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dimethyl sulfoxide and Stomach Ulcer

dimethyl sulfoxide has been researched along with Stomach Ulcer in 12 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
"Effects of treatment with free radical scavengers in the healing process of acetic acid-induced gastric ulcer on the ulcer aggravation induced by indomethacin were investigated."7.69Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995)
"Effects of treatment with free radical scavengers in the healing process of acetic acid-induced gastric ulcer on the ulcer aggravation induced by indomethacin were investigated."3.69Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. ( Kondo, M; Matsuyama, K; Naito, Y; Nishimura, S; Yagi, N; Yoshikawa, T, 1995)
" Intraperitoneal reserpine (5 mg/kg every day for 5 days) produced chronic gastric ulceration in all rats after 4 weeks."3.67Role of oxygen-derived free radicals in the mechanism of chronic gastric ulceration in the rat: implications for cytoprotection. ( Salim, AS, 1989)
" CT-3 was devoid of GI ulceration when administered with DMSO either acutely at doses below 100 mg/kg or chronically at a dosage of 30 mg/kg/day for 5 days."1.301',1'-Dimethylheptyl-delta-8-tetrahydrocannabinol-11-oic acid: a novel, orally effective cannabinoid with analgesic and anti-inflammatory properties. ( Dajani, EZ; Dajani, NE; Dayton, MT; Larsen, KR; Mir, GN; Neeleman, SD; Shahwan, TG; Taylor, J; Taylor, MS, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's5 (41.67)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amirshahrokhi, K1
Khalili, AR1
Navarro, L1
Rosell, G1
Sánchez, S1
Boixareu, N1
Pors, K1
Pouplana, R1
Campanera, JM1
Pujol, MD1
Hung, CR2
Wang, PS1
Naito, Y1
Yoshikawa, T1
Matsuyama, K1
Nishimura, S1
Yagi, N1
Kondo, M1
Dajani, EZ1
Larsen, KR1
Taylor, J1
Dajani, NE1
Shahwan, TG1
Neeleman, SD1
Taylor, MS1
Dayton, MT1
Mir, GN1
Uchida, M1
Takayama, M1
Kato, Y1
Tsuchiya, S1
Horie, S1
Watanabe, K1
Salim, AS3
Mutoh, H1
Ota, S1
Hiraishi, H1
Ivey, KJ1
Terano, A1
Sugimoto, T1
Smith, SM1
Kvietys, PR1

Reviews

1 review available for dimethyl sulfoxide and Stomach Ulcer

ArticleYear
Gastric ulcers: role of oxygen radicals.
    Critical care medicine, 1988, Volume: 16, Issue:9

    Topics: Animals; Cats; Dimethyl Sulfoxide; Disease Models, Animal; Ethanol; Gastric Mucosa; Ischemia; Lipid

1988

Trials

1 trial available for dimethyl sulfoxide and Stomach Ulcer

ArticleYear
Scavenging free radicals to prevent stress-induced gastric mucosal injury.
    Lancet (London, England), 1989, Dec-09, Volume: 2, Issue:8676

    Topics: Adult; Allopurinol; Dimethyl Sulfoxide; Female; Free Radicals; Gastric Mucosa; Humans; Hydroxides; H

1989

Other Studies

10 other studies available for dimethyl sulfoxide and Stomach Ulcer

ArticleYear
Methylsulfonylmethane is effective against gastric mucosal injury.
    European journal of pharmacology, 2017, Sep-15, Volume: 811

    Topics: Animals; Cytokines; Dimethyl Sulfoxide; Dinoprostone; Gastric Mucosa; Gene Expression Regulation; Ma

2017
Synthesis and biological properties of aryl methyl sulfones.
    Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimet

2018
Gastric oxidative stress and hemorrhagic ulcer in Salmonella typhimurium-infected rats.
    European journal of pharmacology, 2004, Apr-26, Volume: 491, Issue:1

    Topics: Allopurinol; Animals; Anti-Infective Agents; Dimethyl Sulfoxide; Free Radical Scavengers; Gastric Ju

2004
Modulation of gastric hemorrhage and ulceration by oxidative stress and histamine release in Salmonella typhimurium-infected rats.
    Inflammopharmacology, 2005, Volume: 13, Issue:1-3

    Topics: Allopurinol; Animals; Antioxidants; Dimethyl Sulfoxide; Disease Models, Animal; Gastric Juice; Gastr

2005
Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:9

    Topics: Acetates; Acetic Acid; Allopurinol; Animals; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Free Rad

1995
1',1'-Dimethylheptyl-delta-8-tetrahydrocannabinol-11-oic acid: a novel, orally effective cannabinoid with analgesic and anti-inflammatory properties.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:1

    Topics: Administration, Oral; Analgesia; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Ag

1999
A novel method to produce extensive gastric antral ulcer in rats: pharmacological factors involved in the etiology of antral ulceration.
    Journal of physiology, Paris, 1999, Volume: 93, Issue:5

    Topics: Animals; Dimethyl Sulfoxide; Ditiocarb; Gastric Mucosa; Glutathione; Humans; Hydrochloric Acid; Male

1999
A possible new approach to the problem of refractory peptic ulceration. A role for free radical scavengers?
    Scottish medical journal, 1991, Volume: 36, Issue:1

    Topics: Adult; Allopurinol; Chronic Disease; Cimetidine; Dimethyl Sulfoxide; Duodenal Ulcer; Female; Free Ra

1991
Reduced glutathione protects cultured gastric mucosal cells from suckling rats against acid.
    The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 1

    Topics: Acids; Animals; Animals, Newborn; Catalase; Cells, Cultured; Cysteine; Diamide; Dimethyl Sulfoxide;

1991
Role of oxygen-derived free radicals in the mechanism of chronic gastric ulceration in the rat: implications for cytoprotection.
    Digestion, 1989, Volume: 43, Issue:1-2

    Topics: Allopurinol; Animals; Chronic Disease; Dimethyl Sulfoxide; Female; Free Radicals; Gastric Acid; Hydr

1989