dimethylnitrosamine has been researched along with Body Weight in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (33.73) | 18.7374 |
| 1990's | 20 (24.10) | 18.2507 |
| 2000's | 22 (26.51) | 29.6817 |
| 2010's | 10 (12.05) | 24.3611 |
| 2020's | 3 (3.61) | 2.80 |
| Authors | Studies |
|---|---|
| Rana, SVS; Rani, V; Verma, Y | 1 |
| George, J; Tsuchishima, M; Tsutsumi, M | 1 |
| Choi, BH; Hada, B; Karmacharya, MB; Kim, KH; Park, SR | 1 |
| Chen, CM; Chen, HL; Cheng, WT; Chong, KY; Tang, TY; Tung, YT; Yang, SH | 1 |
| Choi, MH; Hong, ST; Jang, JJ; Jin, Y; Li, S; Uddin, MH | 1 |
| Chen, GF; Cheng, Y; Mai, JY; Ping, J; Wang, MF | 1 |
| Hong, SS; Jung, KH; Kwon, SW; Lee, DH; Lee, HS; Park, IS | 1 |
| Ahmad, R; Ahmed, S; Hasnain, AU; Khan, NU | 1 |
| Ha, JR; Kim, DH; Kim, DY; Oh, SW | 1 |
| Chiu, S; Kinghorn, AD; Rocha, C; Seguin, C; Stoner, GD; Stoner, K; Wang, LS | 1 |
| Kang, JK; Shin, JW; Son, CG; Wang, JH | 1 |
| Hong, SS; Hong, SW; Jung, KH; Lee, DH; Lee, HS; Park, IS; Suh, JK; Zheng, HM | 1 |
| Choi, CY; Choi, JH; Chung, YC; Hwang, YP; Jeong, HG | 1 |
| Liu, C; Liu, P; Lv, J; Wang, L; Yan, X; Zeng, Z | 1 |
| Duan, X; Feng, Q; Fu, Q; Hu, Y; Li, X; Peng, J | 1 |
| Chang, CC; Hsieh, SJ; Hsu, SL; Huang, CY; Lai, JM; Su, LJ; Tseng, TL; Wu, YC; Yang, CH | 1 |
| George, J | 2 |
| George, J; Takase, S; Tsutsumi, M | 1 |
| Lee, MH; Moon, JO; Yoon, S | 1 |
| Chen, T; Kresty, LA; Nines, RG; Peschke, SM; Stoner, GD | 1 |
| George, J; Stern, R | 1 |
| Hsieh, CC; Lin, WC; Shih, CC; Wu, YW | 1 |
| Enjoji, M; Kohjima, M; Kotoh, K; Morizono, S; Nakamuta, M; Tsuruta, S | 1 |
| Hasuike, S; Ido, A; Inui, K; Katsura, T; Kim, I; Kodama, M; Kusumoto, K; Moriuchi, A; Nagata, K; Numata, M; Takahama, Y; Tsubouchi, H; Uto, H | 1 |
| Chen, T; Hwang, H; Nines, RG; Rose, ME; Stoner, GD | 1 |
| Lee, DY; Lee, I; Lee, MG | 1 |
| Cukovic, D; Dombkowski, AA; Kresty, LA; Mele, JM; Nines, R; Reen, RK; Salagrama, S; Stoner, GD | 1 |
| Jung, HS; Kim, EK; Kim, EY; Lee, HS; Soh, Y; Sohn, NW; Sohn, Y | 1 |
| Ohmori, T; Tabei, R | 1 |
| Bompart, G; Bourbon, P; Bouteille, L; Do Phuoc, H | 1 |
| Beppu, T; Hanano, M; Iga, T; Kawasaki, S; Sugiyama, Y; Umekita, N; Wada, T | 1 |
| Ide, G; Ishizeki, S; Iwasaki, I; Murata, N; Ogihara, I; Sakai, K; Takahashi, A; Umeda, T; Yamane, Y | 1 |
| Frenzel, H; Minzlaff, M; Oldiges, H; Teschke, R | 1 |
| Holsapple, MP; McNerney, PJ; Tucker, AN; White, KL | 1 |
| Bassir, O; Maduagwu, EN | 1 |
| Kunke, KS; Strunk, RC | 1 |
| Gabrial, GN; Newberne, PM; Schrager, TF | 1 |
| Quast, JF; Stott, WT; Watanabe, PG | 1 |
| Hayashi, M; Hirose, M; Imaida, K; Ishihara, Y; Ito, H; Ito, N | 1 |
| Mostafa, MH; Ruchirawat, M; Weisburger, EK | 1 |
| Barch, DH; Siglin, JC; Stoner, GD | 1 |
| Khare, L; Siglin, JC; Stoner, GD | 1 |
| Cattley, RC; Conolly, RB; Kato, M; Popp, JA | 1 |
| Ayres, JW; Dunn, SR; Emery, SM; Fitzpatrick, ME; Sandine, WE; Simenhoff, ML; Zollner, GP | 1 |
| Farber, JL; Fong, LY; Li, JX; Magee, PN | 1 |
| Asakura, H; Ichida, T; Komoriya, Y; Matsuda, Y; Matsumoto, K; Nakamura, T; Nishiyama, E; Yamada, A | 1 |
| Atsuchi, N; Ooshima, A; Qi, Z; Takeshita, A; Ueno, H | 1 |
| Fong, LY; Magee, PN | 1 |
| Hagiwara, A; Hasegawa, R; Imaida, K; Ito, N; Sano, M; Shirai, T; Tamano, S | 1 |
| Ikeda, Y; Imaida, K; Kimoto, N; Orita, S; Sakakibara, M; Shirai, T; Suzuki, S; Takahashi, S | 1 |
| Chandrakasan, G; George, J; Rao, KR; Stern, R | 1 |
| Ding, Y; Hong, T; Imamura, M; Kaganoi, J; Kawabe, A; Komoto, I; Li, Z; Maeda, M; Sato, F; Shimada, Y | 1 |
| Enjoji, M; Iwamoto, H; Nakamuta, M; Nakashima, Y; Nawata, H; Sugimoto, R; Tada, S | 1 |
| Enjoji, M; Iwamoto, H; Kato, M; Nakamuta, M; Nakashima, Y; Nawata, H; Sugimoto, R; Tada, S | 1 |
| Enjoji, M; Kato, M; Kotoh, K; Nakamuta, M; Nakashima, Y; Nawata, H; Ohta, S; Sugimoto, R; Tada, S; Tsuruta, S | 1 |
| Eltze, M; Jackisch, R; Jung, A | 1 |
| Grieco, MP; Hendricks, JD; Pierce, DA; Scanlan, RA; Sinnhuber, RO | 1 |
| Aoki, Y; Arai, M; Ito, N; Miyata, Y; Mori, T; Nakanishi, K | 1 |
| Anderson, LM; Ebeling, D; Giner-Sorolla, A | 1 |
| Fong, LY; Newberne, PM | 1 |
| Nafstad, I; Skaare, JU | 1 |
| Evarts, RP; Mostafa, MH | 1 |
| Arai, M; Hirao, K; Nakanishi, K; Shinohara, Y; Sugihara, S | 1 |
| Keyl, AC; Nishie, K; Norred, WP | 1 |
| Ito, N; Moore, MA; Ruchirawat, S; Thamavit, W | 1 |
| Anderson, LM; Carter, JP; Driver, CL; Kovatch, RM; Logsdon, DL | 1 |
| Eskelson, CD; Mufti, SI; Odeleye, OE; Watson, RR | 1 |
| Boothe, DM; Boothe, HW; Corrier, DE; Cullen, JM; Green, RA; Jenkins, WL; Weise, D | 1 |
| Baraona, E; Lasker, JM; Lieber, CS; Ma, XL | 1 |
| Daniel, EM; Stoner, GD | 1 |
| Chi, H; Xu, Y | 1 |
| Hard, GC; Magee, PN; Ogiu, T; Schwartz, AG | 1 |
| Hunt, CM; Stave, GM; Strater, S | 1 |
| Hioki, K; Kise, Y; Komada, H; Nakagawa, M; Yamamoto, M; Yamamura, M | 1 |
| Han, C; Xu, Y | 1 |
| Klaude, M; Persson, G; von der Decken, A | 1 |
| Cater, KC; Gandolfi, AJ; Sipes, IG | 1 |
| Homma, H; Matsui, M; Takanashi, H | 1 |
| Boise, LH; Haggerty, HG; Holsapple, MP; Jordan, SD | 1 |
| Anderson, LM | 1 |
| Bueche, D; Nauss, KM; Newberne, PM | 1 |
| Berger, MR; Bischoff, H; Keppler, BK; Schmähl, D | 1 |
1 trial(s) available for dimethylnitrosamine and Body Weight
| Article | Year |
|---|---|
Biomodulation of the toxic and nutritional effects of small bowel bacterial overgrowth in end-stage kidney disease using freeze-dried Lactobacillus acidophilus.
Topics: Analysis of Variance; Bacterial Infections; Bacterial Toxins; Body Weight; Dimethylamines; Dimethylnitrosamine; Energy Intake; Freeze Drying; Humans; Intestine, Small; Kidney Failure, Chronic; Lactobacillus; Lactobacillus acidophilus; Nutritional Status; Renal Dialysis; Uremia | 1996 |
82 other study(ies) available for dimethylnitrosamine and Body Weight
| Article | Year |
|---|---|
Zinc Oxide Nanoparticles Ameliorate Dimethylnitrosamine-Induced Renal Toxicity in Rat.
Topics: Animals; Antioxidants; Body Weight; Dimethylnitrosamine; Hydrogen Peroxide; Nanoparticles; Oxidative Stress; Rats; Zinc Oxide | 2022 |
Epigallocatechin-3-gallate inhibits osteopontin expression and prevents experimentally induced hepatic fibrosis.
Topics: Animals; Body Weight; Catechin; Collagen Type I; Collagen Type IV; Dimethylnitrosamine; Fibrosis; Hepatic Stellate Cells; Hyaluronic Acid; Liver; Liver Cirrhosis; Malondialdehyde; Osteopontin; Rats | 2022 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) shows therapeutic effect on dimethylnitrosamine (DMN)-induced liver fibrosis in rats.
Topics: Animals; Body Weight; Collagen Type I; Dimethylnitrosamine; Granulocyte-Macrophage Colony-Stimulating Factor; Liver; Liver Cirrhosis; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2022 |
Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation.
Topics: Animals; Body Weight; Dimethylnitrosamine; Disease Models, Animal; Hydroxyproline; Lactoferrin; Liver; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ultrasonography | 2014 |
C3H/He Mice as an Incompatible Cholangiocarcinoma Model by Clonorchis sinensis, Dicyclanil and N-Nitrosodimethylamine.
Topics: Animals; Bile Ducts; Body Weight; Cholangiocarcinoma; Clonorchiasis; Clonorchis sinensis; Dimethylnitrosamine; Disease Models, Animal; Histocytochemistry; Juvenile Hormones; Liver; Male; Mice, Inbred C3H; Spleen | 2016 |
Antifibrotic effect of total flavonoids of Astmgali Radix on dimethylnitrosamine-induced liver cirrhosis in rats.
Topics: Actins; Animals; Blotting, Western; Body Weight; Collagen Type I; Dimethylnitrosamine; Drugs, Chinese Herbal; Flavonoids; Hydroxyproline; Liver; Liver Cirrhosis; Male; Organ Size; Plant Extracts; PPAR gamma; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Uncoupling Protein 2 | 2017 |
Protective effect of morin on dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Actins; Animals; Antioxidants; Body Weight; Collagen Type I; Dimethylnitrosamine; Flavonoids; Liver; Liver Cirrhosis; Liver Function Tests; Male; Organ Size; Phytotherapy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta1 | 2009 |
Operculina turpethum attenuates N-nitrosodimethylamine induced toxic liver injury and clastogenicity in rats.
Topics: Actins; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Convolvulaceae; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver; Male; Muscle, Smooth; Mutagens; Organ Size; Plant Extracts; Rats; Rats, Wistar | 2009 |
Anti-fibrotic effects of a methylenedioxybenzene compound, CW209292 on dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Benzodioxoles; Body Weight; Cell Proliferation; Dimethylnitrosamine; Disease Models, Animal; Female; Hepatic Stellate Cells; Hydroxyproline; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Molecular Structure; Prothrombin Time; Rats; Rats, Sprague-Dawley; Survival Analysis; Thiazoles | 2009 |
Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Chemoprevention; Dimethylnitrosamine; Eating; Esophageal Neoplasms; Fruit; Humans; Interleukin-5; Interleukin-8; Male; Phytotherapy; Rats; Rats, Sprague-Dawley | 2010 |
Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats.
Topics: Animals; Antioxidants; Body Weight; Coffea; Coffee; Cytokines; Dimethylnitrosamine; Disease Models, Animal; Gene Expression; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis; Macrophages; Male; Malondialdehyde; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type II; Organ Size; Phytotherapy; Plant Extracts; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Seeds | 2010 |
The protective effect of resveratrol on dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Antioxidants; Biomarkers; Body Weight; Dimethylnitrosamine; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Anti-fibrotic effects of the anthocyanins isolated from the purple-fleshed sweet potato on hepatic fibrosis induced by dimethylnitrosamine administration in rats.
Topics: Actins; Animals; Anthocyanins; Biomarkers; Body Weight; Chemical Fractionation; Collagen Type I; Collagen Type III; Dimethylnitrosamine; Gene Expression; Ipomoea batatas; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Organ Size; Plant Extracts; Rats; Rats, Sprague-Dawley | 2010 |
[Effect of fuzheng huayu recipe and huangqi tang on DMN-induced experimental liver cirrhosis in rats].
Topics: Animals; Body Weight; Dimethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Liver; Liver Cirrhosis, Experimental; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2010 |
[Effect of gypenosides on DMN-induced liver fibrosis in rats].
Topics: Animals; Body Weight; Dimethylnitrosamine; Glutathione; Glutathione Peroxidase; Gynostemma; Hydroxyproline; Liver; Liver Cirrhosis; Male; Malondialdehyde; Organ Size; Plant Extracts; Rats; Rats, Wistar | 2012 |
Graptopetalum paraguayense ameliorates chemical-induced rat hepatic fibrosis in vivo and inactivates stellate cells and Kupffer cells in vitro.
Topics: Animals; Apoptosis; Body Weight; Cytokines; Dimethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herbal; Ferns; Hepatic Stellate Cells; Inflammation; Kupffer Cells; Liver; Liver Cirrhosis; Male; Organ Size; Plant Extracts; Rats; Spleen | 2013 |
Ascorbic acid concentrations in dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Ascorbic Acid; Body Weight; Collagen; Dimethylnitrosamine; Lipid Peroxides; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar | 2003 |
Expression of hyaluronic acid in N-nitrosodimethylamine induced hepatic fibrosis in rats.
Topics: Actins; Animals; Body Weight; Dimethylnitrosamine; Fibrosis; Hyaluronan Receptors; Hyaluronic Acid; Immunohistochemistry; Liver; Male; Muscle, Smooth; N-Methylaspartate; Necrosis; Nitrosamines; Organ Size; Rats; Time Factors | 2004 |
The flavonoid naringenin inhibits dimethylnitrosamine-induced liver damage in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Body Weight; Dimethylnitrosamine; Flavanones; Flavonoids; Image Processing, Computer-Assisted; Immunohistochemistry; Lipid Peroxidation; Liver Cirrhosis; Liver Function Tests; Male; Malondialdehyde; Organ Size; Rats; Rats, Sprague-Dawley | 2004 |
Chemopreventive effects of a selective nitric oxide synthase inhibitor on carcinogen-induced rat esophageal tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Dimethylnitrosamine; Eating; Enzyme Inhibitors; Esophageal Neoplasms; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Thiourea | 2004 |
Serum hyaluronan and hyaluronidase: very early markers of toxic liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Body Weight; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Hyaluronic Acid; Hyaluronoglucosaminidase; Injections, Intraperitoneal; Liver; Liver Cirrhosis; Liver Function Tests; Male; Organ Size; Rats; Rats, Wistar; Time Factors | 2004 |
Effect of Anoectochilus formosanus on fibrosis and regeneration of the liver in rats.
Topics: Animals; Body Weight; Dimethylnitrosamine; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Orchidaceae; Organ Size; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Water | 2004 |
Remote delivery and expression of soluble type II TGF-beta receptor in muscle prevents hepatic fibrosis in rats.
Topics: Actins; Animals; Body Weight; Collagen Type I; Dimethylnitrosamine; Gene Expression Regulation; Humans; Interleukin-10; Interleukin-12; Liver Cirrhosis; Male; Muscles; Organ Size; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Solubility | 2005 |
Repeated intravenous injection of recombinant human hepatocyte growth factor ameliorates liver cirrhosis but causes albuminuria in rats.
Topics: Alanine Transaminase; Albuminuria; Animals; Body Weight; Dimethylnitrosamine; Hepatectomy; Hepatocyte Growth Factor; Humans; Injections, Intravenous; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Organ Size; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serum Albumin | 2006 |
Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Cyclooxygenase 2; Diet; Dimethylnitrosamine; Dinoprostone; Down-Regulation; Eating; Esophageal Neoplasms; Fruit; JNK Mitogen-Activated Protein Kinases; Male; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Inbred F344; RNA, Messenger | 2006 |
Mineral metabolism in dimethylnitrosamine-induced hepatic fibrosis.
Topics: Animals; Ascites; Body Weight; Calcium; Dimethylnitrosamine; Liver; Liver Cirrhosis; Magnesium; Male; Minerals; Organ Size; Potassium; Rats; Rats, Wistar | 2006 |
Pharmacokinetics of omeprazole after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Body Weight; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Dimethylnitrosamine; Injections, Intravenous; Liver Cirrhosis, Experimental; Male; Omeprazole; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
Effects of phenylethyl isothiocyanate on early molecular events in N-nitrosomethylbenzylamine-induced cytotoxicity in rat esophagus.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome; Isothiocyanates; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Protective effects of Cuscutae semen against dimethylnitrosamine-induced acute liver injury in Sprague-Dawley rats.
Topics: Actins; Alkylating Agents; Animals; Blotting, Western; Body Weight; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Hydroxyproline; Image Processing, Computer-Assisted; Immunohistochemistry; Indicators and Reagents; Liver; Male; Organ Size; Plants, Medicinal; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Reference Standards | 2007 |
Modulation of N-nitrosodimethylamine kidney tumorigenesis by unilateral hydronephrosis and multiple putrescine administrations.
Topics: Animals; Body Weight; Dimethylnitrosamine; Female; gamma-Glutamyltransferase; Hydronephrosis; Kidney; Kidney Neoplasms; Liver Neoplasms; Nephrectomy; Organ Size; Putrescine; Rats; Rats, Inbred Strains; Trypan Blue | 1983 |
[Action of F- on liver metabolism of dimethylnitrosamine and benzo(a)pyrene in the rat].
Topics: Animals; Benzo(a)pyrene; Benzopyrene Hydroxylase; Benzopyrenes; Body Weight; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Fluorides; Liver; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats | 1983 |
Hepatic transport of indocyanine green in dogs chronically intoxicated with dimethylnitrosamine.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Body Weight; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Dogs; Drug Interactions; Indocyanine Green; Injections, Intravenous; Kinetics; Liver; Liver Diseases | 1984 |
Suppressive effect of cupric acetate on DNA alkylation, DNA synthesis and tumorigenesis in the liver of dimethylnitrosamine-treated rats.
Topics: Alkylation; Animals; Body Weight; Copper; Depression, Chemical; Dimethylnitrosamine; DNA; Liver; Liver Neoplasms, Experimental; Male; Organometallic Compounds; Rats; Rats, Inbred Strains | 1984 |
Effect of chronic alcohol consumption on tumor incidence due to dimethylnitrosamine administration.
Topics: Alcoholism; Animals; Body Weight; Dimethylnitrosamine; Ethanol; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Effects of N-nitrosodimethylamine on humoral immunity.
Topics: Animals; Antibody Formation; Biotransformation; Body Weight; Dimethylnitrosamine; Erythrocytes; Female; Lipopolysaccharides; Liver; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mononuclear Phagocyte System; Organ Size | 1984 |
A comparative assessment of toxic effects of dimethylnitrosamine in six different species.
Topics: Animals; Body Weight; Cats; Cercopithecus; Chemical and Drug Induced Liver Injury; Diet; Dimethylnitrosamine; Ducks; Guinea Pigs; Haplorhini; Liver Function Tests; Lizards; Male; Organ Size; Rats; Species Specificity | 1980 |
Complement synthesis by guinea pig peritoneal macrophages: failure to detect chemical carcinogens.
Topics: Animals; Body Weight; Carcinogens; Complement C2; Complement C4; Complement System Proteins; Dimethylnitrosamine; Drug Evaluation, Preclinical; Female; Guinea Pigs; Immune Adherence Reaction; Lethal Dose 50; Macrophages; Male; Peritoneum | 1981 |
Zinc deficiency, alcohol, and retinoid: association with esophageal cancer in rats.
Topics: Animals; Body Weight; Cocarcinogenesis; Copper; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Ethanol; Isotretinoin; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tretinoin; Zinc | 1982 |
Differentiation of the mechanisms of oncogenicity of 1,4-dioxane and 1,3-hexachlorobutadiene in the rat.
Topics: Alkylation; Animals; Body Weight; Butadienes; Carcinogens; Dimethylnitrosamine; Dioxanes; Dioxins; DNA; DNA Repair; Male; Organ Size; Rats; Rats, Inbred Strains | 1981 |
Effects of chloroform and dimethylnitrosamine on renal carcinogenesis in unilaterally nephrectomized rats fed formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide.
Topics: Animals; Body Weight; Carcinogens; Chloroform; Dimethylnitrosamine; Kidney Neoplasms; Male; Neoplasms, Experimental; Nephrectomy; Nitrofurans; Organ Size; Rats; Rats, Inbred F344; Thiazoles | 1981 |
Effect of indole on N-nitrosodimethylamine demethylase in rats treated with carbon tetrachloride.
Topics: Animals; Body Weight; Carbon Tetrachloride; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Indoles; Liver; Male; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Rats; Time Factors | 1981 |
Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Calcium; Carcinogens; Diet; Dimethylnitrosamine; Ellagic Acid; Esophageal Neoplasms; Isothiocyanates; Male; Rats; Rats, Inbred F344; Sulindac; Time Factors | 1995 |
Evaluation of dose and treatment duration on the esophageal tumorigenicity of N-nitrosomethylbenzylamine in rats.
Topics: Animals; Body Weight; Carcinogens; Cell Division; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Esophageal Neoplasms; Esophagus; Evaluation Studies as Topic; Injections, Subcutaneous; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 1995 |
Relationship between hepatocyte necrosis, proliferation, and initiation induced by diethylnitrosamine in the male F344 rat.
Topics: Animals; Body Weight; Bromodeoxyuridine; Cell Division; Dimethylnitrosamine; Glutathione Transferase; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Necrosis; Organ Size; Placenta; Rats; Rats, Inbred F344 | 1993 |
Cell proliferation and esophageal carcinogenesis in the zinc-deficient rat.
Topics: Aging; Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Dimethylnitrosamine; Esophageal Neoplasms; Esophagus; Male; Mitotic Index; Papilloma; Rats; Rats, Sprague-Dawley; Reference Values; S Phase; Time Factors; Weaning; Zinc | 1996 |
Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Dimethylnitrosamine; Fibrinogen; Hepatocyte Growth Factor; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serum Albumin; Survival Rate | 1997 |
Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.
Topics: Adenoviridae; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Dimethylnitrosamine; Genetic Therapy; Genetic Vectors; Hyaluronic Acid; Liver; Liver Cirrhosis, Experimental; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Signal Transduction; Survival Rate; Transforming Growth Factor beta | 1999 |
Dietary zinc deficiency enhances esophageal cell proliferation and N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumor incidence in C57BL/6 mouse.
Topics: Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Dimethylnitrosamine; Eating; Epithelial Cells; Esophageal Neoplasms; Esophagus; Male; Mice; Mice, Inbred C57BL; Zinc | 1999 |
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation.
Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinoma, Hepatocellular; Clofibrate; Cocarcinogenesis; Diethylhexyl Phthalate; Dimethylnitrosamine; Dose-Response Relationship, Drug; Glutathione S-Transferase pi; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; No-Observed-Adverse-Effect Level; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344 | 1999 |
Enhancing effects of 2-amino-4,5-diphenylthiazole-induced polycystic kidneys on renal carcinogenesis in rats treated with dimethylnitrosamine.
Topics: Animals; Body Weight; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Immunohistochemistry; Kidney Neoplasms; Male; Organ Size; Polycystic Kidney Diseases; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Thiazoles | 2000 |
Dimethylnitrosamine-induced liver injury in rats: the early deposition of collagen.
Topics: Animals; Apoptosis; Behavior, Animal; Body Weight; Collagen; Dimethylnitrosamine; DNA; Eating; Hemorrhage; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Organ Size; Proteins; Rats; Rats, Wistar; Survival Rate | 2001 |
Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by JTE-522, a selective COX-2 inhibitor.
Topics: Animals; Benzenesulfonates; Body Weight; Carcinogens; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dimethylnitrosamine; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Esophagus; Isoenzymes; Male; Oxazoles; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Actins; Amides; Animals; Body Weight; Collagen; Dimethylnitrosamine; Enzyme Inhibitors; Hydroxyproline; Intracellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis; Male; Muscle, Smooth; Organ Size; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; RNA, Messenger | 2001 |
Pirfenidone inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Blotting, Northern; Body Weight; Collagen; Dimethylnitrosamine; Hydroxyproline; Liver Cirrhosis; Male; Pyridones; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 2001 |
Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Body Weight; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen Type I; Dimethyl Sulfoxide; Dimethylnitrosamine; Fibrosis; Free Radical Scavengers; Gene Expression Regulation; Hydroxyproline; Kupffer Cells; Lipopolysaccharides; Liver; Liver Diseases; Luciferases; Male; NF-kappa B; Nitric Oxide; Organ Size; Promoter Regions, Genetic; Rats; Rats, Wistar; Recombinant Fusion Proteins; RNA, Messenger; Severity of Illness Index; Tumor Necrosis Factor-alpha; Weight Loss | 2001 |
Cytoplasmic changes in level and distribution of glucose-6-phosphatase activities from rat liver during diethylnitrosamine-induced carcinogenesis.
Topics: Animals; Body Weight; Cytoplasm; Dimethylnitrosamine; Female; Glucose-6-Phosphatase; In Vitro Techniques; Liver; Liver Neoplasms; Microsomes, Liver; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Time Factors | 1977 |
Carcinogenicity and acute toxicity of dimethylnitrosamine in rainbow trout (Salmo gairdneri).
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Species Specificity; Trout | 1978 |
Long-term experiment of maximal non-carcinogenic dose of dimethylnitrosamine for carcinogenesis in rats.
Topics: Animals; Body Weight; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Liver Neoplasms, Experimental; Male; Maximum Allowable Concentration; Rats | 1979 |
Effects of imipramine, nitrite, and dimethylnitrosamine on reproduction in mice.
Topics: Animals; Birth Weight; Body Weight; Dimethylnitrosamine; Drug Interactions; Female; Fertility; Imipramine; Mice; Nitrites; Nitrosamines; Reproduction | 1978 |
Nitrosobenzylmethylamine, zinc deficiency and oesophageal cancer.
Topics: Animals; Benzyl Compounds; Body Weight; Carcinogens; Copper; Dimethylnitrosamine; Esophageal Neoplasms; Growth; Hair; Male; Nitrosamines; Rats; Time Factors; Tissue Distribution; Zinc | 1978 |
Interaction of vitamin E and selenium with the hepatotoxic agent dimethylnitrosamine.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Liver; Male; Nitrosamines; Organ Size; Rats; Selenium; Vitamin E | 1978 |
The effect of L-tryptophan and certain other amino acids on liver nitrosodimethylamine demethylase activity.
Topics: Age Factors; Animals; Body Weight; Cysteine; Dimethylnitrosamine; Liver; Male; Organ Size; Oxidoreductases, N-Demethylating; Rats; Tryptophan | 1978 |
Combination effect of citrinin and other chemicals on rat kidney tumorigenesis.
Topics: Animals; Benzopyrans; Body Weight; Chlorobenzenes; Citrinin; Dimethylnitrosamine; Kidney; Kidney Neoplasms; Male; Mycotoxins; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Succinimides | 1976 |
Effects of short-term administration of nitrosamines on rat hepatic microsomal enzymes.
Topics: Aniline Hydroxylase; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; In Vitro Techniques; Liver; Male; Microsomes, Liver; Nitrobenzoates; Nitrosamines; Organ Size; Pentobarbital; Rats; Ribosomal Proteins | 1975 |
Lack of modulation effects of praziquantel on DMN-induced lesion development in the Syrian hamster liver.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Cricetinae; Dimethylnitrosamine; Drug Interactions; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Organ Size; Praziquantel | 1992 |
Characterization of ethanol's enhancement of tumorigenesis by N-nitrosodimethylamine in mice.
Topics: Adenoma; Animals; Body Weight; Dimethylnitrosamine; Drug Synergism; Ethanol; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mice | 1992 |
Vitamin E inhibition of lipid peroxidation and ethanol-mediated promotion of esophageal tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Dimethylnitrosamine; Eating; Esophageal Neoplasms; Ethane; Ethanol; Female; Free Radicals; Lipid Peroxidation; Liver; Malondialdehyde; Mice; Mice, Inbred C57BL; Organ Size; Vitamin A; Vitamin E | 1992 |
Dimethylnitrosamine-induced hepatotoxicosis in dogs as a model of progressive canine hepatic disease.
Topics: Animals; Body Weight; Dimethylnitrosamine; Disease Models, Animal; Dog Diseases; Dogs; Female; Liver; Liver Diseases; Male; Microscopy, Electron; Random Allocation | 1992 |
Effects of ethanol consumption on bioactivation and hepatotoxicity of N-nitrosodimethylamine in rats.
Topics: Alanine Transaminase; Alcohol Drinking; Animals; Aspartate Aminotransferases; Biotransformation; Body Weight; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ethanol; Liver; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Oxygen Consumption; Rats; Rats, Inbred Strains | 1991 |
The effects of ellagic acid and 13-cis-retinoic acid on N-nitrosobenzylmethylamine-induced esophageal tumorigenesis in rats.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinogens; Diet; Dimethylnitrosamine; Drug Synergism; Ellagic Acid; Esophageal Neoplasms; Male; Rats; Rats, Inbred F344; Tretinoin | 1991 |
The effect of Chinese tea on the occurrence of esophageal tumors induced by N-nitrosomethylbenzylamine formed in vivo.
Topics: Animals; Body Weight; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Humans; Male; Papilloma; Rats; Rats, Inbred Strains; Tea | 1990 |
Investigation into the effect of DHEA on renal carcinogenesis induced in the rat by a single dose of DMN.
Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Cocarcinogenesis; Dehydroepiandrosterone; Diet; Dimethylnitrosamine; Dose-Response Relationship, Drug; Kidney Neoplasms; Male; Organ Size; Rats; Rats, Inbred Strains | 1990 |
Effect of normal aging on the activity of human hepatic cytochrome P450IIE1.
Topics: Adult; Aged; Aging; Alcohol Drinking; Body Weight; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Female; Humans; Liver; Male; Middle Aged; Oxidoreductases, N-Demethylating; Regression Analysis; Smoking | 1990 |
Effect of dietary molybdenum on esophageal carcinogenesis in rats induced by N-methyl-N-benzylnitrosamine.
Topics: Animals; Body Weight; Carcinogens; Diet; Dimethylnitrosamine; Dose-Response Relationship, Drug; Esophageal Neoplasms; Esophagus; Male; Molybdenum; Rats; Rats, Inbred F344 | 1990 |
The effect of Chinese tea on occurrence of esophageal tumor induced by N-nitrosomethylbenzylamine in rats.
Topics: Animals; Body Weight; Carcinogens; Dimethylnitrosamine; Esophageal Neoplasms; Female; Male; Rats; Rats, Inbred Strains; Tea | 1990 |
Combined effect of dimethylnitrosamine and a lysine-restricted diet on O6-methylguanine-DNA methyltransferase levels in mouse tissues.
Topics: Animals; Body Weight; Dimethylnitrosamine; DNA; Kidney; Liver; Lung; Lysine; Male; Methyltransferases; Mice; Mice, Inbred Strains; O(6)-Methylguanine-DNA Methyltransferase; Reference Values | 1989 |
Characterization of dimethylnitrosamine-induced focal and nodular lesions in the livers of newborn mice.
Topics: Animals; Animals, Newborn; Body Weight; Dimethylnitrosamine; Female; gamma-Glutamyltransferase; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Mice; Phenobarbital; Sex Factors | 1985 |
Effects of administration of N-nitrosodialkylamines and N-nitrodiethylamine on hepatic UDP-glucuronosyltransferase activity in Wistar rats.
Topics: Aminophenols; Animals; Body Weight; Diethylamines; Diethylnitrosamine; Dimethylnitrosamine; Glucuronosyltransferase; Injections, Intraperitoneal; Male; Microsomes, Liver; Nitrophenols; Nitrosamines; Organ Size; Rats; Rats, Inbred Strains | 1988 |
Differential effects of coadministration of aminoacetonitrile on immunosuppression and hepatotoxicity produced by dimethylnitrosamine.
Topics: Acetonitriles; Aminoacetonitrile; Animals; Body Weight; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Drug Interactions; Female; Immunosuppression Therapy; Liver; Mice; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Time Factors | 1988 |
Increased numbers of N-nitrosodimethylamine-initiated lung tumors in mice by chronic co-administration of ethanol.
Topics: Animals; Body Weight; Dimethylnitrosamine; Drug Synergism; Ethanol; Lung Neoplasms; Mice | 1988 |
Effect of vitamin A nutriture on experimental esophageal carcinogenesis.
Topics: Animals; Body Weight; Diet; Dimethylnitrosamine; Esophageal Neoplasms; Liver; Male; Nutritional Status; Rats; Rats, Inbred Strains; Vitamin A; Vitamin A Deficiency | 1987 |
Efficacy of beta-diketonato complexes of titanium, zirconium, and hafnium against chemically induced autochthonous colonic tumors in rats.
Topics: Animals; Body Weight; Carcinogens; Colonic Neoplasms; Dimethylnitrosamine; Hafnium; Male; Metals; Organometallic Compounds; Rats; Rats, Inbred Strains; Titanium; Zirconium | 1987 |