dimethyl sulfoxide and Osteosarcoma
dimethyl sulfoxide has been researched along with Osteosarcoma in 11 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current treatment of high-grade osteosarcoma consists of preoperative chemotherapy, typically using some combination of doxorubicin, cisplatin, ifosfamide, and/or high-dose methotrexate followed by surgical resection." | 7.91 | Long-term Outcome After Doxorubicin and Ifosfamide Overdose in a Patient With Osteosarcoma and BARD1 Mutation. ( Savani, M; Skubitz, KM, 2019) |
| "To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation." | 7.72 | Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Current treatment of high-grade osteosarcoma consists of preoperative chemotherapy, typically using some combination of doxorubicin, cisplatin, ifosfamide, and/or high-dose methotrexate followed by surgical resection." | 3.91 | Long-term Outcome After Doxorubicin and Ifosfamide Overdose in a Patient With Osteosarcoma and BARD1 Mutation. ( Savani, M; Skubitz, KM, 2019) |
| " Human osteosarcoma MG63 cells were encapsulated in sodium alginate fiber constructs with wetspinning method and exposed to different formulations of cryopreservation media, containing dimethyl sulfoxide (DMSO), glycerol, and trehalose." | 3.88 | Effect of Cryopreservation on Cell-Laden Hydrogels: Comparison of Different Cryoprotectants. ( Bonani, W; Cagol, N; Maniglio, D; Migliaresi, C; Motta, A, 2018) |
| "To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation." | 3.72 | Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice. ( Baldwin, JM; Detrisac, CJ; Farese, JP; Fox, LE; Roberts, SL; Van Gilder, JM, 2004) |
| " Treatment of human melanoma cells with recombinant fibroblast interferon (IFN-beta) and the protein kinase C activator mezerein (MEZ) results in an irreversible loss in growth potential, suppression of tumorigenic properties and induction of terminal cell differentiation." | 3.71 | Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. ( Alexandre, D; Chada, S; Chen, Y; Christiansen, KA; Fisher, PB; Goldstein, NI; Gopalkrishnan, RV; Huang, EY; Huberman, E; Jiang, H; Kang, D; Lebedeva, IV; Leszczyniecka, M; Lin, JJ; Madireddi, MT; Mei, MX; Mhashilkar, AB; Pestka, S; Sivo, F; Su, Z; Vozhilla, N, 2001) |
| "The concanavalin A-induced agglutination of cultivated cells of human osteosarcoma Sa-4 was studied in the process of their reversion caused by high polar compounds, dimethylsulphoxide (DMSO) and dimethylformamide (DMFA)." | 3.67 | [Changes in lectin-induced agglutination of human tumor cells during the process of their reversion]. ( Viadro, MM, 1985) |
| "A human osteosarcoma clonal cell line (TE-85, clone F-5) was treated in vitro with various levels of 7,12-dimethylbenz[a]anthracene or dimethyl sulfoxide (control)." | 3.65 | Transformation of human osteosarcoma cells by a chemical carcinogen. ( Arnstein, P; Huebner, RJ; Kim, CM; Nelson Ress, WA; Rhim, JS; Weisburger, EK, 1975) |
Research
Studies (11)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Cagol, N | 1 |
| Bonani, W | 1 |
| Maniglio, D | 1 |
| Migliaresi, C | 1 |
| Motta, A | 1 |
| Savani, M | 1 |
| Skubitz, KM | 1 |
| Menendez, D | 1 |
| Nguyen, TA | 1 |
| Freudenberg, JM | 1 |
| Mathew, VJ | 1 |
| Anderson, CW | 1 |
| Jothi, R | 1 |
| Resnick, MA | 1 |
| Farese, JP | 1 |
| Fox, LE | 1 |
| Detrisac, CJ | 1 |
| Van Gilder, JM | 1 |
| Roberts, SL | 1 |
| Baldwin, JM | 1 |
| Viadro, MM | 2 |
| Tikhomirova, EE | 1 |
| Timofeevskaia, EA | 1 |
| Dernell, WS | 1 |
| Straw, RC | 1 |
| Withrow, SJ | 1 |
| Powers, BE | 1 |
| Fujita, SM | 1 |
| Yewey, GS | 1 |
| Joseph, KF | 1 |
| Dunn, RL | 1 |
| Whitman, SL | 1 |
| Southard, GL | 1 |
| Huang, EY | 1 |
| Madireddi, MT | 1 |
| Gopalkrishnan, RV | 1 |
| Leszczyniecka, M | 1 |
| Su, Z | 1 |
| Lebedeva, IV | 1 |
| Kang, D | 1 |
| Jiang, H | 1 |
| Lin, JJ | 1 |
| Alexandre, D | 1 |
| Chen, Y | 1 |
| Vozhilla, N | 1 |
| Mei, MX | 1 |
| Christiansen, KA | 1 |
| Sivo, F | 1 |
| Goldstein, NI | 1 |
| Mhashilkar, AB | 1 |
| Chada, S | 1 |
| Huberman, E | 1 |
| Pestka, S | 1 |
| Fisher, PB | 1 |
| Rhim, JS | 1 |
| Kim, CM | 1 |
| Arnstein, P | 1 |
| Huebner, RJ | 1 |
| Weisburger, EK | 1 |
| Nelson Ress, WA | 1 |
| Mizrahi, A | 1 |
| Moore, GE | 1 |
Reviews
1 review available for dimethyl sulfoxide and Osteosarcoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Trials
1 trial available for dimethyl sulfoxide and Osteosarcoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Other Studies
10 other studies available for dimethyl sulfoxide and Osteosarcoma
| Article | Year |
|---|---|
Effect of Cryopreservation on Cell-Laden Hydrogels: Comparison of Different Cryoprotectants.
Topics: Alginates; Apoptosis; Bone Neoplasms; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; G | 2018 |
Long-term Outcome After Doxorubicin and Ifosfamide Overdose in a Patient With Osteosarcoma and BARD1 Mutation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cardiotoxicity; Dimethyl Sulf | 2019 |
Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells.
Topics: Antineoplastic Agents; Binding Sites; Consensus Sequence; Dimethyl Sulfoxide; DNA, Neoplasm; Doxorub | 2013 |
Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice.
Topics: Angiogenesis Inhibitors; Animals; Dimethyl Sulfoxide; Dog Diseases; Dogs; Dose-Response Relationship | 2004 |
[Cytomorphological changes in human tumor cells exposed to high-polar compounds].
Topics: Cell Division; Cell Line; Dimethyl Sulfoxide; Dimethylformamide; Humans; Osteosarcoma; Sarcoma, Syno | 1981 |
Apparent interaction of dimethyl sulfoxide with cisplatin released from polymer delivery devices injected subcutaneously in dogs.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Bone Neoplasms; Cisplatin; Dimethyl Sulfoxi | 1998 |
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
Topics: Antigens, Neoplasm; Apoptosis; Base Sequence; Carcinoma; Cell Differentiation; Cell Division; Chromo | 2001 |
Transformation of human osteosarcoma cells by a chemical carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neopl | 1975 |
[Changes in lectin-induced agglutination of human tumor cells during the process of their reversion].
Topics: Acetamides; Agglutination; Concanavalin A; Culture Media; Dimethyl Sulfoxide; Dimethylformamide; Dru | 1985 |
Long-term preservation of permanent human hematopoietic cell lines.
Topics: Cell Line; Cell Survival; Culture Media; Dimethyl Sulfoxide; Freezing; Hematopoietic Stem Cells; Hum | 1971 |