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dimethyl sulfoxide and Neurofibromatosis 1

dimethyl sulfoxide has been researched along with Neurofibromatosis 1 in 2 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).

Research Excerpts

ExcerptRelevanceReference
"Galenic dural arteriovenous fistula (GDAVF) represents a unique, hard-to-treat subgroup of tentorial dural arteriovenous fistulae."1.51Galenic dural arteriovenous fistula in neurofibromatosis type 1 treated with Onyx. ( Du, Y; Han, Z; Qi, H, 2019)
"A 50-year-old man with neurofibromatosis type 1 presented to the emergency department after a spontaneous hemorrhage into a facial plexiform neurofibroma."1.39Spontaneous hemorrhage of a facial neurofibroma: endovascular embolization before surgical intervention. ( Gandhi, CD; Gupta, V; Prestigiacomo, CJ; Tomei, KL, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, Z1
Du, Y1
Qi, H1
Tomei, KL1
Gupta, V1
Prestigiacomo, CJ1
Gandhi, CD1

Other Studies

2 other studies available for dimethyl sulfoxide and Neurofibromatosis 1

ArticleYear
Galenic dural arteriovenous fistula in neurofibromatosis type 1 treated with Onyx.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2019, Volume: 25, Issue:6

    Topics: Adult; Central Nervous System Vascular Malformations; Cerebral Angiography; Dimethyl Sulfoxide; Embo

2019
Spontaneous hemorrhage of a facial neurofibroma: endovascular embolization before surgical intervention.
    The Journal of craniofacial surgery, 2013, Volume: 24, Issue:5

    Topics: Dimethyl Sulfoxide; Embolization, Therapeutic; Facial Neoplasms; Hemorrhage; Humans; Male; Middle Ag

2013