dimethylhydrazines has been researched along with Adenocarcinoma, Basal Cell in 253 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 178 (70.36) | 18.7374 |
| 1990's | 69 (27.27) | 18.2507 |
| 2000's | 4 (1.58) | 29.6817 |
| 2010's | 2 (0.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bose, A; Elyagoby, A; Wong, TW | 1 |
| He, B; Liu, Y; Mu, Y; Wu, K; Yang, Q; Zhou, L; Zhou, Q | 1 |
| Jeekel, J; ten Raa, S; van den Tol, MP; van Eijck, CH; van Grevenstein, WM; van Rossen, ME | 1 |
| Barkla, DH; Tutton, PJ | 10 |
| Shimamoto, F; Tahara, E; Yanaihara, N | 1 |
| Chiu, JF; Gootnick, D; Pumo, D | 1 |
| Miyayama, H; Takemiya, M; Takeuchi, T | 2 |
| Aiso, S; Golberg, L; Hirono, I; Ueno, I; Yamaji, T | 1 |
| Martin, MS | 1 |
| Loven, DP; Stevens, RH | 1 |
| Freeman, HJ; Kim, YS; Spiller, GA | 2 |
| Abraham, R; Barbolt, TA; Rodgers, JB | 1 |
| Asp, NG; Bauer, HG; Dahlqvist, A; Fredlund, PE; Nyman, M; Oste, R | 1 |
| Gavin, JB; Herdson, PB; Teague, CA | 1 |
| Fukushima, S; Ito, N; Kurata, Y; Nakanowatari, J; Shirai, T | 1 |
| Jacobs, LR | 1 |
| Czygan, P; Kässmodel, H; Kommerell, B; Raedsch, R; Seitz, HK; Veith, S; Waldherr, R | 1 |
| Dudley, HA; Phillips, RK; Quill, DS | 1 |
| Choluj, B; Hladík, V; Vozenílek, J | 1 |
| Tsukada, K | 1 |
| Howarth, AE; Pihl, E | 1 |
| Bara, J; Burtin, P; Daher, N; Decaëns, C; Rosa, B | 1 |
| King, VP; Lahey, SJ; Madara, J; Munroe, AE; Ravikumar, TS; Ross, DS; Steele, G; Wilson, RE; Wright, D | 1 |
| Andres, ML; Aprecio, RM; Gridley, DS; Kettering, JD; Nutter, RL; Slater, JM | 1 |
| Cole, DA; Stevens, RH | 1 |
| Drago, JR; Joehl, RJ | 1 |
| Kamiya, J; Morioka, Y; Muto, T; Saito, Y | 1 |
| Amodeo, P; Morgenstern, L; Vimadalal, S | 1 |
| Condon, RE; Jones, FE; Komorowski, RA | 1 |
| Böse-Younes, H; Schümann, S; Siegers, CP; Thies, E; Younes, M | 1 |
| Alun, ML; Duvander, A; Nylander, G; Rubio, CA; Sveander, M; Wallin, B | 1 |
| Cheng, HF; Cole, DA; Stevens, RH | 1 |
| Wattenberg, LW | 1 |
| Cole, DA; Meek, ES; Stevens, RH | 1 |
| Corasanti, JG; Hobika, GH; Markus, G | 1 |
| Deasy, J; Harte, P; Lahey, S; Madara, JL; Ross, D; Steele, G | 1 |
| Gedigk, P; Hattori, T; Helpap, B | 1 |
| Mitsuoka, T; Mizutani, T | 1 |
| Fang, WF; Newaz, SN; Strobel, HW | 1 |
| Nylander, G; Rubio, CA; Santos, M | 1 |
| Turusov, VS | 1 |
| Blackman, KE; Diwan, BA | 2 |
| Loven, DP; Oberley, LW; Rousseau, FM; Stevens, RH | 1 |
| Richards, TC | 1 |
| Kowal, EP; Markus, G | 1 |
| Blackman, KE; Diwan, BA; Szakal, AK | 1 |
| Corson, JM; Harte, PJ; King, VP; Madara, J; Munroe, AE; Rayner, AA; Steele, G; Wilson, RE | 1 |
| Clark, CG; Cruse, JP; Lewin, MR | 2 |
| Cowen, DM; Double, JA; Janik, AC; Siegerstetter, J | 1 |
| Hagihara, PF | 1 |
| Krutovskikh, VA; Turusov, VS | 1 |
| Corson, J; Crissey, M; Gittes, R; Harte, P; Steele, G; Wilson, R | 1 |
| Cole, DA; Graves, JM; Loven, DP; Meek, ES; Oberley, L; Rana, RS; Stevens, RH | 1 |
| Harte, PJ; King, VP; Munroe, AE; Rayner, AA; Steele, G; Wilson, RE | 1 |
| Flesher, JW; Goldenberg, DM; Griffen, WO; Hagihara, PF; Hedgecock, H; Ram, MD; Sachatello, CR; Yoneda, K | 1 |
| Blake, JR; Dawson, IM; Hardcastle, JD; Metcalf, MJ; Reeve, RS; Thompson, MJ | 1 |
| Maskens, AP | 2 |
| Klein, B; Klein, T; Madar, Z; Nyska, A; Sheila, N; Weis, O; Zusman, I | 1 |
| Bird, RP | 1 |
| Rubio, CA; Takayama, S | 1 |
| Gershbein, LL | 3 |
| Jagadeesan, V; Rao, NJ; Sesikeran, B | 1 |
| Fukaura, Y; Ishikawa, C; Narisawa, T; Tanida, N; Terada, K; Umezawa, A; Yazawa, K | 1 |
| Cameron, IL; Hardman, WE | 1 |
| Rubio, C; Shetye, J | 1 |
| Hirata, K; Itoh, H; Kuroda, Y; Nagata, N; Ohsato, K | 1 |
| Adams, WJ; Lawson, JA; Morris, DL | 1 |
| Dillehay, DL; Merrill, AH; Schmelz, EM; Webb, SK | 1 |
| Lachowicz, A; Pawlikowski, M; Stepień, H; Szadowska, A; Winczyk, K; Zerek-Mełeń, G | 1 |
| Yasuda, S | 1 |
| Salim, AS | 1 |
| Mori, H; Morishita, Y; Shinoda, T; Tanaka, T | 1 |
| Amir-Mokri, E; Brown, ME; Gershbein, LL; Rezai, VK | 1 |
| Kawaura, A; Nishikawa, M; Shimoyama, T; Takahashi, A; Tanida, N | 1 |
| Clements, BM; McBrearty, FX; von Rueden, DG; Woratyla, S | 1 |
| Bi, S; Geng, BQ; Yong, DG | 1 |
| Brasitus, TA; Davidson, NO; Hausman, AM; Ifkovits, CA; Llor, X; Montag, A; Sitrin, MD; Skarosi, SF | 1 |
| Cameron, IL; Garza, J; Hardman, WE | 1 |
| Chu, CY; Hsu, JD; Tseng, TH; Wang, CJ | 1 |
| Lowe, RM; Mullen, CA; Petropoulos, D | 1 |
| Pan, H; Wu, J; Zheng, S | 1 |
| Adams, J; Dillehay, DL; Merrill, AH; Reiter, A; Schmelz, EM; Webb, SK | 1 |
| Anisimov, VN; Muratov, EI; Popovich, IG | 1 |
| Eggermont, AM; Marquet, RL; Van de Vrie, W | 1 |
| Cameron, IL; Carter, JW; Hardman, WE; Lancaster, H | 1 |
| Alink, GM; Hollanders, VM; Koeman, JH; Rijnkels, JM; Woutersen, RA | 2 |
| Bushnev, AS; Dillehay, DL; Liotta, DC; Merrill, AH; Schmelz, EM | 1 |
| Iwama, T; Kawachi, Y; Kudo, H; Murakami, S; Okayasu, I; Sagara, T; Sakamoto, S; Tsukada, K | 1 |
| Anisimov, VN; Popovich, IG; Zabezhinski, MA | 1 |
| De Bruïne, AP; De Goeij, AF; Song, JY; Van Driel, BE; Van Noorden, CJ | 1 |
| Goodlad, RA; Park, HS; Wright, NA | 1 |
| Fukui, H; Kuriyama, S; Matsumoto, M; Mitoro, A; Nakatani, T; Okamoto, S; Toyokawa, Y; Tsujinoue, H; Yamazaki, M | 1 |
| Brown, SE; Gelroth, JA; Glaser, BK; Ranhotra, GS; Schoening, P | 1 |
| Brown, W; Glare, EM; O'Brien, PE; Vogiagis, D | 1 |
| De Camargo, JL; Montenegro, MR; Rodrigues, MA; Salvadori, DM; Silva, LA | 1 |
| Boerrigter, L; Csikós, T; Dauwerse, H; Demant, P; Groot, PC; Klous, AM; Lindeman, J; Meijjer, GA; Mooi, WJ; Paces, V; Perrakis, A; Ruivenkamp, CA; Scholten, G; Stassen, AP; Tripodis, N; van Ommen, GJ; van Wezel, T; van Zandwijk, N; Vlcek, C; Zanon, C | 1 |
| Fiala, AE; Fiala, ES; Fiala, S; Keller, RW | 1 |
| Chang, WW; Macdonald, PD; Mak, KM | 1 |
| Appleton, DR; Sunter, JP; Watson, AJ; Wright, NA | 1 |
| Malick, L; Toth, B | 1 |
| Habs, M; Schmähl, D; Sych, F | 1 |
| Garmaise, AB; NEWBERNE, PM; Rogers, AE; Sarvaris, CA; Zamcheck, N | 1 |
| Lawson, AJ; Loven, DP; Osborne, JW; Prall, JP; Stevens, RH | 1 |
| Miyoshi, T; Morioka, M; Ohhara, T | 1 |
| Loven, DP; Osborne, JW; Prall, JL; Stevens, RH | 1 |
| Abraham, R; Barbolt, TA | 2 |
| Fujii, I; Hirose, F; Naito, Y; Takizawa, S; Terada, Y; Watanabe, H | 1 |
| Lawson, AJ; Loven, DP; Osborne, JW; Stevens, RH | 1 |
| Bansal, BR; Bansal, SC; Mark, R; Rhoads, JE | 1 |
| Pollard, M; Zedeck, MS | 1 |
| Ashman, LK; Cook, MG; Kotlarski, I | 1 |
| Justrabo, E; Lagneau, A; Martin, F; Martin, MS; Michel, MF | 1 |
| Bowles, ND; Clapp, NK; Klima, WC; Satterfield, LC | 1 |
| Habs, M; Schmähl, D; Wagner, I | 1 |
| Stock, CC; Sugiura, K | 1 |
| Hoffmann, D; Patil, K; Schmeltz, I; Toth, B; Wallcave, L | 1 |
| Chiu, JF; Markert, C; Ong, DE | 1 |
| Chang, WW | 1 |
| Fiala, ES; Wattenberg, LW | 1 |
| Asano, T; Pollard, M | 1 |
| Lindström, CG; Rosengren, JE | 1 |
| Ekberg, O; Lindström, CG; Rosengren, JE | 1 |
| Eichfuss, HP; Werner, B | 1 |
| Chiu, JF; Markert, C; Rogers, LW | 1 |
| Delapierre, F; Laumonier, R; Tayot, J | 1 |
| Hutcheson, DP; Wideman, L; Wilson, RB | 1 |
| Griffin, AC; Jacobs, MM; Jansson, B | 1 |
| de Heer, K; Mitschke, H; Werner, B | 1 |
| Dahm, K; Knipper, A; Mitschke, H | 1 |
| Harris, J; Tompkins, M; Westenberger, P; Winneker, RC | 1 |
| Gushchin, VA; Klimashevskiĭ, VF; Pozharisskiĭ, KM | 1 |
| Reddy, BS; Watanabe, K; Weisburger, JH | 1 |
| Toth, B | 1 |
| Fricks, CM; Moon, RC | 1 |
| Allfrey, VG; Boffa, LC | 1 |
| Malick, L; Shimizu, H; Toth, B | 1 |
| Enker, WE; Jacobitz, JL | 1 |
| Larsson, A; Leandoer, L; Lindström, C; Rosengren, JE; Sjögren, HO; Steele, G | 1 |
| Corbett, TH; Griswold, DP; Peckham, JC; Roberts, BJ; Schabel, FM | 1 |
| Price, MR; Sjögren, HO; Steele, G | 1 |
| Asano, T; Madsen, DC; Pollard, M | 1 |
| Monakhov, NK; Pozharisskiĭ, KM; Shvartsman, AL | 1 |
| Kolodin, VI; Pozharisskiĭ, KM | 1 |
| Pozharisskiĭ, KM | 1 |
| Narisawa, T; Reddy, BS; Vukusich, D; Weisburger, JH; Wynder, EL | 1 |
| Cameron, IL; Hardman, WE; Heitman, DW | 1 |
| Crouch, R; Davis, AE; Patterson, F | 1 |
| Bara, J; Caignard, A; Genne, P; Hammann, A; Martin, F; Olsson, NO; Oriol, R | 1 |
| Geerling, RA; IJzermans, JN; Jeekel, J; Marquet, RL; Scheringa, M; van der Schelling, GP | 1 |
| Dohi, K; Ito, A; Nakagawa, Y; Takahashi, T; Watanabe, H | 1 |
| Craven, PA; DeRubertis, FR | 1 |
| Gershbein, LL; Rao, KC | 1 |
| Beniashvili, DS; Krutovskikh, VA; Sartania, MS; Turusov, VS | 1 |
| Brodin, NT; Jansson, B; Sjögren, HO | 1 |
| Morvay, K; Nawroth, R; Senger, H; Szentléleki, K; Török, G | 1 |
| Berrada, A; Foultier, MT; Patrice, T; Xu, XN; Yactayo, S | 1 |
| Hagino, M; Katou, T; Kohli, Y; Murakita, H; Satou, F; Suzuki, K | 1 |
| O'Brien, PE; Penney, AG; Skinner, SA | 1 |
| Cameron, IL; Contreras, E; Hardman, WE; Heitman, DW | 1 |
| Rivera, F; Rubio, CA | 1 |
| Daugherty, JP; Fanning, J; Keidan, RD; Weese, JL | 1 |
| Colony, PC; McGarrity, TJ; Peiffer, LP | 2 |
| Hirose, M; Ito, N; Kamano, K; Masuda, A; Okuyama, H | 1 |
| Kasahara, N; Kato, T; Kawachi, Y; Kawasaki, T; Kudo, H; Kuwa, K; Okamoto, R; Sagara, T; Sakamoto, S; Tominaga, S | 1 |
| Ho, YS; Jao, SW; Lee, W | 1 |
| Shibusawa, M; Takimoto, M; Tsunoda, A | 1 |
| Blinova, GA; Mikheev, AM; Napalkov, NP | 1 |
| Behling, AR; Choquette, LL; Greger, JL; Kaup, SM | 1 |
| Beck, N; Buhr, HJ; Hupp, T | 1 |
| Brasitus, TA; Chowdhury, LN; Davidson, NO; Dudeja, PK; Halline, AG; Jacoby, RF; Llor, X; Teng, BB | 1 |
| Boivin, Y; Brais, MF; Carioto, S; De Zubiria, M; Durh, MA; Heppell, J; Potvin, C | 1 |
| Billings, PC; Carew, JA; Keller-McGandy, C; Kennedy, AR; Newberne, P; St Clair, WH | 1 |
| O'Brien, PE; Skinner, SA; Tutton, PJ | 1 |
| Bounous, G; Fleiszer, D; Gold, P; Papenburg, R | 1 |
| Beniashvili, DSh; Krutovskikh, VA; Sartaniia, MS; Sharashidze, LK; Turkiia, NG; Turusov, VS | 1 |
| Chester, JF; Gaissert, HA; Malt, RA; Ross, JS; Weitzman, SA | 1 |
| Duvander, A; Rubio, CA; Sveander, M; Wallin, B; Ware, J | 1 |
| Mehta, T; Roberts-Andersen, J; Wilson, RB | 1 |
| Kolár, Z; Lichnovský, V | 1 |
| Wang, CG; Wang, JF; Wang, JP | 1 |
| Cocchiaro, C; D'Emilia, J; King, V; Ravikumar, TS; Steele, G; Wolf, B | 1 |
| Brasitus, TA; Dudeja, PK; Halline, AG | 1 |
| Arakawa, S; Ishihara, H; Tejima, S; Wakazono, H | 1 |
| Jansa, P; Kolár, Z; Pastrnák, A | 2 |
| Nauss, KM; Rogers, AE | 1 |
| Jacobs, LR; Lupton, JR | 1 |
| Brasitus, TA; Dahiya, R; Dudeja, PK | 1 |
| Khoobyarian, N; Nelson, RL; Samelson, SL; Wilson, W | 1 |
| Caignard, A; Kitagawa, Y; Nagao, M; Sato, S | 1 |
| Balzer, T; Gutschmidt, S; Heimpel, S; Riecken, EO; Sandforth, F | 1 |
| Appleton, DR; Finney, KJ; Ince, P; Moorghen, M; Sunter, JP; Watson, AJ | 1 |
| Li, Y; Oberley, LW; Sun, Y | 1 |
| Abourachid, H; Bara, J; Daher, N; Decaens, C; Gautier, R | 1 |
| Ahnen, DJ; Brown, WR; Sugiyama, T | 1 |
| Li, Y; Sun, Y | 1 |
| Galloway, P; Gerson, SL; Gordon, N; Hawkins, N; Hull, CC; Stellato, TA | 1 |
| Lamote, J; Willems, G | 1 |
| Reddy, BS; Tanaka, T | 1 |
| Buddingh, F; Pence, BC; Yang, SP | 1 |
| Amodeo, D; Lee, S; Quaroni, A; Weiser, MM | 1 |
| Maruyama, H; Reddy, BS | 1 |
| Basu, TK; Temple, NJ | 1 |
| Lafreniere, R; Rosenberg, SA | 1 |
| Bykorez, AI; Garmanchuk, LV; Gut, IT; Ivashchenko, IuD; Osipova, LA | 1 |
| Kameda, T; Oda, N; Sumiyoshi, H; Tahara, E; Tanaka, T; Yamamoto, T; Yasui, W | 1 |
| Cobb, RA; Garrod, DR; Gartell, PC; Steer, HW; Suhrbier, A | 1 |
| Gilbert, JM | 1 |
| Erdösová, B; Kolár, Z | 1 |
| Bueche, D; Nauss, KM; Newberne, PM | 1 |
| el-Khatib, SM; Temple, NJ | 1 |
| Agrez, MV; House, AK; Jenkyn, DJ; Maley, MA | 1 |
| Andrianopoulos, G; Nelson, RL; Tanure, JC | 1 |
| Amberger, H | 1 |
| Alun, ML; Duvander, A; Nylander, G; Rubio, CA; Sveander, M; Wahlin, B | 1 |
| Bibby, MC; Double, JA | 1 |
| Saito, Y | 1 |
| Dorofeev, GI; Ivashkin, VT; Romanov, VV; Sultanov, VK; Vasil'ev, VIu | 1 |
| Katsura, Y; Maruyama, J; Matsuda, T; Ogawa, M; Yasutomi, M | 1 |
| Buchanan, KD; Johnston, CF; O'Hare, MM; O'Neill, AB | 1 |
| Brasitus, TA; Brown, MD; Dahiya, R; Dudeja, PK | 1 |
| Wargovich, MJ | 1 |
| Czygan, P; Kommerell, B; Raedsch, R; Seitz, HK; Simanowski, U; Veith, S; Waldherr, R | 1 |
| Boffa, LC; Bolognesi, C | 1 |
| Alun, ML; Duvander, A; Nylander, G; Rubio, CA; Sveander, M | 1 |
| Chiu, JF; Gabryelak, T; Kim, Y; Wen, BG | 1 |
| Kaufmann, P; Locniskar, M; Nauss, KM; Newberne, PM | 1 |
| Barkla, DH; Kennedy, MF; Tutton, PJ | 1 |
| Demura, H; Demura, R; Jibiki, K; Kato, Y; Nakamura, S; Oda, S; Odagiri, E | 1 |
| Sumiyoshi, H | 1 |
| Abe, O; Ishimura, Y; Kodaira, S; Okuda, K; Sadahiro, S; Takahashi, T; Takami, H | 1 |
| Dushkin, VA; Podoprigora, GI; Pozharisskiĭ, KM | 1 |
3 review(s) available for dimethylhydrazines and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Role of aberrant crypt foci in understanding the pathogenesis of colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Genes, ras; Humans; Intestinal Mucosa; Precancerous Conditions | 1995 |
Nitrogen intake and tumorigenesis in rats.
Topics: Adenocarcinoma; Ammonia; Animals; Caseins; Dietary Fats; Dietary Proteins; Dimethylhydrazines; Dose-Response Relationship, Drug; Ear Neoplasms; Hydrazines; Intestinal Neoplasms; Rats; Urea | 1977 |
Gastrointestinal tumours after stapler vs vicryl anastomoses in carcinogen-treated rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Neoplasm Recurrence, Local; Nickel; Polyglactin 910; Rats; Surgical Staplers; Suture Techniques; Sutures | 1990 |
1 trial(s) available for dimethylhydrazines and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Injection of recombinant tumor necrosis factor directly into liver metastases: an experimental and clinical approach.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adult; Aged; Animals; Carcinogens; Colitis, Ulcerative; Colonic Neoplasms; Dimethylhydrazines; Drug Evaluation; Drug Screening Assays, Antitumor; Feasibility Studies; Female; Humans; Injections, Intralesional; Liver Neoplasms; Male; Middle Aged; Rats; Rats, Inbred Strains; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
249 other study(ies) available for dimethylhydrazines and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Oral 5-fluorouracil colon-specific delivery through in vivo pellet coating for colon cancer and aberrant crypt foci treatment.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Adenoma; Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biological Availability; Cellulose; Chemistry, Pharmaceutical; Colonic Neoplasms; Dimethylhydrazines; Drug Delivery Systems; Feasibility Studies; Female; Fluorouracil; Pectins; Powders; Rats, Sprague-Dawley; Solubility; Tablets, Enteric-Coated; Technology, Pharmaceutical; Tumor Burden | 2014 |
Berberine inhibits the proliferation of colon cancer cells by inactivating Wnt/β-catenin signaling.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; beta Catenin; Caspase 3; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dextran Sulfate; Dimethylhydrazines; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression; Genes, Reporter; HCT116 Cells; Humans; Luciferases, Firefly; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway | 2012 |
The post-surgical inflammatory response provokes enhanced tumour recurrence: a crucial role for neutrophils.
Topics: Acute-Phase Reaction; Adenocarcinoma; Animals; Cell Count; Dimethylhydrazines; Disease Models, Animal; Female; Inflammation; Laparotomy; Lymphocytes; Neoplasm Recurrence, Local; Neoplasm Seeding; Neutrophils; Peritoneal Neoplasms; Rats; Rats, Inbred Strains | 2007 |
Effects of glucocorticoid hormones on cell proliferation in dimethylhydrazine-induced tumours in rat colon.
Topics: Adenocarcinoma; Adrenalectomy; Animals; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Glucocorticoids; Male; Rats | 1981 |
The influence of androgens, anti-androgens, and castration on cell proliferation in the jejunal and colonic crypt epithelia, and in dimethylhydrazine-induced adenocarcinoma of rat colon.
Topics: Adenocarcinoma; Anilides; Animals; Castration; Cell Division; Colon; Colonic Neoplasms; Dimethylhydrazines; Flutamide; Intestinal Mucosa; Jejunum; Male; Rats; Testosterone | 1982 |
Gut endocrine cells in rat intestinal-tract carcinoma induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Chromaffin System; Dimethylhydrazines; Enterochromaffin Cells; Female; Gastrins; Glucagon-Like Peptides; Intestinal Neoplasms; Male; Microscopy, Electron; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Somatostatin; Vasoactive Intestinal Peptide | 1983 |
Antigenic changes in nuclear chromatin in 1,2-dimethylhydrazine-induced colon carcinogenesis.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Chromatin; Colonic Neoplasms; Dimethylhydrazines; Epitopes; Male; Methylhydrazines; Neoplasms, Experimental; Precancerous Conditions; Rats; Time Factors | 1980 |
Pathogenesis of 1,2-dimethylhydrazine-induced carcinomas in rat intestine. II. Histochemical and ultrastructural characteristics of glycoproteins of 1,2-dimethylhydrazine-induced carcinoma cells.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Dimethylhydrazines; Glycoproteins; Histocytochemistry; Intestinal Mucosa; Intestinal Neoplasms; Intestines; Male; Methylhydrazines; Microscopy, Electron; Mucins; Rats; Rats, Inbred Strains; Staining and Labeling; Tissue Distribution | 1982 |
Enhancing effect of dextran sulfate sodium on colorectal carcinogenesis by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Animals; Cocarcinogenesis; Colonic Neoplasms; Dextran Sulfate; Dextrans; Dimethylhydrazines; Male; Methylhydrazines; Molecular Weight; Rats; Rats, Inbred ACI; Rectal Neoplasms | 1983 |
[Contribution of experimental carcinogenesis to the pathogenesis of colorectal cancer in man].
Topics: Adenocarcinoma; Adenoma; Animals; Cholecystectomy; Cocarcinogenesis; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Humans; Mice; Rats | 1984 |
Intracellular adenosine and guanosine 3',5'-cyclic monophosphate concentrations in rat small and large bowel following single and multiple exposures to 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; Dimethylhydrazines; Injections, Subcutaneous; Intestinal Neoplasms; Kinetics; Male; Precancerous Conditions; Rats | 1980 |
A double-blind study on the effects of differing purified cellulose and pectin fiber diets on 1,2-dimethylhydrazine-induced rat colonic neoplasia.
Topics: Adenocarcinoma; Animals; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Male; Neoplasms, Experimental; Pectins; Rats | 1980 |
Inhibition by bran of the colonic cocarcinogenicity of bile salts in rats given dimethylhydrazine.
Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Carcinoma; Cellulose; Cocarcinogenesis; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Duodenal Neoplasms; Male; Methylhydrazines; Neoplasms, Experimental; Rats | 1980 |
Effect of two kinds of pectin and guar gum on 1,2-dimethylhydrazine initiation of colon tumors and on fecal beta-glucuronidase activity in the rat.
Topics: Adenocarcinoma; Animals; Bacteria; Body Weight; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Feces; Glucuronidase; Male; Methylhydrazines; Pectins; Rats | 1981 |
The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Dimethylhydrazines; Ear Canal; Ear Neoplasms; Hemangiosarcoma; Intestinal Neoplasms; Liver Neoplasms; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
Pathogenesis of 1,2-dimethylhydrazine-induced carcinomas in rat intestine. I. The induction of mucin producing carcinomas in rat intestine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Cecal Neoplasms; Colonic Neoplasms; Dimethylhydrazines; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Male; Methylhydrazines; Mucins; Rats; Rats, Inbred Strains | 1982 |
Different dose-response relationships in the induction of different types of colonic tumors in Wistar rats by 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Enhancement of rat colon carcinogenesis by wheat bran consumption during the stage of 1,2-dimethylhydrazine administration.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Drug Synergism; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Triticum | 1983 |
Enhancement of 1,2-dimethylhydrazine-induced rectal carcinogenesis following chronic ethanol consumption in the rat.
Topics: Adenocarcinoma; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Bile Acids and Salts; Diet; Dimethylhydrazines; Ethanol; Feces; Intestinal Polyps; Male; Methylhydrazines; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1984 |
Experimental colon neoplasia enhanced by extract of sperm (protamine).
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Colonic Polyps; Dimethylhydrazines; Female; Fluorouracil; Heparin; Male; Protamines; Rats; Rats, Inbred Strains; Spermatozoa | 1984 |
[An experimental model of cancer of the large intestine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Cholestyramine Resin; Colonic Neoplasms; Dimethylhydrazines; Female; Mice; Neoplasms, Experimental; Rectal Neoplasms | 1984 |
[Thymidine kinase isozyme in DMH-induced colon tumor in rats].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Isoenzymes; Male; Rats; Rats, Inbred Strains; Thymidine Kinase | 1984 |
High-fat diet promotes and causes distal shift of experimental rat colonic cancer--beer and alcohol do not.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Alcohol Drinking; Animals; Beer; Carcinogens; Colonic Neoplasms; Diet; Dietary Fats; Dimethylhydrazines; Ethanol; Male; Rats; Rats, Inbred Strains | 1984 |
Effect of 13 cis retinoic acid on early precancerous antigenic goblet-cell modifications and induction of cancer during 1,2-dimethylhydrazine carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Intestinal Neoplasms; Isotretinoin; Methylhydrazines; Neoplasm Metastasis; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred Strains; Tretinoin | 1983 |
Effects of specific active immunization on tumor recurrence following primary tumor resection in WF rats with 1,2-dimethylhydrazine-induced bowel cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Immunotherapy; Male; Neoplasm Recurrence, Local; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1984 |
Modification of a transplantable colon tumor and immune responses in mice fed different sources of protein, fat and carbohydrate.
Topics: Adenocarcinoma; Animals; Antibody-Dependent Cell Cytotoxicity; Colonic Neoplasms; Dextrins; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Dimethylhydrazines; Immunity, Cellular; Killer Cells, Natural; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Milk Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phytohemagglutinins; Spleen; Sucrose; T-Lymphocytes | 1983 |
Identification of carcinogens by measurement of cell-mediated immunity. IV. Antitumor immunity following perinatal exposure to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Cytotoxicity, Immunologic; Dimethylhydrazines; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Female; Fetus; Immunity, Cellular; Lymphocytes; Maternal-Fetal Exchange; Methylhydrazines; Pregnancy; Rats; Rats, Inbred F344 | 1983 |
Experimental cancer of the bowel in the Nb rat.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Female; Intestinal Polyps; Neoplasms, Experimental; Rats | 1983 |
[Strain differences in susceptibility of rat colon to 1,2-dimethyl-hydrazine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Methylhydrazines; Rats; Rats, Inbred Strains; Species Specificity | 1983 |
Effects of choledochojejunostomy with Roux-en-Y exclusion on dimethylhydrazine induced neoplasms in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Bile; Colonic Neoplasms; Common Bile Duct; Dimethylhydrazines; Female; Intestinal Neoplasms; Jejunum; Methods; Methylhydrazines; Rats; Rats, Inbred Strains | 1984 |
The effects of ascorbic acid and butylated hydroxyanisole in the chemoprevention of 1,2-dimethylhydrazine-induced large bowel neoplasms.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Administration, Oral; Animals; Anisoles; Ascorbic Acid; Butylated Hydroxyanisole; Colonic Neoplasms; Diet; Dimethylhydrazines; Female; Mice | 1984 |
Aldrin epoxidase and dimethylhydrazine demethylase activities in tumorous and non-tumorous tissue of the human colon and rectum.
Topics: Adenocarcinoma; Aldrin; Biotransformation; Colonic Neoplasms; Dimethylhydrazines; Epoxide Hydrolases; Female; Humans; Intestinal Mucosa; Liver; Male; Oxidoreductases, N-Demethylating; Rectal Neoplasms | 1984 |
Carcinogenesis at colonic anastomotic sites. An animal study.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Intestinal Mucosa; Male; Neoplasm Recurrence, Local; Rats; Rats, Inbred Strains; Sutures | 1984 |
Identification of a common oncofoetal protein in x-ray and chemically induced rat gastrointestinal tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antigens, Neoplasm; Dimethylhydrazines; Gastrointestinal Neoplasms; Immunodiffusion; Immunoelectrophoresis; Liver; Lung; Male; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Rats | 1981 |
Inhibition of carcinogen-induced neoplasia by sodium cyanate, tert-butyl isocyanate, and benzyl isothiocyanate administered subsequent to carcinogen exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Benz(a)Anthracenes; Cyanates; Dimethylhydrazines; Female; Intestinal Neoplasms; Isocyanates; Isothiocyanates; Mammary Neoplasms, Experimental; Methylhydrazines; Mice; Neoplasms, Experimental; Rats; Thiocyanates; Time Factors | 1981 |
Antibody-dependent cell cytotoxicity in chemical-induced rat pancreas and colon cancer.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antibody-Dependent Cell Cytotoxicity; Colonic Neoplasms; Dimethylhydrazines; Male; Neoplasms, Experimental; Pancreatic Neoplasms; Rats; Rats, Inbred F344 | 1981 |
Interference with dimethylhydrazine induction of colon tumors in mice by epsilon-aminocaproic acid.
Topics: Adenocarcinoma; Aminocaproates; Animals; Colonic Neoplasms; Dimethylhydrazines; Female; Male; Methylhydrazines; Mice; Neoplasms, Experimental; Plasminogen; Plasminogen Activators; Plasminogen Inactivators; Protein Binding | 1982 |
Evidence for an adenoma-carcinoma sequence in dimethylhydrazine-induced neoplasms of rat intestinal epithelium.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Dimethylhydrazines; Gastrointestinal Neoplasms; Intestinal Mucosa; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred WF | 1983 |
Development and cell kinetics of colonic tumors induced in mice by dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Autoradiography; Carcinoma; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Male; Methylhydrazines; Mice; Mice, Inbred Strains; Neoplasms, Experimental | 1983 |
Effect of Konjac mannan on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Intestinal Neoplasms; Intestine, Small; Male; Mannans; Methylhydrazines; Neoplasms, Experimental; Polysaccharides; Rats; Rats, Inbred F344 | 1983 |
Metabolism of the carcinogen 1,2-dimethylhydrazine by isolated human colon microsomes and human colon tumor cells in culture.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adult; Biotransformation; Carcinogens; Cells, Cultured; Colon, Sigmoid; Colonic Neoplasms; Dimethylhydrazines; Female; Humans; Hydrocortisone; Intestinal Mucosa; Male; Methylhydrazines; Middle Aged; Mixed Function Oxygenases; Phenobarbital | 1983 |
Experimental colon cancer in the absence of intestinal contents in Sprague-Dawley rats.
Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Colon; Colonic Neoplasms; Dimethylhydrazines; Neoplasms, Experimental; Rats | 1980 |
Morphology and histogenesis of anal region and clitoral gland tumors induced in mice by 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Adenoma; Anal Gland Neoplasms; Animals; Carcinoma, Squamous Cell; Clitoris; Dimethylhydrazines; Female; Genital Neoplasms, Female; Methylhydrazines; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Neoplasms, Experimental; Sebaceous Gland Neoplasms | 1980 |
Carcinogenic effects of combined treatment of inbred mice with 3-methylcholanthrene and 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Drug Interactions; Leukemia, Experimental; Lung Neoplasms; Methylcholanthrene; Methylhydrazines; Mice; Mice, Inbred Strains; Neoplasms, Experimental | 1980 |
Superoxide dismutase activity in 1,2-dimethylhydrazine-induced rat colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Male; Neoplasms, Experimental; Nitroblue Tetrazolium; Rats; Superoxide Dismutase | 1980 |
Changes in crypt cell populations of mouse colon during recovery from treatment with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Drug Administration Schedule; Female; Hyperplasia; Intestinal Mucosa; Methylhydrazines; Mice; Neoplasms, Experimental; Precancerous Conditions; Time Factors | 1981 |
Kinetic properties of thymidine kinase from the cytosol of a rat colon adenocarcinoma.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Cytosol; Dimethylhydrazines; Female; Kinetics; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thymidine Kinase | 1982 |
Modulation of immunological competence in 1,2-dimethylhydrazine-sensitive SWR/J mice during colorectal carcinogenesis.
Topics: Adenocarcinoma; Animals; B-Lymphocytes; Colonic Neoplasms; Dimethylhydrazines; Hyperplasia; Immunocompetence; Male; Methylhydrazines; Mice; Neoplasm Invasiveness; Rectal Neoplasms; T-Lymphocytes; Time Factors | 1980 |
The effect of adjuvant immunotherapy on tumor recurrence after segmental resection of carcinogen-induced Wistar/Furth primary bowel adenocarcinomas.
Topics: Adenocarcinoma; Animals; Dimethylhydrazines; Immunization; Intestinal Neoplasms; Male; Neoplasm Transplantation; Rats; Rats, Inbred WF; Recurrence | 1982 |
Dietary cholesterol deprivation improves survival and reduces incidence of metastatic colon cancer in dimethylhydrazine-pretreated rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cholesterol, Dietary; Colonic Neoplasms; Dimethylhydrazines; Female; Neoplasms, Experimental; Rats | 1982 |
The assessment of response of murine transplantable colon tumors to combination chemotherapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carmustine; Cell Line; Colonic Neoplasms; Dimethylhydrazines; Drug Therapy, Combination; Fluorouracil; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Semustine | 1982 |
Experimental colitis as a promoter in large-bowel tumorigenesis.
Topics: 1,2-Dimethylhydrazine; Acetates; Adenocarcinoma; Adenoma; Animals; Colitis; Colonic Neoplasms; Dimethylhydrazines; Disease Susceptibility; Enema; Intestinal Mucosa; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1982 |
[Morphogenesis of experimental cancer of the large intestine (according to the results of scanning electron and light microscopy)].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Hybridization, Genetic; Hyperplasia; Intestinal Polyps; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microscopy, Electron, Scanning; Rats | 1982 |
Potentiation of dimethylhydrazine bowel carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinoma, Transitional Cell; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; FANFT; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms; Urinary Diversion | 1981 |
Evidence for a defective mitochondrial membrane in 1,2-dimethylhydrazine-induced colon adenocarcinoma in rat: enhanced lipid peroxidation potential in vitro.
Topics: Adenocarcinoma; Animals; Cell Membrane; Colonic Neoplasms; Dimethylhydrazines; Lipid Peroxides; Male; Mitochondria; Rats | 1980 |
Effect of major small bowel resection on dimethylhydrazine-induced bowel carcinogenesis.
Topics: Adenocarcinoma; Animals; Cocarcinogenesis; Dimethylhydrazines; Intestinal Neoplasms; Intestine, Small; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred WF; Time Factors | 1981 |
Differential susceptibility of 3 sublines of C57BL/6 mice to the induction of colorectal tumors by 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Disease Susceptibility; Injections, Subcutaneous; Methylhydrazines; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Rectal Neoplasms | 1980 |
Colonic tumorigenesis in rats with 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Squamous Cell; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Duodenal Neoplasms; Ear Neoplasms; Injections, Subcutaneous; Male; Methylhydrazines; Neoplasms, Experimental; Rats | 1980 |
A study of the effect of colotomy and mucosal field changes in experimental colon cancer.
Topics: Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Intestinal Mucosa; Male; Methods; Neoplasms, Experimental; Rats | 1980 |
Confirmation of the two-step nature of chemical carcinogenesis in the rat colon adenocarcinoma model.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Male; Models, Biological; Neoplasms, Experimental; Rats; Time Factors | 1981 |
Assessment of the nucleolar organizer regions by automated image analysis in benign and malignant colonic tumours and adjacent tissues in rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Colonic Polyps; Dimethylhydrazines; Image Processing, Computer-Assisted; Nucleolus Organizer Region; Rats; Rats, Sprague-Dawley; Silver Staining | 1995 |
Difference in histology and size in colonic tumors of rats receiving two different carcinogens.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Glutamic Acid; Male; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1994 |
Induction of colon adenocarcinomas in rats fed trypsin and tamoxifen diets by parenteral and intragastric 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Diet; Dimethylhydrazines; Gastric Lavage; Infusions, Parenteral; Male; Rats; Rats, Sprague-Dawley; Survival Rate; Tamoxifen; Trypsin | 1994 |
Effect of iron deficiency on DMH-induced gastrointestinal tract tumors and occurrence of hepatocyte abnormalities in Fischer rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Duodenal Neoplasms; Incidence; Iron Deficiencies; Liver; Male; Rats; Rats, Inbred F344 | 1994 |
Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Cholesterol; Colonic Neoplasms; Dimethylhydrazines; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Mice, Inbred ICR; Pravastatin; Simvastatin | 1994 |
Colonic crypts located over lymphoid nodules of 1,2-dimethylhydrazine-treated rats are hyperplastic and at high risk of forming adenocarcinomas.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Cell Cycle; Cell Division; Cocarcinogenesis; Colon; Colonic Neoplasms; Dimethylhydrazines; Epithelium; Hyperplasia; Immunohistochemistry; Lymphoid Tissue; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor alpha | 1994 |
Flat adenoma-adenocarcinoma sequence in the colon of rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Male; Rats; Rats, Sprague-Dawley | 1994 |
Experimental carcinogenesis in the rat intestine induced by two different carcinogens--evaluation of carcinogenic action and its effect on ornithine decarboxylase activity.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Dimethylhydrazines; Intestinal Mucosa; Intestinal Neoplasms; Male; Methylnitrosourea; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley | 1994 |
The effect of misoprostol on colon cancer.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Colonic Neoplasms; Dimethylhydrazines; Female; Humans; Mice; Mice, Nude; Misoprostol; Neoplasm Invasiveness; Random Allocation; Rats; Rats, Sprague-Dawley; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Administration, Oral; Animals; Carcinogens; Cell Division; Choristoma; Colonic Neoplasms; Dimethylhydrazines; Female; Mice; Sphingomyelins; Weight Gain | 1994 |
Failure of tripeptide colon mitosis inhibitor to suppress the cell proliferation of dimethylhydrazine-induced colonic cancers in rats.
Topics: Adenocarcinoma; Adenoma; Amino Acid Sequence; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Growth Inhibitors; Hyperplasia; Intestinal Mucosa; Male; Molecular Sequence Data; Oligopeptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar | 1993 |
Action of estrogen and adrenocorticoids on adenocarcinoma induction by 1,2-dimethylhydrazine in male rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colon; Colonic Neoplasms; Cortisone; Desoxycorticosterone; Dimethylhydrazines; Estradiol; Injections, Subcutaneous; Intestinal Neoplasms; Male; Peanut Oil; Plant Oils; Rats; Rats, Sprague-Dawley | 1993 |
[Establishment of a transplantable rat colon cancer and a model of metastasis].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Liver Neoplasms; Lung Neoplasms; Neoplasm Transplantation; Peritoneal Neoplasms; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1993 |
Pilot study on alcohol-induced chemonecrosis of hepatic metastases from colonic cancer. A new approach for percutaneous localized dynamic destruction of the hepatic spread.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adult; Aged; Animals; Carcinogens; Colectomy; Colon; Colonic Neoplasms; Combined Modality Therapy; Dimethylhydrazines; Dose-Response Relationship, Drug; Ethanol; Female; Humans; Injections, Intralesional; Liver; Liver Neoplasms; Male; Middle Aged; Pilot Projects; Rats; Rats, Sprague-Dawley | 1993 |
Preventive effect of magnesium hydroxide on carcinogen-induced large bowel carcinogenesis in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Colon; Colonic Neoplasms; Dimethylhydrazines; Magnesium Hydroxide; Male; Methylazoxymethanol Acetate; Mitotic Index; Rats; Rats, Inbred F344 | 1993 |
Tumors produced in rats with a single dosage of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Injections, Subcutaneous; Kidney Neoplasms; Male; Pilot Projects; Rats; Rats, Sprague-Dawley; Wilms Tumor | 1993 |
Sulphated bile acid per se inhibits colonic carcinogenesis in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Administration, Oral; Administration, Rectal; Animals; Bile Acids and Salts; Carcinogens; Carcinoma, Squamous Cell; Cholic Acids; Colon; Colonic Neoplasms; Deoxycholic Acid; Dimethylhydrazines; Feces; Female; Germ-Free Life; Injections, Subcutaneous; Lithocholic Acid; Methylnitrosourea; Mice; Mice, Inbred ICR | 1993 |
Photo detection of carcinoma of the colon in a rat model: a pilot study.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma in Situ; Colonic Neoplasms; Dihematoporphyrin Ether; Dimethylhydrazines; Fluorescence; Photography; Pilot Projects; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Effects of menadione on 1,2-dimethylhydrazine-induced mouse colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylhydrazines; DNA, Neoplasm; Female; Intestinal Mucosa; Mice; Mice, Inbred ICR; Superoxide Dismutase; Vitamin K; Vitamin K 3 | 1993 |
Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Carrier Proteins; Colon; Colonic Neoplasms; Dimethylhydrazines; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Humans; Intestinal Neoplasms; Intestine, Small; Male; Neoplasm Proteins; Nerve Tissue Proteins; Phenotype; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Neoplasm; Tumor Suppressor Proteins | 1993 |
Distribution of lymphoid nodules, aberrant crypt foci and tumours in the colon of carcinogen-treated rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Lymphoid Tissue; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1996 |
Promotion of colon carcinogenesis through increasing lipid peroxidation induced in rats by a high cholesterol diet.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Cholesterol; Cholesterol, Dietary; Cholic Acid; Cholic Acids; Cocarcinogenesis; Colon; Colonic Neoplasms; Depression, Chemical; Dimethylhydrazines; Glutathione Peroxidase; Hypercholesterolemia; Lipid Peroxidation; Lipids; Male; Peroxides; Rats; Rats, Sprague-Dawley | 1996 |
Treatment of microscopic pulmonary metastases with recombinant autologous tumor vaccine expressing interleukin 6 and Escherichia coli cytosine deaminase suicide genes.
Topics: Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Cyclophosphamide; Cytosine Deaminase; Dimethylhydrazines; Disease Progression; Female; Fibrosarcoma; Gene Transfer Techniques; Genetic Vectors; Immunocompromised Host; Immunosuppressive Agents; Interleukin-6; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred C57BL; Nucleoside Deaminases; Tumor Cells, Cultured; Vaccines, Synthetic | 1996 |
[Inhibition of colorectal carcinoma induced by 1, 2-dimethylhydrazine in mice with tea polyphenols].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Flavonoids; Free Radical Scavengers; Male; Mice; Mice, Inbred ICR; Phenols; Polymers; Polyphenols; Tea | 1995 |
Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: implications for dietary sphingolipids and colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Female; Mice; Precancerous Conditions; Sphingomyelins | 1996 |
[Effect of melatonin on 1,2-dimethylhydrazine-induced intestinal tumors in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Intestinal Neoplasms; Melatonin; Rats; Rats, Inbred Strains | 1996 |
Cyclosporin A enhances locoregional metastasis of the CC531 rat colon tumour.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Carcinogens; Colonic Neoplasms; Cyclosporine; Dimethylhydrazines; Doxorubicin; Drug Resistance, Neoplasm; Immunosuppressive Agents; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Specific Pathogen-Free Organisms | 1997 |
Zinc deprivation promotes progression of 1,2-dimethylhydrazine-induced colon tumors but reduces malignant invasion in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Carcinoma in Situ; Collagenases; Colon; Colonic Neoplasms; Diet; Dimethylhydrazines; Immunohistochemistry; Liver; Male; Matrix Metalloproteinase 9; Mice; Neoplasm Invasiveness; Organ Size; Zinc | 1997 |
Interaction of dietary fat with a vegetables-fruit mixture on 1,2-dimethylhydrazine-induced colorectal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Body Weight; Carcinogens; Colorectal Neoplasms; Dietary Fats; Dimethylhydrazines; Energy Intake; Fruit; Male; Rats; Rats, Wistar; Vegetables | 1997 |
Interaction of dietary fat and of a vegetables/fruit mixture on 1,2-dimethylhydrazine- or N-methyl-N'-nitro-N-nitrosoguanidine-induced colorectal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colorectal Neoplasms; Dietary Fats; Dimethylhydrazines; Fruit; Intestinal Neoplasms; Male; Methylnitronitrosoguanidine; Rats; Rats, Wistar; Vegetables | 1997 |
Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Diet; Dimethylhydrazines; Female; Mice; Milk; Precancerous Conditions; Sphingolipids; Sphingomyelins; Weight Gain | 1997 |
Preventive effect of 1-(2-tetrahydrofuryl)-5-fluorouracil in combination with uracil on colonic carcinogenesis induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Colorectal Neoplasms; Dimethylhydrazines; Fluorouracil; Male; Rats; Tegafur; Thymidine Kinase; Thymidylate Synthase; Uracil | 1997 |
Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Female; Intestinal Neoplasms; Melatonin; Rats | 1997 |
Development of oxygen insensitivity of the quantitative histochemical assay of G6PDH activity during colorectal carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Colon; Colonic Neoplasms; Colonic Polyps; Crohn Disease; Dimethylhydrazines; Female; Glucosephosphate Dehydrogenase; Histocytochemistry; Hyperplasia; Intestinal Mucosa; Mice; Mice, Mutant Strains; Oxygen; Precancerous Conditions; Predictive Value of Tests | 1997 |
The incidence of aberrant crypt foci and colonic carcinoma in dimethylhydrazine-treated rats varies in a site-specific manner and depends on tumor histology.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma; Cecal Neoplasms; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Rats; Rats, Wistar | 1997 |
Electrochemotherapy against colorectal carcinoma: comparison of in vitro cytotoxicity of 5-fluorouracil, cisplatin and bleomycin.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bleomycin; Cell Membrane Permeability; Cisplatin; Colorectal Neoplasms; Culture Media, Serum-Free; Dimethylhydrazines; Drug Screening Assays, Antitumor; Electroporation; Fluorouracil; Humans; Intracellular Fluid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Tumor Cells, Cultured | 1999 |
Cellulose and calcium lower the incidence of chemically-induced colon tumors in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Calcium, Dietary; Carcinogens; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Disease Models, Animal; Folic Acid; Male; Random Allocation; Rats; Rats, Inbred F344 | 1999 |
Rat colorectal tumours treated with a range of non-steroidal anti-inflammatory drugs show altered cyclooxygenase-2 and cyclooxygenase-1 splice variant mRNA expression levels.
Topics: Adenocarcinoma; Adenoma; Alternative Splicing; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Dimethylhydrazines; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Isoenzymes; Membrane Proteins; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger | 2001 |
Aberrant crypt foci and colon cancer: comparison between a short- and medium-term bioassay for colon carcinogenesis using dimethylhydrazine in Wistar rats.
Topics: Adenocarcinoma; Animals; Biological Assay; Biomarkers, Tumor; Carcinogenicity Tests; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Male; Precancerous Conditions; Rats; Rats, Wistar | 2002 |
Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Cycle Proteins; Chromosomal Proteins, Non-Histone; Chromosome Mapping; Colonic Neoplasms; Dimethylhydrazines; Gene Deletion; Gene Silencing; Genetic Markers; Humans; Loss of Heterozygosity; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Nuclear Proteins; Phosphoproteins; Polymorphism, Genetic; Protein Tyrosine Phosphatases; Quantitative Trait, Heritable; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 2002 |
Nitrogen intake and tumorigenesis in rats injected with 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Ammonia; Animals; Blood Urea Nitrogen; Caseins; Cecum; Cholesterol; Colon; Colonic Neoplasms; Dietary Proteins; Dimethylhydrazines; Ear Neoplasms; Female; Hydrazines; Hydrogen-Ion Concentration; Intestinal Neoplasms; Intestine, Small; Neoplasms; Nitrogen; Papilloma; Rats; Urea; Urease | 1976 |
Gamma glutamyl transpeptidase in colon cancer induced by 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Age Factors; Animals; Animals, Newborn; Colon; Colonic Neoplasms; Dimethylhydrazines; gamma-Glutamyltransferase; Histocytochemistry; Hydrazines; Intestine, Small; Male; Rats | 1977 |
Evaluation of the cytotoxicity of dihydroxytryptamines and 5-hydroxytryptamine antagonists as cytotoxic agents in dimethylhydrazine-induced adenocarcinomata.
Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Adenocarcinoma; Animals; Antineoplastic Agents; Cyproheptadine; Dihydroxytryptamines; Dimethylhydrazines; Lysergic Acid Diethylamide; Male; Methysergide; Mitosis; Neoplasms, Experimental; Rats; Serotonin Antagonists | 1978 |
Cell population kinetics of 1,2-dimethylhydrazine-induced colonic neoplasms and their adjacent colonic mucosa in the mouse.
Topics: Adenocarcinoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Female; Intestinal Mucosa; Kinetics; Mice | 1979 |
Failure of bran to protect against experimental colon cancer in rats.
Topics: Adenocarcinoma; Animals; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Evaluation Studies as Topic; Female; Neoplasms, Experimental; Rats | 1978 |
Cell proliferation in dimethylhydrazine-induced colonic adenocarcinomata following cytotoxic drug treatment.
Topics: 5,7-Dihydroxytryptamine; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Cimetidine; Colonic Neoplasms; Dimethylhydrazines; Fluorouracil; Male; Rats; Time Factors | 1978 |
Pathological features of the colonic tumours induced in rats by the administration of 1,2-dimethylhydrazine.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Cell Differentiation; Colonic Neoplasms; Dimethylhydrazines; Female; Rats | 1978 |
Production of intestinal and other tumours by 1,2-dimethylhydrazine dihydrochloride in mice. II. Scanning electron microscopic and cytochemical study of colonic neoplasms.
Topics: Adenocarcinoma; Adenosine Triphosphatases; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Female; Glycosaminoglycans; Histocytochemistry; Mice; Microscopy, Electron, Scanning | 1976 |
Chemotherapy studies in autochthonous rat tumors intestinal cancer.
Topics: Adenocarcinoma; Animals; Cyclophosphamide; Dimethylhydrazines; Dimethylnitrosamine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Male; Methotrexate; Methylnitronitrosoguanidine; Rats | 1978 |
Immunologic aspects of 1, 2-dimethylhydrazine-induced colon tumors in rats.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Antibody Formation; Antigens, Neoplasm; Carcinoembryonic Antigen; Colon; Colonic Neoplasms; Cross Reactions; Dimethylhydrazines; Fetus; Intubation, Gastrointestinal; Male; Neoplasms, Experimental; Rats | 1975 |
Histogenesis and growth pattern of 1,2-dimethylhydrazine-induced rat colon adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; DNA, Neoplasm; Epithelium; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1976 |
Cyclic nucleotide concentrations in 1,2-dimethylhydrazine induced rat colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; Dimethylhydrazines; Female; Rats | 1978 |
[Studies on carcinogenesis and extension of 1,2-dimethylhydrazine induced large-bowel cancer in rats (author's transl)].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Methylhydrazines; Neoplasms, Experimental; Rats | 1978 |
Cyclic nucleotide concentrations in 1,2-dimethylhydrazine and x-ray induced rat small intestinal cancer.
Topics: Adenocarcinoma; Animals; Cyclic AMP; Cyclic GMP; Dimethylhydrazines; Intestinal Neoplasms; Intestine, Small; Male; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Rats | 1978 |
Lysosomal enzymes in macrophages of colonic tumors induced in rats by 1,2-dimethylhydrazine dihydrochloride.
Topics: Acid Phosphatase; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Glucuronidase; Lysosomes; Macrophages; Male; Methylhydrazines; Neoplasms, Experimental; Rats | 1978 |
Strain differences in susceptibility of rat colon to 1,2-dimethylhydrazine carcinogenesis.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Colonic Neoplasms; Dimethylhydrazines; Female; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Species Specificity | 1978 |
Adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate phosphodiesterase activities in 1,2-dimethylhydrazine induced colon adenocarcinoma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenocarcinoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Methylhydrazines; Neoplasms, Experimental; Rats | 1979 |
Effect of embryonic tissue immunization on chemically induced gastrointestinal tumors in rats. I. Can embryonic antigens act as rejection antigens?
Topics: Adenocarcinoma; Animals; Antibodies, Neoplasm; Antigens; Dimethylhydrazines; Fetus; Gastrointestinal Neoplasms; Immunity; Methylhydrazines; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Rats, Inbred WF; Skin; Time Factors | 1978 |
Induction of colon tumors in 1,2-dimethylhydrazine-resistant Lobund Wistar rats by methylazoxymethanol acetate.
Topics: Adenocarcinoma; Animals; Azo Compounds; Biotransformation; Colon; Colonic Neoplasms; Dimethylhydrazines; Drug Resistance; Female; Intestinal Neoplasms; Male; Methylazoxymethanol Acetate; Methylhydrazines; Neoplasms, Experimental; Rats; Species Specificity | 1978 |
Ultrastructure of 1,2-dimethylhydrazine-induced adenocarcinomas in rat colon.
Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Differentiation; Cell Membrane; Cell Nucleus; Colonic Neoplasms; Dimethylhydrazines; Epithelium; Male; Methylhydrazines; Microscopy, Electron; Necrosis; Neoplasms, Experimental; Rats; Thymidine | 1978 |
Protective effect of oral Salmonella enteritidis 11RX infection against colon tumor induction by 1,2-dimethylhydrazine in mice.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Salmonella enteritidis; Salmonella Infections | 1979 |
Lack of effect of butylated hydroxytoluene on dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: Adenocarcinoma; Animals; Butylated Hydroxytoluene; Colonic Neoplasms; Cresols; Dimethylhydrazines; Duodenal Neoplasms; Male; Methylhydrazines; Neoplasms, Experimental; Rats | 1979 |
[Effect of BCG immunotherapy on kinetic parameters and growth curves of 5 transplantable lines of colon carcinoma chemically induced in rat (author's transl)].
Topics: Adenocarcinoma; Animals; BCG Vaccine; Cell Line; Colonic Neoplasms; Dimethylhydrazines; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1979 |
Selective protective effect of butylated hydroxytoluene against 1,2-dimethylhydrazine carcinogenesis in BALB/c mice.
Topics: Adenocarcinoma; Adenoma; Animals; Butylated Hydroxytoluene; Colonic Neoplasms; Dimethylhydrazines; Female; Male; Methylhydrazines; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Sex Factors | 1979 |
Occult blood testing using the guaiac method (haemoccult-test) for detection of tumorous lesions induced with 1,2-dimethyl-hydrazine and acetoxymethyl-methyl-nitrosamine in rats.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Guaiac; Male; Occult Blood; Rats | 1979 |
Effect of mitomycin-C on McCall rat colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Female; Injections, Intraperitoneal; Male; Mitomycins; Neoplasms, Experimental; Rats; Time Factors | 1978 |
Induction of tumors in mice with the herbicide succinic acid 2,2-dimethylhydrazide.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Dimethylhydrazines; Female; Hemangioma; Hemangiosarcoma; Hydrazines; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Methylhydrazines; Mice; Neoplasms, Experimental; Succinates | 1977 |
Cellular binding proteins for vitamin A in colorectal adenocarcinoma of rat.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Intestinal Mucosa; Male; Neoplasm Proteins; Neoplasms, Experimental; Rats; Rectal Neoplasms; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular | 1978 |
Histogenesis of symmetrical 1,2-dimethylhydrazine-induced neoplasms of the colon in the mouse.
Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Female; Hyperplasia; Intestinal Mucosa; Methylhydrazines; Mice; Neoplasms, Experimental; Precancerous Conditions; Time Factors | 1978 |
Inhibition of 1,2-dimethylhydrazine-induced neoplasia of the large intestine in female CF1 mice by carbon disulfide.
Topics: Adenocarcinoma; Adenoma; Animals; Carbon Disulfide; Carcinoma, Squamous Cell; Dimethylhydrazines; Female; Intestinal Neoplasms; Methylhydrazines; Mice; Neoplasms, Experimental | 1978 |
Strain susceptibility and resistance to 1,2-dimethylhydrazine-induced enteric tumors in germfree rats.
Topics: Adenocarcinoma; Animals; Dimethylhydrazines; Female; Germ-Free Life; Intestinal Neoplasms; Intestines; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Species Specificity | 1978 |
Stimulation of cell proliferation by histamine H2 receptors in dimethylhdrazine-induced adenocarcinomata.
Topics: Adenocarcinoma; Animals; Cell Division; Cimetidine; Colon; Colonic Neoplasms; Dimethylhydrazines; Histamine; Intestinal Mucosa; Male; Metiamide; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Thiourea | 1978 |
A double-blind study on the effect of purified cellulose dietary fiber on 1,2-dimethylhydrazine-induced rat colonic neoplasia.
Topics: Adenocarcinoma; Animals; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Double-Blind Method; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Time Factors | 1978 |
Experimental colonic tumours in the rat. II. Double contrast examination and microscopy.
Topics: Adenocarcinoma; Adenoma; Animals; Colon; Colonic Neoplasms; Contrast Media; Dimethylhydrazines; Female; Intestinal Mucosa; Intestinal Polyps; Male; Methylnitronitrosoguanidine; Neoplasms, Experimental; Radiography; Rats | 1978 |
Experimental colonic tumours in the rat. III. Induction time, distribution and appearance of induced tumours.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Female; Hyperplasia; Injections; Injections, Intravenous; Injections, Subcutaneous; Intestinal Mucosa; Male; Methylnitronitrosoguanidine; Neoplasm Metastasis; Neoplasms, Experimental; Radiography; Rats; Rectum; Time Factors | 1978 |
[Neomycin sulfate and colonic carcinoma. Experimental study].
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Male; Neomycin; Rats | 1978 |
Induction of colonic adenocarcinomas by 1,2-dimethylhydrazine intrarectally administered in rats.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Hyperplasia; Injections; Intestinal Mucosa; Methylhydrazines; Neoplasms, Experimental; Rats; Rectum | 1978 |
[Ultrastructure study of the preneoplastic colon (carcinogenesis with 1,2-dimethylhydrazine)].
Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dimethylhydrazines; Microscopy, Electron; Neoplasms, Experimental; Precancerous Conditions; Rats; Time Factors | 1978 |
Cell proliferation in the descending colon of dimethylhydrazine treated rats and in dimethylhydrazine induced adenocarcinomata.
Topics: Adenocarcinoma; Animals; Cell Division; Colon; Colonic Neoplasms; Dimethylhydrazines; Hydrazines; Male; Mitosis; Rats; Time Factors; Vinblastine | 1976 |
A comparison of cell proliferation in normal and neoplastic intestinal epithelia following either biogenic amine depletion or monoamine oxidase inhibition.
Topics: Adenocarcinoma; Animals; Biogenic Amines; Cell Division; Colon; Colonic Neoplasms; Dimethylhydrazines; Intestinal Mucosa; Jejunum; Male; Monoamine Oxidase Inhibitors; Nialamide; Rats; Reserpine | 1976 |
Dimethylhydrazine-induced colon tumors in rats fed diets containing beef fat or corn oil with and without wheat bran.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Diet; Dietary Fats; Dietary Fiber; Dimethylhydrazines; Dose-Response Relationship, Drug; Hydrazines; Male; Oils; Rats; Triticum | 1977 |
Inhibitory effects of selenium on 1,2-dimethylhydrazine and methylazoxymethanol acetate induction of colon tumors.
Topics: Adenocarcinoma; Animals; Azo Compounds; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Hydrazines; Male; Methylazoxymethanol Acetate; Neoplasms, Experimental; Rats; Selenium | 1977 |
Cytotoxicity of 5,6-dihydroxytryptamine in dimethylhydrazine-induced carcinomas of rat colon.
Topics: 5,6-Dihydroxytryptamine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Hydrazines; Male; Neoplasms, Experimental; Rats; Tryptamines | 1977 |
[Cholecystectomy and experimental coloncarcinoma (author's transl)].
Topics: Adenocarcinoma; Animals; Cholecystectomy; Colonic Neoplasms; Dimethylhydrazines; Female; Mice | 1977 |
[Malignant degeneration of experimental ulcerative colitis of the rat following s.c. injection of 1,2-dimethylhydrazine (author's transl)].
Topics: Adenocarcinoma; Animals; Colitis, Ulcerative; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Male; Rats | 1977 |
Morphological studies of chemically induced colon tumors in hamsters.
Topics: Adenocarcinoma; Animals; Colon; Colonic Neoplasms; Cricetinae; Dimethylhydrazines; Kidney Cortex; Liver; Liver Neoplasms; Male; Neoplasm Metastasis | 1977 |
[Kinetics of populations of enterocytes of experimental tumors of the large intestine in rats].
Topics: Adenocarcinoma; Animals; Autoradiography; Cell Division; Dimethylhydrazines; DNA, Neoplasm; Epithelium; Intestinal Neoplasms; Intestine, Large; Male; Mitosis; Neoplasms, Experimental; Protein Glutamine gamma Glutamyltransferase 2; Rats; Thymidine | 1977 |
Effect of high-fat diet on colon carcinogenesis in F344 rats treated with 1,2-dimethylhydrazine, methylazoxymethanol acetate, or methylnitrosourea.
Topics: Adenocarcinoma; Adenoma; Animals; Azo Compounds; Cattle; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Male; Meat; Methylazoxymethanol Acetate; Methylhydrazines; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344 | 1977 |
The large bowel carcinogenic effects of hydrazines and related compounds occurring in nature and in the environment.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens, Environmental; Colonic Neoplasms; Cricetinae; Dimethylhydrazines; Female; Hydrazines; Liver Neoplasms; Male; Methylhydrazines; Mice; Rats; Splenic Neoplasms | 1977 |
Influence of gonadal hormones and age on 1,2-dimethylhydrazine-induced colon carcinogenesis.
Topics: Adenocarcinoma; Aging; Animals; Castration; Colonic Neoplasms; Dihydrotestosterone; Dimethylhydrazines; Female; Gonadal Steroid Hormones; Male; Methylhydrazines; Rats; Sex Factors | 1977 |
Changes in chromosomal proteins in colon cancer: the complexity and DNA-binding properties of tumor-associated proteins and evidence for their association with the malignant state in human colonic epithelium.
Topics: Adenocarcinoma; Animals; Chromatography, Affinity; Chromosomal Proteins, Non-Histone; Colonic Neoplasms; Dimethylhydrazines; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Male; Neoplasm Proteins; Rats | 1977 |
Production of intestinal and other tumors by 1, 2-dimethylhydrazine dihydrochloride in mice. I. A light and transmission electron microscopic study of colonic neoplasms.
Topics: Adenocarcinoma; Adenoma; Animals; Anus Neoplasms; Carcinoma, Squamous Cell; Colon; Dimethylhydrazines; Female; Hemangioma; Hemangiosarcoma; Hydrazines; Intestinal Neoplasms; Intestine, Large; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mice; Microscopy, Electron; Neoplasms, Experimental | 1976 |
Experimental carcinoma of the colon induced by 1,2-dimethylhydrazine-diHCl: value as a model of human disease.
Topics: Adenocarcinoma; Animals; Carcinoma; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Female; Humans; Intestinal Polyps; Lymphatic Metastasis; Male; Neoplasm Metastasis; Neoplasm Transplantation; Rats | 1976 |
Sequential studies of serum blocking activity in rats bearing chemically induced primary bowel tumors.
Topics: Adenocarcinoma; Aminobiphenyl Compounds; Animals; Antigen-Antibody Complex; Carcinogens; Colonic Neoplasms; Cytotoxicity Tests, Immunologic; Dimethylhydrazines; Intestinal Neoplasms; Lymph Nodes; Lymphocytes; Neoplasms, Experimental; Nitrosoguanidines; Radiography; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1975 |
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosomethylurethane; Transplantation, Homologous | 1975 |
Tumor-associated and embryonic antigens in soluble fractions of a chemically-induced rat colon carcinoma.
Topics: Adenocarcinoma; Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Carcinoembryonic Antigen; Cells, Cultured; Colonic Neoplasms; Cytotoxicity Tests, Immunologic; Dimethylhydrazines; Lymph Nodes; Lymphocytes; Methylnitronitrosoguanidine; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred BUF; Rats, Inbred WF; Transplantation, Homologous | 1975 |
Effects of cholestyramine on 1,2-dimethylhydrazine-induced enteric carcinoma in germfree rats.
Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Carcinogens; Cecum; Cholestyramine Resin; Dimethylhydrazines; Drug Synergism; Female; Germ-Free Life; Hydrazines; Intestinal Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1975 |
[Change in cell membrane permeability, and composition and properties of hexokinase during induced carcinogenesis].
Topics: Adenocarcinoma; Animals; Cell Membrane Permeability; Dimethylhydrazines; Hexokinase; Hydrazines; Intestinal Neoplasms; Intestine, Large; Isoenzymes; Neoplasm Metastasis; Neoplasms, Experimental; Rats | 1975 |
[An enzymohistochemical study of experimental tumors of the intestine].
Topics: Adenocarcinoma; Animals; Dimethylhydrazines; Histocytochemistry; Intestinal Mucosa; Intestinal Neoplasms; Male; Neoplasms, Experimental; Rats | 1975 |
[Proliferative activity of the epithelium of the rat large intestine during carcinogenesis].
Topics: Adenocarcinoma; Animals; Carcinoma in Situ; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Mitosis; Rats | 1976 |
Effect of quality and quantity of dietary fat and dimethylhydrazine in colon carcinogenesis in rats.
Topics: Adenocarcinoma; Animals; Carcinoma; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Ear Canal; Ear Neoplasms; Female; Hydrazines; Intestinal Neoplasms; Kidney Neoplasms; Neoplasms, Experimental; Rats | 1976 |
Dietary supplementation with pectin and guar gum on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Energy Intake; Galactans; Male; Mannans; Pectins; Plant Gums; Rats; Rats, Inbred Strains | 1992 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Incidence; Inflammatory Bowel Diseases; Male; Mesalamine; Metronidazole; Neoplasm Invasiveness; Rats; Rats, Wistar; Sulfasalazine | 1992 |
Histological reactivity of a monoclonal antibody against rat colon cancer cells on human and rat normal gut and colonic tumours.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antibodies, Monoclonal; Blood Group Antigens; Carbohydrate Conformation; Carbohydrate Sequence; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Epitopes; Female; Fluorescein-5-isothiocyanate; Gastric Mucosa; Humans; Immunoenzyme Techniques; Intestinal Mucosa; Male; Molecular Sequence Data; Oligosaccharides; Organ Specificity; Rats; Rats, Inbred Strains | 1992 |
Carcinogenicity of 1,2-dimethylhydrazine in colorectal tissue heterotopically transplanted into the glandular stomach of rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colon; Colorectal Neoplasms; Dimethylhydrazines; Injections, Intramuscular; Intestinal Mucosa; Male; Mucins; Rats; Rats, Inbred F344; Sialomucins; Stomach | 1992 |
Alterations in protein kinase C in 1,2-dimethylhydrazine induced colonic carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Intestinal Mucosa; Isoenzymes; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains | 1992 |
Action of hydrazine drugs in tumor-free and 1,2-dimethylhydrazine-treated male rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Hydralazine; Injections, Subcutaneous; Isoniazid; Male; Phenelzine; Rats; Rats, Inbred Strains | 1992 |
Tumor induction in monkeys after administration of dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Female; Macaca fascicularis; Male; Myoma; Neoplasms, Experimental; Uterine Neoplasms | 1992 |
Rat monoclonal antibodies produced against rat colorectal adenocarcinomas define tumor- and colon-associated, auto-immunogenic antigens.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Autoantigens; Carcinogens; Cell Line; Colorectal Neoplasms; Dimethylhydrazines; Epitopes; Female; Immunoblotting; Interferon-gamma; Male; Radioimmunoassay; Rats; Rats, Inbred BN; Rats, Inbred WF | 1990 |
[Effects of fecal bile acids on experimental colon carcinogenesis].
Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Colonic Neoplasms; Dimethylhydrazines; Feces; Gastrointestinal Transit; Ileum; Jejunum; Male; Rats; Rats, Inbred Strains | 1991 |
[Effect of gastrin and enprostil, a PGE2 analog, on colonic cancerous cell growth].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Drug Combinations; Enprostil; Gastrins; Proglumide; Rats; Stimulation, Chemical; Tumor Cells, Cultured | 1991 |
[Mucosubstance and lectin histochemistry of DMH induced colonic tumor in rats].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Histocytochemistry; Intestinal Mucosa; Lectins; Male; Mucus; Rats; Rats, Inbred Strains | 1991 |
Sulindac inhibits the rate of growth and appearance of colon tumors in the rat.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Colonic Neoplasms; Dimethylhydrazines; Male; Random Allocation; Rats; Rats, Inbred Strains; Remission Induction; Sulindac | 1991 |
The thalidomide analog, EM 12, enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; Body Weight; Carcinogens; Colon; Dimethylhydrazines; Drug Synergism; Intestinal Neoplasms; Intestine, Small; Male; Rats; Rats, Inbred Strains; Thalidomide | 1991 |
Demonstration of the need for end point validation of putative biomarkers: failure of aberrant crypt foci to predict colon cancer incidence.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Colon; Colonic Neoplasms; Corn Oil; Diet; Dimethylhydrazines; Male; Pectins; Prognosis; Rats; Rats, Inbred Strains; Regression Analysis | 1991 |
Quantification of acid mucins in the descending colon of rats having simultaneously growing colonic tumors.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alcian Blue; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Female; Intestinal Mucosa; Mucins; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Development of lung metastases after curative intraperitoneal chemotherapy in a rat colon cancer model.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dimethylhydrazines; Injections, Intraperitoneal; Lung Neoplasms; Rats; Rats, Inbred F344 | 1991 |
Alterations in lectin binding in the proximal and distal colon of Sprague-Dawley rats with 1,2 dimethylhydrazine administration.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Lectins; Male; Microscopy, Fluorescence; Mucins; Plant Lectins; Rats; Rats, Inbred Strains | 1991 |
Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethyl-hydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; alpha-Linolenic Acid; Animals; Body Weight; Carcinogens; Carcinoma, Papillary; Carcinoma, Squamous Cell; Colonic Neoplasms; Dietary Fats, Unsaturated; Dimethylhydrazines; Ear Neoplasms; Female; Linoleic Acids; Mammary Neoplasms, Animal; Methylhydrazines; Papilloma; Plant Oils; Rats; Rats, Inbred Strains; Safflower Oil; Sebaceous Gland Neoplasms; Soybean Oil | 1990 |
[Effects of hyperthermochemotherapy on activities of DNA-synthesizing enzymes in 1, 2-dimethylhydrazine (DMH)-induced colon carcinomas in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Dimethylhydrazines; Hyperthermia, Induced; Isoenzymes; Rats; Rats, Inbred Strains; Tegafur; Thymidine Kinase; Thymidylate Synthase; Uracil | 1990 |
Effect of germanium on 1,2-dimethylhydrazine-induced intestinal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Carcinogens; Dimethylhydrazines; Germanium; Intestinal Neoplasms; Male; Rats; Rats, Inbred Strains | 1990 |
[Growth rate of experimental colonic cancer in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Barium Sulfate; Colonic Neoplasms; Dimethylhydrazines; Enema; Male; Radiography; Rats; Rats, Inbred Strains | 1990 |
[Modifying effects of changes connected with pregnancy on 1,2-dimethylhydrazine-induced carcinogenesis in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Colonic Neoplasms; Dimethylhydrazines; Female; Kidney Neoplasms; Lactation; Liver Neoplasms; Mesenchymoma; Neoplasms, Experimental; Parity; Pregnancy; Pseudopregnancy; Rats | 1990 |
Lipid absorption and intestinal tumour incidence in rats fed on varying levels of calcium and butterfat.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Butter; Calcium, Dietary; Carcinogens; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Feces; Intestinal Absorption; Lipid Metabolism; Lipids; Male; Rats; Rats, Inbred Strains | 1990 |
Effect of polyamine oxidase inhibition on the colonic malignant transformation process induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenocarcinoma; Animals; Base Sequence; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Genes, ras; Male; Molecular Sequence Data; Neoplasms, Experimental; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polymerase Chain Reaction; Putrescine; Rats; Rats, Inbred Strains | 1990 |
An assessment of the risk of neoplasia in long-term ileal reservoirs using the DMH rodent model.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Ileal Neoplasms; Ileostomy; Ileum; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Suppression of dimethylhydrazine-induced carcinogenesis in mice by dietary addition of the Bowman-Birk protease inhibitor.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma, Squamous Cell; Dimethylhydrazines; Gastrointestinal Neoplasms; Liver Neoplasms; Liver Neoplasms, Experimental; Methylhydrazines; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organ Size; Pancreas; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors | 1990 |
Microvascular architecture of experimental colon tumors in the rat.
Topics: Adenocarcinoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Microcirculation; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Reference Values | 1990 |
Dietary milk proteins inhibit the development of dimethylhydrazine-induced malignancy.
Topics: Adenocarcinoma; Animals; Body Weight; Caseins; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Female; Methylhydrazines; Mice; Milk Proteins | 1990 |
[The induction of cancer of the large intestine in Macaca fascicularis monkeys with 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Dimethylhydrazines; Dose-Response Relationship, Drug; Female; Injections, Subcutaneous; Intestinal Neoplasms; Intestine, Large; Lymphatic Metastasis; Macaca fascicularis; Male; Methylhydrazines; Time Factors | 1990 |
Colonic cancer induced by 1,2-dimethylhydrazine: promotion by experimental colitis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colitis; Colonic Neoplasms; Dimethylhydrazines; Male; Methylhydrazines; Mice | 1989 |
Effect of indomethacin in autotransplanted colonic tumors.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Indomethacin; Kidney; Kidney Neoplasms; Male; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1989 |
Reduction of DMH-induced colon tumors in rats fed psyllium husk or cellulose.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Feces; Male; Methylhydrazines; Psyllium; Rats; Rats, Inbred Strains | 1987 |
Enzyme histochemical studies on DMH-induced colonic adenocarcinoma in mice.
Topics: Acetylcholinesterase; Adenocarcinoma; Animals; Cathepsin B; Colonic Neoplasms; Dimethylhydrazines; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Glucuronidase; Histocytochemistry; Mice; Mice, Inbred ICR; Oxidoreductases; Phosphoric Monoester Hydrolases | 1987 |
[Colonic cancer induced by 1,2-dimethylhydrazine (DMH) in rats after partial colectomy].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Colectomy; Colonic Neoplasms; Dimethylhydrazines; Male; Rats; Rats, Inbred Strains | 1987 |
Experimental liver metastasis. Implications of clonal proclivity and organ specificity.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cecal Neoplasms; Colonic Neoplasms; Dimethylhydrazines; Liver; Liver Neoplasms, Experimental; Lung; Lung Neoplasms; Male; Neoplasm Transplantation; Organ Specificity; Rats; Rats, Inbred BN; Rats, Inbred WF | 1989 |
Premalignant alterations in rat colonic N1-acetylspermidine levels induced by 1,2-dimethylhydrazine: effects of a high corn oil dietary regimen.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Biogenic Polyamines; Colonic Neoplasms; Corn Oil; Dimethylhydrazines; Intestinal Mucosa; Male; Methylhydrazines; Plant Oils; Precancerous Conditions; Rats; Rats, Inbred Strains; Spermidine | 1989 |
N-acetylneuraminic acid and N-glycolylneuraminic acid in glycopeptides of colonic tumor and mucosa in rats treated with carrageenan and 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carrageenan; Colonic Neoplasms; Dimethylhydrazines; Glycopeptides; Intestinal Mucosa; Methylhydrazines; N-Acetylneuraminic Acid; Neuraminic Acids; Rats; Sialic Acids | 1989 |
Stromal reaction associated with the DMH-induced mice colon carcinogenesis.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Female; Granulocytes; Lymphocytes; Mice; Mice, Inbred ICR | 1987 |
Mast cells in experimental and human cancerogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cervix Uteri; Colon; Colonic Neoplasms; Dimethylhydrazines; Female; Germ-Free Life; Humans; Mast Cells; Mice; Mice, Inbred ICR; Uterine Cervical Neoplasms | 1987 |
Rodent models for carcinoma of the colon.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alkylation; Animals; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Dietary Proteins; Dimethylhydrazines; Disease Models, Animal; Female; Male; Mice; Mice, Inbred Strains; Minerals; Rats; Rats, Inbred F344; Vitamins | 1985 |
Relationship between colonic luminal pH, cell proliferation, and colon carcinogenesis in 1,2-dimethylhydrazine treated rats fed high fiber diets.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cell Division; Cellulose; Colon; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Feces; Galactans; Hydrogen-Ion Concentration; Male; Mannans; Pectins; Plant Gums; Rats; Rats, Inbred Strains | 1986 |
The role of sphingomyelin synthetase and sphingomyelinase in 1,2-dimethylhydrazine-induced lipid alterations of rat colonic plasma membranes.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Membrane Fluidity; Methylhydrazines; Microvilli; Phosphoric Diester Hydrolases; Phosphotransferases; Rats; Sphingomyelin Phosphodiesterase; Sphingomyelins; Transferases (Other Substituted Phosphate Groups) | 1986 |
The interaction of retrovirus and chemical carcinogen in experimental colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Injections, Intraperitoneal; Injections, Subcutaneous; Intestinal Neoplasms; Male; Methylhydrazines; Models, Biological; Oncogenes; Rats; Rats, Inbred Strains; Retroviridae Infections | 1987 |
Activated K-ras in tumorigenic and non-tumorigenic cell variants from a rat colon adenocarcinoma, induced by dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Base Sequence; Colonic Neoplasms; Dimethylhydrazines; DNA, Neoplasm; Killer Cells, Natural; Proto-Oncogenes; Rats; Trypsin; Tumor Cells, Cultured | 1988 |
Characterization of stereomicroscopically identified preneoplastic lesions during dimethylhydrazine-induced colonic carcinogenesis.
Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Dimethylhydrazines; Female; Histocytochemistry; Intestinal Mucosa; Methylhydrazines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1988 |
A protective effect of sulindac against chemically-induced primary colonic tumours in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Indenes; Mice; Mice, Inbred BALB C; Sulindac | 1988 |
Superoxide dismutase activity during dimethylhydrazine colon carcinogenesis and the effects of cholic acid and indole.
Topics: Adenocarcinoma; Animals; Cholic Acid; Cholic Acids; Colonic Neoplasms; Dimethylhydrazines; Indoles; Mice; Superoxide Dismutase; Time Factors | 1988 |
Rat colonic carcinogenesis after ureterosigmoidostomy: pathogenesis and immunohistological study.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Antigens, Neoplasm; Colon, Sigmoid; Colonic Neoplasms; Dimethylhydrazines; Female; Immunoenzyme Techniques; Mucins; Rats; Rats, Inbred Strains; Urinary Diversion | 1988 |
Expression of cell-surface antigens on rat colonic cancer cells.
Topics: Adenocarcinoma; Adenoma; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Colonic Neoplasms; Dimethylhydrazines; Enzyme-Linked Immunosorbent Assay; Immunoassay; Immunohistochemistry; Male; Microvilli; Molecular Weight; Rats; Rats, Inbred F344 | 1988 |
Induction of beta-glucuronidase activity during dimethylhydrazine carcinogenesis and additive effects of cholic acid and indole.
Topics: Adenocarcinoma; Animals; Cholic Acids; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Enzyme Activation; Female; Glucuronidase; Hyperplasia; Indoles; Intestinal Mucosa; Intestine, Large; Methylhydrazines; Mice | 1988 |
Splenectomy and the induction of murine colon cancer.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma in Situ; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Humans; Male; Rats; Rats, Inbred Strains; Splenectomy | 1988 |
Stimulating effect of pentagastrin on cancer cell proliferation kinetics in chemically induced colon cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Dimethylhydrazines; DNA Replication; Kinetics; Male; Pentagastrin; Rats; Rats, Inbred Strains | 1988 |
Cellular proliferation in proximal and distal rat colon during 1,2-dimethylhydrazine-induced carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Autoradiography; Carcinogens; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Male; Methylhydrazines; Rats; Rats, Inbred Strains; Thymidine; Time Factors; Tritium | 1988 |
Interactions of selenium deficiency, vitamin E, polyunsaturated fat, and saturated fat on azoxymethane-induced colon carcinogenesis in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Fatty Acids, Unsaturated; Intestinal Neoplasms; Male; Rats; Rats, Inbred F344; Selenium; Vitamin E | 1986 |
Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol.
Topics: Adenocarcinoma; Analysis of Variance; Animal Feed; Animals; Aryl Hydrocarbon Hydroxylases; Body Weight; Carcinogens; Cholesterol, Dietary; Cocarcinogenesis; Diet; Dietary Fats; Dimethylhydrazines; Indoles; Intestinal Neoplasms; Liver; Male; Methylhydrazines; Organ Size; Rats; Rats, Inbred F344; Triticum | 1986 |
Expression of developmentally regulated crypt cell antigens in human and rat intestinal tumors.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antibodies, Monoclonal; Antigens; Carcinoembryonic Antigen; Colonic Neoplasms; Dimethylhydrazines; Female; Humans; Intestinal Mucosa; Intestinal Neoplasms; Male; Mice; Pregnancy; Rats; Rats, Inbred Strains | 1986 |
Effect of different levels of dietary corn oil and lard during the initiation phase of colon carcinogenesis in F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; Bile Acids and Salts; Body Weight; Colon; Colonic Neoplasms; Corn Oil; Dietary Fats; Dimethylhydrazines; Eating; Male; Oils; Ornithine Decarboxylase; Rats; Rats, Inbred F344 | 1986 |
Selenium and cabbage and colon carcinogenesis in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Body Weight; Brassica; Colonic Neoplasms; Dimethylhydrazines; Eating; Female; Mice; Mice, Inbred ICR; Selenium | 1987 |
A novel approach to the generation and identification of experimental hepatic metastases in a murine model.
Topics: Adenocarcinoma; Animals; Cyclophosphamide; Dimethylhydrazines; Disease Models, Animal; DNA, Recombinant; Double-Blind Method; Immunotherapy; Interleukin-2; Killer Cells, Natural; Liver Neoplasms, Experimental; Melanoma; Methylcholanthrene; Mice; Mice, Inbred C57BL; Pancreatic Neoplasms; Random Allocation; Sarcoma; Spleen; Splenectomy | 1986 |
[Effect of the epidermal growth factor on 1,2-dimethylhydrazine-induced carcinogenesis in the rat intestinal mucosa].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Dimethylhydrazines; Epidermal Growth Factor; Intestinal Mucosa; Intestinal Neoplasms; Male; Peptides; Rats; Submandibular Gland; Transforming Growth Factors | 1987 |
Expression of Ha-ras oncogene product in rat gastrointestinal carcinomas induced by chemical carcinogens.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Methylnitronitrosoguanidine; Oncogene Protein p21(ras); Oncogene Proteins, Viral; Proto-Oncogenes; Rats; Rats, Inbred Strains; Stomach Neoplasms | 1987 |
Transplantable colonic adenocarcinomas in rats.
Topics: Adenocarcinoma; Animals; Ascites; Colonic Neoplasms; Cytoskeletal Proteins; Desmoplakins; Desmosomes; Dimethylhydrazines; Dose-Response Relationship, Drug; Epithelium; Fluorescent Antibody Technique; Membrane Proteins; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Rats; Rats, Inbred F344 | 1987 |
Experimental colorectal cancer as a model of human disease.
Topics: Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Humans; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1987 |
[Inhibition of chemically induced tumors in mice by concanavalin A: reaction and detection of changes in the composition of intestinal glycoconjugates using lectins].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Concanavalin A; Dimethylhydrazines; Female; Glycoproteins; Lectins; Mice; Mice, Inbred ICR | 1987 |
Effect of beef fat on DMH-induced colon tumorigenesis: influence of rat strain and nutrient composition.
Topics: Adenocarcinoma; Animals; Body Weight; Cattle; Cocarcinogenesis; Colonic Neoplasms; Diet; Dietary Fats; Dimethylhydrazines; Energy Intake; Liver Neoplasms; Lung Neoplasms; Male; Meat; Rats; Rats, Inbred F344; Statistics as Topic | 1987 |
Effect of high fat and nutrient depleted diets on colon tumor formation in mice.
Topics: Adenocarcinoma; Adenoma; Animal Nutritional Physiological Phenomena; Animals; Cocarcinogenesis; Colonic Neoplasms; Diet; Dietary Fats; Dimethylhydrazines; Female; Mice | 1987 |
Three new rat colon tumour cell lines from 1,2-dimethylhydrazine induced adenocarcinomas: morphology, karyotype and clonogenicity.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Dimethylhydrazines; Growth Substances; Karyotyping; Male; Neoplastic Stem Cells; Rats; Rats, Inbred Strains | 1987 |
The effect of dietary milk and calcium on experimental colorectal carcinogenesis.
Topics: Adenocarcinoma; Animals; Calcium, Dietary; Colonic Neoplasms; Dimethylhydrazines; Intestinal Obstruction; Male; Milk; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1987 |
Different autochthonous models of colorectal cancer in the rat.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Rats; Rectal Neoplasms | 1986 |
Monitoring the histogenesis of colonic tumors in the Sprague-Dawley rat.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Intestinal Mucosa; Lymphoid Tissue; Male; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Activity of N-[N'-(2-chloroethyl)-N'-nitrosocarbamoyl]-alanine and derivatives against transplantable adenocarcinomata of the mouse colon (MAC).
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alanine; Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylhydrazines; Dipeptides; Glycine; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Nitrosourea Compounds | 1986 |
[Serial endoscopic examinations of 1,2-dimethylhydrazine induced colon tumors in rat and effects of fecal stream].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Colonoscopy; Dimethylhydrazines; Feces; Male; Rats | 1986 |
[Protein kinase activity and phosphorylation of endogenous proteins in the rat colonic mucosa during chemical carcinogenesis].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Intestinal Mucosa; Male; Phosphoproteins; Phosphorylation; Protein Kinases; Proteins; Rats | 1986 |
[Experimental carcinogenesis on the rat intestine induced by combination of 1, 2-dimethylhydrazine and n-methyl-n'-nitro-n-nitrosoguanidine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Male; Methylhydrazines; Methylnitronitrosoguanidine; Rats; Rats, Inbred Strains | 1986 |
Neuroendocrine cells within colorectal tumours induced by dimethylhydrazine. An immunocytochemical study.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Gastrointestinal Hormones; Immunoassay; Male; Neuropeptides; Rats; Rats, Inbred Strains; Rectal Neoplasms | 1986 |
1,2-Dimethylhydrazine-induced alterations in colonic plasma membrane fluidity: restriction to the luminal region.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cell Membrane; Colon; Colonic Neoplasms; Dimethylhydrazines; Drug Resistance; Immunity, Innate; Male; Membrane Fluidity; Membrane Lipids; Methylation; Methylhydrazines; Microvilli; Phospholipids; Rats; Rats, Inbred Strains | 1987 |
Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Allyl Compounds; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Garlic; Methylhydrazines; Mice; Mice, Inbred C57BL; Plants, Medicinal; Sulfides | 1987 |
Changes in cell proliferation and morphology in the large intestine of normal and DMH-treated rats following colostomy.
Topics: Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Colostomy; Dimethylhydrazines; Hyperplasia; Intestine, Large; Male; Mitotic Index; Neoplasm Recurrence, Local; Rats; Rats, Inbred Strains | 1987 |
Stimulation of chemically induced rectal carcinogenesis by chronic ethanol ingestion.
Topics: Adenocarcinoma; Alcohol Oxidoreductases; Animals; Bile Acids and Salts; Colon; Dimethylhydrazines; Ethanol; Intestinal Neoplasms; Intestinal Polyps; Liver; Male; Mucous Membrane; Rats; Rats, Inbred Strains; Rectal Neoplasms; Rectum | 1985 |
Correlation between incidence of 1,2-dimethylhydrazine-induced colon carcinomas and DNA damage in six genetically different mouse strains.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Disease Susceptibility; DNA, Neoplasm; Kidney; Liver; Methylhydrazines; Mice; Mice, Inbred Strains; Species Specificity | 1986 |
Minimal invasive carcinoma of the colon in rats.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Lymphoid Tissue; Male; Neoplasm Invasiveness; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Colon adenocarcinoma-associated nuclear antigens.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Cell Nucleus; Chromatin; Colonic Neoplasms; Dimethylhydrazines; Female; Kidney; Liver; Molecular Weight; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1985 |
Interaction of dietary fat and route of carcinogen administration on 1,2-dimethylhydrazine-induced colon tumorigenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Male; Methylhydrazines; Rats | 1985 |
Adrenergic factors regulating cell division in the colonic crypt epithelium during carcinogenesis and in colonic adenoma and adenocarcinoma.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Cell Division; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Dimethylhydrazines; Male; Mice; Sympathectomy, Chemical; Sympatholytics; Sympathomimetics | 1985 |
Steroid receptors in dimethylhydrazine-induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Female; Male; Rats; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; Rectum | 1985 |
Effects of vitamin E deficiency on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Dimethylhydrazines; Intestinal Neoplasms; Male; Rats; Rats, Inbred Strains; Vitamin E Deficiency | 1985 |
[Development of 1,2-dimethylhydrazine-induced colonic neoplasia in rats and changes in cellular proteins of colonic mucosa].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazines; Electrophoresis, Polyacrylamide Gel; Intestinal Mucosa; Male; Methylhydrazines; Neoplasm Proteins; Rats; Rats, Inbred Strains | 1985 |
[The role of microbial flora in the induction of intestinal tumors in rats].
Topics: Adenocarcinoma; Animals; Bacillus subtilis; Clostridium; Diet; Dimethylhydrazines; Duodenal Neoplasms; Germ-Free Life; Hydrazines; Intestinal Neoplasms; Intestines; Jejunum; Lactobacillus acidophilus; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Rectal Neoplasms; Saccharomyces | 1974 |