Page last updated: 2024-10-18

dimethylglycine and Autism

dimethylglycine has been researched along with Autism in 5 studies

dimethylglycine: metabolic product of calcium pangamate; mutagen when mixed with nitrite; RN given refers to parent cpd
N,N-dimethylglycine : An N-methylglycine that is glycine carrying two N-methyl substituents.

Research Excerpts

ExcerptRelevanceReference
"Oxytocin is expected as a novel therapeutic agent for autism spectrum disorder (ASD) core symptoms."9.41Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms. ( Benner, S; Eriguchi, Y; Kameno, Y; Kasai, K; Kato, Y; Kojima, M; Kosaka, H; Kuroda, M; Kuwabara, H; Munesue, T; Murayama, C; Nishimura, T; Okada, T; Ozaki, N; Tsuchiya, K; Yamasue, H; Yassin, W, 2021)
"N,N-dimethylglycine, a dietary supplement, has been reported to be beneficial in children with autism and pervasive developmental disorder."9.09Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder. ( Cauller, PL; Dodd, M; Kendall, PR; Kern, JK; Mehta, PJ; Miller, VS, 2001)
"Globally, the prevalence of autism is estimated to be less than 1%, especially in high- -income countries."6.82Millennium Nutrient N,N-Dimethylglycine (DMG) and its Effectiveness in Autism Spectrum Disorders. ( Bhardwaj, S; Chopra, C; Dhanjal, DS; Kuca, K; Nepovimova, E; Patocka, J; Plucar, B; Singh, R; Valis, M, 2022)
" The major methodologic weaknesses of the study are thought to be the low dosage of DMG and the small sample size."6.69A double-blind, placebo-controlled, crossover pilot trial of low dose dimethylglycine in patients with autistic disorder. ( Bolman, WM; Richmond, JA, 1999)
"Oxytocin is expected as a novel therapeutic agent for autism spectrum disorder (ASD) core symptoms."5.41Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms. ( Benner, S; Eriguchi, Y; Kameno, Y; Kasai, K; Kato, Y; Kojima, M; Kosaka, H; Kuroda, M; Kuwabara, H; Munesue, T; Murayama, C; Nishimura, T; Okada, T; Ozaki, N; Tsuchiya, K; Yamasue, H; Yassin, W, 2021)
"N,N-dimethylglycine, a dietary supplement, has been reported to be beneficial in children with autism and pervasive developmental disorder."5.09Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder. ( Cauller, PL; Dodd, M; Kendall, PR; Kern, JK; Mehta, PJ; Miller, VS, 2001)
"Globally, the prevalence of autism is estimated to be less than 1%, especially in high- -income countries."2.82Millennium Nutrient N,N-Dimethylglycine (DMG) and its Effectiveness in Autism Spectrum Disorders. ( Bhardwaj, S; Chopra, C; Dhanjal, DS; Kuca, K; Nepovimova, E; Patocka, J; Plucar, B; Singh, R; Valis, M, 2022)
" The major methodologic weaknesses of the study are thought to be the low dosage of DMG and the small sample size."2.69A double-blind, placebo-controlled, crossover pilot trial of low dose dimethylglycine in patients with autistic disorder. ( Bolman, WM; Richmond, JA, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Dhanjal, DS1
Bhardwaj, S1
Chopra, C1
Singh, R1
Patocka, J1
Plucar, B1
Nepovimova, E1
Valis, M1
Kuca, K1
Kato, Y1
Kuwabara, H1
Okada, T1
Munesue, T1
Benner, S1
Kuroda, M1
Kojima, M1
Yassin, W1
Eriguchi, Y1
Kameno, Y1
Murayama, C1
Nishimura, T1
Tsuchiya, K1
Kasai, K1
Ozaki, N1
Kosaka, H1
Yamasue, H1
Xia, RR1
Bolman, WM1
Richmond, JA1
Kern, JK1
Miller, VS1
Cauller, PL1
Kendall, PR1
Mehta, PJ1
Dodd, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Galantamine Versus Placebo in Childhood Autism[NCT00252603]Phase 320 participants Interventional2004-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dimethylglycine and Autism

ArticleYear
Millennium Nutrient N,N-Dimethylglycine (DMG) and its Effectiveness in Autism Spectrum Disorders.
    Current medicinal chemistry, 2022, Volume: 29, Issue:15

    Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Humans; Nutrients; Sarcosine

2022

Trials

3 trials available for dimethylglycine and Autism

ArticleYear
Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms.
    Molecular autism, 2021, 02-23, Volume: 12, Issue:1

    Topics: Administration, Intranasal; Adolescent; Adult; Autistic Disorder; Double-Blind Method; Facial Expres

2021
A double-blind, placebo-controlled, crossover pilot trial of low dose dimethylglycine in patients with autistic disorder.
    Journal of autism and developmental disorders, 1999, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Autistic Disorder; Child; Child, Preschool; Cross-Over Studies; Dose-Response Rel

1999
Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder.
    Journal of child neurology, 2001, Volume: 16, Issue:3

    Topics: Autistic Disorder; Child; Child Development Disorders, Pervasive; Child, Preschool; Double-Blind Met

2001

Other Studies

1 other study available for dimethylglycine and Autism

ArticleYear
Effectiveness of nutritional supplements for reducing symptoms in autism-spectrum disorder: a case report.
    Journal of alternative and complementary medicine (New York, N.Y.), 2011, Volume: 17, Issue:3

    Topics: Autistic Disorder; Child; Child Behavior; Communication; Dietary Supplements; Humans; Interpersonal

2011