Page last updated: 2024-10-18

dimethyl sulfoxide and Osteosarcoma

dimethyl sulfoxide has been researched along with Osteosarcoma in 11 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Current treatment of high-grade osteosarcoma consists of preoperative chemotherapy, typically using some combination of doxorubicin, cisplatin, ifosfamide, and/or high-dose methotrexate followed by surgical resection."7.91Long-term Outcome After Doxorubicin and Ifosfamide Overdose in a Patient With Osteosarcoma and BARD1 Mutation. ( Savani, M; Skubitz, KM, 2019)
"To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation."7.72Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Current treatment of high-grade osteosarcoma consists of preoperative chemotherapy, typically using some combination of doxorubicin, cisplatin, ifosfamide, and/or high-dose methotrexate followed by surgical resection."3.91Long-term Outcome After Doxorubicin and Ifosfamide Overdose in a Patient With Osteosarcoma and BARD1 Mutation. ( Savani, M; Skubitz, KM, 2019)
" Human osteosarcoma MG63 cells were encapsulated in sodium alginate fiber constructs with wetspinning method and exposed to different formulations of cryopreservation media, containing dimethyl sulfoxide (DMSO), glycerol, and trehalose."3.88Effect of Cryopreservation on Cell-Laden Hydrogels: Comparison of Different Cryoprotectants. ( Bonani, W; Cagol, N; Maniglio, D; Migliaresi, C; Motta, A, 2018)
"To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation."3.72Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004)
" Treatment of human melanoma cells with recombinant fibroblast interferon (IFN-beta) and the protein kinase C activator mezerein (MEZ) results in an irreversible loss in growth potential, suppression of tumorigenic properties and induction of terminal cell differentiation."3.71Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. ( Alexandre, D; Chada, S; Chen, Y; Christiansen, KA; Fisher, PB; Goldstein, NI; Gopalkrishnan, RV; Huang, EY; Huberman, E; Jiang, H; Kang, D; Lebedeva, IV; Leszczyniecka, M; Lin, JJ; Madireddi, MT; Mei, MX; Mhashilkar, AB; Pestka, S; Sivo, F; Su, Z; Vozhilla, N, 2001)
"The concanavalin A-induced agglutination of cultivated cells of human osteosarcoma Sa-4 was studied in the process of their reversion caused by high polar compounds, dimethylsulphoxide (DMSO) and dimethylformamide (DMFA)."3.67[Changes in lectin-induced agglutination of human tumor cells during the process of their reversion]. ( Viadro, MM, 1985)
"A human osteosarcoma clonal cell line (TE-85, clone F-5) was treated in vitro with various levels of 7,12-dimethylbenz[a]anthracene or dimethyl sulfoxide (control)."3.65Transformation of human osteosarcoma cells by a chemical carcinogen. ( Arnstein, P; Huebner, RJ; Kim, CM; Nelson Ress, WA; Rhim, JS; Weisburger, EK, 1975)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Cagol, N1
Bonani, W1
Maniglio, D1
Migliaresi, C1
Motta, A1
Savani, M1
Skubitz, KM1
Menendez, D1
Nguyen, TA1
Freudenberg, JM1
Mathew, VJ1
Anderson, CW1
Jothi, R1
Resnick, MA1
Farese, JP1
Fox, LE1
Detrisac, CJ1
Van Gilder, JM1
Roberts, SL1
Baldwin, JM1
Viadro, MM2
Tikhomirova, EE1
Timofeevskaia, EA1
Dernell, WS1
Straw, RC1
Withrow, SJ1
Powers, BE1
Fujita, SM1
Yewey, GS1
Joseph, KF1
Dunn, RL1
Whitman, SL1
Southard, GL1
Huang, EY1
Madireddi, MT1
Gopalkrishnan, RV1
Leszczyniecka, M1
Su, Z1
Lebedeva, IV1
Kang, D1
Jiang, H1
Lin, JJ1
Alexandre, D1
Chen, Y1
Vozhilla, N1
Mei, MX1
Christiansen, KA1
Sivo, F1
Goldstein, NI1
Mhashilkar, AB1
Chada, S1
Huberman, E1
Pestka, S1
Fisher, PB1
Rhim, JS1
Kim, CM1
Arnstein, P1
Huebner, RJ1
Weisburger, EK1
Nelson Ress, WA1
Mizrahi, A1
Moore, GE1

Reviews

1 review available for dimethyl sulfoxide and Osteosarcoma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Trials

1 trial available for dimethyl sulfoxide and Osteosarcoma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

10 other studies available for dimethyl sulfoxide and Osteosarcoma

ArticleYear
Effect of Cryopreservation on Cell-Laden Hydrogels: Comparison of Different Cryoprotectants.
    Tissue engineering. Part C, Methods, 2018, Volume: 24, Issue:1

    Topics: Alginates; Apoptosis; Bone Neoplasms; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; G

2018
Long-term Outcome After Doxorubicin and Ifosfamide Overdose in a Patient With Osteosarcoma and BARD1 Mutation.
    Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cardiotoxicity; Dimethyl Sulf

2019
Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells.
    Nucleic acids research, 2013, Volume: 41, Issue:15

    Topics: Antineoplastic Agents; Binding Sites; Consensus Sequence; Dimethyl Sulfoxide; DNA, Neoplasm; Doxorub

2013
Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice.
    American journal of veterinary research, 2004, Volume: 65, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Dose-Response Relationship

2004
[Cytomorphological changes in human tumor cells exposed to high-polar compounds].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:11

    Topics: Cell Division; Cell Line; Dimethyl Sulfoxide; Dimethylformamide; Humans; Osteosarcoma; Sarcoma, Syno

1981
Apparent interaction of dimethyl sulfoxide with cisplatin released from polymer delivery devices injected subcutaneously in dogs.
    Journal of drug targeting, 1998, Volume: 5, Issue:5

    Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Bone Neoplasms; Cisplatin; Dimethyl Sulfoxi

1998
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
    Oncogene, 2001, Oct-25, Volume: 20, Issue:48

    Topics: Antigens, Neoplasm; Apoptosis; Base Sequence; Carcinoma; Cell Differentiation; Cell Division; Chromo

2001
Transformation of human osteosarcoma cells by a chemical carcinogen.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neopl

1975
[Changes in lectin-induced agglutination of human tumor cells during the process of their reversion].
    Eksperimental'naia onkologiia, 1985, Volume: 7, Issue:2

    Topics: Acetamides; Agglutination; Concanavalin A; Culture Media; Dimethyl Sulfoxide; Dimethylformamide; Dru

1985
Long-term preservation of permanent human hematopoietic cell lines.
    Journal of medicine, 1971, Volume: 2, Issue:6

    Topics: Cell Line; Cell Survival; Culture Media; Dimethyl Sulfoxide; Freezing; Hematopoietic Stem Cells; Hum

1971