Page last updated: 2024-10-18

dimethylglycine and Choline Deficiency

dimethylglycine has been researched along with Choline Deficiency in 2 studies

dimethylglycine: metabolic product of calcium pangamate; mutagen when mixed with nitrite; RN given refers to parent cpd
N,N-dimethylglycine : An N-methylglycine that is glycine carrying two N-methyl substituents.

Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)

Research Excerpts

ExcerptRelevanceReference
"The effect of betaine status on folate deficiency-induced hyperhomocysteinemia was investigated to determine whether folate deficiency impairs homocysteine removal not only by the methionine synthase (MS) pathway but also by the betaine-homocysteine S-methyltransferase (BHMT) pathway."7.78Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats. ( Liu, Y; Liu, YQ; Morita, T; Sugiyama, K, 2012)
"The effect of betaine status on folate deficiency-induced hyperhomocysteinemia was investigated to determine whether folate deficiency impairs homocysteine removal not only by the methionine synthase (MS) pathway but also by the betaine-homocysteine S-methyltransferase (BHMT) pathway."3.78Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats. ( Liu, Y; Liu, YQ; Morita, T; Sugiyama, K, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, Y1
Liu, YQ1
Morita, T1
Sugiyama, K1
Innis, SM1
Hasman, D1

Trials

1 trial available for dimethylglycine and Choline Deficiency

ArticleYear
Evidence of choline depletion and reduced betaine and dimethylglycine with increased homocysteine in plasma of children with cystic fibrosis.
    The Journal of nutrition, 2006, Volume: 136, Issue:8

    Topics: Adolescent; Betaine; Case-Control Studies; Child; Choline Deficiency; Cystic Fibrosis; Homocysteine;

2006

Other Studies

1 other study available for dimethylglycine and Choline Deficiency

ArticleYear
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats.
    Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-

2012
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