Page last updated: 2024-10-18

dimethyl sulfoxide and Pain

dimethyl sulfoxide has been researched along with Pain in 76 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
" Patients with a recent diagnosis of interstitial cystitis/painful bladder syndrome (IC/PBS) were randomized 1:1 to treatment with either 6 weekly bladder instillations of DMSO with triamcinolone or BTH."9.69A prospective, randomized trial comparing intravesical dimethyl sulfoxide (DMSO) to bupivacaine, triamcinolone, and heparin (BTH), for newly diagnosed interstitial cystitis/painful bladder syndrome (IC/PBS). ( Chang, C; Chill, HH; Gafni-Kane, A; Goldberg, RP; Moss, NP; Sand, PK, 2023)
"The purpose of this study was to investigate change in bladder capacity as a measure of response to combined intravesical dimethyl sulfoxide (DMSO) and triamcinolone instillations for the treatment of newly diagnosed bladder pain syndrome/interstitial cystitis (BPS/IC)."7.79Measuring the success of combined intravesical dimethyl sulfoxide and triamcinolone for treatment of bladder pain syndrome/interstitial cystitis. ( Botros, SM; Du, H; Gafni-Kane, A; Sand, PK; Sand, RI, 2013)
"The influence of emotional painful stress (EPS) and dimethyl sulfoxide (DMSO) treatment on ceruloplasmin-transferrin (Cp-Tr) antioxidant system and superoxide dismutase-like activity (SODLA) of the rat serum was studied."7.67[Superoxide elimination activity and the transferrin-ceruloplasmin antioxidant system in the blood serum in chronic emotional-pain stress and the administration of dimethyl sulfoxide in rats]. ( Avalian, AKh; Guliaeva, NV; Kozlov, AV; Levshina, IP; Obidin, AB, 1988)
" At least one adverse event was reported in 14."6.84A randomized, open-label, multicenter study of the efficacy and safety of intravesical hyaluronic acid and chondroitin sulfate versus dimethyl sulfoxide in women with bladder pain syndrome/interstitial cystitis. ( Cervigni, M; Ciani, O; Frangione, V; Giammò, A; Ostardo, E; Pappagallo, GL; Porru, D; Sommariva, M; Tarricone, R; Tenaglia, R; Trevisan, S, 2017)
" Patients with a recent diagnosis of interstitial cystitis/painful bladder syndrome (IC/PBS) were randomized 1:1 to treatment with either 6 weekly bladder instillations of DMSO with triamcinolone or BTH."5.69A prospective, randomized trial comparing intravesical dimethyl sulfoxide (DMSO) to bupivacaine, triamcinolone, and heparin (BTH), for newly diagnosed interstitial cystitis/painful bladder syndrome (IC/PBS). ( Chang, C; Chill, HH; Gafni-Kane, A; Goldberg, RP; Moss, NP; Sand, PK, 2023)
"The main therapy for metastatic prostate cancer (MPC) includes androgen manipulation, chemotherapy, and radiotherapy and/or radioisotopes."5.37Dimethyl sulfoxide-sodium bicarbonate infusion for palliative care and pain relief in patients with metastatic prostate cancer. ( Bui, NT; Ha, TV; Hoang, BX; Hoang, C; Le, BT; Pham, CQ; Pham, TD; Shaw, DG; Tran, DM; Tran, HD; Tran, HQ, 2011)
"The objective of the study was to compare the efficacy of dimethyl sulfoxide (DMSO) mixed with lignocaine and eutectic mixture of local anesthetics (EMLA) cream as topically applied surface anesthetics in relieving pain during shock wave lithotripsy (SWL) in a prospective randomized study."5.15Dimethyl sulfoxide with lignocaine versus eutectic mixture of local anesthetics: prospective randomized study to compare the efficacy of cutaneous anesthesia in shock wave lithotripsy. ( Ganesamoni, R; Kumar, S; Mandal, AK; Prasad, S; Singh, SK, 2011)
"The use of 40% DMSO with lidocaine instilled into the rectal vault for 10 minutes avoids any need for injection and is capable of decreasing the discomfort or pain experienced during probe insertion and prostate biopsy comparable to the perianal and periprostatic protocols."5.11Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study. ( Ben-Dor, D; Cytron, S; Dorfman, D; Kesari, D; Kravchick, S; Peled, R, 2005)
"Age, APACHE score at ICU admission, neurological disease, sepsis and duration of mechanical ventilation were all independent risk factors for the development of delirium in ICU patients."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"The purpose of this study was to investigate change in bladder capacity as a measure of response to combined intravesical dimethyl sulfoxide (DMSO) and triamcinolone instillations for the treatment of newly diagnosed bladder pain syndrome/interstitial cystitis (BPS/IC)."3.79Measuring the success of combined intravesical dimethyl sulfoxide and triamcinolone for treatment of bladder pain syndrome/interstitial cystitis. ( Botros, SM; Du, H; Gafni-Kane, A; Sand, PK; Sand, RI, 2013)
"We investigated whether capsaicin induces itching in skin with existing inflammation."3.77Capsaicin induces reflex scratching in inflamed skin. ( Ji, W; Liang, J; Xiao, G, 2011)
"The authors developed and evaluated a transdermal gel formulation of ketorolac tromethamine (ketorolac) for the treatment of nociceptive somatic pain."3.75Ketorolac tromethamine transdermal gel: development, in vitro and in vivo evaluation. ( Bommagani, M; Dubey, R; Karnati, HR; Menon, VC; Mullangi, R; Thammera, RK; Venkateswarlu, V, 2009)
" We then demonstrated that this procedure allows the detection of both thermal allodynia and hyperalgesia after peripheral pain sensitization with capsaicin in mice and in rats."3.75Differentiating thermal allodynia and hyperalgesia using dynamic hot and cold plate in rodents. ( Barrot, M; Charlet, A; Freund-Mercier, MJ; Poisbeau, P; Yalcin, I, 2009)
"Spinal cord microglial toll-like receptor 4 (TLR4) has been implicated in enhancing neuropathic pain and opposing morphine analgesia."3.75Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. ( Crysdale, NY; Harrison, JA; Hutchinson, MR; Kearney, JJ; Lewis, MT; Loram, LC; Maier, SF; Ramos, KM; Rice, KC; Sholar, PW; Watkins, LR; Wieseler, J; Zhang, Y, 2009)
"5%), jaw pain in 1 patient (3."3.74Results and complications of transarterial embolization of intracranial dural arteriovenous fistulas using Onyx-18. ( Jiang, C; Li, Y; Lv, X; Wu, Z, 2008)
"The influence of emotional painful stress (EPS) and dimethyl sulfoxide (DMSO) treatment on ceruloplasmin-transferrin (Cp-Tr) antioxidant system and superoxide dismutase-like activity (SODLA) of the rat serum was studied."3.67[Superoxide elimination activity and the transferrin-ceruloplasmin antioxidant system in the blood serum in chronic emotional-pain stress and the administration of dimethyl sulfoxide in rats]. ( Avalian, AKh; Guliaeva, NV; Kozlov, AV; Levshina, IP; Obidin, AB, 1988)
" At least one adverse event was reported in 14."2.84A randomized, open-label, multicenter study of the efficacy and safety of intravesical hyaluronic acid and chondroitin sulfate versus dimethyl sulfoxide in women with bladder pain syndrome/interstitial cystitis. ( Cervigni, M; Ciani, O; Frangione, V; Giammò, A; Ostardo, E; Pappagallo, GL; Porru, D; Sommariva, M; Tarricone, R; Tenaglia, R; Trevisan, S, 2017)
"125 grams 3 times daily for 12 weeks and the other received a placebo in the same dosing frequency."2.76Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. ( Agar, G; Beer, Y; Debbi, EM; Debi, R; Elbaz, A; Fichman, G; Halperin, N; Kardosh, R; Ziv, YB, 2011)
"Various anesthetic approaches have been used to make cystoscopy more tolerable for patients."2.73Patient tolerance during cystoscopy: a randomized study comparing lidocaine hydrochloride gel and dimethyl sulfoxide with lidocaine. ( Bedir, S; Demir, E; Erken, U; Kilciler, M, 2008)
"To share our experiences in the treatment of interstitial cystitis, additionally, to comment on the therapeutic response of treatment used."2.47[Experience in the treatment of interstitial cystitis: review of 17 cases]. ( Flores-Carreras, O; González-Ruiz, MI; Martínez-Espinoza, CJ, 2011)
"Interstitial cystitis/painful bladder syndrome is a chronic disease characterized by pain, frequency, urgency, and nocturia and diagnosed primarily in women."2.44Interstitial cystitis/painful bladder syndrome. ( Warren, JW, 2007)
"The management of bladder pain syndrome (BPS) in our center is standardized although there is no real consensus and recommendations."1.72[Bladder pain syndrome: Long-term results (15 years) of a single-center experience]. ( De Cian, M; Saussine, C; Tricard, T, 2022)
"The main therapy for metastatic prostate cancer (MPC) includes androgen manipulation, chemotherapy, and radiotherapy and/or radioisotopes."1.37Dimethyl sulfoxide-sodium bicarbonate infusion for palliative care and pain relief in patients with metastatic prostate cancer. ( Bui, NT; Ha, TV; Hoang, BX; Hoang, C; Le, BT; Pham, CQ; Pham, TD; Shaw, DG; Tran, DM; Tran, HD; Tran, HQ, 2011)
"The mean interval from diagnosis of interstitial cystitis to the first day of the last menstrual cycle preceding all pregnancies beyond 28 weeks was 19."1.32Pregnancy outcomes following the diagnosis of interstitial cystitis. ( Onwude, JL; Selo-Ojeme, DO, 2003)
"Rats treated with nifedipine alone had an increase in tail-flick latency of 122%, as measured by the area under the curve, compared to rats treated with DMSO alone."1.29Ondansetron blocks nifedipine-induced analgesia in rats. ( Hunt, TE; Wu, W; Zbuzek, VK, 1996)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199022 (28.95)18.7374
1990's11 (14.47)18.2507
2000's20 (26.32)29.6817
2010's15 (19.74)24.3611
2020's8 (10.53)2.80

Authors

AuthorsStudies
Gusso, D1
Cruz, FF1
Fritsch, PM1
Gobbo, MO1
Morrone, FB1
Bonan, CD1
De Cian, M1
Tricard, T1
Saussine, C1
Abdi Dezfouli, R1
Ghanbari Merdasi, P1
Rashvand, M1
Mousavi, Z1
Haghparast, A2
Moss, NP1
Chill, HH1
Sand, PK2
Chang, C1
Goldberg, RP1
Gafni-Kane, A2
Toguchi, A1
Noguchi, N1
Kanno, T1
Yamada, A1
Zakeri, M1
Soltanizadeh, S1
Karimi-Haghighi, S1
Olds, J1
Yousif, M1
Abidakun, O1
Cannon, A1
Wein, AJ1
Honarmand, AR1
Ansari, SA1
Soltanolkotabi, M1
Tomita, T1
Alden, TD1
Hurley, MC1
Schoeneman, SE1
Shaibani, A1
Takeda, K1
Pokorski, M1
Okada, Y1
Cervigni, M1
Sommariva, M1
Tenaglia, R1
Porru, D1
Ostardo, E1
Giammò, A1
Trevisan, S1
Frangione, V1
Ciani, O1
Tarricone, R1
Pappagallo, GL1
Goh, CF1
Craig, DQ1
Hadgraft, J1
Lane, ME1
Rawls, WF1
Cox, L1
Rovner, ES1
Colucci, M1
Maione, F1
Bonito, MC1
Piscopo, A1
Di Giannuario, A1
Pieretti, S1
Xie, Q1
Shi, R1
Xu, G1
Cheng, L1
Shao, L1
Rao, J1
Lv, X1
Jiang, C1
Li, Y1
Wu, Z1
Sea, J1
Teichman, JM1
Dubey, R1
Bommagani, M1
Venkateswarlu, V1
Mullangi, R1
Karnati, HR1
Thammera, RK1
Menon, VC1
Yalcin, I1
Charlet, A1
Freund-Mercier, MJ1
Barrot, M1
Poisbeau, P1
Bastos, LC1
Tonussi, CR1
Hutchinson, MR1
Ramos, KM1
Loram, LC1
Wieseler, J1
Sholar, PW1
Kearney, JJ1
Lewis, MT1
Crysdale, NY1
Zhang, Y1
Harrison, JA1
Maier, SF1
Rice, KC1
Watkins, LR1
Moen, MD1
Mohammadi-Samani, S1
Jamshidzadeh, A1
Montaseri, H1
Rangbar-Zahedani, M1
Kianrad, R1
Kumar, S2
Ganesamoni, R1
Mandal, AK1
Prasad, S1
Singh, SK1
Debbi, EM1
Agar, G1
Fichman, G1
Ziv, YB1
Kardosh, R1
Halperin, N1
Elbaz, A1
Beer, Y1
Debi, R1
Liang, J1
Xiao, G1
Ji, W1
Hoang, BX1
Le, BT1
Tran, HD1
Hoang, C1
Tran, HQ1
Tran, DM1
Pham, CQ1
Pham, TD1
Ha, TV1
Bui, NT1
Shaw, DG1
Flores-Carreras, O1
Martínez-Espinoza, CJ1
González-Ruiz, MI1
Joksimovic, N1
Spasovski, G1
Joksimovic, V1
Andreevski, V1
Zuccari, C1
Omini, CF1
Botros, SM1
Du, H1
Sand, RI1
ROSENBAUM, WM1
ROSENBAUM, EE1
JACOB, SW1
Onwude, JL1
Selo-Ojeme, DO1
Bolin, DJ1
Tincello, DG1
Walker, AC1
Kravchick, S1
Peled, R1
Ben-Dor, D1
Dorfman, D1
Kesari, D1
Cytron, S1
Rössberger, J1
Fall, M1
Peeker, R1
Kim, LS1
Axelrod, LJ1
Howard, P1
Buratovich, N1
Waters, RF1
Zakaria, ZA2
Gopalan, HK2
Zainal, H1
Mohd Pojan, NH1
Morsid, NA1
Aris, A1
Sulaiman, MR2
Abdul Ghani, ZD1
Raden Mohd Nor, RN1
Abdullah, FC1
Warren, JW1
Demir, E1
Kilciler, M1
Bedir, S1
Erken, U1
Burton, WJ1
Gould, PW1
Hursthouse, MW1
Sears, PJ1
Larnder, DA1
Stringer, HC1
Turnbull, BC1
Wong, CH1
Dey, P1
Yarmush, J1
Wu, WH1
Zbuzek, VK2
Ji, H1
Zhang, R1
Hu, X1
Lai, L1
Xu, X1
Hunt, TE1
Wu, W1
Kubota, K1
Fujibayashi, K1
Saito, K1
Mason, DJ1
Lowe, J1
Welch, SP1
Bos, AM1
van der Graaf, WT1
Willemse, PH1
Dubinsky, MB1
Skager, AA1
Shchekoldin, PI1
Oranskiĭ, IE1
Obrazova, RG1
Glatz, PC1
Murphy, LB1
Preston, AP1
Panchenko, EN1
Yaksh, TL1
Jang, JD1
Nishiuchi, Y1
Braun, KP1
Ro, SG1
Goodman, M1
Salim, AS1
Ramahi, AJ1
Richardson, DA1
Guliaeva, NV1
Levshina, IP1
Obidin, AB1
Avalian, AKh1
Kozlov, AV1
Trice, JM1
Pinals, RS1
Subotnick, SI1
Persky, L1
Steeart, BH1
Simpson, JR1
David, NA1
Vuopala, U1
Vesterinen, E1
Kaipainen, WJ1
Brown, JH1
Arno, IC1
Wapner, PM1
Brownstein, IE1
Penrod, DS1
Bacharach, B1
Templeton, JY1
Lockie, LM1
Norcross, BM1
von der Hardt, H1
Röper, HJ1
Sudhof, H1
Matsumoto, J1
Blumenthal, LS1
Fuchs, M1
Young, HF2
Becker, DP2
Jane, JA2
Nulsen, FE2
Häusler, G1
Jahn, U1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Investigative, Randomized, Open, Pilot Study to Assess the Tolerability, Safety and Efficacy of HAcid/CS Intravesical Instillations Plus an Oral Combination of Curcumin,Quercetin, HA and CS in Prevention of Radiation Induced Cystitis[NCT03493997]Phase 2100 participants (Actual)Interventional2017-04-04Completed
A Randomized Trial of Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome[NCT04401176]Phase 258 participants (Actual)Interventional2020-09-15Completed
Efficacy of PENNSAID® for Pain Management in the Emergency Department[NCT01350622]0 participants (Actual)Interventional2011-12-31Withdrawn (stopped due to Study never initiated)
[NCT01188213]0 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for dimethyl sulfoxide and Pain

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Dimethyl sulfoxide (DMSO) as intravesical therapy for interstitial cystitis/bladder pain syndrome: A review.
    Neurourology and urodynamics, 2017, Volume: 36, Issue:7

    Topics: Administration, Intravesical; Analgesics; Cystitis, Interstitial; Dimethyl Sulfoxide; Humans; Pain;

2017
Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment.
    Drugs, 2009, Volume: 69, Issue:3

    Topics: Administration, Intravesical; Amitriptyline; Child; Cimetidine; Cystitis, Interstitial; Diet Therapy

2009
[Experience in the treatment of interstitial cystitis: review of 17 cases].
    Ginecologia y obstetricia de Mexico, 2011, Volume: 79, Issue:3

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Cystitis, Interstitial; Dexamethasone;

2011
Transdermal approaches to pain in sports injury management.
    Current sports medicine reports, 2003, Volume: 2, Issue:6

    Topics: Administration, Cutaneous; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Athlet

2003
Interstitial cystitis/painful bladder syndrome.
    Urologic nursing, 2007, Volume: 27, Issue:3

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; C

2007
Dimethyl sulfoxide: a review of its use in the rheumatic disorders.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:1

    Topics: Amyloidosis; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cell Division; Chemical Phenomena; Che

1985
The pharmacology of dimethyl sulfoxide.
    Annual review of pharmacology, 1972, Volume: 12

    Topics: Abnormalities, Drug-Induced; Absorption; Analgesics; Animals; Anti-Inflammatory Agents; Anura; Biolo

1972

Trials

18 trials available for dimethyl sulfoxide and Pain

ArticleYear
A prospective, randomized trial comparing intravesical dimethyl sulfoxide (DMSO) to bupivacaine, triamcinolone, and heparin (BTH), for newly diagnosed interstitial cystitis/painful bladder syndrome (IC/PBS).
    Neurourology and urodynamics, 2023, Volume: 42, Issue:3

    Topics: Administration, Intravesical; Bupivacaine; Cystitis, Interstitial; Dimethyl Sulfoxide; Female; Hepar

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Nutrients, 2023, Jun-30, Volume: 15, Issue:13

    Topics: Dimethyl Sulfoxide; Double-Blind Method; Humans; Knee Joint; Osteoarthritis, Knee; Pain; Quality of

2023
A randomized, open-label, multicenter study of the efficacy and safety of intravesical hyaluronic acid and chondroitin sulfate versus dimethyl sulfoxide in women with bladder pain syndrome/interstitial cystitis.
    Neurourology and urodynamics, 2017, Volume: 36, Issue:4

    Topics: Administration, Intravesical; Adolescent; Adult; Aged; Aged, 80 and over; Chondroitin Sulfates; Cost

2017
Effects of AR7 Joint Complex on arthralgia for patients with osteoarthritis: results of a three-month study in Shanghai, China.
    Nutrition journal, 2008, Oct-27, Volume: 7

    Topics: Anti-Inflammatory Agents; Arthralgia; Arthrography; China; Collagen Type II; Dietary Supplements; Di

2008
Dimethyl sulfoxide with lignocaine versus eutectic mixture of local anesthetics: prospective randomized study to compare the efficacy of cutaneous anesthesia in shock wave lithotripsy.
    Urological research, 2011, Volume: 39, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthetics, Local; Dimethyl Sulfoxide; Drug The

2011
Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study.
    BMC complementary and alternative medicine, 2011, Jun-27, Volume: 11

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents;

2011
Efficacy and tolerability of hyaluronic acid, tea tree oil and methyl-sulfonyl-methane in a new gel medical device for treatment of haemorrhoids in a double-blind, placebo-controlled clinical trial.
    Updates in surgery, 2012, Volume: 64, Issue:3

    Topics: Administration, Topical; Adolescent; Anal Canal; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Doubl

2012
Comparison of different local anesthesia techniques during TRUS-guided biopsies: a prospective pilot study.
    Urology, 2005, Volume: 65, Issue:1

    Topics: Adenocarcinoma; Adjuvants, Anesthesia; Administration, Rectal; Aged; Anesthesia, Local; Anesthetics,

2005
Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial.
    Osteoarthritis and cartilage, 2006, Volume: 14, Issue:3

    Topics: Adult; Aged; Analgesics; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Drug Administ

2006
Patient tolerance during cystoscopy: a randomized study comparing lidocaine hydrochloride gel and dimethyl sulfoxide with lidocaine.
    Journal of endourology, 2008, Volume: 22, Issue:5

    Topics: Adult; Aged; Ambulatory Care; Anesthetics, Local; Cystoscopy; Dimethyl Sulfoxide; Drug Combinations;

2008
A multicentre trial of Zostrum (5 percent idoxuridine in dimethyl sulphoxide) in herpes zoster.
    The New Zealand medical journal, 1981, Nov-25, Volume: 94, Issue:696

    Topics: Administration, Topical; Analgesics; Clinical Trials as Topic; Dimethyl Sulfoxide; Drug Eruptions; H

1981
Scavengers of oxygen-derived free radicals. A new approach to the problem of pancreatitis-induced abdominal pain.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1991, Volume: 4, Issue:4

    Topics: Adult; Allopurinol; Dimethyl Sulfoxide; Drug Therapy, Combination; Humans; Male; Middle Aged; Pain;

1991
The analgetic action of dimethyl sulfoxide (DMSO) ointment in arthrosis. A double blind study.
    Acta rheumatologica Scandinavica, 1971, Volume: 17, Issue:1

    Topics: Arthritis; Clinical Trials as Topic; Dimethyl Sulfoxide; Humans; Middle Aged; Ointments; Pain; Place

1971
DMSO--its efficacy in acute musculoskeletal problems as evaluated by a "double blind" study.
    Industrial medicine & surgery, 1966, Volume: 35, Issue:9

    Topics: Dimethyl Sulfoxide; Humans; Joint Diseases; Muscular Diseases; Ointments; Pain; Placebos

1966
[Centrally caused or general analgetic effect of locally administered dimethyl sulfoxide (DMSO)].
    Die Medizinische Welt, 1969, Mar-15, Volume: 11

    Topics: Adult; Aged; Analgesics; Dimethyl Sulfoxide; Dosage Forms; Humans; Middle Aged; Pain; Rheumatic Dise

1969
Clinical trials of dimethyl sulfoxide in rheumatoid arthritis patients in Japan.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dimethyl Sulfoxide; Edema; Female; Fever; Humans; I

1967
The clinical use of dimethyl sulfoxide on various headaches, musculoskeletal, and other general medical disorders.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Bone Diseases; Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Headache; Humans; Male; Muscula

1967

Other Studies

51 other studies available for dimethyl sulfoxide and Pain

ArticleYear
Pannexin channel 1, P2×7 receptors, and Dimethyl Sulfoxide mediate pain responses in zebrafish.
    Behavioural brain research, 2022, 04-09, Volume: 423

    Topics: Analgesics; Animals; Behavior, Animal; Connexins; Dimethyl Sulfoxide; Disease Models, Animal; Larva;

2022
[Bladder pain syndrome: Long-term results (15 years) of a single-center experience].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2022, Volume: 32, Issue:10

    Topics: Administration, Intravesical; Cystitis, Interstitial; Dimethyl Sulfoxide; Female; Humans; Male; Pain

2022
The modulatory role of dopamine receptors within the hippocampal cornu ammonis area 1 in stress-induced analgesia in an animal model of persistent inflammatory pain.
    Behavioural pharmacology, 2022, 10-01, Volume: 33, Issue:7

    Topics: Analgesia; Animals; Benzazepines; Dimethyl Sulfoxide; Disease Models, Animal; Dopamine Antagonists;

2022
Modulatory role of hippocampal dopamine receptors in antinociceptive responses induced by chemical stimulation of the lateral hypothalamus in an animal model of persistent inflammatory pain.
    Brain research bulletin, 2020, Volume: 162

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; CA1 Region, Hippocampal; Dimethyl Sulfoxide; Disease

2020
Case of recurrent cerebral haemorrhage in an older adult man who uses dimethylsulfoxide (DMSO) for self-management of low mood and pain.
    BMJ case reports, 2021, Feb-04, Volume: 14, Issue:2

    Topics: Aged; Cerebral Hemorrhage; Depression; Dimethyl Sulfoxide; Drug Misuse; Humans; Male; Pain; Recurren

2021
Re: Long-Term Outcomes of Intravesical Dimethyl Sulfoxide/Heparin/Hydrocortisone Therapy for Interstitial Cystitis/Bladder Pain Syndrome.
    The Journal of urology, 2018, Volume: 199, Issue:4

    Topics: Cystitis, Interstitial; Dimethyl Sulfoxide; Heparin; Humans; Hydrocortisone; Pain

2018
Use of Onyx for endovascular embolization of pediatric spinal perimedullary (Type IV) fistula: case report.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Adolescent; Angiography, Digital Subtraction; Arteriovenous Fistula; Child; Dimethyl Sulfoxide; Embo

2013
Thermal Sensitivity and Dimethyl Sulfoxide (DMSO).
    Advances in experimental medicine and biology, 2016, Volume: 921

    Topics: Animals; Cryoprotective Agents; Dimethyl Sulfoxide; Hot Temperature; Male; Mice; Mice, Inbred C57BL;

2016
The application of ATR-FTIR spectroscopy and multivariate data analysis to study drug crystallisation in the stratum corneum.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 111

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cluster Anal

2017
New insights of dimethyl sulphoxide effects (DMSO) on experimental in vivo models of nociception and inflammation.
    Pharmacological research, 2008, Volume: 57, Issue:6

    Topics: Administration, Oral; Animals; Anti-Infective Agents, Local; Dimethyl Sulfoxide; Edema; Formaldehyde

2008
Results and complications of transarterial embolization of intracranial dural arteriovenous fistulas using Onyx-18.
    Journal of neurosurgery, 2008, Volume: 109, Issue:6

    Topics: Adult; Arteriovenous Fistula; Cerebral Angiography; Dimethyl Sulfoxide; Embolization, Therapeutic; F

2008
Ketorolac tromethamine transdermal gel: development, in vitro and in vivo evaluation.
    Journal of pain & palliative care pharmacotherapy, 2009, Volume: 23, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; C

2009
Differentiating thermal allodynia and hyperalgesia using dynamic hot and cold plate in rodents.
    The journal of pain, 2009, Volume: 10, Issue:7

    Topics: Animals; Behavior, Animal; Capsaicin; Carrageenan; Cold Temperature; Dimethyl Sulfoxide; Escape Reac

2009
PGE(2)-induced lasting nociception to heat: evidences for a selective involvement of A-delta fibres in the hyperpathic component of hyperalgesia.
    European journal of pain (London, England), 2010, Volume: 14, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Dimethyl Sulfoxide; Dinoprostone; Hot T

2010
Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats.
    Neuroscience, 2009, Dec-29, Volume: 164, Issue:4

    Topics: Analgesics, Opioid; Animals; Benzoquinones; Constriction, Pathologic; Dimethyl Sulfoxide; HSP90 Heat

2009
Topical diclofenac solution.
    Drugs, 2009, Volume: 69, Issue:18

    Topics: Activities of Daily Living; Administration, Cutaneous; Administration, Oral; Anti-Inflammatory Agent

2009
The effects of some permeability enhancers on the percutaneous absorption of lidocaine.
    Pakistan journal of pharmaceutical sciences, 2010, Volume: 23, Issue:1

    Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Cyclohexane Monoterpenes; Cyclohexanols; Cyc

2010
Capsaicin induces reflex scratching in inflamed skin.
    Pharmacology, 2011, Volume: 88, Issue:1-2

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Capsaici

2011
Dimethyl sulfoxide-sodium bicarbonate infusion for palliative care and pain relief in patients with metastatic prostate cancer.
    Journal of pain & palliative care pharmacotherapy, 2011, Volume: 25, Issue:4

    Topics: Adenocarcinoma; Aged; Dimethyl Sulfoxide; Drug Combinations; Humans; Male; Middle Aged; Neoplasm Met

2011
Measuring the success of combined intravesical dimethyl sulfoxide and triamcinolone for treatment of bladder pain syndrome/interstitial cystitis.
    International urogynecology journal, 2013, Volume: 24, Issue:2

    Topics: Administration, Intravesical; Adult; Anti-Inflammatory Agents; Cystitis, Interstitial; Dimethyl Sulf

2013
THE USE OF DIMETHYLSULFOXIDE (DMSO) FOR THE TREATMENT OF INTRACTABLE PAIN IN SURGICAL PATIENTS.
    Surgery, 1965, Volume: 58

    Topics: Amputation Stumps; Dimethyl Sulfoxide; Drug Therapy; Humans; Pain; Pain, Intractable; Patients; Phan

1965
Pregnancy outcomes following the diagnosis of interstitial cystitis.
    Gynecologic and obstetric investigation, 2003, Volume: 56, Issue:3

    Topics: Adult; Cystitis, Interstitial; Dimethyl Sulfoxide; Female; Fertilization; Humans; Pain; Pregnancy; P

2003
Interstitial cystitis in the UK: results of a questionnaire survey of members of the Interstitial Cystitis Support Group.
    European journal of obstetrics, gynecology, and reproductive biology, 2005, Jan-10, Volume: 118, Issue:1

    Topics: Anticonvulsants; Cimetidine; Cystitis, Interstitial; Depression; Dimethyl Sulfoxide; Female; Histami

2005
Critical appraisal of dimethyl sulfoxide treatment for interstitial cystitis: discomfort, side-effects and treatment outcome.
    Scandinavian journal of urology and nephrology, 2005, Volume: 39, Issue:1

    Topics: Administration, Intravesical; Cystitis, Interstitial; Dimethyl Sulfoxide; Drug Administration Schedu

2005
Antinociceptive, anti-inflammatory and antipyretic effects of Solanum nigrum chloroform extract in animal models.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2006, Volume: 126, Issue:11

    Topics: Animals; Chloroform; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; E

2006
Antinociceptive and anti-inflammatory activities of Dicranopteris linearis leaves chloroform extract in experimental animals.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2006, Volume: 126, Issue:11

    Topics: Animals; Chloroform; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; E

2006
Nifedipine-induced analgesia after epidural injection in rats.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:2

    Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dimethyl Sulfoxide; Hot Temperature; Male; Nife

1994
Synthesis, conformation and opioid activity of deltorphins.
    Biochemical and biophysical research communications, 1995, Feb-06, Volume: 207, Issue:1

    Topics: Analgesics; Animals; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Indicators and Reagen

1995
Ondansetron blocks nifedipine-induced analgesia in rats.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:3

    Topics: Analgesia; Analgesics; Animals; Dimethyl Sulfoxide; Injections, Intraperitoneal; Male; Nifedipine; O

1996
Enhancing effect of dimethyl sulfoxide on nociceptive transmission in isolated spinal cord of newborn rat.
    European journal of pharmacology, 1998, Jun-19, Volume: 351, Issue:2

    Topics: Animals; Animals, Newborn; Capsaicin; Cholinesterases; Dimethyl Sulfoxide; Electric Stimulation; Exc

1998
Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception.
    European journal of pharmacology, 1999, Aug-13, Volume: 378, Issue:3

    Topics: Analgesics; Animals; Cannabinoids; Cyclohexanols; Dimethyl Sulfoxide; Dronabinol; Dynorphins; Inject

1999
Pain. MSM: does it work?
    Harvard health letter, 2000, Volume: 25, Issue:10

    Topics: Analgesics; Dimethyl Sulfoxide; Humans; Pain; Sulfones

2000
A new conservative approach to extravasation of anthracyclines with dimethylsulfoxide and dexrazoxane.
    Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; C

2001
Experience in the use of dimethyl sulfoxide in the diseases of the supporting motor apparatus and general suppurative surgery.
    Annals of the New York Academy of Sciences, 1975, Jan-27, Volume: 243

    Topics: Anti-Infective Agents; Dimethyl Sulfoxide; Drug Combinations; Erysipelas; Heparin; Humans; Pain; Rhe

1975
Editorial: Pain relief in minor musculoskeletal disorders.
    British medical journal, 1976, May-29, Volume: 1, Issue:6021

    Topics: Aspirin; Athletic Injuries; Dimethyl Sulfoxide; Humans; Indomethacin; Pain; Sprains and Strains

1976
[Acetylsalicylic acid ultraphonophoresis in the treatment of the pain syndrome in patients with lumbar osteochondrosis].
    Likars'ka sprava, 1992, Issue:2

    Topics: Adult; Animals; Aspirin; Dimethyl Sulfoxide; Drug Evaluation; Drug Evaluation, Preclinical; Drug Sta

1992
Analgesic therapy of beak-trimmed chickens.
    Australian veterinary journal, 1992, Volume: 69, Issue:1

    Topics: Administration, Topical; Analgesics; Animals; Beak; Behavior, Animal; Bupivacaine; Chickens; Dimethy

1992
[A method of objective evaluation of pain].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990, Volume: 90, Issue:4

    Topics: Administration, Cutaneous; Adult; Dimethyl Sulfoxide; Humans; Iodine; Male; Middle Aged; Migraine Di

1990
The utility of 2-hydroxypropyl-beta-cyclodextrin as a vehicle for the intracerebral and intrathecal administration of drugs.
    Life sciences, 1991, Volume: 48, Issue:7

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; alpha-Cyclodextrins; Analgesia; Animals; beta-Cyclodextrins; Calc

1991
A practical approach to the painful bladder syndrome.
    The Journal of reproductive medicine, 1990, Volume: 35, Issue:8

    Topics: Administration, Intravesical; Adult; Aged; Clinical Protocols; Dilatation; Dimethyl Sulfoxide; Exerc

1990
[Superoxide elimination activity and the transferrin-ceruloplasmin antioxidant system in the blood serum in chronic emotional-pain stress and the administration of dimethyl sulfoxide in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 106, Issue:8

    Topics: Animals; Ceruloplasmin; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Male; Pain;

1988
Dimethyl sulfoxide dehydration of the foot. A case history.
    Journal of the American Podiatric Medical Association, 1985, Volume: 75, Issue:5

    Topics: Dehydration; Dimethyl Sulfoxide; Erythema; Female; Humans; Middle Aged; Occlusive Dressings; Pain; S

1985
The use of dimethyl sulfoxide in the treatment of genitourinary disorders.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Adult; Cystitis; Dimethyl Sulfoxide; Epididymitis; Female; Genital Diseases, Male; Herpesviridae Inf

1967
Herpes simplex and zoster.
    British medical journal, 1973, Mar-31, Volume: 1, Issue:5856

    Topics: Adrenocorticotropic Hormone; Aged; Dimethyl Sulfoxide; Herpes Simplex; Herpes Zoster; Humans; Pain

1973
Letter: Idoxuridine in herpes zoster.
    British medical journal, 1974, Aug-24, Volume: 3, Issue:5929

    Topics: Administration, Topical; Aged; Child; Dimethyl Sulfoxide; Drug Hypersensitivity; Herpes Zoster; Huma

1974
Experiences with DMSO in relief of postpartum episiotomy pain.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Adult; Dimethyl Sulfoxide; Episiotomy; Female; Humans; Inflammation; Pain; Postoperative Care; Pregn

1967
Dimethyl sulfoxide for incisional pain after thoracotomy: preliminary report.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Analgesics; Dimethyl Sulfoxide; Humans; Pain; Postoperative Care; Thoracic Diseases; Thoracic Surger

1967
A clinical study on the effects of dimethyl sulfoxide in 103 patients with acute and chronic musculoskeletal injuries and inflammations.
    Annals of the New York Academy of Sciences, 1967, Mar-15, Volume: 141, Issue:1

    Topics: Bone Diseases; Bursitis; Diabetic Neuropathies; Dimethyl Sulfoxide; Humans; Joint Diseases; Muscular

1967
Mechanism of action of dimethyl sulphoxide.
    Surgical forum, 1968, Volume: 19

    Topics: Animals; Cats; Dimethyl Sulfoxide; Neural Conduction; Pain; Radial Nerve

1968
Physiological effects of dimethyl sulfoxide on peripheral nerves: possible role in pain relief.
    Experimental neurology, 1969, Volume: 24, Issue:2

    Topics: Animals; Axons; Cats; Dimethyl Sulfoxide; Fibroblasts; Nerve Fibers, Myelinated; Neural Conduction;

1969
[Studies on the pharmacology of dimethyl sulfoxide (DMSO)].
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 159, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Dimethyl Sulfoxide; Guinea Pigs; Heart; In Vitro

1966