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dimethyl sulfoxide and Proteinuria

dimethyl sulfoxide has been researched along with Proteinuria in 20 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"The hydroxyl radical scavengers dimethylthiourea (DMTU), sodium benzoate, and dimethylsulfoxide (DMSO) were administered to rats before doxorubicin hydrochloride (ADR) (5 mg/kg, IV) to probe the role of free radicals in mediating proteinuria in doxorubicin hydrochloride nephrosis (AN)."7.68Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea. ( Houser, MT; Milner, LS; Wei, SH, 1991)
"A single intravenous injection of puromycin aminonucleoside (PAN) results in marked proteinuria and glomerular morphological changes that are similar to minimal change disease in humans."7.67Evidence suggesting a role for hydroxyl radical in puromycin aminonucleoside-induced proteinuria. ( Shah, SV; Thakur, V; Walker, PD, 1988)
"The effect of treatment with indomethacin on the ability of dimethyl sulfoxide (DMSO) to reduce proteinuria in rats with passive Heymann's nephritis (PHN) was studied."7.67Interactions of dimethyl sulfoxide and nonsteroidal anti-inflammatory agents in passive Heymann's nephritis. ( Fong, JS; Goodyer, PR; Kaplan, BS; Lotan, D; Mills, M; Milner, LS, 1986)
"Colchicine was given to rats in the heterologous phase of passive Heymann nephritis to see whether this drug could reduce proteinuria."7.67Colchicine reduces proteinuria in passive Heymann nephritis. ( Fong, JS; Goodyer, PR; Kaplan, BS; Lotan, D; Mills, M; Milner, LS, 1987)
"8 mmol/kg) was characterized by diuresis, transiently increased proteinuria, glucosuria and hematuria elevated kidney weight and reduced tetraethylammonium (TEA) uptake by renal cortical slices, and was not as marked as nephrotoxicity induced by NDHS (0."3.69Nephrotoxicity of N-(3-bromophenyl)-2-hydroxysuccinimide: role of halogen groups in the nephrotoxic potential of N-(halophenyl) succinimides. ( Anestis, DK; Brown, PI; Hawco, NM; Hong, SK; Rankin, GO; Valentovic, MA, 1996)
"The hydroxyl radical scavengers dimethylthiourea (DMTU), sodium benzoate, and dimethylsulfoxide (DMSO) were administered to rats before doxorubicin hydrochloride (ADR) (5 mg/kg, IV) to probe the role of free radicals in mediating proteinuria in doxorubicin hydrochloride nephrosis (AN)."3.68Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea. ( Houser, MT; Milner, LS; Wei, SH, 1991)
"Passive Heymann nephritis, a model of immune complex nephritis, was produced in rats by injection of rabbit antibrush border membrane vesicle antibodies to examine the effect of treatment of epimembranous glomerulonephritis with dimethyl sulfoxide."3.67Reduction of protein excretion by dimethyl sulfoxide in rats with passive Heymann nephritis. ( de Chadarevian, JP; Fong, JS; Goodyer, PR; Kaplan, BS; Lotan, D, 1984)
"A single intravenous injection of puromycin aminonucleoside (PAN) results in marked proteinuria and glomerular morphological changes that are similar to minimal change disease in humans."3.67Evidence suggesting a role for hydroxyl radical in puromycin aminonucleoside-induced proteinuria. ( Shah, SV; Thakur, V; Walker, PD, 1988)
"The effect of treatment with indomethacin on the ability of dimethyl sulfoxide (DMSO) to reduce proteinuria in rats with passive Heymann's nephritis (PHN) was studied."3.67Interactions of dimethyl sulfoxide and nonsteroidal anti-inflammatory agents in passive Heymann's nephritis. ( Fong, JS; Goodyer, PR; Kaplan, BS; Lotan, D; Mills, M; Milner, LS, 1986)
"Colchicine was given to rats in the heterologous phase of passive Heymann nephritis to see whether this drug could reduce proteinuria."3.67Colchicine reduces proteinuria in passive Heymann nephritis. ( Fong, JS; Goodyer, PR; Kaplan, BS; Lotan, D; Mills, M; Milner, LS, 1987)
"Dimethyl sulphoxide (DMSO), 3 g/kg body weight, administered daily by the intraperitoneal route, potentiated the proteinuria and formation of tubular casts in aminonucleoside of puromycin (PA) induced nephrosis in Sprague-Dawley rats."3.67DMSO potentiates aminonucleoside of puromycin nephrosis in rats. ( Allen, J; Conklin, S; Fan, J; Lan, YH; Nguyen, D; Reineck, S; Spear, GS; Wikle, JS, 1987)
"The cellular processes responsible for the proteinuria induced by the aminonucleoside of puromycin (PA) remain inadequately defined."3.67A role for oxygen free radicals in aminonucleoside nephrosis. ( Bonventre, JV; Diamond, JR; Karnovsky, MJ, 1986)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199015 (75.00)18.7374
1990's4 (20.00)18.2507
2000's1 (5.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oteki, T1
Nagase, S1
Yokoyama, H1
Ohya, H1
Akatsuka, T1
Tada, M1
Ueda, A1
Hirayama, A1
Koyama, A1
Rehan, A2
Johnson, KJ2
Wiggins, RC2
Kunkel, RG2
Ward, PA1
Lotan, D3
Kaplan, BS4
Fong, JS3
Goodyer, PR4
de Chadarevian, JP2
Alyabyeva, AP1
Kito, S1
Itoga, E1
Inokawa, M1
Hironaka, M1
Kishida, T1
Shinoda, T1
Ravid, M2
Shapira, J1
Lang, R1
Kedar, I1
Rankin, GO2
Beers, KW1
Nicoll, DW1
Anestis, DK2
Ball, JG1
Valentovic, MA2
Brown, PI2
Hong, SK1
Hawco, NM1
Keizman, IK1
Sohar, E1
van Rijswijk, MH1
Donker, AJ1
Ruinen, L1
Milner, LS4
Wei, SH1
Houser, MT1
Bertolatus, JA1
Klinzman, D1
Bronsema, DA1
Ridnour, L1
Oberley, LW1
Till, GO1
Rahman, MA1
Emancipator, SS1
Sedor, JR1
Thakur, V1
Walker, PD1
Shah, SV1
Mills, M3
Spear, GS1
Nguyen, D1
Conklin, S1
Wikle, JS1
Fan, J1
Lan, YH1
Allen, J1
Reineck, S1
Diamond, JR1
Bonventre, JV1
Karnovsky, MJ1

Other Studies

20 other studies available for dimethyl sulfoxide and Proteinuria

ArticleYear
Normalizing renal reducing ability prevents adriamycin-induced proteinuria.
    Biochemical and biophysical research communications, 2005, Nov-11, Volume: 337, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Doxorubicin; Electron Spin Resonance Spectroscopy; Free Radical Scaveng

2005
Evidence for the role of oxygen radicals in acute nephrotoxic nephritis.
    Laboratory investigation; a journal of technical methods and pathology, 1984, Volume: 51, Issue:4

    Topics: Acute Disease; Animals; Basement Membrane; Catalase; Complement System Proteins; Dimethyl Sulfoxide;

1984
Reduction of protein excretion by dimethyl sulfoxide in rats with passive Heymann nephritis.
    Kidney international, 1984, Volume: 25, Issue:5

    Topics: Animals; Antigen-Antibody Complex; Basement Membrane; Complement C3; Complement Fixation Tests; Dime

1984
Control trials of dimethyl sulfoxide in rheumatoid and collagen diseases.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: Adolescent; Adult; Aged; Amyloidosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Ascorbic Acid; Chi

1983
Studies on biological actions of dimethyl sulfoxide in familial amyloidosis.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: Adult; Aged; Amyloidosis; Chromatography, Gel; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide G

1983
Prolonged dimethylsulphoxide treatment in 13 patients with systemic amyloidosis.
    Annals of the rheumatic diseases, 1982, Volume: 41, Issue:6

    Topics: Adult; Aged; Amyloidosis; Creatinine; Dimethyl Sulfoxide; Female; Humans; Kidney Function Tests; Mal

1982
Effect of dimethyl sulfoxide on N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity.
    Toxicology, 1995, Jun-26, Volume: 100, Issue:1-3

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Biotransformation; Blood Urea Nitrogen; Dimethy

1995
Nephrotoxicity of N-(3-bromophenyl)-2-hydroxysuccinimide: role of halogen groups in the nephrotoxic potential of N-(halophenyl) succinimides.
    Toxicology, 1996, Jun-17, Volume: 110, Issue:1-3

    Topics: Analysis of Variance; Animals; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Fungicides, Ind

1996
Effect of a single dose of dimethyl sulphoxide on renal amyloidosis.
    Lancet (London, England), 1977, Apr-02, Volume: 1, Issue:8014

    Topics: Administration, Oral; Amyloid; Amyloidosis; Animals; Dimethyl Sulfoxide; Humans; Injections, Intrave

1977
Dimethylsulphoxide in amyloidosis.
    Lancet (London, England), 1979, Jan-27, Volume: 1, Issue:8109

    Topics: Amyloid; Amyloidosis; C-Reactive Protein; Circadian Rhythm; Creatinine; Dimethyl Sulfoxide; Humans;

1979
Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea.
    The Journal of laboratory and clinical medicine, 1991, Volume: 118, Issue:5

    Topics: Acetylglucosaminidase; Albuminuria; Animals; Benzoates; Benzoic Acid; Creatine; Dimethyl Sulfoxide;

1991
Evaluation of the role of reactive oxygen species in doxorubicin hydrochloride nephrosis.
    The Journal of laboratory and clinical medicine, 1991, Volume: 118, Issue:5

    Topics: Animals; Catalase; Cells, Cultured; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Doxorubici

1991
Glomerular injury and proteinuria in rats after intrarenal injection of cobra venom factor. Evidence for the role of neutrophil-derived oxygen free radicals.
    The American journal of pathology, 1986, Volume: 123, Issue:1

    Topics: Animals; Catalase; Complement Activation; Deferoxamine; Dimethyl Sulfoxide; Elapid Venoms; Free Radi

1986
Hydroxyl radical scavengers ameliorate proteinuria in rat immune complex glomerulonephritis.
    The Journal of laboratory and clinical medicine, 1988, Volume: 112, Issue:5

    Topics: Animals; Complement C3; Complement C5; Creatinine; Dimethyl Sulfoxide; gamma-Globulins; Glomerulonep

1988
Evidence suggesting a role for hydroxyl radical in puromycin aminonucleoside-induced proteinuria.
    Kidney international, 1988, Volume: 34, Issue:4

    Topics: Animals; Benzoates; Benzoic Acid; Deferoxamine; Dimethyl Sulfoxide; Hydroxides; Hydroxyl Radical; Ma

1988
Interactions of dimethyl sulfoxide and nonsteroidal anti-inflammatory agents in passive Heymann's nephritis.
    The Journal of laboratory and clinical medicine, 1986, Volume: 107, Issue:5

    Topics: Animals; Complement C3; Dimethyl Sulfoxide; Drug Therapy, Combination; Immune Complex Diseases; Indo

1986
Amelioration of murine lupus nephritis by dimethylsulfoxide.
    Clinical immunology and immunopathology, 1987, Volume: 45, Issue:2

    Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; Complement C3; Creatinine; Dimethyl Sulfoxide

1987
Colchicine reduces proteinuria in passive Heymann nephritis.
    Nephron, 1987, Volume: 46, Issue:1

    Topics: Animals; Colchicine; Dimethyl Sulfoxide; Glomerulonephritis; Male; Proteinuria; Rats; Rats, Inbred S

1987
DMSO potentiates aminonucleoside of puromycin nephrosis in rats.
    The Journal of pathology, 1987, Volume: 153, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Drug Synergism; Kidney; Male; Nephrosis, Lipoid; Proteinuria; Puromycin

1987
A role for oxygen free radicals in aminonucleoside nephrosis.
    Kidney international, 1986, Volume: 29, Issue:2

    Topics: Allopurinol; Animals; Catalase; Depression, Chemical; Dimethyl Sulfoxide; Disease Models, Animal; Fr

1986