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dimethylnitrosamine and Abnormalities, Autosome

dimethylnitrosamine has been researched along with Abnormalities, Autosome in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199015 (53.57)18.7374
1990's10 (35.71)18.2507
2000's1 (3.57)29.6817
2010's1 (3.57)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Arimoto-Kobayashi, S; Fujii, A; Goto, Y; Miyamoto, K; Mori, E; Negishi, T; Okamoto, K; Taira, K; Yamada, K1
Fujiishi, Y; Hamada, S; Hattori, A; Kawabata, M; Kawasako, K; Nakadate, K; Nakagawa, M; Narumi, K; Ohyama, W; Okada, E; Takasawa, H; Takashima, R; Wako, Y; Yasunaga, K1
Zimmering, S1
de Brij, RJ; den Engelse, L; Floot, BG; Tates, AD1
Ockey, CH; Swindell, JA1
Thust, R1
Ikeuchi, T; Sasaki, M1
Krishna, G; Theiss, JC1
Dianovský, J; Siviková, K1
Bean, CL; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB1
Siviková, K1
Bauchinger, M; Doehmer, J; Glatt, HR; Kulka, U1
Monteith, DK; Vanstone, J1
Callander, RD; Clay, P; Elcombe, CR; Elliott, BM; Mackay, JM1
Morales-Ramírez, P; Vallarino-Kelly, T1
Asakura, S; Daimon, H; Sagami, F; Sawada, S1
Kamiguchi, Y; Watanabe, S1
Bauknecht, T; Bayer, U; Vogel, W; Wild, D1
Becker, FF1
Grund, E; Mendel, J; Thust, R; Warzok, R1
Lo, LW; Stich, HF1
Jenssen, D; Ramel, C1
Matter, BE1
De Vogel, N; Meijers, M; Natarajan, AT; Tates, AD; Van Buul, PP1
Bahner, B; Lilly, LJ; Mages, PN1
Fukuda, I; Morita, T; Nagaki, T; Okumura, K1
Eckl, PM; Jirtle, RL; Michalopoulos, G; Strom, SC1
Archer, MC; Heddle, JA; Mehta, R; Ronen, A; Silinskas, KC; Zucker, PF1

Other Studies

28 other study(ies) available for dimethylnitrosamine and Abnormalities, Autosome

ArticleYear
Mismatch repair systems might facilitate the chromosomal recombination induced by N-nitrosodimethylamine, but not by N-nitrosodiethylamine, in Drosophila.
    Mutagenesis, 2020, 03-27, Volume: 35, Issue:2

    Topics: Animals; Chromosome Aberrations; Chromosomes; Diethylnitrosamine; Dimethylnitrosamine; DNA Breaks, Double-Stranded; DNA Mismatch Repair; DNA Repair; Drosophila melanogaster; Mutagenesis; Recombination, Genetic

2020
Evaluation of a repeated dose liver micronucleus assay in rats treated with two genotoxic hepatocarcinogens, dimethylnitrosamine and 2-acetylaminofluorene: the possibility of integrating micronucleus tests with multiple tissues into a repeated dose genera
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Volume: 780-781

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Bone Marrow; Carcinogens; Chromosome Aberrations; Cooperative Behavior; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Gastrointestinal Tract; Hepatocytes; Humans; Japan; Liver; Male; Micronucleus Tests; Organ Specificity; Rats; Rats, Sprague-Dawley; Societies, Pharmaceutical

2015
Review of the current status of the mei-9a test for chromosome loss in Drosophila melanogaster: an assay with radically improved detection capacity for chromosome lesions induced by methyl methanesulfonate (MMS), dimethylnitrosamine (DMN), and especially
    Mutation research, 1981, Volume: 83, Issue:1

    Topics: Animals; Chromosome Aberrations; Chromosome Deletion; Diethylnitrosamine; Dimethylnitrosamine; Drosophila melanogaster; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Procarbazine

1981
The induction of chromosomal damage in rat hepatocytes and lymphocytes. II. Alkylation damage and repair of rat-liver DNA after diethylnitrosamine, dimethylnitrosamine and ethyl methanesulphonate in relation to clastogenic effects.
    Mutation research, 1983, Volume: 107, Issue:1

    Topics: Alkylation; Animals; Carcinogens; Chromosome Aberrations; Diethylnitrosamine; Dimethylnitrosamine; DNA; Ethyl Methanesulfonate; Liver; Lymphocytes; Male; Nitrosamines; Rats; Rats, Inbred Strains

1983
Cytogenetic changes during the early stages of liver carcinogenesis in Chinese hamster: an in vivo--in vitro comparison.
    Cancer genetics and cytogenetics, 1983, Volume: 10, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Cricetinae; Cricetulus; Dimethylnitrosamine; Karyotyping; Liver; Liver Neoplasms; Male; Metaphase; Neoplasms, Experimental

1983
Interindividual variation of carcinogen activation by human liver homogenates. A study using dimethylnitrosamine (DMN) and cyclophosphamide (CP) as precursor genotoxic agents and clastogenicity and induction of sister chromatid exchanges in Chinese hamste
    Archiv fur Geschwulstforschung, 1982, Volume: 52, Issue:2

    Topics: Animals; Chromosome Aberrations; Cricetinae; Crossing Over, Genetic; Culture Techniques; Cyclophosphamide; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Liver; Mitosis; Muridae; Mutation; Neoplasms, Experimental; Sister Chromatid Exchange; Tissue Extracts

1982
Differential inducibility of chromosome aberrations and sister-chromatid exchanges by indirect mutagens in various mammalian cell lines.
    Mutation research, 1981, Volume: 90, Issue:2

    Topics: Animals; Benzopyrenes; Cell Line; Chromosome Aberrations; Chromosomes; Cricetinae; Crossing Over, Genetic; Cyclophosphamide; Dimethylnitrosamine; Humans; Mutagens; Phenotype; Rats; Sister Chromatid Exchange

1981
Concurrent analysis of cytogenetic damage in vivo: a multiple endpoint-multiple tissue approach.
    Environmental and molecular mutagenesis, 1995, Volume: 25, Issue:4

    Topics: Acrylamide; Acrylamides; Animal Testing Alternatives; Animals; Bone Marrow; Bone Marrow Cells; Carcinogens; Cellulose; Chlorambucil; Chromosome Aberrations; Cyclophosphamide; Dimethylnitrosamine; Mice; Micronucleus Tests; Mutagens; Rats; Spleen; Vincristine; X-Rays

1995
Induction of chromosomal aberrations, sister-chromatid exchanges and cell-cycle delay in cow peripheral blood lymphocytes treatment with two N-nitroso compounds in vitro.
    Mutation research, 1993, Volume: 290, Issue:2

    Topics: Analysis of Variance; Animals; Cattle; Cell Cycle; Chromosome Aberrations; Dimethylnitrosamine; Female; Kinetics; Lymphocytes; Metaphase; Mutagens; Nitrosourea Compounds; Sister Chromatid Exchange

1993
A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells.
    Mutation research, 1995, Volume: 346, Issue:4

    Topics: Alkylating Agents; B-Lymphocytes; Cell Line; Chromosome Aberrations; Dimethylnitrosamine; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Erythroid Precursor Cells; Guanine; Humans; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea

1995
Clastogenic effects of N-nitrosodimethylamine and dinitrosoglycolurile in murine bone marrow cells and cow lymphocytes.
    Neoplasma, 1994, Volume: 41, Issue:1

    Topics: Animals; Bone Marrow Cells; Cattle; Chromosome Aberrations; Dimethylnitrosamine; Imidazoles; Lymphocytes; Male; Mice; Mice, Inbred ICR; Mutagens; Nitroso Compounds

1994
Cytogenetic effects of promutagens in genetically engineered V79 Chinese hamster cells expressing cytochromes P450.
    European journal of pharmacology, 1993, Apr-01, Volume: 228, Issue:5-6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Genetic Engineering; Mutagens; Rats; Sister Chromatid Exchange

1993
Comparison of the microgel electrophoresis assay and other assays for genotoxicity in the detection of DNA damage.
    Mutation research, 1995, Volume: 345, Issue:3-4

    Topics: Analysis of Variance; Animals; Benzo(a)pyrene; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Cyclophosphamide; Dimethylnitrosamine; DNA; DNA Damage; DNA Repair; Electrophoresis, Agar Gel; Erythrocytes; Fibroblasts; Liver; Lung; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mutagenicity Tests; Mutagens; Rats; Rats, Wistar; Reproducibility of Results

1995
Evaluation of phenobarbital/beta-naphthoflavone as an alternative S9-induction regime to Aroclor 1254 in the rat for use in in vitro genotoxicity assays.
    Mutagenesis, 1995, Volume: 10, Issue:6

    Topics: Administration, Oral; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Chlorodiphenyl (54% Chlorine); Chromosome Aberrations; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Female; Humans; Liver Extracts; Lymphocytes; Male; Mutagenicity Tests; Phenobarbital; Rats; Salmonella typhimurium

1995
Pharmacokinetic parameters determined from the clastogenic activity of ethylnitrosourea and dimethylnitrosamine in mice in vivo.
    Mutation research, 1998, Feb-13, Volume: 412, Issue:3

    Topics: Animals; Chromosome Aberrations; Dimethylnitrosamine; Erythrocytes; Ethylnitrosourea; Gamma Rays; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Mutagens

1998
A short-term assessment of tumor-promotion activity in the livers of rats treated with two genotoxic methylating agents: dimethylnitrosamine and methylnitrosourea.
    Toxicology letters, 1998, Sep-15, Volume: 98, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Dimethylnitrosamine; DNA Replication; Liver; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Rats; Rats, Inbred F344

1998
Chromosome analysis of human spermatozoa following in vitro exposure to cyclophosphamide, benzo(a)pyrene and N-nitrosodimethylamine in the presence of rat liver S9.
    Mutation research, 2001, Apr-05, Volume: 491, Issue:1-2

    Topics: Animals; Benzo(a)pyrene; Biotransformation; Chromosome Aberrations; Cricetinae; Cyclophosphamide; Dimethylnitrosamine; Female; Humans; In Vitro Techniques; Liver; Male; Mutagens; Rats; Spermatozoa

2001
Comparative in vivo mutagenicity testing by SCE and micronucleus induction in mouse bone marrow.
    Human genetics, 1977, Mar-14, Volume: 35, Issue:3

    Topics: Animals; Bromodeoxyuridine; Chromatids; Chromosome Aberrations; Crossing Over, Genetic; Cyclophosphamide; Diethylnitrosamine; Dimethylnitrosamine; Drug Evaluation, Preclinical; Floxuridine; Methylnitronitrosoguanidine; Mice; Mutagens; Triazenes; Triaziquone

1977
Alteration of hepatocytes by subcarcinogenic exposure to n-2-fluorenylacetamide.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Chick Embryo; Chromosome Aberrations; Diet; Dimethylnitrosamine; Fluorenes; Hydroxyacetylaminofluorene; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred ACI

1975
Use of human-liver microsomes from kidney-transplant donors for the induction of chromatid aberrations and sister-chromatid exchanges by means of pre-carcinogens in Chinese hamster cells in vitro.
    Mutation research, 1978, Volume: 51, Issue:3

    Topics: Biotransformation; Cell Line; Chromosome Aberrations; Crossing Over, Genetic; Cyclophosphamide; Dimethylnitrosamine; Drug Evaluation, Preclinical; Genetic Techniques; Humans; Kidney Transplantation; Microsomes, Liver; Mutagens; Nitrosamines

1978
The use of short-term tests to measure the preventive action of reducing agents on formation and activation of carcinogenic nitroso compounds.
    Mutation research, 1978, Volume: 57, Issue:1

    Topics: Adolescent; Adult; Animals; Ascorbic Acid; Cells, Cultured; Chromosome Aberrations; Cysteamine; Cysteine; Dimethylnitrosamine; DNA Repair; Drug Interactions; Gallic Acid; Humans; In Vitro Techniques; Mice; Nitroso Compounds; Propyl Gallate

1978
Factors affecting the induction of micronuclei at low doses of X-rays, MMS and dimethylnitrosamine in mouse erythroblasts.
    Mutation research, 1978, Volume: 58, Issue:1

    Topics: Animals; Caffeine; Cell Cycle; Cell Nucleus; Chromosome Aberrations; Dimethylnitrosamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Erythroblasts; Erythrocytes; Male; Methyl Methanesulfonate; Mice; Mice, Inbred CBA; Mutagens; Phenobarbital; X-Rays

1978
Problems of testing drugs for potential mutagenicity.
    Mutation research, 1976, Volume: 38, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Biotransformation; Carcinogens; Chromosome Aberrations; Dimethylnitrosamine; Drug Evaluation, Preclinical; Methylnitronitrosoguanidine; Mutagens

1976
Cytogenetic effects of mutagens/carcinogens after activation in a microsomal system in vitro I. Induction of chromosome aberrations and sister chromatid exchanges by diethylnitrosamine (DEN) and dimethylnitrosamine (DMN) in CHO cells in the presence of ra
    Mutation research, 1976, Volume: 37, Issue:1

    Topics: Carcinogens; Cell Line; Chromatids; Chromosome Aberrations; Diethylnitrosamine; Dimethylnitrosamine; Microsomes, Liver; Mutagens; Nitrosamines

1976
Chromosomes aberrations induced in rat lymphocytes by N-nitroso compounds as a possible basis for carcinogen screening.
    Nature, 1975, Dec-18, Volume: 258, Issue:5536

    Topics: Animals; Cell Division; Chromosome Aberrations; Chromosomes; Dimethylnitrosamine; Liver; Lymphocytes; Nitrosamines; Rats

1975
Effect of pH on the activity and stability of clastogens in the in vitro chromosomal aberration test with Chinese hamster ovary K1 cells.
    Mutation research, 1991, Volume: 262, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cells, Cultured; Chromatography, High Pressure Liquid; Chromosome Aberrations; Cricetinae; Culture Media; Dimethylnitrosamine; Female; Half-Life; Hydrogen-Ion Concentration; In Vitro Techniques; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens

1991
Induction of sister chromatid exchanges in cultured adult rat hepatocytes by directly and indirectly acting mutagens/carcinogens.
    Carcinogenesis, 1987, Volume: 8, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cells, Cultured; Chromosome Aberrations; Cyclophosphamide; Dimethylnitrosamine; Female; Liver; Mutagens; Rats; Rats, Inbred F344; Sister Chromatid Exchange

1987
Micronucleus formation induced in rat liver and esophagus by nitrosamines.
    Cancer letters, 1987, Volume: 35, Issue:3

    Topics: Animals; Cell Nucleus; Chromosome Aberrations; Diethylnitrosamine; Dimethylnitrosamine; Esophagus; Liver; Male; Mutagenicity Tests; Mutagens; Nitrosamines; Rats; Rats, Inbred Strains

1987