dimethyl sulfoxide has been researched along with Tay-Sachs Disease in 1 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Tay-Sachs Disease: An autosomal recessive neurodegenerative disorder characterized by the onset in infancy of an exaggerated startle response, followed by paralysis, dementia, and blindness. It is caused by mutation in the alpha subunit of the HEXOSAMINIDASE A resulting in lipid-laden ganglion cells. It is also known as the B variant (with increased HEXOSAMINIDASE B but absence of hexosaminidase A) and is strongly associated with Ashkenazic Jewish ancestry.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methyl iodide was added to the ganglioside in dimethylsulfoxide." | 1.27 | Modification of sialic acid carboxyl group of ganglioside. ( Handa, S; Nakamura, K, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Handa, S | 1 |
| Nakamura, K | 1 |
1 other study available for dimethyl sulfoxide and Tay-Sachs Disease
| Article | Year |
|---|---|
Modification of sialic acid carboxyl group of ganglioside.
Topics: Animals; Brain Chemistry; Carbohydrates; Cattle; Chemical Phenomena; Chemistry; Cholera Toxin; Chrom | 1984 |