dimethyl sulfoxide has been researched along with Neuroectodermal Tumors, Primitive in 1 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Neuroectodermal Tumors, Primitive: A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The highest bioavailability was obtained with busulphan in DMSO administered i." | 1.30 | Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations. ( Boland, I; Gouyette, A; Hartmann, O; Kalifa, C; Morizet, J; Terrier-Lacombe, MJ; Valteau-Couanet, D; Vassal, G, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boland, I | 1 |
| Vassal, G | 1 |
| Morizet, J | 1 |
| Terrier-Lacombe, MJ | 1 |
| Valteau-Couanet, D | 1 |
| Kalifa, C | 1 |
| Hartmann, O | 1 |
| Gouyette, A | 1 |
1 other study available for dimethyl sulfoxide and Neuroectodermal Tumors, Primitive
| Article | Year |
|---|---|
Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations.
Topics: Administration, Oral; Animals; Biological Availability; Brain Neoplasms; Busulfan; Carboxymethylcell | 1999 |