidation-Reduction; Plant Extracts; Plant Leaves; Protective Agents; Random Allocation; Rats, Sprague-Dawley

2015
Comparison of TGF-β, PDGF, and CTGF in hepatic fibrosis models using DMN, CCl4, and TAA.
    Drug and chemical toxicology, 2016, Volume: 39, Issue:1

    Topics: Animals; Carbon Tetrachloride; Connective Tissue Growth Factor; Dimethylnitrosamine; Disease Models, Animal; Immunohistochemistry; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Thioacetamide; Transforming Growth Factor beta

2016
Hepatoprotective effect of juglone on dimethylnitrosamine-induced liver fibrosis and its effect on hepatic antioxidant defence and the expression levels of α-SMA and collagen III.
    Molecular medicine reports, 2015, Volume: 12, Issue:3

    Topics: Actins; Animals; Antioxidants; Collagen Type III; Dimethylnitrosamine; Hepatic Stellate Cells; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Naphthoquinones; PPAR gamma; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2015
A bioinformatic and mechanistic study elicits the antifibrotic effect of ursolic acid through the attenuation of oxidative stress with the involvement of ERK, PI3K/Akt, and p38 MAPK signaling pathways in human hepatic stellate cells and rat liver.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Antioxidants; Cell Line; Cell Proliferation; Collagen Type I; Computational Biology; Dimethylnitrosamine; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 1; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Interaction Maps; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Triterpenes; Ursolic Acid

2015
Reduction of Dimethylnitrosamine-Induced Liver Fibrosis by the Novel Gene Regulator PI Polyamide Targeting Transforming Growth Factor β1 Gene.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:12

    Topics: Actins; Animals; Cell Line; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; End Stage Liver Disease; Fibrosis; Gene Silencing; Hepatic Stellate Cells; Imidazoles; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 2; Pyrroles; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta

2015
Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats.
    Archives of pharmacal research, 2016, Volume: 39, Issue:2

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Dimethylnitrosamine; Guaiacol; Hep G2 Cells; Hepatic Stellate Cells; Humans; Hydroxyproline; Inflammation Mediators; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction

2016
Huangqi decoction alleviates dimethylnitrosamine-induced liver fibrosis: An analysis of bile acids metabolic mechanism.
    Journal of ethnopharmacology, 2016, Aug-02, Volume: 189

    Topics: Animals; Astragalus propinquus; Bile Acids and Salts; Biomarkers; Cell Proliferation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Drugs, Chinese Herbal; Gene Expression Regulation, Enzymologic; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Mass Spectrometry; Metabolomics; Protective Agents; Rats, Wistar; RNA, Messenger

2016
Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation.
    Journal of ethnopharmacology, 2016, Aug-22, Volume: 190

    Topics: Actins; Animals; Astragalus Plant; Cell Line; Cell Survival; Collagen Type I; Common Bile Duct; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation; Glycyrrhizic Acid; Hepatic Stellate Cells; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Male; Mice; Phosphorylation; Phytotherapy; Plants, Medicinal; Protective Agents; Rats, Wistar; RNA, Messenger; Saponins; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1

2016
[Bushen Rougan Recipe in prevention of hepatic fibrosis in rats induced by dimethylnitrosamine: a study on its preliminary mechanism].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2008, Volume: 6, Issue:9

    Topics: Animals; Collagen Type I; Cysteine-Rich Protein 61; Dimethylnitrosamine; Drugs, Chinese Herbal; Liver Cirrhosis, Experimental; Male; Phytotherapy; Random Allocation; Rats; Rats, Wistar; RNA, Messenger

2008
[Cordyceps mycelia extract decreases portal hypertension in rats with dimethylnitrosamine-induced liver cirrhosis: a study on its histological basis].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2008, Volume: 6, Issue:11

    Topics: Animals; Cordyceps; Dimethylnitrosamine; Drugs, Chinese Herbal; Hypertension, Portal; Liver Cirrhosis, Experimental; Portal Vein; Rats; Rats, Wistar

2008
Treating liver cirrhosis in dogs with hepatocyte growth factor gene therapy via the hepatic artery.
    Journal of hepato-biliary-pancreatic surgery, 2009, Volume: 16, Issue:2

    Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Genetic Therapy; Genetic Vectors; Hepatic Artery; Hepatocyte Growth Factor; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Plasmids; Statistics, Nonparametric

2009
[Acting mechanism of Cordyceps mycelia extract for antagonizing hepatic sinusoidal capillarization in rats with dimethylnitrosamine induced liver cirrhosis].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2009, Volume: 29, Issue:9

    Topics: Animals; Capillaries; Cordyceps; Dimethylnitrosamine; Hepatic Veins; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mycelium; Neovascularization, Pathologic; Rats; Rats, Wistar

2009
[Inhibitory effect of anluohuaxianwan on experimental hepatic fibrosis in rats].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2010, Volume: 18, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dimethylnitrosamine; Drug Combinations; Drugs, Chinese Herbal; Hyaluronic Acid; Hydroxyproline; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Matrix Metalloproteinase 2; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley

2010
The protective effect of resveratrol on dimethylnitrosamine-induced liver fibrosis in rats.
    Archives of pharmacal research, 2010, Volume: 33, Issue:4

    Topics: Animals; Antioxidants; Biomarkers; Body Weight; Dimethylnitrosamine; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes

2010
Anti-fibrotic effects of the anthocyanins isolated from the purple-fleshed sweet potato on hepatic fibrosis induced by dimethylnitrosamine administration in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:11

    Topics: Actins; Animals; Anthocyanins; Biomarkers; Body Weight; Chemical Fractionation; Collagen Type I; Collagen Type III; Dimethylnitrosamine; Gene Expression; Ipomoea batatas; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Organ Size; Plant Extracts; Rats; Rats, Sprague-Dawley

2010
[Effect of fuzheng huayu recipe and huangqi tang on DMN-induced experimental liver cirrhosis in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:13

    Topics: Animals; Body Weight; Dimethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Liver; Liver Cirrhosis, Experimental; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2010
[Recipe-syndrome correlation and pathogenesis mechanism of Yinchenhao Decoction in intervening dimethylnitrosamine induced liver cirrhosis progress in rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2010, Volume: 30, Issue:8

    Topics: Animals; Diagnosis, Differential; Dimethylnitrosamine; Drugs, Chinese Herbal; Liver Cirrhosis, Experimental; Male; Medicine, Chinese Traditional; Oxidative Stress; Phytotherapy; Rats; Rats, Wistar

2010
Antifibrotic effects of triptolide on hepatic stellate cells and dimethylnitrosamine-intoxicated rats.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:7

    Topics: Actins; Animals; Cell Line; Collagen; Dimethylnitrosamine; Diterpenes; Epoxy Compounds; Hepatic Stellate Cells; Interleukin-6; Liver; Liver Cirrhosis, Experimental; Male; NF-kappa B; Phenanthrenes; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Tripterygium; Tumor Necrosis Factor-alpha

2011
[Uniform designed research on the active ingredients assembling of huangqi decoction for inhibition of DMN-induced liver fibrosis].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2011, Volume: 31, Issue:10

    Topics: Alanine Transaminase; Animals; Dimethylnitrosamine; Drug Interactions; Drugs, Chinese Herbal; Hydroxyproline; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

2011
Prevention of liver fibrosis and liver reconstitution of DMN-treated rat liver by transplanted EPCs.
    European journal of clinical investigation, 2012, Volume: 42, Issue:7

    Topics: Animals; Biomarkers; Bone Marrow Cells; Cell- and Tissue-Based Therapy; Dimethylnitrosamine; Endothelial Cells; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation

2012
[Real-time elastography for quantitative assessment of liver fibrosis in a rat model].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2012, Volume: 20, Issue:5

    Topics: Animals; Dimethylnitrosamine; Elasticity Imaging Techniques; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

2012
Salvianolic acid B lowers portal pressure in cirrhotic rats and attenuates contraction of rat hepatic stellate cells by inhibiting RhoA signaling pathway.
    Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:12

    Topics: Actins; Animals; Benzofurans; Cardiac Myosins; Cells, Cultured; Dimethylnitrosamine; Endothelin-1; Hepatic Stellate Cells; Histocytochemistry; Liver; Liver Cirrhosis, Experimental; Male; Myosin Light Chains; Phosphorylation; Portal Pressure; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Stress Fibers

2012
[Effects of Chinese herbal medicine Xiaopi Pill in preventing rats from dimethylnitrosamine-induced liver fibrosis].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2012, Volume: 10, Issue:11

    Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

2012
[Formula-syndrome correlation study of three classical anti-jaundice formulas in inhibition of liver fibrosis induced by dimethylnitrosamine in rats].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2012, Volume: 10, Issue:12

    Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Phytotherapy; Rats; Rats, Wistar

2012
Expression of hepatocyte growth factor mRNA in rat liver cirrhosis induced by N-nitrosodimethylamine as evidenced by in situ RT-PCR.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2002, Volume: 50, Issue:11

    Topics: Animals; Dimethylnitrosamine; Hepatocyte Growth Factor; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta

2002
Effect of Sho-saiko-to extract on hepatic inflammation and fibrosis in dimethylnitrosamine induced liver injury rats.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:11

    Topics: Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Inflammation; Liver; Liver Cirrhosis, Experimental; Male; Phytotherapy; Rats; Rats, Wistar

2002
[Suppressive effects of antioxidant DA-9601 on hepatic fibrosis in rats].
    Taehan Kan Hakhoe chi = The Korean journal of hepatology, 2002, Volume: 8, Issue:4

    Topics: Animals; Antioxidants; Artemisia; Dimethylnitrosamine; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Plant Extracts; Rats; Rats, Sprague-Dawley

2002
Tissue remodeling following submassive hemorrhagic necrosis in rat livers induced by an intraperitoneal injection of dimethylnitrosamine.
    Virchows Archiv : an international journal of pathology, 2003, Volume: 442, Issue:1

    Topics: Actins; Animals; Cell Division; Cell Movement; Desmin; Dimethylnitrosamine; Disease Models, Animal; Hemorrhage; Injections, Intraperitoneal; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Necrosis; Rats; Rats, Wistar

2003
Adenovirus-mediated gene transfer of interferon alpha improves dimethylnitrosamine-induced liver cirrhosis in rat model.
    Gene therapy, 2003, Volume: 10, Issue:9

    Topics: Adenoviridae; Animals; Dimethylnitrosamine; Fibrosis; Genetic Therapy; Genetic Vectors; Immunotherapy; Injections, Subcutaneous; Interferon-gamma; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Transduction, Genetic

2003
Experimental studies on morphological changes of microcirculation of DMN-induced liver cirrhosis after normothermic ischemia with charge-coupled device microscope.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:9

    Topics: Animals; Dimethylnitrosamine; Ischemia; Liver; Liver Cirrhosis, Experimental; Male; Microcirculation; Microscopy; Rats; Rats, Wistar; Survival Rate; Time Factors

2003
Ascorbic acid concentrations in dimethylnitrosamine-induced hepatic fibrosis in rats.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 335, Issue:1-2

    Topics: Animals; Ascorbic Acid; Body Weight; Collagen; Dimethylnitrosamine; Lipid Peroxides; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

2003
The flavonoid quercetin inhibits dimethylnitrosamine-induced liver damage in rats.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:8

    Topics: Animals; Dimethylnitrosamine; Liver Cirrhosis, Experimental; Male; Quercetin; Rats; Rats, Sprague-Dawley

2003
[The role of hepatic sinusoid capillarization during the formation of portal hypertension in fibrotic rats induced by dimethylnitrosamine].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2003, Volume: 11, Issue:10

    Topics: Animals; Capillaries; Dimethylnitrosamine; Hypertension, Portal; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

2003
Antioxidant and antiapoptotic activities of idoxifene and estradiol in hepatic fibrosis in rats.
    Life sciences, 2004, Jan-02, Volume: 74, Issue:7

    Topics: Administration, Oral; Animals; Antioxidants; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Dimethylnitrosamine; Disease Models, Animal; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation; Glutathione Peroxidase; Injections, Intraperitoneal; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Superoxide Dismutase; Tamoxifen

2004
Pharmacokinetic changes of oltipraz after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
    International journal of pharmaceutics, 2004, May-04, Volume: 275, Issue:1-2

    Topics: Administration, Oral; Animals; Area Under Curve; Blood Proteins; Dimethylnitrosamine; Injections, Intravenous; Liver Cirrhosis, Experimental; Male; Microsomes, Liver; Protein Binding; Pyrazines; Rats; Rats, Sprague-Dawley; Schistosomicides; Thiones; Thiophenes; Time Factors; Tissue Distribution

2004
[Effect of total glucosides of Centella asiatica on antagonizing liver fibrosis induced by dimethylnitrosamine in rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:8

    Topics: Animals; Centella; Dimethylnitrosamine; Drugs, Chinese Herbal; Female; Glucosides; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Random Allocation; Rats; Rats, Sprague-Dawley

2004
Effect of Anoectochilus formosanus on fibrosis and regeneration of the liver in rats.
    Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:9

    Topics: Animals; Body Weight; Dimethylnitrosamine; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Orchidaceae; Organ Size; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Water

2004
[The effect of angiotensin II type 1 receptor blocker valsartan in preventing hepatic fibrosis induced by dimethylnitrosamine in rats].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2004, Volume: 12, Issue:10

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Dimethylnitrosamine; Female; Liver Cirrhosis, Experimental; Male; Random Allocation; Rats; Rats, Wistar; Tetrazoles; Valine; Valsartan

2004
[Dynamic evolution of MMP-13, TIMP-1, type I and III collagen and their interaction in experimental liver fibrosis].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2004, Volume: 12, Issue:10

    Topics: Animals; Collagen Type I; Collagen Type III; Collagenases; Dimethylnitrosamine; Female; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 13; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2004
Excretion and metabolism of DA-7867, a new oxazolidinone, in rats.
    Biopharmaceutics & drug disposition, 2005, Volume: 26, Issue:2

    Topics: Animals; Anti-Infective Agents; Area Under Curve; Dimethylnitrosamine; Enzyme Inhibitors; Feces; Injections, Intravenous; Liver Cirrhosis, Experimental; Male; Metabolic Clearance Rate; Oxazolidinones; Proadifen; Rats; Rats, Sprague-Dawley; Tail; Time Factors; Tissue Distribution

2005
[Therapeutic effect of Bushen Rougan Recipe on hepatic fibrosis in rats].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2005, Volume: 3, Issue:2

    Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Liver Cirrhosis, Experimental; Male; Phytotherapy; Random Allocation; Rats; Rats, Wistar

2005
Inhibitory effects of idoxifene on hepatic fibrosis in rats.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Cell Proliferation; Cells, Cultured; Collagen Type I; Dimethylnitrosamine; Glutathione Peroxidase; Hepatocytes; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Superoxide Dismutase; Tamoxifen

2005
[Effects of salvianolic acid B on expressions of TGF-beta1 and its receptors in liver of rats with dimethylnitrosamine-induced hepatic fibrosis].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2005, Volume: 3, Issue:4

    Topics: Animals; Benzofurans; Collagen Type I; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Protein Serine-Threonine Kinases; Random Allocation; Rats; Rats, Wistar; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
[The dynamic expression of Thy1.1 positive hepatic oval cells during the shaping and reducing processes of liver cirrhosis induced by dimethylnitrosamine in rats].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2005, Volume: 13, Issue:11

    Topics: Animals; Dimethylnitrosamine; Hepatocytes; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Thy-1 Antigens

2005
Morphological and serum hyaluronic acid, laminin and type IV collagen changes in dimethylnitrosamine-induced hepatic fibrosis of rats.
    World journal of gastroenterology, 2005, Dec-28, Volume: 11, Issue:48

    Topics: Actins; Animals; Collagen Type IV; Dimethylnitrosamine; Hyaluronic Acid; Laminin; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

2005
Repeated intravenous injection of recombinant human hepatocyte growth factor ameliorates liver cirrhosis but causes albuminuria in rats.
    International journal of molecular medicine, 2006, Volume: 17, Issue:3

    Topics: Alanine Transaminase; Albuminuria; Animals; Body Weight; Dimethylnitrosamine; Hepatectomy; Hepatocyte Growth Factor; Humans; Injections, Intravenous; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Organ Size; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serum Albumin

2006
Effects of bicyclol on dimethylnitrosamine-induced liver fibrosis in mice and its mechanism of action.
    Life sciences, 2006, Jul-04, Volume: 79, Issue:6

    Topics: Animals; Biphenyl Compounds; Collagenases; Dimethylnitrosamine; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Mice; Mice, Inbred ICR; Protective Agents; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta

2006
Anti-fibrotic effects of thalidomide on hepatic stellate cells and dimethylnitrosamine-intoxicated rats.
    Journal of biomedical science, 2006, Volume: 13, Issue:3

    Topics: Actins; Animals; Collagen; Dimethylnitrosamine; Fibrosis; I-kappa B Proteins; Immunosuppressive Agents; Liver; Liver Cirrhosis, Experimental; Muscle, Smooth; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Thalidomide; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2006
Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy.
    Surgery, 2006, Volume: 139, Issue:4

    Topics: Adenoviridae; Animals; Combined Modality Therapy; Dimethylnitrosamine; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Hepatectomy; Hepatocyte Growth Factor; Humans; Liver Cirrhosis, Experimental; Protein Serine-Threonine Kinases; Rats; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta

2006
[Effects of Cordyceps sinensis on dimethylnitrosamine-induced liver fibrosis in rats].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2006, Volume: 4, Issue:5

    Topics: Animals; Blotting, Western; Collagen Type I; Collagen Type IV; Cordyceps; Dimethylnitrosamine; Drugs, Chinese Herbal; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 2; Phytotherapy; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-2

2006
Differential regulation of protein S expression in hepatocytes and sinusoidal endothelial cells in rats with cirrhosis.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:12

    Topics: Animals; Cells, Cultured; Dimethylnitrosamine; Endothelial Cells; Fibrin; Gene Expression Regulation; Hepatectomy; Hepatocytes; Interleukin-6; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Male; Polymerase Chain Reaction; Protein S; Rats; Rats, Wistar; Receptors, Interleukin-6; Receptors, Tumor Necrosis Factor, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

2006
Pharmacokinetics of omeprazole after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
    International journal of pharmaceutics, 2007, Feb-07, Volume: 330, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Body Weight; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Dimethylnitrosamine; Injections, Intravenous; Liver Cirrhosis, Experimental; Male; Omeprazole; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley

2007
[Inhibitory effects of silymarin on hepatic fibrosis induced by dimethylnitrosamine: experiment with rats].
    Zhonghua yi xue za zhi, 2006, Sep-26, Volume: 86, Issue:36

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Protective Agents; Random Allocation; Rats; Rats, Wistar; Serum Albumin; Silymarin

2006
Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:1

    Topics: Actins; Alkaloids; Analysis of Variance; Animals; Benzylisoquinolines; Blotting, Western; Cell Line; Dimethylnitrosamine; Fibrosis; Intercellular Adhesion Molecule-1; Liver Cirrhosis, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2007
siRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats.
    Gene therapy, 2007, Volume: 14, Issue:10

    Topics: Actins; Animals; Blotting, Western; Cells, Cultured; Connective Tissue Growth Factor; Dimethylnitrosamine; Fibrosis; Gene Silencing; Genetic Therapy; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Transfection; Transforming Growth Factor beta1

2007
Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2007, Volume: 85, Issue:2

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Collagen Type I; Dimethylnitrosamine; Hepatocytes; Liver Cirrhosis, Experimental; Oleanolic Acid; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Transforming Growth Factor beta1

2007
Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo.
    Gut, 2008, Volume: 57, Issue:3

    Topics: Animals; Cell Proliferation; Cells, Cultured; Chronic Disease; Collagen Type I; Dimethylnitrosamine; Disease Progression; Enkephalin, Methionine; Hepatocytes; Humans; Liver; Liver Cirrhosis, Experimental; Liver Diseases; Male; Opioid Peptides; Paracrine Communication; Rats; Receptors, Opioid; Signal Transduction

2008
Hepatoprotective effect of vitamin B12 on dimethylnitrosamine-induced liver injury.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:2

    Topics: Alanine Transaminase; Alkylating Agents; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Liver Cirrhosis; Liver Cirrhosis, Experimental; Liver Function Tests; Mice; Mice, Inbred BALB C; Reverse Transcriptase Polymerase Chain Reaction; Vitamin B 12; Vitamins

2008
[Dimethylnitrosamine hepatic cirrhosis in the rat (author's transl)].
    Journal de chirurgie, 1981, Volume: 118, Issue:4

    Topics: Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver Cirrhosis, Experimental; Rats

1981
[Experimental study on changes of the pulmonary vessels in the cirrhotic rats].
    Nihon Geka Gakkai zasshi, 1995, Volume: 96, Issue:1

    Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hemodynamics; Hypertension, Pulmonary; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Mononuclear Phagocyte System; Pulmonary Artery; Rats; Rats, Wistar

1995
An interleukin-1 receptor antagonist decreases fibrosis induced by dimethylnitrosamine in rat liver.
    Virchows Archiv : an international journal of pathology, 1994, Volume: 424, Issue:1

    Topics: Actins; Animals; Collagen; Dimethylnitrosamine; Immunoenzyme Techniques; Laminin; Liver; Liver Cirrhosis, Experimental; Male; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1

1994
Acetaldehyde-collagen adducts in N-nitrosodimethylamine-induced liver cirrhosis in rats.
    Life sciences, 1993, Volume: 52, Issue:15

    Topics: Acetaldehyde; Animals; Collagen; Cytosol; Dimethylnitrosamine; Electrophoresis, Polyacrylamide Gel; Liver; Liver Cirrhosis, Experimental; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley

1993
Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats.
    Journal of biochemistry, 1995, Volume: 118, Issue:3

    Topics: Animals; Chronic Disease; Collagenases; Dimethylnitrosamine; Disease Models, Animal; Hepatocyte Growth Factor; Liver Cirrhosis, Experimental; Liver Failure; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins

1995
Antifibrogenic effect of a deletion variant of hepatocyte growth factor on liver fibrosis in rats.
    Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:3

    Topics: Actins; Animals; Collagen; Desmin; Dimethylnitrosamine; Gene Deletion; Genetic Variation; Hepatocyte Growth Factor; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Muscle, Smooth; Organ Size; Procollagen; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta

1996
The effect of malotilate on type III and type IV collagen, laminin and fibronectin metabolism in dimethylnitrosamine-induced liver fibrosis in the rat.
    Journal of hepatology, 1996, Volume: 24, Issue:2

    Topics: Animals; Antibody Specificity; Collagen; Dimethylnitrosamine; Evaluation Studies as Topic; Extracellular Matrix; Female; Fibronectins; Immunoenzyme Techniques; Laminin; Liver Cirrhosis, Experimental; Malonates; Rats; Rats, Sprague-Dawley

1996
Glycoprotein metabolism in dimethylnitrosamine induced hepatic fibrosis in rats.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:3

    Topics: Animals; Collagen; Dimethylnitrosamine; Glycoproteins; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Statistics as Topic

1996
Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Dimethylnitrosamine; Fibrinogen; Hepatocyte Growth Factor; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serum Albumin; Survival Rate

1997
Halofuginone, a specific inhibitor of collagen type I synthesis, prevents dimethylnitrosamine-induced liver cirrhosis.
    Journal of hepatology, 1997, Volume: 27, Issue:2

    Topics: Alkaline Phosphatase; Animals; Collagen; Dimethylnitrosamine; Gene Expression; In Situ Hybridization; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Male; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley

1997
Deleted form of hepatocyte growth factor (dHGF) increases the number of platelets in rats with liver cirrhosis.
    Liver, 1997, Volume: 17, Issue:4

    Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hepatocyte Growth Factor; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Platelet Count; Prothrombin Time; Rats; Rats, Wistar; Spleen; Thrombocytopenia

1997
Ultrasonography, biochemical and hematological profiles in liver disease caused by intravenous administration of dimethylnitrosamine in dogs.
    The Japanese journal of veterinary research, 1997, Volume: 45, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carcinogens; Dimethylnitrosamine; Dog Diseases; Dogs; Female; Gallbladder; gamma-Glutamyltransferase; Globulins; Injections, Intravenous; Liver; Liver Cirrhosis, Experimental; Liver Diseases; Male; Ultrasonography

1997
Effects of sho-saiko-to extract on fibrosis and regeneration of the liver in rats.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dimethylnitrosamine; Drugs, Chinese Herbal; Hepatectomy; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Rats; Rats, Wistar; Retinoids; Spleen

1998
Effects of the deleted form of hepatocyte growth factor on serum hyaluronate levels in rats with liver cirrhosis.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:3

    Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hepatocyte Growth Factor; Humans; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Organ Size; Prothrombin Time; Rats; Rats, Wistar; Recombinant Proteins; Sequence Deletion

1998
Perioperative continuous hepatocyte growth factor supply prevents postoperative liver failure in rats with liver cirrhosis.
    The Journal of surgical research, 1998, Feb-01, Volume: 74, Issue:2

    Topics: Animals; Blood Chemical Analysis; Cell Division; Dimethylnitrosamine; Fibroblasts; Gene Expression; Hepatectomy; Hepatocyte Growth Factor; Liver; Liver Cirrhosis, Experimental; Liver Failure; Liver Regeneration; Male; Rats; Rats, Inbred F344; Spleen; Survival Rate; Transfection

1998
Expression of type I and type III collagens during the course of dimethylnitrosamine-induced hepatic fibrosis in rats.
    Liver, 1998, Volume: 18, Issue:3

    Topics: Animals; Blotting, Northern; Collagen; Dimethylnitrosamine; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

1998
Enzyme-linked immunosorbent assay for serum procollagen type III peptide in rats with hepatic fibrosis.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:11

    Topics: Animals; Bile Ducts; Biomarkers; Dimethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Peptide Fragments; Procollagen; Rats; Rats, Sprague-Dawley

1998
Inhibitory effect of oestradiol on activation of rat hepatic stellate cells in vivo and in vitro.
    Gut, 1999, Volume: 44, Issue:1

    Topics: Animals; Blotting, Northern; Cell Culture Techniques; Collagen; Dimethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Estradiol; Immunoenzyme Techniques; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar

1999
Retinyl palmitate reduces hepatic fibrosis in rats induced by dimethylnitrosamine or pig serum.
    Journal of hepatology, 1998, Volume: 29, Issue:6

    Topics: Animals; Antioxidants; Blood Physiological Phenomena; Dimethylnitrosamine; Diterpenes; Dose-Response Relationship, Drug; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Retinyl Esters; Swine; Vitamin A

1998
Suppressive effects of estradiol on dimethylnitrosamine-induced fibrosis of the liver in rats.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:3

    Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Dimethylnitrosamine; Estradiol; Female; Fibroblasts; Liver; Liver Cirrhosis, Experimental; Male; Muscle, Smooth; Rats; Rats, Wistar; Sex Characteristics

1999
Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5

    Topics: Adenoviridae; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Dimethylnitrosamine; Genetic Therapy; Genetic Vectors; Hyaluronic Acid; Liver; Liver Cirrhosis, Experimental; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Signal Transduction; Survival Rate; Transforming Growth Factor beta

1999
OK-432 treatment increases matrix metalloproteinase-9 production and improves dimethylnitrosamine-induced liver cirrhosis in rats.
    International journal of molecular medicine, 1999, Volume: 3, Issue:5

    Topics: Actins; Animals; Collagen; Collagenases; Dimethylnitrosamine; Hyaluronic Acid; Immunohistochemistry; Immunologic Factors; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 9; Picibanil; Rats; Rats, Wistar; RNA, Messenger

1999
Dimethylnitrosamine-induced hepatic cirrhosis: a new canine model of an ancient human disease.
    Surgery, 1970, Volume: 68, Issue:1

    Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Dogs; Female; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Lymphatic System; Male; Portal System

1970
Effects of Sho-saiko-to extract on liver fibrosis in relation to the changes in hydroxyproline and retinoid levels of the liver in rats.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:9

    Topics: Administration, Oral; Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hydroxyproline; Hypolipidemic Agents; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Retinoids

1999
A soluble transforming growth factor beta receptor expressed in muscle prevents liver fibrogenesis and dysfunction in rats.
    Human gene therapy, 2000, Jan-01, Volume: 11, Issue:1

    Topics: Animals; Dimethylnitrosamine; Genetic Therapy; Injections, Intramuscular; Liver; Liver Cirrhosis, Experimental; Muscle, Skeletal; Rats; Receptors, Transforming Growth Factor beta; Signal Transduction

2000
Interaction between hyaluronan and CD44 in the development of dimethylnitrosamine-induced liver cirrhosis.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:4

    Topics: Animals; Biomarkers; Blotting, Northern; Dimethylnitrosamine; DNA Probes; Endothelium, Vascular; Hyaluronan Receptors; Hyaluronic Acid; Intercellular Adhesion Molecule-1; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Lymphocytes; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; von Willebrand Factor

2000
Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:2

    Topics: Animals; Dimethylnitrosamine; Extracellular Matrix Proteins; Hepatocyte Growth Factor; Immunohistochemistry; Interferon-gamma; Ki-67 Antigen; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta

2000
Dimethylnitrosamine-induced liver injury in rats: the early deposition of collagen.
    Toxicology, 2001, Jan-02, Volume: 156, Issue:2-3

    Topics: Animals; Apoptosis; Behavior, Animal; Body Weight; Collagen; Dimethylnitrosamine; DNA; Eating; Hemorrhage; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Organ Size; Proteins; Rats; Rats, Wistar; Survival Rate

2001
[Changes of lipid peroxidation in liver fibrogenesis induced by dimethylnitrosamine and drugs' intervention].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2001, Volume: 9 Suppl

    Topics: Animals; Dimethylnitrosamine; Hydroxyproline; Interferon-gamma; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Superoxide Dismutase

2001
Effects of octreotide on intestinal transit and bacterial translocation in conscious rats with portal hypertension and liver fibrosis.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:11

    Topics: Animals; Bacterial Translocation; Consciousness; Dimethylnitrosamine; Gastrointestinal Transit; Hormones; Hypertension, Portal; Liver Cirrhosis, Experimental; Octreotide; Random Allocation; Rats; Rats, Sprague-Dawley

2001
Inhibition of dimethylnitrosamine-induced liver fibrosis by [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) in rats: suppression of transforming growth factor-beta1 and tumor necrosis factor-alpha expression.
    Chemico-biological interactions, 2002, Jan-22, Volume: 139, Issue:1

    Topics: Animals; Base Sequence; Dimethylnitrosamine; DNA Primers; Glyceraldehyde-3-Phosphate Dehydrogenases; Liver Cirrhosis, Experimental; Pyrazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiones; Thiophenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2002
Pathogenic roles of tumor necrosis factor receptor p55-mediated signals in dimethylnitrosamine-induced murine liver fibrosis.
    Laboratory investigation; a journal of technical methods and pathology, 2002, Volume: 82, Issue:5

    Topics: Animals; Antigens, CD; Chemokine CCL2; Collagen; Dimethylnitrosamine; DNA Primers; Female; Gene Expression; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Matrix Metalloproteinases; Mice; Mice, Inbred BALB C; Mice, Knockout; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Specific Pathogen-Free Organisms; Tissue Inhibitor of Metalloproteinases; Tumor Necrosis Factor-alpha

2002
Intracellular enzymes of collagen biosynthesis in rat liver as a function of age and in hepatic injury induced by dimethylnitrosamine. Changes in prolyl hydroxylase, lysyl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase activi
    The Biochemical journal, 1976, Aug-15, Volume: 158, Issue:2

    Topics: Age Factors; Animals; Collagen; Dimethylnitrosamine; Female; Galactosyltransferases; Glucosyltransferases; Liver; Liver Cirrhosis, Experimental; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Procollagen-Proline Dioxygenase; Rats; Time Factors

1976
Intracellular enzymes of collagen biosynthesis in rat liver as a function of age and in hepatic injury induced by dimethylnitrosamine. Purification of rat prolyl hydroxylase and comparison of changes in prolyl hydroxylase activity with changes in immunore
    The Biochemical journal, 1976, Aug-15, Volume: 158, Issue:2

    Topics: Age Factors; Animals; Chromatography, Affinity; Collagen; Dimethylnitrosamine; Female; Liver; Liver Cirrhosis, Experimental; Molecular Weight; Procollagen-Proline Dioxygenase; Radioimmunoassay; Rats

1976
Sodium retention and ascites formation in dogs with experimental portal cirrhosis.
    The American journal of physiology, 1977, Volume: 233, Issue:6

    Topics: Animals; Ascites; Blood Volume; Central Venous Pressure; Denervation; Dimethylnitrosamine; Dogs; Kidney; Kidney Tubules; Liver Cirrhosis, Experimental; Natriuresis; Portal System; Sodium; Venous Pressure; Water-Electrolyte Balance

1977
Comparative study of two models for experimental cirrhosis in the dog.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1978, Volume: 10, Issue:2

    Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Dogs; Hepatic Veins; Ligation; Liver Cirrhosis, Experimental; Models, Biological; Nitrosamines

1978
Quantitative analysis of proliferating sinusoidal cells in dimethylnitrosamine-induced cirrhosis. An immunohistochemical study.
    Journal of hepatology, 1992, Volume: 15, Issue:3

    Topics: Animals; Bromodeoxyuridine; Desmin; Dimethylnitrosamine; Disease Models, Animal; Immunohistochemistry; Intermediate Filaments; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; S Phase

1992
Decreased hepatic uptake of cholesterol and retinol in the dimethylnitrosamine rat model of cirrhosis.
    Liver, 1992, Volume: 12, Issue:5

    Topics: Animals; Cholesterol; Chylomicrons; Dimethylnitrosamine; Disease Models, Animal; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Tritium; Vitamin A

1992
Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:1

    Topics: Animals; Biomarkers; Carbon Tetrachloride Poisoning; Collagen; Dimethylnitrosamine; Female; Fibrosis; Hydroxyproline; Immunoassay; Inflammation; Liver; Liver Cirrhosis, Experimental; Macromolecular Substances; Peptide Fragments; Procollagen; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger

1992
Minor contribution of hepatocytes to collagen production in normal and early fibrotic rat livers.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:2

    Topics: Amino Acids; Animals; Carbon Tetrachloride; Collagen; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Protein Biosynthesis; Rats; Rats, Inbred F344; Reference Values; Serum Albumin; Time Factors

1991
Phenotypic analysis of inflammatory infiltrate in rats with dimethylnitrosamine-induced cirrhosis.
    International journal of experimental pathology, 1991, Volume: 72, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Dimethylnitrosamine; Immunoenzyme Techniques; Immunophenotyping; Liver; Liver Cirrhosis, Experimental; Lymphocyte Subsets; Rats; Rats, Inbred Strains

1991
Modulation of extracellular matrix components during dimethylnitrosamine-induced cirrhosis.
    Journal of hepatology, 1990, Volume: 11, Issue:2

    Topics: Actins; Animals; Collagen; Desmin; Dimethylnitrosamine; Extracellular Matrix; Fibronectins; Heparitin Sulfate; Immunohistochemistry; Injections, Intraperitoneal; Laminin; Liver; Liver Cirrhosis, Experimental; Male; Microscopy, Electron; Rats; Rats, Inbred Strains

1990
Immunohistochemical identification of proliferating cells following dimethylnitrosamine-induced liver injury.
    Liver, 1990, Volume: 10, Issue:5

    Topics: Animals; Dimethylnitrosamine; Immunoenzyme Techniques; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Rats; Rats, Inbred Strains; S Phase

1990
[Experimental studies on extension of resectability of the liver in dogs with special reference to an extended hepatectomy in two stages after ligation of the portal vein branch].
    Nihon Geka Gakkai zasshi, 1990, Volume: 91, Issue:6

    Topics: Animals; Dimethylnitrosamine; Dogs; Female; Hepatectomy; Ligation; Liver Cirrhosis, Experimental; Male; Portal Vein

1990
High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration.
    Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:6

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Carbon Tetrachloride; Dimethylnitrosamine; Ethanol; Fatty Liver; Glycine Hydroxymethyltransferase; Liver; Liver Cirrhosis, Experimental; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Threonine; Threonine Dehydratase

1989
Morphological, immunohistochemical and ultrastructural changes in dimethylnitrosamine [correction of dimenthylnitrosamine] induced liver injury. Effect of malotilate.
    Histology and histopathology, 1989, Volume: 4, Issue:1

    Topics: Animals; Basement Membrane; Chemical and Drug Induced Liver Injury; Collagen; Dimethylnitrosamine; Female; Immunoenzyme Techniques; Immunohistochemistry; Laminin; Liver; Liver Cirrhosis, Experimental; Malonates; Microscopy, Electron; Rats; Rats, Inbred Strains

1989
Changes in blood flow, portal pressure and shunting during the development of cirrhosis in response to beta-blockade.
    Gut, 1987, Volume: 28, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Carbon Tetrachloride; Dimethylnitrosamine; Liver; Liver Cirrhosis, Experimental; Male; Portal Vein; Rats; Rats, Inbred Strains; Regional Blood Flow; Venous Pressure

1987
Preventive effect of malotilate on dimethylnitrosamine-induced liver fibrosis in the rat.
    The Journal of laboratory and clinical medicine, 1989, Volume: 113, Issue:2

    Topics: Animals; Collagen; Dimethylnitrosamine; Female; Liver; Liver Cirrhosis, Experimental; Macrophages; Malonates; Procollagen; Rats; Rats, Inbred Strains; RNA, Messenger

1989
Dimethylnitrosamine-induced cirrhosis. Evidence for an immunological mechanism.
    Journal of hepatology, 1989, Volume: 8, Issue:1

    Topics: Animals; Biomechanical Phenomena; Desmin; Dimethylnitrosamine; Histocompatibility Antigens Class II; Immunohistochemistry; Liver Cirrhosis, Experimental; Macrophages; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Vimentin

1989
Alteration of thymus and of immune regulatory-antifibroblast factors in acute and chronic hepatic damage.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1987, Volume: 187, Issue:3

    Topics: Acute Disease; Animals; Carbon Tetrachloride; Cell Count; Cell Division; Chronic Disease; Dimethylnitrosamine; Fibroblasts; Liver Cirrhosis, Experimental; Liver Extracts; Lymphocyte Culture Test, Mixed; Male; Rats; Rats, Inbred Lew; Rats, Inbred Strains; T-Lymphocytes; Thymus Gland

1987
A morphological study of the early stages of hepatic fibrosis induced by low doses of dimethylnitrosamine in the rat.
    Journal of hepatology, 1987, Volume: 5, Issue:2

    Topics: Animals; Collagen; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver; Liver Cirrhosis, Experimental; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Time Factors

1987
The effects of vasopressin on hepatic haemodynamics in the cirrhotic and non-cirrhotic rat.
    Langenbecks Archiv fur Chirurgie, 1985, Volume: 365, Issue:2

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver Circulation; Liver Cirrhosis, Experimental; Male; Portal Vein; Rats; Rats, Inbred Strains; Vasopressins

1985