Page last updated: 2024-08-17

dimethylnitrosamine and Cell Transformation, Neoplastic

dimethylnitrosamine has been researched along with Cell Transformation, Neoplastic in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199029 (49.15)18.7374
1990's10 (16.95)18.2507
2000's8 (13.56)29.6817
2010's8 (13.56)24.3611
2020's4 (6.78)2.80

Authors

AuthorsStudies
Liu, Q; Liu, R; Lu, Q; Pu, Y; Wang, S; Yin, L; Yu, X; Zhang, H; Zhang, Y; Zhao, C; Zhou, J1
Chen, X; Dong, CD; Jiang, Y; Liu, K; Liu, Z; Ren, Y; Wu, Q; Xie, Y; Yao, K; Yuan, Q; Zhang, J; Zhao, J; Zhao, S1
Chen, T; Cui, L; Li, L; Li, Z; Qiao, T; Sun, C; Wu, K; Xu, F1
Aoyama, Y; Inaguma, S; Kato, H; Nagayasu, Y; Naiki, T; Naiki-Ito, A; Suzuki, S; Takahashi, S; Yeewa, R1
Bae, YM; Choi, MH; Hong, ST; Kim, EM1
Aleksandrov, VA; Bespalov, VG1
Agorreta, J; Ajona, D; Blanco, D; Bleau, AM; de Biurrun, G; Freire, J; Guruceaga, E; Montuenga, LM; Pio, R; Segura, V1
Boonjaruspinyo, S; Boonmars, T; Juasook, A; Kaewsamut, B; Nagano, I; Pinlaor, S; Puapairoj, A; Srisawangwong, T; Sudsarn, P; Wonkchalee, O; Wu, Z; Yongvanit, P1
Bhudhisawasdi, V; Boonjaraspinyo, S; Boonmars, T; Kaewkes, S; Loilome, W; Nagano, I; Sithithaworn, P; Takahashi, Y; Wu, Z; Yongvanit, P1
Chen, X; Jia, X; Li, N; Yang, CS; Yang, H1
Aukkanimart, R; Boonmars, T; Juasook, A; Loilome, W; Namwat, N; Sriraj, P; Sudsarn, P; Veteewuthacharn, K; Wonkchalee, O; Wu, Z1
Feith, DJ; Fong, LY; Pegg, AE1
Chen, T; Stoner, GD1
Devi, BJ; Schneeweiss, FH; Sharan, RN1
Furukawa, Y; Ishii, H; Mimori, K; Mori, M; Vecchione, A; Yoshikawa, Y1
Alder, H; Baffa, R; Baldassarre, G; Battista, S; Belletti, B; Croce, CM; Donovan, PJ; Farber, JL; Fong, LY; Guarnieri, D; Ishii, H; Nicoloso, MS; Petrocca, F; Vecchione, A; Zanesi, N1
Aqeilan, HA; Aqeilan, RI; Croce, CM; Fong, LY; Hagan, JP; Pichiorri, F1
Banfalvi, G; Dombradi, Z; Gacsi, M; Kertai, P; Nagy, G; Somogyi, C; Trencsényi, G1
Breen, PA; Sivak, A; Tu, AS1
Hard, GC; Inoue, K; Mackay, RL; Martin, JT1
Jiao, BZ1
Ockey, CH; Swindell, JA1
Clarke, FM; Hard, GC; Toh, BH1
Glick, MC; Hard, GC; Rachesky, MH1
Babcock, MS; Cothern, GA; Gunning, WT; Klaunig, JE; Knipe, SM; Stoner, GD1
Montesano, R1
Brown, C; Hard, GC; King, H1
Tsuchiya, T; Umeda, M1
Cui, X; Li, H; Lu, S1
Asamoto, M; Iwase, T; Kato, T; Matsumoto, K; Montesano, R; Nagao, S; Ozaki, K; Tsuda, H; Wild, CP1
Earnest, DL; Eskelson, CD; Mufti, SI; Odeleye, OE; Watson, RR1
Bijur, GN; Robertson, FM; Sabourin, CL; Stoner, GD; Wang, QS1
Asakura, S; Daimon, H; Sagami, F; Sawada, S1
Anderson, LM; Bialkowska, A; Birely, L; Diwan, BA; Fornwald, LW; Perella, C; Ramakrishna, G; Shiao, YH1
Huberman, E; Sachs, L; Traut, M1
Farber, JL; Fong, LY; Nguyen, VT1
Roane, PR1
Katahira, S; Konno, K; Minami, K; Yokota, T1
Hard, GC1
Cauchi, MN; Hard, GC; Muller, HK; Toh, BH1
Borland, R; Hard, GC1
Hard, GC; Stewart, BW1
Borland, R; Hard, GC; King, H; Stewart, BW1
Cameron, R; Farber, E; Laishes, B; Medline, A; Ogawa, K; Solt, D1
Farber, E; Gruenstein, M; Parker, S1
Mondal, S1
Drevon, C; Montesano, R; Saint Vincent, L; Tomatis, L1
Golub, NI; Kolesnichenko, TS; Shabad, LM1
Buehler, R; Moolten, F1
Choie, DD; Forger, JM; Friedberg, EC1
Sugihara, R; Sugihara, S1
Kaufman, DG; Kaufmann, WK; Zhang, Y1
Ahotupa, M; Bartsch, H; Bereziat, JC; Cabral, JR; Camus, AM; Hietanen, E; Laitinen, M1
Kouri, RE; Lubet, RA; McCarvill, JT; Putman, DL; Schechtman, LM1
Anderson, MW; Reynolds, SH; Stoner, GD; Wang, Y; You, M1
Archer, MC; Brown, K; Hirani-Hojatti, S; Kovnat, A; Milligan, JR1
Dolan, M; Fausto, N; Goyette, M; Kaufman, D; Kaufmann, W; Shank, PR1
Kiss, E; Kouri, RE; Lubet, RA; McCarvill, J; Nims, R; Schechtman, LM1
Hard, GC; Magee, PN; Shore, SK1

Other Studies

59 other study(ies) available for dimethylnitrosamine and Cell Transformation, Neoplastic

ArticleYear
Metabolomic transition trajectory and potential mechanisms of N-nitrosomethylbenzylamine induced esophageal squamous cell carcinoma in rats.
    Ecotoxicology and environmental safety, 2022, Oct-01, Volume: 244

    Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Dimethylnitrosamine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Metabolome; NAD; Niacin; Niacinamide; Nitrogen; Nitrosamines; Rats; Sphingolipids; Tryptophan; Tumor Microenvironment

2022
Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer.
    Molecular carcinogenesis, 2020, Volume: 59, Issue:2

    Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dimethylnitrosamine; Down-Regulation; Esophageal Neoplasms; Humans; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Precancerous Conditions; Signal Transduction

2020
Anticancer effects and possible mechanisms of lycopene intervention on N-methylbenzylnitrosamine induced esophageal cancer in F344 rats based on PPARγ
    European journal of pharmacology, 2020, Aug-15, Volume: 881

    Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Esophagus; Inflammation Mediators; Lycopene; Male; NF-kappa B; Oxidative Stress; PPAR gamma; Rats, Inbred F344; Signal Transduction

2020
A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats.
    Archives of toxicology, 2020, Volume: 94, Issue:12

    Topics: Animals; Cell Transformation, Neoplastic; Connexins; Cytokines; Diet, High-Fat; Dimethylnitrosamine; Disease Progression; Gap Junction beta-1 Protein; Inflammation Mediators; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats, Transgenic; Signal Transduction

2020
Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine.
    PLoS neglected tropical diseases, 2019, Volume: 13, Issue:4

    Topics: Animals; Carcinogenesis; Carcinogens; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cholangiocarcinoma; Clonorchis sinensis; Connexin 43; Connexins; Dimethylnitrosamine; Epithelial Cells; Gene Silencing; Helminth Proteins; Humans

2019
[Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors].
    Voprosy onkologii, 2012, Volume: 58, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Calcium Compounds; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Female; Glucaric Acid; Glucuronic Acid; Mice; Potassium Compounds; Salts; Uterine Cervical Neoplasms

2012
Silica-induced chronic inflammation promotes lung carcinogenesis in the context of an immunosuppressive microenvironment.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:8

    Topics: AMP-Activated Protein Kinases; Animals; Cell Transformation, Neoplastic; Cellular Microenvironment; Chronic Disease; Cytokines; Dimethylnitrosamine; Female; Immunohistochemistry; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mutation; Oligonucleotide Array Sequence Analysis; Pneumonia; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins p21(ras); Silicon Dioxide; Transcriptome; Tumor Suppressor Protein p53

2013
Involvement of c-Ski oncoprotein in carcinogenesis of cholangiocacinoma induced by Opisthorchis viverrini and N-nitrosodimethylamine.
    Pathology oncology research : POR, 2011, Volume: 17, Issue:2

    Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinogens; Cell Transformation, Neoplastic; Cholangiocarcinoma; Cricetinae; Dimethylnitrosamine; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mesocricetus; Opisthorchiasis; Opisthorchis; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; Smad4 Protein; Transforming Growth Factor beta

2011
Overexpression of PDGFA and its receptor during carcinogenesis of Opisthorchis viverrini-associated cholangiocarcinoma.
    Parasitology international, 2012, Volume: 61, Issue:1

    Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Transformation, Neoplastic; Cholangiocarcinoma; Cricetinae; Dimethylnitrosamine; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mesocricetus; Opisthorchiasis; Opisthorchis; Platelet-Derived Growth Factor; Real-Time Polymerase Chain Reaction; Receptor, Platelet-Derived Growth Factor alpha; Reverse Transcriptase Polymerase Chain Reaction; Rodent Diseases; Thailand

2012
Time-selective chemoprevention of vitamin E and selenium on esophageal carcinogenesis in rats: the possible role of nuclear factor kappaB signaling pathway.
    International journal of cancer, 2012, Oct-01, Volume: 131, Issue:7

    Topics: Amino Acids; Animals; Biomarkers; Cell Proliferation; Cell Transformation, Neoplastic; Dietary Supplements; Dimethylnitrosamine; Esophageal Neoplasms; Inflammation; Male; NF-kappa B; Nutritional Status; Rats; Rats, Inbred F344; Selenium; Signal Transduction; Time Factors; Vitamin E

2012
Immunosuppressive prednisolone enhances early cholangiocarcinoma in Syrian hamsters with liver fluke infection and administration of N-nitrosodimethylamine.
    Pathology oncology research : POR, 2013, Volume: 19, Issue:1

    Topics: Animals; Bile Duct Neoplasms; Cell Transformation, Neoplastic; Cholangiocarcinoma; Chronic Disease; Cocarcinogenesis; Cricetinae; Cyclooxygenase 2; Dimethylnitrosamine; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Liver; Liver Cirrhosis; Liver Neoplasms; Mesocricetus; Opisthorchiasis; Prednisolone

2013
Targeted expression of ornithine decarboxylase antizyme prevents upper aerodigestive tract carcinogenesis in p53-deficient mice.
    Carcinogenesis, 2013, Volume: 34, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Gastric Mucosa; Head and Neck Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Polyamines; Proteins; Quinolones; Tongue Neoplasms; Tumor Burden; Tumor Suppressor Protein p53

2013
Inducible nitric oxide synthase expression in N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis.
    Molecular carcinogenesis, 2004, Volume: 40, Issue:4

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Immunohistochemistry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Reverse Transcriptase Polymerase Chain Reaction

2004
Negative correlation between poly-ADP-ribosylation of spleen cell histone proteins and initial duration of dimethylnitrosamine exposure to mice in vivo measured by Western blot immunoprobe assay: a possible biomarker for cancer detection.
    Cancer detection and prevention, 2005, Volume: 29, Issue:1

    Topics: Animals; Biomarkers, Tumor; Blotting, Western; Cell Transformation, Neoplastic; Dimethylnitrosamine; Histones; Immunoassay; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Poly Adenosine Diphosphate Ribose; Proteins; Sensitivity and Specificity; Spleen

2005
Differential roles of E-type cyclins during transformation of murine E2F-1-deficient cells.
    DNA and cell biology, 2005, Volume: 24, Issue:3

    Topics: Animals; Cell Cycle Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cyclins; Dimethylnitrosamine; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Fibroblasts; Mice; Mice, Mutant Strains; Stomach Neoplasms; Transcription Factors

2005
Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.
    Cancer cell, 2007, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinogens; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Segregation; Dimethylnitrosamine; Fibroblasts; Mice; Mice, Knockout; Mitosis; Molecular Sequence Data; Nocodazole; Paclitaxel; Stomach Neoplasms; Tumor Suppressor Proteins

2007
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
    Cancer research, 2007, Jun-15, Volume: 67, Issue:12

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Disease Progression; Esophageal Neoplasms; Gene Silencing; Genetic Predisposition to Disease; Immunohistochemistry; Mice; Neoplasms, Squamous Cell; Oxidoreductases; Stomach Neoplasms; WW Domain-Containing Oxidoreductase

2007
Chemically induced carcinogenesis affecting chromatin structure in rat hepatocarcinoma cells.
    DNA and cell biology, 2007, Volume: 26, Issue:9

    Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transformation, Neoplastic; Chromatin; Dimethylnitrosamine; Hepatocytes; Liver Neoplasms; Male; Nitrosamines; Rats; Rats, Inbred F344; Rats, Long-Evans; Tumor Cells, Cultured

2007
Comparison of primary hepatocytes and S9 metabolic activation systems for the C3H-10T 1/2 cell transformation assay.
    Carcinogenesis, 1984, Volume: 5, Issue:11

    Topics: Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cyclophosphamide; Dimethylnitrosamine; In Vitro Techniques; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C3H; Microsomes, Liver; Rats; Rats, Inbred F344; Rats, Inbred Strains

1984
Differentiated features of a transformed epithelial cell line (TRKE-1) derived from dimethylnitrosamine-treated rat kidney.
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dimethylnitrosamine; Epithelium; Kidney; Kinetics; Microscopy, Electron; Rats

1983
[Studies on canceration of esophageal epithelium--(SEM) and (TEM) observations].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1983, Volume: 5, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Esophagus; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Neoplasms, Experimental; Nitrosamines

1983
Cytogenetic changes during the early stages of liver carcinogenesis in Chinese hamster: an in vivo--in vitro comparison.
    Cancer genetics and cytogenetics, 1983, Volume: 10, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Cricetinae; Cricetulus; Dimethylnitrosamine; Karyotyping; Liver; Liver Neoplasms; Male; Metaphase; Neoplasms, Experimental

1983
Comparison of polypeptide profiles in normal and transformed kidney cell lines derived from control, dimethylnitrosamine-treated, and renal tumor-bearing rats, with particular reference to contractile proteins.
    Cancer research, 1980, Volume: 40, Issue:10

    Topics: Actins; Animals; Calmodulin; Cell Line; Cell Transformation, Neoplastic; Contractile Proteins; Dimethylnitrosamine; Electrophoresis, Polyacrylamide Gel; Fibronectins; Kidney Neoplasms; Myosins; Peptides; Rats

1980
Membrane glycopeptides from chemically transformed cells: comparison between mesenchymal and epithelial cell lines derived from dimethylnitrosamine-treated rat kidney.
    Cancer research, 1982, Volume: 42, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Glycopeptides; Kidney Neoplasms; Membrane Proteins; Mesoderm; Neoplasm Proteins; Neoplasms, Experimental; Rats

1982
In vitro transformation of rat esophageal epithelial cells with N-nitrosobenzylmethylamine.
    Carcinogenesis, 1982, Volume: 3, Issue:6

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophagus; Male; Rats; Rats, Inbred F344

1982
Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis.
    Journal of supramolecular structure and cellular biochemistry, 1981, Volume: 17, Issue:3

    Topics: Alkylation; Animals; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA; DNA Repair; Liver; Liver Neoplasms; Mesocricetus; Methylation; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Rats; Structure-Activity Relationship

1981
Isolation of a morphologically-transformed epithelial cell-line from rat kidney following an in vivo dose of dimethylnitrosamine.
    Cancer letters, 1980, Volume: 10, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Female; Kidney; Rats

1980
Improvement in the efficiency of the in vitro transformation assay method using BALB/3T3 A31-1-1 cells.
    Carcinogenesis, 1995, Volume: 16, Issue:8

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Culture Media; Dimethylnitrosamine; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate

1995
[Multiple tumor suppressor genes in esophageal carcinoma induced in human fetus esophageal epithelium by NMBzA].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1995, Volume: 17, Issue:3

    Topics: Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Fetus; Gene Deletion; Genes, Tumor Suppressor; Humans; Point Mutation

1995
Decreased dimethylnitrosamine-induced O6- and N7-methyldeoxyguanosine levels correlate with development and progression of lesions in rat hepatocarcinogenesis.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344

1993
Modulation of cancer growth by vitamin E and alcohol.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1993, Volume: 28, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimethylnitrosamine; Esophageal Neoplasms; Female; Mice; Mice, Inbred C57BL; Vitamin E

1993
Alterations in transforming growth factor-alpha and epidermal growth factor receptor expression during rat esophageal tumorigenesis.
    Molecular carcinogenesis, 1996, Volume: 15, Issue:2

    Topics: Animals; Base Sequence; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA Primers; ErbB Receptors; Esophageal Neoplasms; Esophagus; Gene Expression; In Situ Hybridization; Male; Molecular Sequence Data; Papilloma; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred F344; RNA, Messenger

1996
A short-term assessment of tumor-promotion activity in the livers of rats treated with two genotoxic methylating agents: dimethylnitrosamine and methylnitrosourea.
    Toxicology letters, 1998, Sep-15, Volume: 98, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Dimethylnitrosamine; DNA Replication; Liver; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Rats; Rats, Inbred F344

1998
Ki-ras and the characteristics of mouse lung tumors.
    Molecular carcinogenesis, 2000, Volume: 28, Issue:3

    Topics: Adenoma; Animals; Apoptosis; Carcinoma; Cell Cycle; Cell Transformation, Neoplastic; Codon; Dimethylnitrosamine; DNA Mutational Analysis; DNA, Neoplasm; Genes, ras; Guanosine Triphosphate; Humans; Lung Neoplasms; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Species Specificity

2000
Cell susceptibility to the cytotoxic effect of the carcinogens dimethylnitrosamine and N-nitrosomethylurea.
    Journal of the National Cancer Institute, 1970, Volume: 44, Issue:2

    Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; Dimethylnitrosamine; Methylnitrosourea

1970
Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc.
    Journal of the National Cancer Institute, 2001, Oct-17, Volume: 93, Issue:20

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carbonates; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelial Cells; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Neoplastic; Hyperplasia; Male; Neoplasm Proteins; Papilloma; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Zinc; Zinc Compounds

2001
Inhibition of the multiplication of herpes simplex virus by aliphatic nitrosamines.
    IARC scientific publications, 1978, Issue:24 Pt 2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Diethylnitrosamine; Dimethylnitrosamine; Humans; Microsomes; Nitrosamines; Rats; Simplexvirus; Virus Replication

1978
Propionibacterium acnes-mediated humoral immune responses to tumor-specific antigens on rat liver cells transformed in vitro by chemical carcinogens.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:6

    Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Liver Neoplasms; Methylnitronitrosoguanidine; Neoplasms, Experimental; Propionibacterium acnes; Rats

1978
Histological conformity of implantation tumors produced by kidney cell lines derived from dimethylnitrosamine-treated rats, with dimethylnitrosamine-induced renal mesenchymal tumors.
    Cancer research, 1978, Volume: 38, Issue:7

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; Kidney; Kidney Neoplasms; Mesenchymoma; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Rats; Transplantation, Homologous

1978
Smooth-muscle-associated contractile protein in renal mesenchymal tumour cells and in transformed cells from DMN-injected rats.
    British journal of cancer, 1976, Volume: 34, Issue:5

    Topics: Actins; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cross Reactions; Cytoskeleton; Dimethylnitrosamine; Fluorescent Antibody Technique; Kidney Neoplasms; Muscle Proteins; Muscle, Smooth; Neoplasms, Experimental; Rats; Rats, Inbred Strains

1976
Morphologic character of transforming renal cell cultures derived from Wistar rats given dimethylnitrosamine.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:5

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Kidney; Nitrosamines; Rats; Time Factors

1977
Distinctive patterns of proliferative activity in kidney cell cultures derived from normal dimethylnitrosamine-treated, and renal tumor-bearing rats.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:6

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Female; Kidney; Kidney Neoplasms; Mesenchymoma; Neoplasms, Experimental; Nitrosamines; Rats; Thymidine

1977
Length of in vivo exposure to a carcinogenic dose of dimethylnitrosamine necessary for subsequent expression of morphological transformation by rat kidney cells in vitro.
    Oncology, 1977, Volume: 34, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; Female; In Vitro Techniques; Kidney; Nitrosamines; Rats; Time Factors

1977
Newer insights into the pathogenesis of liver cancer.
    The American journal of pathology, 1977, Volume: 89, Issue:2

    Topics: Aflatoxins; Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnitrosamine; Hepatectomy; Hydroxyacetylaminofluorene; Liver Neoplasms; Methylazoxymethanol Acetate; Methyldimethylaminoazobenzene; Neoplasms, Experimental; Precancerous Conditions; Skin Neoplasms

1977
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens.
    Cancer research, 1976, Volume: 36, Issue:11 Pt 1

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; Drug Resistance; Ethionine; Hyperplasia; Liver; Liver Neoplasms; Male; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; RNA

1976
Transformed liver cells obtained in culture from hepatectomized rats treated with dimethylnitrosamine (dMN).
    British journal of cancer, 1975, Volume: 31, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Nitrosamines; Rats

1975
Production of epithelial and mesenchymal tumours with rat liver cells transformed in vitro.
    International journal of cancer, 1975, Oct-15, Volume: 16, Issue:4

    Topics: Animals; Carcinosarcoma; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Epithelial Cells; Epithelium; Fibrosarcoma; In Vitro Techniques; Liver; Mesenchymoma; Methylnitronitrosoguanidine; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Nitrosoguanidines; Rats; Rats, Inbred Strains; Sarcoma, Experimental; Transplantation, Isogeneic

1975
The effect produced by some carcinogenic nitrosocompounds on organ cultures from human embryonic lung and kidney tissues.
    International journal of cancer, 1975, Nov-15, Volume: 16, Issue:5

    Topics: Azo Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylnitrosamine; Epithelial Cells; Epithelium; Humans; Hyperplasia; Kidney; Lung; Methylnitrosourea; Necrosis; Nitrosamines; Nitrosourea Compounds; o-Aminoazotoluene; Organ Culture Techniques; Time Factors

1975
Abnormal response of glycolipid synthesis to temperature in transformed BHK cells thermosensitive for growth control.
    Biochemical and biophysical research communications, 1975, Nov-03, Volume: 67, Issue:1

    Topics: Cell Line; Cell Transformation, Neoplastic; Cytosol; Dimethylnitrosamine; Galactosyltransferases; Glycolipids; Mutation; Palmitic Acids; Temperature

1975
Non-histone chromosomal proteins of chemically transformed neoplastic cells in tissue culture.
    Cancer research, 1976, Volume: 36, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Clone Cells; Cricetinae; Dimethylnitrosamine; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Nucleoproteins; Proteins; Ultracentrifugation

1976
Electron microscopic observations on the morphogenesis of renal cell carcinoma induced in rat kidney by dimethylnitrosamine and N-(3,5-dichlorophenyl)succinimide.
    Cancer research, 1976, Volume: 36, Issue:2 Pt 1

    Topics: Adenocarcinoma; Animals; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Chlorobenzenes; Cytoplasm; Dimethylnitrosamine; Kidney; Kidney Neoplasms; Kidney Tubules, Proximal; Male; Neoplasms, Experimental; Nitrosamines; Organoids; Rats; Succinimides

1976
Association between expression of transforming growth factor-alpha and progression of hepatocellular foci to neoplasms.
    Carcinogenesis, 1992, Volume: 13, Issue:8

    Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Chrysenes; Dimethylnitrosamine; Glutathione Transferase; Liver Neoplasms, Experimental; Rats; Transforming Growth Factor alpha

1992
Quantity and saturation degree of dietary fats as modulators of oxidative stress and chemically-induced liver tumours in rats.
    International journal of cancer, 1990, Oct-15, Volume: 46, Issue:4

    Topics: Animals; Biomarkers; Blood Chemical Analysis; Cell Transformation, Neoplastic; Cholesterol; Dietary Fats; Dimethylnitrosamine; Glutathione; Indomethacin; Lipid Peroxidation; Lipids; Liver; Liver Neoplasms; Male; Peptidyl Transferases; Rats; Rats, Inbred Strains; Triglycerides; Weight Gain

1990
Morphological transformation of BALB/3T3 cells by various procarcinogens in the presence of a rat liver S-9 activation system.
    Environmental and molecular mutagenesis, 1990, Volume: 16, Issue:4

    Topics: 2-Naphthylamine; Animals; Biotransformation; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclophosphamide; Dimethylnitrosamine; Dose-Response Relationship, Drug; Fluorenes; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Rats; Rats, Inbred F344

1990
Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine.
    Cancer research, 1990, Mar-01, Volume: 50, Issue:5

    Topics: Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA, Neoplasm; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Transfection

1990
Activation of the c-Ha-ras-1 proto-oncogene by methylation in vitro with alpha-acetoxy-N-nitrosodimethylamine.
    Molecular carcinogenesis, 1989, Volume: 2, Issue:2

    Topics: Animals; Blotting, Southern; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Gene Amplification; Gene Expression Regulation; Genes, ras; Humans; Male; Methylation; Mice; Mice, Inbred CBA; Oligonucleotide Probes; Plasmids; Proto-Oncogene Mas; Taq Polymerase; Transfection

1989
Transforming activity of DNA from rat liver tumors induced by the carcinogen methyl(acetoxymethyl)nitrosamine.
    Molecular carcinogenesis, 1988, Volume: 1, Issue:1

    Topics: Animals; Blotting, Southern; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA Restriction Enzymes; DNA, Neoplasm; Liver Neoplasms; Male; Mice; Mice, Nude; Molecular Weight; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Rats; Transfection

1988
A method for the amplification of chemically induced transformation in C3H/10T1/2 clone 8 cells: its use as a potential screening assay.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:3

    Topics: 2-Naphthylamine; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Diethylnitrosamine; Dimethylnitrosamine; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344

1987
Deregulation and overexpression of c-fos proto-oncogene in rat renal cell-lines and primary tumors induced by dimethylnitrosamine.
    Oncogene, 1988, Volume: 3, Issue:5

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; Gene Expression Regulation; Kidney; Kidney Neoplasms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; RNA, Messenger; Transcription, Genetic

1988