dimethylglycine has been researched along with Diabetes Mellitus, Type 2 in 5 studies
dimethylglycine: metabolic product of calcium pangamate; mutagen when mixed with nitrite; RN given refers to parent cpd
N,N-dimethylglycine : An N-methylglycine that is glycine carrying two N-methyl substituents.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Betaine is highly individual in overweight people with diabetes." | 9.20 | Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. ( Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S, 2015) |
| "Betaine is highly individual in overweight people with diabetes." | 5.20 | Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. ( Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S, 2015) |
| "Betaine deficiency is a probable cardiovascular risk factor and a cause of elevated homocysteine." | 2.79 | Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes. ( Chambers, ST; Elmslie, JL; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Parry-Strong, A; Slow, S, 2014) |
| "Patients with type 2 diabetes (n = 34) and control subjects (n = 17) were recruited." | 1.38 | Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study. ( Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Slow, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McEntyre, CJ | 2 |
| Lever, M | 3 |
| Chambers, ST | 3 |
| George, PM | 3 |
| Slow, S | 3 |
| Elmslie, JL | 2 |
| Florkowski, CM | 1 |
| Lunt, H | 2 |
| Krebs, JD | 2 |
| Parry-Strong, A | 1 |
| Magnusson, M | 1 |
| Wang, TJ | 1 |
| Clish, C | 1 |
| Engström, G | 1 |
| Nilsson, P | 1 |
| Gerszten, RE | 1 |
| Melander, O | 1 |
| McGregor, DO | 1 |
| Dellow, WJ | 1 |
| Moazzami, AA | 1 |
| Bondia-Pons, I | 1 |
| Hanhineva, K | 1 |
| Juntunen, K | 1 |
| Antl, N | 1 |
| Poutanen, K | 1 |
| Mykkänen, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Flavanol-rich Dark Chocolate Consumption on Metabolic Profiles Among Obese[NCT04347304] | 74 participants (Anticipated) | Interventional | 2022-03-23 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for dimethylglycine and Diabetes Mellitus, Type 2
2 other studies available for dimethylglycine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Dimethylglycine Deficiency and the Development of Diabetes.
Topics: Aged; Alleles; Diabetes Mellitus, Type 2; Dimethylglycine Dehydrogenase; Female; Genome-Wide Associa | 2015 |
Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.
Topics: Aged; Betaine; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Female; G | 2012 |