dimethyl sulfoxide has been researched along with Skin Ulcer in 31 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Skin Ulcer: An ULCER of the skin and underlying tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to make an investigation on skin ulcer induced by Mitomycin C extravasation, the preventive measures were undergone by the following ex-periment." | 7.69 | [An experimental investigation on preventive measures of skin ulcers induced by extravascular mitomycin C]. ( Chen, M; Wang, GH; Zhang, XQ, 1995) |
| " Based on our previous work in the rat, we hypothesized that the free radical scavengers dimethyl sulfoxide (DMSO) and vitamin C prevent doxorubicin-induced skin ulcers in white swine." | 7.69 | Protective effect of doxorubicin in vitamin C or dimethyl sulfoxide against skin ulceration in the pig. ( Barrie, R; Hajarizadeh, H; Lebredo, L; Woltering, EA, 1994) |
| "Necrosis was evident in the DXR-treated group and some slides showed necrosis involving the fascia." | 5.36 | Melatonin ameliorates doxorubicin-induced skin necrosis in rats. ( Citak, EC; Karslioglu, Y; Kesik, V; Kismet, E; Koseoglu, V; Kurt, B; Tunc, T, 2010) |
| "The topical treatment with dimethyl sulfoxide (DMSO) and/or alpha-tocopherol (alpha-T) is widely used in order to prevent the local complications of extravasation of cytostatic drugs and protect patients against skin ulceration." | 3.74 | Semisolid formulations containing dimethyl sulfoxide and alpha-tocopherol for the treatment of extravasation of antiblastic agents. ( Ardovino, P; Botta, C; Casiraghi, A; Gattini, A; Minghetti, P; Montanari, L, 2007) |
| "In order to make an investigation on skin ulcer induced by Mitomycin C extravasation, the preventive measures were undergone by the following ex-periment." | 3.69 | [An experimental investigation on preventive measures of skin ulcers induced by extravascular mitomycin C]. ( Chen, M; Wang, GH; Zhang, XQ, 1995) |
| " Based on our previous work in the rat, we hypothesized that the free radical scavengers dimethyl sulfoxide (DMSO) and vitamin C prevent doxorubicin-induced skin ulcers in white swine." | 3.69 | Protective effect of doxorubicin in vitamin C or dimethyl sulfoxide against skin ulceration in the pig. ( Barrie, R; Hajarizadeh, H; Lebredo, L; Woltering, EA, 1994) |
| "Necrosis was evident in the DXR-treated group and some slides showed necrosis involving the fascia." | 1.36 | Melatonin ameliorates doxorubicin-induced skin necrosis in rats. ( Citak, EC; Karslioglu, Y; Kesik, V; Kismet, E; Koseoglu, V; Kurt, B; Tunc, T, 2010) |
| "A series of toxicologic and pharmacokinetic studies were performed in BALB/c mice administered intradermal (ID) mitomycin C (MMC) at doses of ." | 1.27 | Mitomycin C skin toxicity studies in mice: reduced ulceration and altered pharmacokinetics with topical dimethyl sulfoxide. ( Dorr, RT; Keller, JH; Liddil, JD; Soble, MJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (61.29) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uzunoglu, S | 1 |
| Cosar, R | 1 |
| Cicin, I | 1 |
| Ibis, K | 1 |
| Demiralay, E | 1 |
| Benlier, E | 1 |
| Erdogan, B | 1 |
| Kandulu, H | 1 |
| Ozen, A | 1 |
| Altaner, S | 1 |
| Kesik, V | 2 |
| Yuksel, R | 1 |
| Yigit, N | 1 |
| Saldir, M | 1 |
| Karabacak, E | 1 |
| Erdem, G | 1 |
| Babacan, O | 1 |
| Gulgun, M | 1 |
| Korkmazer, N | 1 |
| Bayrak, Z | 1 |
| Kurt, B | 1 |
| Tunc, T | 1 |
| Karslioglu, Y | 1 |
| Citak, EC | 1 |
| Kismet, E | 1 |
| Koseoglu, V | 1 |
| Langer, SW | 1 |
| Schrijvers, DL | 1 |
| SCHERBEL, AL | 2 |
| MCCORMACK, LJ | 1 |
| POPPO, MJ | 1 |
| Casiraghi, A | 1 |
| Ardovino, P | 1 |
| Minghetti, P | 1 |
| Botta, C | 1 |
| Gattini, A | 1 |
| Montanari, L | 1 |
| Bardychev, MS | 3 |
| Okano, T | 1 |
| Ohnuma, T | 1 |
| Efremidis, A | 1 |
| Holland, JF | 1 |
| Olver, IN | 1 |
| Schwarz, MA | 1 |
| Dorr, RT | 2 |
| Alberts, DS | 1 |
| Desai, MH | 1 |
| Teres, D | 1 |
| Svingen, BA | 1 |
| Powis, G | 1 |
| Appel, PL | 1 |
| Scott, M | 1 |
| Bertelli, G | 2 |
| Gozza, A | 1 |
| Forno, GB | 1 |
| Vidili, MG | 1 |
| Silvestro, S | 1 |
| Venturini, M | 1 |
| Del Mastro, L | 1 |
| Garrone, O | 1 |
| Rosso, R | 1 |
| Dini, D | 1 |
| Wang, GH | 1 |
| Chen, M | 1 |
| Zhang, XQ | 1 |
| Hajarizadeh, H | 1 |
| Lebredo, L | 2 |
| Barrie, R | 2 |
| Woltering, EA | 2 |
| Sarkisian, IuKh | 1 |
| Kir'ianov, IIu | 1 |
| Mikhalchenko, VA | 1 |
| Barybin, AS | 1 |
| Gretskiĭ, VM | 1 |
| Petrik, VD | 2 |
| Iakovleva, ND | 1 |
| Binnick, SA | 1 |
| Shore, SS | 1 |
| Corman, A | 1 |
| Fleischmajer, R | 2 |
| Miranda-Tirado, R | 1 |
| Birgin, SKh | 1 |
| Afanas'ev, AN | 1 |
| El'kin, GI | 1 |
| Rustemova, GR | 1 |
| Malamud, MIa | 1 |
| Osipova, VV | 1 |
| Soble, MJ | 1 |
| Liddil, JD | 1 |
| Keller, JH | 1 |
| Ludwig, CU | 1 |
| Stoll, HR | 1 |
| Obrist, R | 1 |
| Obrecht, JP | 1 |
| Lishner, M | 1 |
| Lang, R | 1 |
| Kedar, I | 1 |
| Ravid, M | 1 |
| Williams, HJ | 1 |
| Furst, DE | 1 |
| Dahl, SL | 1 |
| Steen, VD | 1 |
| Marks, C | 1 |
| Alpert, EJ | 1 |
| Henderson, AM | 1 |
| Samuelson, CO | 1 |
| Dreyfus, JN | 1 |
| Weinstein, A | 1 |
| Glaser, FH | 1 |
| Klaua, M | 1 |
3 reviews available for dimethyl sulfoxide and Skin Ulcer
| Article | Year |
|---|---|
Extravasation: a dreaded complication of chemotherapy.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Dimethyl Sulfoxide; Doxorubicin; Extravasa | 2003 |
[Treatment of the radiation injuries occurring in the radiotherapy of malignant tumors].
Topics: Dermatologic Surgical Procedures; Dimethyl Sulfoxide; Heart; Humans; Intestines; Lung; Lymphatic Met | 1984 |
Prevention and management of extravasation of cytotoxic drugs.
Topics: Adrenal Cortex Hormones; Animals; Antidotes; Combined Modality Therapy; Dimethyl Sulfoxide; Extravas | 1995 |
5 trials available for dimethyl sulfoxide and Skin Ulcer
| Article | Year |
|---|---|
Topical dimethylsulfoxide for the prevention of soft tissue injury after extravasation of vesicant cytotoxic drugs: a prospective clinical study.
Topics: Administration, Topical; Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Connective T | 1995 |
[Use of dimexide (dimethyl sulfoxide) in the overall treatment of local radiation complications].
Topics: Aged; Clinical Trials as Topic; Dimethyl Sulfoxide; Drug Evaluation; Drug Therapy, Combination; Huma | 1977 |
[Use of baliz for the treatment of late radiation skin ulcers].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Clinical Trials as Topic; Dimethyl Sul | 1979 |
Treatment of diabetic perforating ulcers (mal perforant) with local dimethylsulfoxide.
Topics: Aged; Clinical Trials as Topic; Diabetic Neuropathies; Dimethyl Sulfoxide; Female; Foot Diseases; Hu | 1985 |
Double-blind, multicenter controlled trial comparing topical dimethyl sulfoxide and normal saline for treatment of hand ulcers in patients with systemic sclerosis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Clinical Trials as Topic; Dimethyl Sulfoxide; Doub | 1985 |
23 other studies available for dimethyl sulfoxide and Skin Ulcer
| Article | Year |
|---|---|
Carnitine or dimethyl sulfoxide, or both, for the treatment of anthracycline extravasation in rats.
Topics: Administration, Topical; Animals; Anthracyclines; Carnitine; Dimethyl Sulfoxide; Disease Models, Ani | 2013 |
Ozone Ameliorates Doxorubicine-Induced Skin Necrosis - results from an animal model.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Biopsy; Dimethyl Sulfoxide; Disease Models, Anim | 2016 |
Melatonin ameliorates doxorubicin-induced skin necrosis in rats.
Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Glutathione Peroxidase; Male; Malondialdehyde; Melatonin; | 2010 |
RE: Kesik et al: melatonin ameliorates doxorubicin-induced skin necrosis in rats.
Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Doxorubicin; Melatonin; Necrosis; Rats; Sensiti | 2010 |
ALTERATION OF COLLAGEN IN GENERALIZED SCLERODERMA (PROGRESSIVE SYSTEMIC SCLEROSIS) AFTER TREATMENT WITH DIMETHYL SULFOXIDE: PRELIMINARY REPORT.
Topics: Collagen; Dimethyl Sulfoxide; Drug Therapy; Fingers; Humans; Pathology; Scleroderma, Diffuse; Sclero | 1965 |
Semisolid formulations containing dimethyl sulfoxide and alpha-tocopherol for the treatment of extravasation of antiblastic agents.
Topics: Administration, Topical; alpha-Tocopherol; Anthracyclines; Antioxidants; Dimethyl Sulfoxide; Emulsio | 2007 |
The effect of percutaneous dimethyl sulfoxide on cutaneous manifestations of systemic sclerosis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Dimethyl Sulfoxide; Female; Humans; Joints; | 1983 |
Doxorubicin-induced skin ulcer in the piglet.
Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Drug Interactions; Male; Skin Ulcer; Swine; Vitamin E | 1983 |
Use of dimethyl sulfoxide in limiting tissue damage caused by extravasation of doxorubicin.
Topics: Administration, Topical; Dimethyl Sulfoxide; Doxorubicin; Female; Humans; Male; Middle Aged; Skin Ul | 1983 |
Failure of DMSO and vitamin E to prevent doxorubicin skin ulceration in the mouse.
Topics: Administration, Topical; Animals; Dimethyl Sulfoxide; Doxorubicin; Female; Mice; Mice, Inbred BALB C | 1983 |
Prevention of doxorubicin-induced skin ulcers in the rat and pig with dimethyl sulfoxide (DMSO).
Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Male; Rats; Rats, Inbred Strains; Skin Ulcer; Swine | 1982 |
Protection by alpha-tocopherol and dimethylsulfoxide (DMSO) against adriamycin induced skin ulcers in the rat.
Topics: Administration, Topical; Animals; Dimethyl Sulfoxide; Doxorubicin; Male; Rats; Rats, Inbred Strains; | 1981 |
[An experimental investigation on preventive measures of skin ulcers induced by extravascular mitomycin C].
Topics: Animals; Dimethyl Sulfoxide; Extremities; Humans; Mice; Mice, Inbred BALB C; Mitomycin; Skin Ulcer | 1995 |
Protective effect of doxorubicin in vitamin C or dimethyl sulfoxide against skin ulceration in the pig.
Topics: Animals; Ascorbic Acid; Dimethyl Sulfoxide; Doxorubicin; Drug Combinations; Drug Interactions; Incid | 1994 |
[Clinical morphological characteristics of the reparation of an acute radiation ulcer].
Topics: Acute Disease; Administration, Topical; Anabolic Agents; Animals; Anti-Bacterial Agents; Anti-Inflam | 1979 |
Failure of dimethyl sulfoxide in the treatment of scleroderma.
Topics: Adult; Aged; Dimethyl Sulfoxide; Female; Humans; Male; Middle Aged; Scleroderma, Localized; Sclerode | 1977 |
Discussion paper: methodology and techniques in the evaluation of dimethyl sulfoxide for connective tissue disorders.
Topics: Administration, Topical; Dimethyl Sulfoxide; Humans; Hydroxyproline; Plethysmography; Scleroderma, S | 1975 |
Dimethyl sulfoxide therapy in chronic skin ulcers.
Topics: Burns; Chronic Disease; Dermatologic Agents; Diabetes Complications; Dimethyl Sulfoxide; Drug Combin | 1975 |
DMSO protects against adriamycin-induced tissue necrosis.
Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Male; Necrosis; Rats; Rats, Sprague-Dawley; Skin; Skin Ulc | 1992 |
[Treatment of suppurative-necrotic complications of diabetes mellitus].
Topics: Adult; Aged; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; F | 1991 |
Mitomycin C skin toxicity studies in mice: reduced ulceration and altered pharmacokinetics with topical dimethyl sulfoxide.
Topics: Animals; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Female; Kinetics; Mice; Mice, Inbred | 1986 |
Prevention of cytotoxic drug induced skin ulcers with dimethyl sulfoxide (DMSO) and alpha-tocopherole.
Topics: Administration, Cutaneous; Antineoplastic Combined Chemotherapy Protocols; Dimethyl Sulfoxide; Doxor | 1987 |
[Preliminary experiences in the treatment with DMSO fibrous skin changes after percutaneous radiotherapy].
Topics: Dimethyl Sulfoxide; Humans; Radiation Injuries; Radiotherapy; Skin; Skin Diseases; Skin Ulcer | 1970 |