dimethyl sulfoxide has been researched along with Neurofibromatosis 1 in 2 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Galenic dural arteriovenous fistula (GDAVF) represents a unique, hard-to-treat subgroup of tentorial dural arteriovenous fistulae." | 1.51 | Galenic dural arteriovenous fistula in neurofibromatosis type 1 treated with Onyx. ( Du, Y; Han, Z; Qi, H, 2019) |
| "A 50-year-old man with neurofibromatosis type 1 presented to the emergency department after a spontaneous hemorrhage into a facial plexiform neurofibroma." | 1.39 | Spontaneous hemorrhage of a facial neurofibroma: endovascular embolization before surgical intervention. ( Gandhi, CD; Gupta, V; Prestigiacomo, CJ; Tomei, KL, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, Z | 1 |
| Du, Y | 1 |
| Qi, H | 1 |
| Tomei, KL | 1 |
| Gupta, V | 1 |
| Prestigiacomo, CJ | 1 |
| Gandhi, CD | 1 |
2 other studies available for dimethyl sulfoxide and Neurofibromatosis 1
| Article | Year |
|---|---|
Galenic dural arteriovenous fistula in neurofibromatosis type 1 treated with Onyx.
Topics: Adult; Central Nervous System Vascular Malformations; Cerebral Angiography; Dimethyl Sulfoxide; Embo | 2019 |
Spontaneous hemorrhage of a facial neurofibroma: endovascular embolization before surgical intervention.
Topics: Dimethyl Sulfoxide; Embolization, Therapeutic; Facial Neoplasms; Hemorrhage; Humans; Male; Middle Ag | 2013 |