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dimethylhydrazines and Cell Transformation, Neoplastic

dimethylhydrazines has been researched along with Cell Transformation, Neoplastic in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199027 (64.29)18.7374
1990's8 (19.05)18.2507
2000's4 (9.52)29.6817
2010's3 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuznietsova, HM; Ogloblya, OV; Rybalchenko, VK1
Du, J; Levi, E; Majumdar, AP; Misra, S; Patel, BB1
Fan, D; Jin, H; Mei, Q; Wang, Z; Xu, R1
Aggarwal, R; Agnihotri, N; Kansal, S; Negi, AK; Sandhir, R; Sarotra, P; Sharma, G1
Saini, MK; Sanyal, SN1
Mełeń-Mucha, G; Niewiadomska, H1
Fukura, M; Hayashi, N; Takase, S; Tsuchishima, M; Tsutsumi, M; Yano, H1
Columbano, A; Rajalakshmi, S; Sarma, DS1
Fisher, ER; McCoy, MM; Paulson, JD1
Jacobs, LR1
Matveev, VV; Melikiants, AG; Melikiants, LM1
Bruce, WR; Medline, A; Wargovich, MJ1
Sunter, JP1
Costa, NL; Traynor, OJ; Wood, CB1
Augenlicht, LH; Kobrin, D1
Chang, WW2
Chaves, P; Cravo, M; Ferra, MA; Fidalgo, P; Gouveia-Oliveira, A; Mira, FC; Nobre-Leitão, C1
Altmann, GG; Lala, PK1
Lipkin, M1
Deschner, EE; Long, FC; Maskens, AP1
Delapierre, F; Laumonier, R; Tayot, J1
Elkort, RJ; Handler, AH; Mozden, PJ1
Allfrey, VG; Boffa, LC; Vidali, G2
Pozharisskiĭ, KM1
Balis, ME; Ball, WJ; Salser, JS1
Beck, N; Buhr, H; Hupp, T; Ivancovic, S1
Hoshino, H; Nagamachi, Y; Nakano, G; Resau, JH; Sakamoto, K; Shamsuddin, AM; Yuasa, Y1
Castonguay, A; Goldblatt, PJ; Gunning, WT; Stoner, GD1
Donchev, N; Savov, G1
Brasitus, TA; Davidson, NO; Jacoby, RF; Llor, X; Teng, BB1
Baum, CL; Bolt, MJ; Brasitus, TA; Dudeja, PK; Sitrin, MD; Wali, RK1
Calderó, J; Campo, E; Cardesa, A; Viñas, J1
Deschner, EE1
Cheng, HF; Cole, DA; Lindholm, PA; Stevens, RH1
Andrianopoulos, GD; Bombeck, CT; Misumi, A; Nelson, RL; Nyhus, LM1
Suzuki, H; Umehara, N1
Iriyama, K; Iwata, Y; Matsumoto, K; Suzuki, H; Yamamoto, J1
Davey, PG; McGuinness, EE; Nicol, S; Wormsley, KG1
Barkla, DH; Kennedy, MF; Tutton, PJ1
D'Ambrosio, SM; Kamat, PL; Kumari, HL; Milo, GE; Witiak, DT1

Reviews

2 review(s) available for dimethylhydrazines and Cell Transformation, Neoplastic

ArticleYear
Biology of large bowel cancer. Present status and research frontiers.
    Cancer, 1975, Volume: 36, Issue:6 Suppl

    Topics: Adenoma; Adult; Animals; Cell Division; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; DNA, Neoplasm; Epithelial Cells; Epithelium; Female; Humans; Male; Multiple Endocrine Neoplasia; Neoplasms, Experimental; Rectal Neoplasms

1975
Animal models of carcinogenesis.
    Progress in clinical and biological research, 1988, Volume: 279

    Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal

1988

Other Studies

40 other study(ies) available for dimethylhydrazines and Cell Transformation, Neoplastic

ArticleYear
Impact of dihydropyrrol derivative on the normal colonic mucosa of DMH-induced colon cancer rats compared with 5-fluorouracil.
    Experimental oncology, 2013, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Fluorouracil; Intestinal Mucosa; Male; Pyrroles; Pyrrolidinones; Rats; Rats, Wistar

2013
Combination of aging and dimethylhydrazine treatment causes an increase in cancer-stem cell population of rat colonic crypts.
    Biochemical and biophysical research communications, 2009, Jul-31, Volume: 385, Issue:3

    Topics: Aging; Animals; Carcinogens; Cell Transformation, Neoplastic; Colon; Dimethylhydrazines; Male; Neoplastic Stem Cells; Rats; Rats, Inbred F344

2009
Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression.
    Experimental & molecular medicine, 2009, Oct-31, Volume: 41, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Dimethylhydrazines; Diterpenes; Epoxy Compounds; Humans; Interleukin-6; Janus Kinases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Neoplasm Transplantation; Phenanthrenes; rac1 GTP-Binding Protein; Signal Transduction; STAT3 Transcription Factor; Tumor Burden

2009
Chemopreventive effect of different ratios of fish oil and corn oil in experimental colon carcinogenesis.
    Lipids, 2010, Volume: 45, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Corn Oil; Dimethylhydrazines; Fish Oils; Male; Rats; Rats, Wistar; Reactive Oxygen Species

2010
PTEN regulates apoptotic cell death through PI3-K/Akt/GSK3β signaling pathway in DMH induced early colon carcinogenesis in rat.
    Experimental and molecular pathology, 2012, Volume: 93, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Dimethylhydrazines; Drug Therapy, Combination; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Membrane Potential, Mitochondrial; Phosphatidylinositol 3-Kinase; Phycocyanin; Piroxicam; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2012
Frequency of proliferation, apoptosis, and their ratio during rat colon carcinogenesis and their characteristic pattern in the dimethylhydrazine-induced colon adenoma and carcinoma.
    Cancer investigation, 2002, Volume: 20, Issue:5-6

    Topics: Adenoma; Animals; Apoptosis; Carcinogens; Carcinoma; Cell Division; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Humans; Male; Rats; Rats, Wistar

2002
Effect of chronic dietary ethanol consumption on colonic cancer in rats induced by 1,1-dimethylhydrazine.
    Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:1 Suppl

    Topics: Alcoholism; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Dimethylhydrazines; Ethanol; Intestinal Mucosa; Liver; Rats; Rats, Wistar

2007
Requirement of cell proliferation for the induction of presumptive preneoplastic lesions in rat liver by a single dose of 1,2-dimethylhydrazine.
    Chemico-biological interactions, 1980, Volume: 32, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Choline Deficiency; Dimethylhydrazines; gamma-Glutamyltransferase; Hepatectomy; Liver; Male; Methylhydrazines; Rats

1980
Genesis of 1,2-dimethylhydrazine-induced colon cancer. A light and electron microscopic study.
    Archives of pathology & laboratory medicine, 1981, Volume: 105, Issue:1

    Topics: Adenocarcinoma, Mucinous; Animals; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Female; Intestinal Mucosa; Male; Microscopy, Electron; Neoplasms, Experimental; Precancerous Conditions; Rats

1981
Stimulation of rat colonic crypt cell proliferative activity by wheat bran consumption during the stage of 1,2-dimethylhydrazine administration.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: 1,2-Dimethylhydrazine; Animals; Cell Division; Cell Transformation, Neoplastic; Colon; Dietary Fiber; Dimethylhydrazines; Intestinal Mucosa; Male; Methylhydrazines; Rats; Rats, Inbred Strains; Triticum

1984
[Kinetic characteristics of the normal enterocyte population and in carcinogenesis].
    Tsitologiia, 1984, Volume: 26, Issue:7

    Topics: 1,2-Dimethylhydrazine; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Dimethylhydrazines; Female; Intestinal Neoplasms; Intestine, Large; Kinetics; Mice; Mice, Inbred BALB C; Mitosis; Rats; Time Factors

1984
Early histopathologic events to evolution of colon cancer in C57BL/6 and CF1 mice treated with 1,2-dimethylhydrazine.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Colon; Colonic Neoplasms; Dimethylhydrazines; DNA; Histocytochemistry; Kinetics; Methylhydrazines; Mice; Mice, Inbred Strains; Mitotic Index; Mucins; Neoplasms, Experimental; Time Factors

1983
Cell proliferation in gastrointestinal carcinogenesis.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 104

    Topics: Animals; Autoradiography; Cell Division; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dimethylhydrazines; Gastric Mucosa; Gastrointestinal Neoplasms; Humans; Hyperplasia; Intestinal Mucosa; Mice; Rats; Thymidine; Time Factors; Tritium

1984
A scanning electron microscopy study of changes in the colonic mucus layer during chemical carcinogenesis.
    Cancer, 1983, May-15, Volume: 51, Issue:10

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Female; Intestinal Mucosa; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains

1983
Cloning and screening of sequences expressed in a mouse colon tumor.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Clone Cells; Colonic Neoplasms; Dimethylhydrazines; Gene Expression Regulation; Hybrid Cells; Kidney; Kinetics; Liver; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Plasmids

1982
Degenerative behavior of epithelial cells in the colonic crypt of the mouse following administration of colonic carcinogen, 1,2-dimethylhydrazine.
    Cancer letters, 1981, Volume: 13, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Colon; Dimethylhydrazines; DNA; Epithelium; Female; Methylhydrazines; Mice

1981
Calcium regulation of colonic crypt cell kinetics: evidence for a direct effect in mice.
    Gastroenterology, 1995, Volume: 109, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Calcium; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet, Fat-Restricted; Dimethylhydrazines; Female; Mice; Mice, Inbred Strains

1995
Initiated stem cells in murine intestinal carcinogenesis: prolonged survival, control by NK cells, and progression.
    International journal of cancer, 1994, Nov-15, Volume: 59, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Brunner Glands; Cell Survival; Cell Transformation, Neoplastic; Dimethylhydrazines; Duodenal Neoplasms; G(M1) Ganglioside; Hyperplasia; Killer Cells, Natural; Male; Mice; Mice, Inbred Strains; Mitosis; Neoplastic Stem Cells; Poly I-C

1994
Relationship between dose, time, and tumor yield in mouse dimethylhydrazine-induced colon tumorigenesis.
    Cancer letters, 1979, Volume: 8, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Female; Methylhydrazines; Neoplasms, Experimental; Rectal Neoplasms; Time Factors

1979
Histogenesis of symmetrical 1,2-dimethylhydrazine-induced neoplasms of the colon in the mouse.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Female; Hyperplasia; Intestinal Mucosa; Methylhydrazines; Mice; Neoplasms, Experimental; Precancerous Conditions; Time Factors

1978
[Ultrastructure study of the preneoplastic colon (carcinogenesis with 1,2-dimethylhydrazine)].
    Annales d'anatomie pathologique, 1978, Volume: 23, Issue:4-5

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dimethylhydrazines; Microscopy, Electron; Neoplasms, Experimental; Precancerous Conditions; Rats; Time Factors

1978
Preneoplastic changes in rabbit pancreatic duct cells produced by dimethylhydrazine.
    International journal of cancer, 1975, Nov-15, Volume: 16, Issue:5

    Topics: Adenoma; Animals; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Dimethylhydrazines; Hydrazines; Hyperplasia; Metaplasia; Necrosis; Pancreatic Ducts; Pancreatic Neoplasms; Precancerous Conditions; Rabbits; Time Factors

1975
Selective synthesis and accumulation of nuclear non-histone proteins during carcinogenesis of the colon induced by 1, 2-dimethylhydrazine.
    Cancer, 1975, Volume: 36, Issue:6 Suppl

    Topics: Amino Acids; Animals; Cell Nucleus; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Epithelium; Hydrazines; Leucine; Male; Neoplasm Proteins; Neoplasms, Experimental; Nucleoproteins; Rats

1975
[Proliferative activity of the epithelium of the rat large intestine during carcinogenesis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1976, Volume: 81, Issue:1

    Topics: Adenocarcinoma; Animals; Carcinoma in Situ; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Mitosis; Rats

1976
Changes in nuclear non-histone protein composition during normal differentiation and carcinogenesis of intestinal epithelial cells.
    Experimental cell research, 1976, Mar-15, Volume: 98, Issue:2

    Topics: Animals; Cell Differentiation; Cell Fractionation; Cell Nucleus; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; DNA; Histones; Intestinal Mucosa; Male; Neoplasms, Experimental; Nucleoproteins; Rats; RNA

1976
Biochemical changes in preneoplastic rodent intestines.
    Cancer research, 1976, Volume: 36, Issue:7 PT 2

    Topics: 2-Acetylaminofluorene; Age Factors; Animals; Carboxy-Lyases; Cell Transformation, Neoplastic; Dimethylhydrazines; Intestinal Neoplasms; Intestines; Ornithine Decarboxylase; Precancerous Conditions; Rats; Thymidine Kinase; Time Factors

1976
[Animal experiment studies of carcinogen-induced tumor development in colotomies in relation to suture materials].
    Langenbecks Archiv fur Chirurgie, 1992, Volume: 377, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dimethylhydrazines; Nickel; Polyglactin 910; Rats; Risk Factors; Surgical Staplers; Sutures

1992
Long-term explant culture of human colon and a 3-step transformation model for rat colonic epithelium.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1991, Volume: 59, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Colon; Dimethylhydrazines; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Humans; Injections, Intramuscular; Intestinal Mucosa; L-Lactate Dehydrogenase; Male; Mice; Mice, Nude; Organ Culture Techniques; Rats; Rats, Inbred Strains; Sarcoma Viruses, Murine; Time Factors; Transplantation, Heterologous

1991
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
    Toxicologic pathology, 1991, Volume: 19, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylhydrazines; Lung Neoplasms; Methylcholanthrene; Methylnitrosourea; Mice; Mice, Inbred A; Microscopy, Electron; Nitrosamines

1991
Changes in the activities of jejunal glucosidases in experimental intestinal tumorigenesis induced by 1,2 dimethylhydrazine in rats fed different diets.
    Experimental pathology, 1991, Volume: 42, Issue:3

    Topics: 1,2-Dimethylhydrazine; Administration, Oral; alpha-Glucosidases; Animals; beta-Galactosidase; Carbohydrate Metabolism; Carcinogens; Cell Transformation, Neoplastic; Diet; Dietary Fats; Dimethylhydrazines; Glucosidases; Hydrolysis; Injections, Subcutaneous; Intestinal Mucosa; Jejunal Neoplasms; Jejunum; Lactase; Male; Rats; Sucrase

1991
Mutations in the K-ras oncogene induced by 1,2-dimethylhydrazine in preneoplastic and neoplastic rat colonic mucosa.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Base Sequence; Cell Transformation, Neoplastic; Codon; Colonic Neoplasms; Dimethylhydrazines; DNA; Genes, ras; Intestinal Mucosa; Male; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Polymerase Chain Reaction; Precancerous Conditions; Rats

1991
Down-regulation of protein kinase C activity in 1,2-dimethylhydrazine-induced rat colonic tumors.
    Biochimica et biophysica acta, 1991, Mar-19, Volume: 1092, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Cell Membrane; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytosol; Diglycerides; Dimethylhydrazines; Down-Regulation; Intestinal Mucosa; Protein Kinase C; Rats

1991
Lectin-binding sites in neoplastic and non-neoplastic colonic mucosa of 1,2-dimethylhydrazine-treated rats.
    Laboratory investigation; a journal of technical methods and pathology, 1989, Volume: 61, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dimethylhydrazines; Fluorescent Antibody Technique; Glycoconjugates; Intestinal Mucosa; Lectins; Methylhydrazines; Rats; Rats, Inbred Strains

1989
Identification of environmental carcinogens utilizing T-cell mediated immunity.
    Medical hypotheses, 1986, Volume: 19, Issue:3

    Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Asbestos; Carcinogens, Environmental; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Dimethylhydrazines; Dose-Response Relationship, Radiation; Environmental Exposure; Humans; Hydrocarbons, Halogenated; Immunity, Cellular; Intestinal Neoplasms; Mathematics; Neoplasms; Neoplasms, Radiation-Induced; Radioisotopes; Risk; T-Lymphocytes

1986
Effect of activity-stress on experimental rat colon carcinogenesis: early histopathologic changes and colon tumor induction.
    Cancer detection and prevention, 1988, Volume: 13, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Male; Rats; Rats, Inbred Strains; Stress, Psychological

1988
Early mucosal changes in dimethylhydrazine-induced colonic carcinogenesis in rats.
    The Japanese journal of surgery, 1986, Volume: 16, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Cytophotometry; Dimethylhydrazines; DNA, Neoplasm; Epithelium; Intestinal Mucosa; Precancerous Conditions; Rats

1986
Effects of immunostimulation with OK432, coenzyme Q10, or levamisole on dimethylhydrazine-induced colonic carcinogenesis in rats.
    The Japanese journal of surgery, 1986, Volume: 16, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Biological Products; Cell Transformation, Neoplastic; Coenzymes; Colonic Neoplasms; Dimethylhydrazines; Epithelium; Intestinal Mucosa; Levamisole; Picibanil; Rats; Ubiquinone

1986
Experimental colitis and colonic cancer in the rat.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Cell Transformation, Neoplastic; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Precancerous Conditions; Rats; Rats, Inbred Strains

1985
Adrenergic factors regulating cell division in the colonic crypt epithelium during carcinogenesis and in colonic adenoma and adenocarcinoma.
    British journal of cancer, 1985, Volume: 52, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Cell Division; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Mice; Sympathectomy, Chemical; Sympatholytics; Sympathomimetics

1985
A comparative study of dimethylhydrazine regioisomers and the methylazoxymethanol metabolite of 1,1- and 1,2-dimethylhydrazine in relation to transformation in human fibroblasts.
    Cancer letters, 1985, Volume: 29, Issue:3

    Topics: 1,2-Dimethylhydrazine; Azo Compounds; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylhydrazines; DNA; Fibroblasts; Humans; Methylation; Methylazoxymethanol Acetate; Methylhydrazines

1985