dimethyl sulfoxide has been researched along with Nerve Degeneration in 9 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The safety and tolerability of a free radical scavenger with Na+ channel blocking activity (dimethyl sulfoxide (DMSO)) combined with a glycolytic intermediate and high energy substrate (fructose 1,6-disphosphate (FDP)) were assessed in a mostly elderly patient group presenting with acute and subacute ischemic stroke." | 5.10 | Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial. ( de la Torre, JC; Demir, S; Karaça, M; Kiliç, E; Yazici, B, 2002) |
| "Dimethyl sulfoxide (DMSO) is a solvent that is routinely used as a cryopreservative in allogous bone marrow and organ transplantation." | 1.35 | Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system. ( Farber, NB; Hanslick, JL; Lau, K; Mennerick, S; Noguchi, KK; Olney, JW; Zorumski, CF, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Giorgio, AM | 1 |
| Hou, Y | 1 |
| Zhao, X | 1 |
| Zhang, B | 1 |
| Lyeth, BG | 1 |
| Russell, MJ | 1 |
| Hanslick, JL | 1 |
| Lau, K | 1 |
| Noguchi, KK | 1 |
| Olney, JW | 1 |
| Zorumski, CF | 1 |
| Mennerick, S | 1 |
| Farber, NB | 1 |
| Henschen, A | 1 |
| Olson, L | 1 |
| de la Torre, JC | 2 |
| Fukuchi, K | 1 |
| Sopher, B | 1 |
| Furlong, CE | 1 |
| Smith, AC | 1 |
| Dang, N | 1 |
| Martin, GM | 1 |
| Hiraide, T | 1 |
| Katsura, K | 1 |
| Muramatsu, H | 1 |
| Asano, G | 1 |
| Katayama, Y | 1 |
| Karaça, M | 1 |
| Kiliç, E | 1 |
| Yazici, B | 1 |
| Demir, S | 1 |
| Blakemore, WF | 1 |
| Cavanagh, JB | 1 |
| Knott, LW | 1 |
| Katz, J | 1 |
| Rubinstein, LJ | 1 |
1 trial available for dimethyl sulfoxide and Nerve Degeneration
| Article | Year |
|---|---|
Ischemic stroke in elderly patients treated with a free radical scavenger-glycolytic intermediate solution: a preliminary pilot trial.
Topics: Adult; Aged; Aging; Brain; Brain Edema; Cerebrovascular Circulation; Dimethyl Sulfoxide; Drug Combin | 2002 |
8 other studies available for dimethyl sulfoxide and Nerve Degeneration
| Article | Year |
|---|---|
Dimethyl sulfoxide provides neuroprotection in a traumatic brain injury model.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Brain; Brain Injuries; Dimethyl Sulfoxide; Disease | 2008 |
Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Cells, Cultured; Dimethyl Sulfoxide; | 2009 |
Hexachlorophene-induced degeneration of adrenergic nerves: application of quantitative image analysis to Falck-Hillarp fluorescence histochemistry.
Topics: Animals; Axons; Computers; Dimethyl Sulfoxide; Female; Hexachlorophene; Histocytochemistry; Iris; Ma | 1983 |
Treatment of head injury in mice, using a fructose 1,6-diphosphate and dimethyl sulfoxide combination.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Brain; Cerebral Cortex; Dimethyl Sulfoxi | 1995 |
Selective neurotoxicity of COOH-terminal fragments of the beta-amyloid precursor protein.
Topics: Amyloid beta-Protein Precursor; Animals; Blotting, Western; Cell Differentiation; Cell Line; Cell Su | 1993 |
Adenosine receptor antagonists cancelled the ischemic tolerance phenomenon in gerbil.
Topics: Animals; Brain Ischemia; Dimethyl Sulfoxide; Free Radical Scavengers; Gerbillinae; Hippocampus; Isch | 2001 |
"Neuroaxonal dystrophy" occurring in an experimental "dying back" process in the rat.
Topics: Animals; Axons; Dimethyl Sulfoxide; Male; Microscopy, Electron; Mitosis; Nerve Degeneration; Nerve F | 1969 |
Separate and combined effects of phenol, hyaluronidase, and dimethyl sulfoxide on the sciatic nerve of the rat. II. Chronic studies.
Topics: Animals; Axons; Dimethyl Sulfoxide; Drug Synergism; Follow-Up Studies; Hyaluronoglucosaminidase; Ner | 1969 |