Page last updated: 2024-10-18

dimethyl sulfoxide and Stroke

dimethyl sulfoxide has been researched along with Stroke in 11 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"Stroke was induced in rats by embolizing a preformed clot into the middle cerebral artery."5.34Combination therapy of rosiglitazone, a peroxisome proliferator-activated receptor-gamma ligand, and NMDA receptor antagonist (MK-801) on experimental embolic stroke in rats. ( Allahtavakoli, M; Pourshanazari, A; Roohbakhsh, A; Shabanzadeh, A, 2007)
"The safety and tolerability of a free radical scavenger with Na+ channel blocking activity (dimethyl sulfoxide (DMSO)) combined with a glycolytic intermediate and high energy substrate (fructose 1,6-disphosphate (FDP)) were assessed in a mostly elderly patient group presenting with acute and subacute ischemic stroke."5.10Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial. ( de la Torre, JC; Demir, S; Karaça, M; Kiliç, E; Yazici, B, 2002)
"Endovascular occlusion of cerebral arteriovenous malformations (AVM) is often utilized as adjunctive therapy in combination with radiosurgery or microsurgery."2.50Embolization-induced angiogenesis in cerebral arteriovenous malformations. ( Buell, TJ; Ding, D; Liu, KC; Starke, RM; Webster Crowley, R, 2014)
"Neurobehavioral testing, infarct volume quantification, and hippocampal neuronal survival were employed to determine severity of stroke."1.91Post-stroke periodic estrogen receptor-beta agonist improves cognition in aged female rats. ( Bassett, ZQ; Bramlett, HM; Dave, KR; Patel, SH; Perez-Pinzon, MA; Pradhyumnan, H; Raval, AP; Reddy, V; Zhao, W, 2023)
"Vertebral arteriovenous fistulas (VAVF) are infrequent lesions characterized by abnormal communication of the extracranial vertebral artery or one of its branches to the surrounding venous plexuses, without the presence of any intervening vessels."1.40Spontaneous vertebral arteriovenous fistula causing cervical myelopathy and acute ischemic strokes treated by endovascular balloon-assisted coiling and Onyx embolization. ( Hui, F; Hussain, MS; Jaffari, N; John, S; Lu, M, 2014)
" The aim of this study was to clarify differences in outcomes owing to different dosing regimens and the pharmacokinetic profile of progesterone, particularly in relation to brain levels."1.38Progesterone pharmacokinetics in the mouse: implications for potential stroke therapy. ( Kendall, DA; Ray, D; Wong, R, 2012)
"Stroke was induced in rats by embolizing a preformed clot into the middle cerebral artery."1.34Combination therapy of rosiglitazone, a peroxisome proliferator-activated receptor-gamma ligand, and NMDA receptor antagonist (MK-801) on experimental embolic stroke in rats. ( Allahtavakoli, M; Pourshanazari, A; Roohbakhsh, A; Shabanzadeh, A, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Pradhyumnan, H1
Reddy, V1
Bassett, ZQ1
Patel, SH1
Zhao, W1
Dave, KR1
Perez-Pinzon, MA1
Bramlett, HM1
Raval, AP1
Mirabet, V1
García, D1
Roca, A1
Quiroz, AR1
Antón, J1
Rodríguez-Cadarso, M1
Ocete, D1
Aranda, L1
Melero, A1
Guillot, AJ1
Yagüe, N1
Guillén, I1
Botella, C1
John, S1
Jaffari, N1
Lu, M1
Hussain, MS1
Hui, F1
Buell, TJ1
Ding, D1
Starke, RM1
Webster Crowley, R1
Liu, KC1
Ichijo, M1
Ishibashi, S1
Li, F1
Yui, D1
Miki, K1
Mizusawa, H1
Yokota, T1
González-López, TJ1
Sánchez-Guijo, FM1
Ortín, A1
Crusoe, E1
Cordoba, I1
Corral, M1
Vazquez, L1
Caballero, MD1
Wong, R1
Ray, D1
Kendall, DA1
Chen-Plotkin, AS1
Vossel, KA1
Samuels, MA1
Chen, MH1
Savolainen, H1
Allahtavakoli, M1
Shabanzadeh, A1
Roohbakhsh, A1
Pourshanazari, A1
Karaça, M1
Kiliç, E1
Yazici, B1
Demir, S1
de la Torre, JC1

Reviews

1 review available for dimethyl sulfoxide and Stroke

ArticleYear
Embolization-induced angiogenesis in cerebral arteriovenous malformations.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:11

    Topics: Antigens, CD; Cell Hypoxia; Cerebrovascular Circulation; Combined Modality Therapy; Dimethyl Sulfoxi

2014

Trials

1 trial available for dimethyl sulfoxide and Stroke

ArticleYear
Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial.
    Neurological research, 2002, Volume: 24, Issue:1

    Topics: Adult; Aged; Aging; Brain; Brain Edema; Cerebrovascular Circulation; Dimethyl Sulfoxide; Drug Combin

2002

Other Studies

9 other studies available for dimethyl sulfoxide and Stroke

ArticleYear
Post-stroke periodic estrogen receptor-beta agonist improves cognition in aged female rats.
    Neurochemistry international, 2023, Volume: 165

    Topics: Animals; Cognition; Dimethyl Sulfoxide; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta;

2023
Cranioplasty with Autologous Bone Flaps Cryopreserved with Dimethylsulphoxide: Does Tissue Processing Matter.
    World neurosurgery, 2021, Volume: 149

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Autografts; Bone Resorption; Brain Edema; Brain Injuries,

2021
Spontaneous vertebral arteriovenous fistula causing cervical myelopathy and acute ischemic strokes treated by endovascular balloon-assisted coiling and Onyx embolization.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:1

    Topics: Arteriovenous Fistula; Balloon Occlusion; Blood Vessel Prosthesis; Dimethyl Sulfoxide; Embolization,

2014
Sphingosine-1-Phosphate Receptor-1 Selective Agonist Enhances Collateral Growth and Protects against Subsequent Stroke.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Endothelial Cells; Male; Mice; Oxadiazoles; Rec

2015
Ischemic stroke associated with the infusion of DMSO-cryopreserved auto-PBSCs.
    Bone marrow transplantation, 2011, Volume: 46, Issue:7

    Topics: Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Hematopoietic Stem Cell Transplantation

2011
Progesterone pharmacokinetics in the mouse: implications for potential stroke therapy.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:11

    Topics: Animals; Brain; Dimethyl Sulfoxide; Enzyme-Linked Immunosorbent Assay; Half-Life; Infusion Pumps, Im

2012
Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation.
    Neurology, 2007, Mar-13, Volume: 68, Issue:11

    Topics: Brain Injuries; Dimethyl Sulfoxide; Female; Humans; Male; Middle Aged; Myocardial Infarction; Stem C

2007
Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation.
    Neurology, 2007, Jul-31, Volume: 69, Issue:5

    Topics: Dimethyl Sulfoxide; Heme; Humans; Hypoxia-Ischemia, Brain; Mitochondria; Myocardial Infarction; Stem

2007
Combination therapy of rosiglitazone, a peroxisome proliferator-activated receptor-gamma ligand, and NMDA receptor antagonist (MK-801) on experimental embolic stroke in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:5

    Topics: Animals; Behavior, Animal; Blood Coagulation; Brain; Cerebral Infarction; Dimethyl Sulfoxide; Dizoci

2007