Page last updated: 2024-10-18

dimethyl sulfoxide and Niemann-Pick Disease

dimethyl sulfoxide has been researched along with Niemann-Pick Disease in 8 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patterson, MC1
Di Bisceglie, AM1
Higgins, JJ1
Abel, RB1
Schiffmann, R1
Parker, CC1
Argoff, CE2
Grewal, RP1
Yu, K1
Pentchev, PG2
Scalco, FB1
Giugliani, R1
Tobo, P1
Coelho, JC1
Yoshikawa, H1
Hashimoto, K1
Koeda, T1
Matsubara, K1
Ohta, S1
Ohno, K1
Ohmura, K2
Blanchette Mackie, EJ1
Dwyer, NK1
Vanier, MT1
Sokol, J1
Merrick, HF1
Comly, ME1
Sato, M2
Yoshida, Y2
Sakuragawa, N3
Arima, M2
Kamo, I1
Satoyoshi, E1
Suzuki, K1
Miyazato, Y1

Trials

1 trial available for dimethyl sulfoxide and Niemann-Pick Disease

ArticleYear
The effect of cholesterol-lowering agents on hepatic and plasma cholesterol in Niemann-Pick disease type C.
    Neurology, 1993, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Anticholesteremic Agents; Child; Child, Preschool; Cholesterol; Cholestyramine Re

1993

Other Studies

7 other studies available for dimethyl sulfoxide and Niemann-Pick Disease

ArticleYear
Effect of dimethylsulfoxide on sphingomyelinase activity and cholesterol metabolism in Niemann-Pick type C fibroblasts.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1999, Volume: 32, Issue:1

    Topics: Analysis of Variance; Cells, Cultured; Cholesterol; Dimethyl Sulfoxide; Fibroblasts; Humans; Niemann

1999
Effects of drugs on cholesterol esterification in normal and Niemann-Pick type C fibroblasts: AY-9944, other cationic amphiphilic drugs and DMSO.
    Brain & development, 1991, Volume: 13, Issue:2

    Topics: Cations; Cells, Cultured; Cholesterol Esters; Dimethyl Sulfoxide; Esterification; Fibroblasts; Histo

1991
[A case of type C Niemann-Pick disease].
    No to hattatsu = Brain and development, 1990, Volume: 22, Issue:4

    Topics: Child, Preschool; Cholesterol; Dimethyl Sulfoxide; Esterification; Fibroblasts; Humans; Male; Nieman

1990
Type C Niemann-Pick disease: dimethyl sulfoxide moderates abnormal LDL-cholesterol processing in mutant fibroblasts.
    Biochimica et biophysica acta, 1989, Nov-28, Volume: 1006, Issue:2

    Topics: Cells, Cultured; Cholesterol, LDL; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Fibroblasts

1989
Effects of dimethylsulfoxide on sphingomyelinase activities in normal and Niemann-Pick type A, B and C fibroblasts.
    Biochimica et biophysica acta, 1988, Sep-02, Volume: 962, Issue:1

    Topics: Cell Line; Cycloheximide; Dimethyl Sulfoxide; Enzyme Activation; Fibroblasts; Humans; Hydrogen-Ion C

1988
Effects of dimethylsulfoxide on sphingomyelinase in cultured human fibroblasts and correction of sphingomyelinase deficiency in fibroblasts from Niemann-Pick patients.
    Biochemical and biophysical research communications, 1985, Jan-31, Volume: 126, Issue:2

    Topics: Cell Division; Cells, Cultured; Dimethyl Sulfoxide; Enzyme Induction; Fibroblasts; Humans; Hydrolase

1985
Clinical improvement with DMSO treatment in a patient with Niemann-Pick disease (type C).
    Acta paediatrica Japonica : Overseas edition, 1988, Volume: 30, Issue:4

    Topics: Child; Dimethyl Sulfoxide; Female; Humans; Niemann-Pick Diseases

1988