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dimethyl sulfoxide and Subarachnoid Hemorrhage

dimethyl sulfoxide has been researched along with Subarachnoid Hemorrhage in 14 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
" In this study, 160 male Sprague-Dawley (SD) rats were randomly assigned into four groups: Sham, subarachnoid hemorrhage (SAH), SAH treated with dimethyl sulfoxide (DMSO) and SAH treated with GSI1."3.76Gamma-secretase inhibitor (GSI1) attenuates morphological cerebral vasospasm in 24h after experimental subarachnoid hemorrhage in rats. ( Chen, C; Hu, Q; Yan, J; Yang, X; Zhou, C, 2010)
"Our data show that SB203580 reversed cerebral vasospasm by inhibiting the phosphorylation of p38 MAPK in the basilar artery and by suppressing the increase in TNF-α in the basilar artery and CSF after SAH."2.78Intracisternal administration of SB203580, a p38 mitogen-activated protein kinase inhibitor, attenuates cerebral vasospasm via inhibition of tumor-necrosis factor-α. ( Chen, KF; Lin, YX; Pan, YX; Shi, JX; Wu, W; Zhang, X; Zhang, XS; Zhou, XM, 2013)
"Transarterial coil embolization of the ruptured aneurysm and partial Onyx embolization of the shunt led to thrombosis of the aneurysm."1.56Transvenous embolization for craniocervical junction epidural arteriovenous fistula with a pial feeder aneurysm. ( Inoue, T; Kuwamoto, K; Mochizuki, T; Niimi, Y; Okada, Y; Ryu, B; Sato, S; Shima, S; Yoshida, K, 2020)
"Aneurysmal subarachnoid hemorrhage (SAH) is rare in neonates."1.51Onyx embolization of a ruptured anterior inferior cerebellar artery in a neonate. ( Austin, MJ; CreveCoeur, TS; Cross, DT; Miller, BA; Salehi, A; Smyth, MD, 2019)
"Perimedullary arteriovenous fistula (AVF) has shunt on the spinal cord surface and it can be treated with surgery, or endovascular embolization."1.38Endovascular embolization for symptomatic perimedullary AVF and intramedullary AVM: a series and a literature review. ( Jiang, C; Li, Y; Lv, X; Wu, Z; Yang, X, 2012)
"Identifying a source of spontaneous subarachnoid hemorrhage (SAH) or intraventricular hemorrhage (IVH) in patients with negative results on cranial angiographic imaging can be a diagnostic challenge."1.35Onyx embolization of a thoracolumbar perimedullary spinal arteriovenous fistula in an infant presenting with subarachnoid and intraventricular hemorrhage. ( Adamo, MA; Boulos, AS; Deshaies, EM; Kenning, TJ; Waldman, JB, 2009)
"Inflammation could play a role in cerebral vasospasm after subarachnoid hemorrhage (SAH)."1.33Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage. ( Calvert, JW; Yamaguchi, M; Yatsushige, H; Zhang, JH; Zhou, C, 2005)
"Ras contributes to cerebral vasospasm, and inhibitors of Ras FTase may have potential in the management of cerebral vasospasm."1.32Ras protein contributes to cerebral vasospasm in a canine double-hemorrhage model. ( Nanda, A; Yamaguchi, M; Zhang, JH; Zhou, C, 2004)
" No adverse clinical sequelae were noted."1.30A reexamination of the angiotoxicity of superselective injection of DMSO in the swine rete embolization model. ( Alderman, J; Chaloupka, JC; Fink, S; Hammond, R; Huddle, DC; Vinters, HV, 1999)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's8 (57.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Yoshida, K1
Sato, S1
Inoue, T1
Ryu, B1
Shima, S1
Mochizuki, T1
Kuwamoto, K1
Okada, Y1
Niimi, Y1
Kerolus, MG1
Chung, J1
Munich, SA1
Matsuda, Y1
Okada, H1
Lopes, DK1
CreveCoeur, TS1
Salehi, A1
Miller, BA1
Austin, MJ1
Cross, DT1
Smyth, MD1
Suzuki, T1
Okamoto, K1
Genkai, N1
Ito, Y1
Abe, H1
Pan, YX1
Chen, KF1
Lin, YX1
Wu, W1
Zhou, XM1
Zhang, XS1
Zhang, X1
Shi, JX1
Deng, JP1
Zhang, T1
Li, J1
Yu, J1
Zhao, ZW1
Gao, GD1
Kenning, TJ1
Deshaies, EM1
Adamo, MA1
Waldman, JB1
Boulos, AS1
Yang, X2
Chen, C1
Hu, Q1
Yan, J1
Zhou, C3
Lv, X1
Li, Y1
Jiang, C1
Wu, Z1
Kuo, CP1
Lu, CH1
Wen, LL1
Cherng, CH1
Wong, CS1
Borel, CO1
Ju, DT1
Chen, CM1
Wu, CT1
Molyneux, AJ1
Cekirge, S1
Saatci, I1
Gál, G1
Yamaguchi, M2
Nanda, A1
Zhang, JH2
Yatsushige, H1
Calvert, JW1
Chaloupka, JC1
Huddle, DC1
Alderman, J1
Fink, S1
Hammond, R1
Vinters, HV1

Trials

2 trials available for dimethyl sulfoxide and Subarachnoid Hemorrhage

ArticleYear
Intracisternal administration of SB203580, a p38 mitogen-activated protein kinase inhibitor, attenuates cerebral vasospasm via inhibition of tumor-necrosis factor-α.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:5

    Topics: Animals; Basilar Artery; Dimethyl Sulfoxide; Disease Models, Animal; Imidazoles; p38 Mitogen-Activat

2013
Cerebral Aneurysm Multicenter European Onyx (CAMEO) trial: results of a prospective observational study in 20 European centers.
    AJNR. American journal of neuroradiology, 2004, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Aneurysm, Ruptured; Blood Vessel Prosthesis; Cerebral Angiography; Cerebral

2004

Other Studies

12 other studies available for dimethyl sulfoxide and Subarachnoid Hemorrhage

ArticleYear
Transvenous embolization for craniocervical junction epidural arteriovenous fistula with a pial feeder aneurysm.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2020, Volume: 26, Issue:2

    Topics: Aged; Aneurysm, Ruptured; Arteriovenous Fistula; Cerebral Veins; Cervical Atlas; Dimethyl Sulfoxide;

2020
An Onyx tunnel: reconstructive transvenous balloon-assisted Onyx embolization for dural arteriovenous fistula of the transverse-sigmoid sinus.
    Journal of neurosurgery, 2018, Volume: 129, Issue:4

    Topics: Aged; Angioplasty, Balloon; Central Nervous System Vascular Malformations; Cranial Sinuses; Dimethyl

2018
Onyx embolization of a ruptured anterior inferior cerebellar artery in a neonate.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019, Volume: 35, Issue:2

    Topics: Aneurysm, Ruptured; Dimethyl Sulfoxide; Embolization, Therapeutic; Humans; Infant, Newborn; Intracra

2019
Multiple aneurysms on the subarcuate artery arising from the anterior inferior cerebellar artery in a patient with a Borden type I transverse-sigmoid dural arteriovenous fistula manifesting as subarachnoid hemorrhage: A case report.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2019, Volume: 25, Issue:1

    Topics: Aged; Central Nervous System Vascular Malformations; Cerebellar Diseases; Cerebral Angiography; Comp

2019
Treatment of dural arteriovenous fistula by balloon-assisted transarterial embolization with Onyx.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Adolescent; Adult; Angiography, Digital Subtraction; Balloon Occlusion; Central Nervous System Vascu

2013
Onyx embolization of a thoracolumbar perimedullary spinal arteriovenous fistula in an infant presenting with subarachnoid and intraventricular hemorrhage.
    Journal of neurosurgery. Pediatrics, 2009, Volume: 3, Issue:3

    Topics: Arteriovenous Fistula; Cerebral Hemorrhage; Dimethyl Sulfoxide; Embolization, Therapeutic; Female; H

2009
Gamma-secretase inhibitor (GSI1) attenuates morphological cerebral vasospasm in 24h after experimental subarachnoid hemorrhage in rats.
    Neuroscience letters, 2010, Jan-29, Volume: 469, Issue:3

    Topics: Amyloid Precursor Protein Secretases; Animals; Brain; Dimethyl Sulfoxide; Enzyme Inhibitors; Male; N

2010
Endovascular embolization for symptomatic perimedullary AVF and intramedullary AVM: a series and a literature review.
    Neuroradiology, 2012, Volume: 54, Issue:4

    Topics: Adolescent; Adult; Aged; Arteriovenous Fistula; Arteriovenous Malformations; Central Nervous System

2012
Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Basilar Artery; Blotting, Western; Brain; Catalase

2011
Ras protein contributes to cerebral vasospasm in a canine double-hemorrhage model.
    Stroke, 2004, Volume: 35, Issue:7

    Topics: Alkyl and Aryl Transferases; Animals; Dimethyl Sulfoxide; Dogs; Enzyme Inhibitors; Farnesyltranstran

2004
Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage.
    Stroke, 2005, Volume: 36, Issue:7

    Topics: Angiography; Animals; Anthracenes; Blotting, Western; Cytokines; Dimethyl Sulfoxide; Dogs; Dose-Resp

2005
A reexamination of the angiotoxicity of superselective injection of DMSO in the swine rete embolization model.
    AJNR. American journal of neuroradiology, 1999, Volume: 20, Issue:3

    Topics: Angiography, Digital Subtraction; Animals; Arteries; Blood Pressure; Catheterization, Peripheral; Ce

1999