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dimethyl sulfoxide and Rhabdomyosarcoma

dimethyl sulfoxide has been researched along with Rhabdomyosarcoma in 11 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Rhabdomyosarcoma: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)

Research Excerpts

ExcerptRelevanceReference
"To determine whether the local administration of 9,10-dimethyl-1,2-benzanthracene (DMBA) into the hamster maxillary sinus induced carcinoma at the injected site, hamsters were injected with 30 microliters of 0."7.69Induction of carcinomas and sarcomas by 9,10-dimethyl-1,2-benzanthracene administration into the hamster maxillary sinus. ( Harada, K; Kusaka, J; Sato, M; Tsujimoto, H; Yoshida, H; Yura, Y, 1995)
"The effect of dimethyl sulfoxide (DMSO) on the interaction of human cytomegalovirus (HCMV) with host cell was studied."7.67Effect of dimethyl sulfoxide on interaction of human cytomegalovirus with host cell: conversion of a nonproductive state of cell to a productive state for virus replication. ( Hatano, M; Kamiya, S; Ogura, H; Ogura, T; Sato, H; Tanaka, J, 1985)
"Dimethyl sulfoxide has been shown to modulate cell differentiation in cultured human cells."5.29Actin, tropomyosin and alpha-actinin as markers of differentiation in human rhabdomyosarcoma cell lines induced with dimethyl sulfoxide. ( Alvarez, L; Aranega, A; Aranega, AE; Fernandez, JE; Melguizo, C; Prados, J, 1993)
"To determine whether the local administration of 9,10-dimethyl-1,2-benzanthracene (DMBA) into the hamster maxillary sinus induced carcinoma at the injected site, hamsters were injected with 30 microliters of 0."3.69Induction of carcinomas and sarcomas by 9,10-dimethyl-1,2-benzanthracene administration into the hamster maxillary sinus. ( Harada, K; Kusaka, J; Sato, M; Tsujimoto, H; Yoshida, H; Yura, Y, 1995)
"The effect of dimethyl sulfoxide (DMSO) on the interaction of human cytomegalovirus (HCMV) with host cell was studied."3.67Effect of dimethyl sulfoxide on interaction of human cytomegalovirus with host cell: conversion of a nonproductive state of cell to a productive state for virus replication. ( Hatano, M; Kamiya, S; Ogura, H; Ogura, T; Sato, H; Tanaka, J, 1985)
"A combination of the radiosensitizer, metronidazole, and the radioprotector, dimethyl sulfoxide (DMSO), was tested for its effects on the radiation tolerance of rat skin and on the radiosensitivity of the BA1112 rhabdomyosarcoma."3.66Effect of combined metronidazole and DMSO on tumour control and skin tolerance in the rat. ( Fischer, JJ; Lo, PS; Moulder, JE, 1978)
"Dimethyl sulfoxide added to cultures first treated with 5-iododeoxyuridine increased C-type virus production approximately tenfold in a human rhabdomyosarcoma cell line."3.65Activation of viruses in human tumors by 5-iododeoxyuridine and dimethyl sulfoxide. ( Ben, T; Draycott, C; Kasnic, G; Stewart, SE, 1972)
"Rhabdomyosarcomas have been classified on the basis of their degree of differentiation, a feature closely related with their response to chemotherapy."1.29Creatine kinase isoenzymes as markers of differentiation in rhabdomyosarcoma cells in culture. ( Alvarez, L; Aránega, A; Fernández, JE; Melguizo, C; Prados, J; Rodríguez, F, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keros, V1
Hultenby, K1
Borgström, B1
Fridström, M1
Jahnukainen, K1
Hovatta, O1
Yura, Y1
Tsujimoto, H1
Kusaka, J1
Harada, K1
Yoshida, H1
Sato, M1
Fernández, JE2
Prados, J3
Melguizo, C3
Rodríguez, F1
Alvarez, L3
Aránega, A3
Velez, C1
Aranega, AE2
Moulder, JE2
Lo, PS2
Fischer, JJ2
Gerharz, CD1
Gabbert, HE1
Engers, R1
Ramp, U1
Mayer, H1
Luley, C1
Tanaka, J1
Kamiya, S1
Ogura, T1
Sato, H1
Ogura, H1
Hatano, M1
Okabe, H1
Gilden, RV1
Hatanaka, M1
Stewart, SE1
Kasnic, G1
Draycott, C1
Ben, T1

Other Studies

11 other studies available for dimethyl sulfoxide and Rhabdomyosarcoma

ArticleYear
Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment.
    Human reproduction (Oxford, England), 2007, Volume: 22, Issue:5

    Topics: Adolescent; beta-Thalassemia; Cells, Cultured; Child; Child, Preschool; Cryopreservation; Cryoprotec

2007
Induction of carcinomas and sarcomas by 9,10-dimethyl-1,2-benzanthracene administration into the hamster maxillary sinus.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell

1995
Creatine kinase isoenzymes as markers of differentiation in rhabdomyosarcoma cells in culture.
    Pathology, research and practice, 1994, Volume: 190, Issue:12

    Topics: Biomarkers, Tumor; Cell Differentiation; Creatine Kinase; Dimethyl Sulfoxide; Humans; Isoenzymes; Rh

1994
Influence of dimethyl sulphoxide on intermediate filament proteins in human rhabdomyosarcoma cell lines: modulation at subcellular level.
    The Histochemical journal, 1994, Volume: 26, Issue:6

    Topics: Blotting, Western; Cell Fractionation; Cell Transformation, Neoplastic; Cytoskeleton; Densitometry;

1994
Actin, tropomyosin and alpha-actinin as markers of differentiation in human rhabdomyosarcoma cell lines induced with dimethyl sulfoxide.
    Cellular and molecular biology (Noisy-le-Grand, France), 1993, Volume: 39, Issue:5

    Topics: Actinin; Actins; Biomarkers; Blotting, Western; Cell Differentiation; Cell Line; Cytoplasm; Dimethyl

1993
Effect of the radioprotective drugs MEA, DMSO, and WR-2721 on tumor control and skin tolerance in the rat.
    Cancer treatment reports, 1977, Volume: 61, Issue:5

    Topics: Amifostine; Animals; Dimethyl Sulfoxide; Female; Male; Mercaptoethylamines; Neoplasms, Experimental;

1977
Effect of combined metronidazole and DMSO on tumour control and skin tolerance in the rat.
    The British journal of cancer. Supplement, 1978, Volume: 3

    Topics: Animals; Dimethyl Sulfoxide; Metronidazole; Radiation Dosage; Radiation Tolerance; Rats; Rhabdomyosa

1978
Heterogeneous response to differentiation induction with different polar compounds in a clonal rat rhabdomyosarcoma cell line (BA-HAN-1C).
    British journal of cancer, 1989, Volume: 60, Issue:4

    Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Fusi

1989
Effect of dimethyl sulfoxide on interaction of human cytomegalovirus with host cell: conversion of a nonproductive state of cell to a productive state for virus replication.
    Virology, 1985, Oct-30, Volume: 146, Issue:2

    Topics: Antigens, Viral; Cell Division; Cell Line; Cytomegalovirus; Dimethyl Sulfoxide; DNA; DNA-Directed DN

1985
RD 114 virus-specific sequences in feline cellular RNA: detection and characterization.
    Journal of virology, 1973, Volume: 12, Issue:5

    Topics: Animals; Base Sequence; Cats; Cattle; Cell Line; Cells, Cultured; Centrifugation, Density Gradient;

1973
Activation of viruses in human tumors by 5-iododeoxyuridine and dimethyl sulfoxide.
    Science (New York, N.Y.), 1972, Jan-14, Volume: 175, Issue:4018

    Topics: Adenocarcinoma; Cells, Cultured; Deoxyuridine; Dimethyl Sulfoxide; Endoplasmic Reticulum; Humans; In

1972